{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:33:53Z","timestamp":1772120033925,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Nucl Med"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1007\/s12149-024-01913-9","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T16:42:57Z","timestamp":1710348177000},"page":"369-381","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Improvement in the estimation of perfusable tissue fraction and myocardial flow reserve in the ischemic myocardial lesions using ECG-gated dynamic myocardial PET with 15O-water"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5722-3922","authenticated-orcid":false,"given":"Ayaka","family":"Maruo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Magota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yamato","family":"Munakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chietsugu","family":"Katoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,13]]},"reference":[{"key":"1913_CR1","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.2967\/jnumed.114.151894","volume":"56","author":"M Lubberink","year":"2015","unstructured":"Lubberink M, Golla SSV, Jonasson M, Rubin K, Glimelius B, Sorensen J, et al. 15O-water PET study of the effect of imatinib, a selective platelet-derived growth factor receptor inhibitor, versus anakinra, an IL-1R antagonist, on water-perfusable tissue fraction in colorectal cancer metastases. J Nucl Med. 2015;56:1144\u20139. https:\/\/doi.org\/10.2967\/jnumed.114.151894.","journal-title":"J Nucl Med"},{"key":"1913_CR2","doi-asserted-by":"publisher","first-page":"7481","DOI":"10.1088\/0031-9155\/57\/22\/7481","volume":"57","author":"Y Hirano","year":"2012","unstructured":"Hirano Y, Koshino K, Watabe H, Fukushima K, Iida H. Monte Carlo estimation of scatter effects on quantitative myocardial blood flow and perfusable tissue fraction using 3D-PET and (15)O-water. Phys Med Biol. 2012;57:7481\u201392. https:\/\/doi.org\/10.1088\/0031-9155\/57\/22\/7481.","journal-title":"Phys Med Biol"},{"key":"1913_CR3","first-page":"1219","volume":"46","author":"H Watabe","year":"2005","unstructured":"Watabe H, Jino H, Kawachi N, Teramoto N, Hayashi T, Ohta Y, et al. Parametric imaging of myocardial blood flow with 15O-water and PET using the basis function method. J Nucl Med. 2005;46:1219\u201324.","journal-title":"J Nucl Med"},{"key":"1913_CR4","first-page":"1299","volume":"45","author":"P Knaapen","year":"2004","unstructured":"Knaapen P, Boellaard R, Gotte MJW, Dijkmans PA, van Campen LMC, de Cock CC, et al. Perfusable tissue index as a potential marker of fibrosis in patients with idiopathic dilated cardiomyopathy. J Nucl Med. 2004;45:1299\u2013304.","journal-title":"J Nucl Med"},{"key":"1913_CR5","first-page":"33","volume":"44","author":"WM Schaefer","year":"2003","unstructured":"Schaefer WM, Nowak B, Kaiser HJ, Koch KC, Block S, vom Dahl J, et al. Comparison of microsphere-equivalent blood flow (15O-water PET) and relative perfusion (99mTc-tetrofosmin SPECT) in myocardium showing metabolism-perfusion mismatch. J Nucl Med. 2003;44:33\u20139.","journal-title":"J Nucl Med"},{"key":"1913_CR6","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1067\/mnc.2003.128743","volume":"10","author":"B Nowak","year":"2003","unstructured":"Nowak B, Schaefer WM, Koch KC, Kaiser HJ, Block S, Knackstedt C, et al. Assessment of myocardial viability in dysfunctional myocardium by resting myocardial blood flow determined with oxygen 15 water PET. J Nucl Cardiol. 2003;10:34\u201345. https:\/\/doi.org\/10.1067\/mnc.2003.128743.","journal-title":"J Nucl Cardiol"},{"key":"1913_CR7","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1008\/s00259-002-0793-6","volume":"29","author":"JJ Bax","year":"2002","unstructured":"Bax JJ, Fath-Ordoubadi F, Boersma E, Wijns W, Camici PG. Accuracy of PET in predicting functional recovery after revascularisation in patients with chronic ischaemic dysfunction: Head-to-head comparison between blood flow, glucose utilisation and water-perfusable tissue fraction. Eur J Nucl Med-Mol Imaging. 2002;29:721\u20137. https:\/\/doi.org\/10.1008\/s00259-002-0793-6.","journal-title":"Eur J Nucl Med-Mol Imaging"},{"key":"1913_CR8","first-page":"1737","volume":"41","author":"H Iida","year":"2000","unstructured":"Iida H, Tamura Y, Kitamura K, Bloomfield PM, Eberl S, Ono Y. Histochemical correlates of (15)O-water-perfusable tissue fraction in experimental canine studies of old myocardial infarction. J Nucl Med. 2000;41:1737\u201345.","journal-title":"J Nucl Med"},{"key":"1913_CR9","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1097\/00004647-200008000-00010","volume":"20","author":"I Law","year":"2000","unstructured":"Law I, Iida H, Holm S, Nour S, Rostrup E, Svarer C, et al. Quantitation of regional cerebral blood flow corrected for partial volume effect using O-15 water and PET: II. Normal values and gray matter blood flow response to visual activation. J Cereb Blood Flow Metab. 2000;20:1252\u201363. https:\/\/doi.org\/10.1097\/00004647-200008000-00010.","journal-title":"J Cereb Blood Flow Metab."},{"key":"1913_CR10","first-page":"1655","volume":"39","author":"BL Gerber","year":"1998","unstructured":"Gerber BL, Melin JA, Bol A, Labar D, Cogneau M, Michel C, et al. Nitrogen-13-ammonia and oxygen-15-water estimates of absolute myocardial perfusion in left ventricular ischemic dysfunction. J Nucl Med. 1998;39:1655\u201362.","journal-title":"J Nucl Med"},{"key":"1913_CR11","first-page":"78","volume":"36","author":"H Iida","year":"1995","unstructured":"Iida H, Takahashi A, Tamura Y, Ono Y, Lammertsma AA. Myocardial blood flow: Comparison of oxygen-15-water bolus injection, slow infusion and oxygen-15-carbon dioxide slow inhalation. J Nucl Med. 1995;36:78\u201385.","journal-title":"J Nucl Med"},{"key":"1913_CR12","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1007\/s12149-012-0631-2","volume":"26","author":"H Iida","year":"2012","unstructured":"Iida H, Ruotsalainen U, M\u00e4ki M, Haaparnata M, Bergman J, Voipio-Pulkki LM, et al. F-18 fluorodeoxyglucose uptake and water-perfusable tissue fraction in assessment of myocardial viability. Ann Nucl Med. 2012;26:644\u201355. https:\/\/doi.org\/10.1007\/s12149-012-0631-2.","journal-title":"Ann Nucl Med"},{"key":"1913_CR13","first-page":"2169","volume":"32","author":"H Iida","year":"1991","unstructured":"Iida H, Rhodes CG, de Silva R, Yamamoto Y, Araujo LI, Maseri A, et al. Myocardial tissue fraction\u2013Correction for partial volume effects and measure of tissue viability. J Nucl Med. 1991;32:2169\u201375.","journal-title":"J Nucl Med"},{"key":"1913_CR14","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1093\/cvr\/cvy169","volume":"115","author":"T Aikawa","year":"2019","unstructured":"Aikawa T, Naya M, Obara M, Manabe O, Magota K, Koyanagawa K, et al. Effects of coronary revascularization on global coronary flow reserve in stable coronary artery disease. Cardiovasc Res. 2019;115:119\u201329. https:\/\/doi.org\/10.1093\/cvr\/cvy169.","journal-title":"Cardiovasc Res"},{"key":"1913_CR15","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1007\/s12350-012-9522-0","volume":"19","author":"K Koshino","year":"2012","unstructured":"Koshino K, Watabe H, Enmi J, Hirano Y, Zeniya T, Hasegawa S, et al. Effects of patient movement on measurements of myocardial blood flow and viability in resting 15O-water PET studies. J Nucl Cardiol. 2012;19:524\u201333. https:\/\/doi.org\/10.1007\/s12350-012-9522-0.","journal-title":"J Nucl Cardiol"},{"key":"1913_CR16","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1007\/s00259-012-2134-8","volume":"39","author":"S De Haan","year":"2012","unstructured":"De Haan S, Harms HJ, Lubberink M, Allaart CP, Danad I, Chen WJY, et al. Parametric imaging of myocardial viability using 15O-labelled water and PET\/CT: comparison with late gadolinium-enhanced CMR. Eur J Nucl Med Mol Imaging. 2012;39:1240\u20135. https:\/\/doi.org\/10.1007\/s00259-012-2134-8.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1913_CR17","doi-asserted-by":"publisher","first-page":"60","DOI":"10.2967\/jnumed.110.080408","volume":"52","author":"M Lubberink","year":"2011","unstructured":"Lubberink M, Wong YY, Raijmakers PGHM, Schuit RC, Luurtsema G, Boellaard R, et al. Myocardial oxygen extraction fraction measured using bolus inhalation of 15O-oxygen gas and dynamic PET. J Nucl Med. 2011;52:60\u20136. https:\/\/doi.org\/10.2967\/jnumed.110.080408.","journal-title":"J Nucl Med"},{"key":"1913_CR18","doi-asserted-by":"publisher","first-page":"575","DOI":"10.2967\/jnumed.109.070748","volume":"51","author":"M Lubberink","year":"2010","unstructured":"Lubberink M, Harms HJ, Halbmeijer R, de Haan S, Knaapen P, Lammertsma AA. Low-dose quantitative myocardial blood flow imaging using 15O-water and PET without attenuation correction. J Nucl Med. 2010;51:575\u201380. https:\/\/doi.org\/10.2967\/jnumed.109.070748.","journal-title":"J Nucl Med"},{"key":"1913_CR19","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.nuclcard.2004.09.018","volume":"12","author":"G Frostfeldt","year":"2005","unstructured":"Frostfeldt G, Sorensen J, Lindahl B, Valind S, Wallentin L. Development of myocardial microcirculation and metabolism in acute ST-elevation myocardial infarction evaluated with positron emission tomography. J Nucl Cardiol. 2005;12:43\u201354.","journal-title":"J Nucl Cardiol"},{"key":"1913_CR20","first-page":"1687","volume":"46","author":"JS Lee","year":"2005","unstructured":"Lee JS, Lee DS, Ahn JY, Yeo JS, Cheon GJ, Kim S-K, et al. Generation of parametric image of regional myocardial blood flow using H(2)(15)O dynamic PET and a linear least-squares method. J Nucl Med. 2005;46:1687\u201395.","journal-title":"J Nucl Med"},{"key":"1913_CR21","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s11307-005-0007-2","volume":"7","author":"R Boellaard","year":"2005","unstructured":"Boellaard R, Knaapen P, Rijbroek A, Luurtsema GJJ, Lammertsma AA. Evaluation of basis function and linear least squares methods for generating parametric blood flow images using 15O-water and positron emission tomography. Mol Imaging Biol. 2005;7:273\u201385. https:\/\/doi.org\/10.1007\/s11307-005-0007-2.","journal-title":"Mol Imaging Biol"},{"key":"1913_CR22","first-page":"1908","volume":"45","author":"C Katoh","year":"2004","unstructured":"Katoh C, Morita K, Shiga T, Kubo N, Nakada K, Tamaki N. Improvement of algorithm for quantification of Regional Myocardial Blood Flow Using 15O-water with PET. J Nucl Med. 2004;45:1908\u201316.","journal-title":"J Nucl Med"},{"key":"1913_CR23","doi-asserted-by":"crossref","unstructured":"Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the cardiac imaging. Circulation. 2002;105:539\u201342.","DOI":"10.1161\/hc0402.102975"},{"key":"1913_CR24","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.2967\/jnumed.115.154377","volume":"56","author":"HJ Harms","year":"2015","unstructured":"Harms HJ, Lubberink M, de Haan S, Knaapen P, Huisman MC, Schuit RC, et al. Use of a single 11C-meta-hydroxyephedrine scan for assessing flow-innervation mismatches in patients with ischemic cardiomyopathy. J Nucl Med. 2015;56:1706\u201311. https:\/\/doi.org\/10.2967\/jnumed.115.154377.","journal-title":"J Nucl Med"}],"container-title":["Annals of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-024-01913-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12149-024-01913-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-024-01913-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,14]],"date-time":"2024-04-14T06:04:19Z","timestamp":1713074659000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12149-024-01913-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,13]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["1913"],"URL":"https:\/\/doi.org\/10.1007\/s12149-024-01913-9","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3070053\/v1","asserted-by":"object"}]},"ISSN":["0914-7187","1864-6433"],"issn-type":[{"value":"0914-7187","type":"print"},{"value":"1864-6433","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,13]]},"assertion":[{"value":"15 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures involving human participants performed in this study were in accordance with the ethical standards of the institutional and\/or national research committee and with the principles of the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all study participants.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}