{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T12:08:28Z","timestamp":1771589308654,"version":"3.50.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["6-2021-0069"],"award-info":[{"award-number":["6-2021-0069"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Nucl Med"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1007\/s12149-025-02122-8","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T10:56:29Z","timestamp":1762772189000},"page":"218-225","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and validation of a LASSO-Based FDG PET\/CT model for predicting colorectal adenoma in asymptomatic individuals undergoing colonoscopy"],"prefix":"10.1007","volume":"40","author":[{"given":"Jeonghyun","family":"Kang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youngmin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeongbeom","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Sun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Hoon","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Joo","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9898-9886","authenticated-orcid":false,"given":"Jae-Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"2122_CR1","first-page":"229","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74:229\u201363.","journal-title":"CA Cancer J Clin"},{"key":"2122_CR2","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1056\/NEJM199312303292701","volume":"329","author":"SJ Winawer","year":"1993","unstructured":"Winawer SJ, Zauber AG, Ho MN, O\u2019Brien MJ, Gottlieb LH, Sternberg SS, et al. Prevention of colorectal cancer by colonoscopic polypectomy. N Engl J Med. 1993;329:1977\u201381.","journal-title":"N Engl J Med"},{"key":"2122_CR3","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1053\/j.gastro.2012.06.001","volume":"143","author":"DA Lieberman","year":"2012","unstructured":"Lieberman DA, Rex DK, Winawer SJ, Giardiello FM, Johnson DA, Levin TR. Guidelines for colonoscopy surveillance after screening and polypectomy: a consensus update by the US multi-society task force on colorectal cancer. Gastroenterology. 2012;143:844\u201357.","journal-title":"Gastroenterology"},{"key":"2122_CR4","doi-asserted-by":"publisher","first-page":"458","DOI":"10.14309\/ajg.0000000000001122","volume":"116","author":"A Shaukat","year":"2021","unstructured":"Shaukat A, Kahi CJ, Burke CA, Rabeneck L, Sauer BG, Rex DK. ACG clinical guidelines: colorectal cancer screening 2021. Am J Gastroenterol. 2021;116:458\u201379.","journal-title":"Am J Gastroenterol"},{"key":"2122_CR5","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1001\/jama.2021.4417","volume":"325","author":"JS Lin","year":"2021","unstructured":"Lin JS, Perdue LA, Henrikson NB, Bean SI, Blasi PR. Screening for colorectal cancer: updated evidence report and systematic review for the US preventive services task force. JAMA. 2021;325:1978\u201398.","journal-title":"JAMA"},{"key":"2122_CR6","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.amepre.2010.01.020","volume":"38","author":"RM Jones","year":"2010","unstructured":"Jones RM, Woolf SH, Cunningham TD, Cook AJ, Krist AH, Johnson RE, et al. The relative importance of patient-reported barriers to colorectal cancer screening. Am J Prev Med. 2010;38:499\u2013507.","journal-title":"Am J Prev Med"},{"key":"2122_CR7","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1056\/NEJM200007203430302","volume":"343","author":"TF Imperiale","year":"2000","unstructured":"Imperiale TF, Wagner DR, Lin CY, Larkin GN, Rogge JD, Ransohoff DF. Risk of advanced proximal neoplasms in asymptomatic individuals according to the distal colorectal findings. N Engl J Med. 2000;343:169\u201374.","journal-title":"N Engl J Med"},{"key":"2122_CR8","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1136\/gut.2010.221168","volume":"60","author":"KG Yeoh","year":"2011","unstructured":"Yeoh KG, Ho KY, Chiu HM, Zhu F, Ho J, Wu WKW, et al. The Asia-Pacific colorectal screening score: a validated tool that stratifies risk for colorectal advanced neoplasia in asymptomatic Asian subjects. Gut. 2011;60:1236\u201341.","journal-title":"Gut"},{"key":"2122_CR9","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/j.crad.2015.03.010","volume":"70","author":"S Vaidyanathan","year":"2015","unstructured":"Vaidyanathan S, Patel CN, Scarsbrook AF, Chowdhury FU. FDG PET\/CT in infection and inflammation\u2014current and emerging clinical applications. Clin Radiol. 2015;70:787\u2013800.","journal-title":"Clin Radiol"},{"key":"2122_CR10","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1053\/j.semnuclmed.2021.06.008","volume":"51","author":"JP Pijl","year":"2021","unstructured":"Pijl JP, Nienhuis PH, Kwee TC, Glaudemans AWJM, Slart RHJA, Gormsen LC. Limitations and pitfalls of FDG-PET\/CT in infection and inflammation. Semin Nucl Med. 2021;51:633\u201345.","journal-title":"Semin Nucl Med"},{"key":"2122_CR11","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26051976","volume":"26","author":"AB Nelson","year":"2025","unstructured":"Nelson AB, Reese LE, Rono E, Queathem ED, Qiu Y, McCluskey BM, et al. Deciphering colorectal cancer\u2013hepatocyte interactions: a multiomics platform for interrogation of metabolic crosstalk in the liver\u2013tumor microenvironment. Int J Mol Sci. 2025;26:1976.","journal-title":"Int J Mol Sci"},{"key":"2122_CR12","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1053\/j.gastro.2010.01.058","volume":"138","author":"J Terzi\u0107","year":"2010","unstructured":"Terzi\u0107 J, Grivennikov S, Karin E, Karin M. Inflammation and colon cancer. Gastroenterology. 2010;138:2101\u201314.","journal-title":"Gastroenterology"},{"key":"2122_CR13","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13872","volume":"26","author":"AJ Ruiz-Malag\u00f3n","year":"2025","unstructured":"Ruiz-Malag\u00f3n AJ, Rodr\u00edguez-Sojo MJ, Redondo E, Rodr\u00edguez-Cabezas ME, G\u00e1lvez J, Rodr\u00edguez-Nogales A. Systematic review: the gut microbiota as a link between colorectal cancer and obesity. Obes Rev. 2025;26:e13872.","journal-title":"Obes Rev"},{"key":"2122_CR14","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-024-02108-6","volume":"23","author":"Y Chen","year":"2024","unstructured":"Chen Y, Liang J, Chen S, Zhang Q, Li R, Huang G. Discovery of vitexin as a novel VDR agonist that mitigates the transition from chronic intestinal inflammation to colorectal cancer. Mol Cancer. 2024;23:196.","journal-title":"Mol Cancer"},{"key":"2122_CR15","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1002\/jcsm.12430","volume":"10","author":"JY Kim","year":"2019","unstructured":"Kim JY, Jun DW, Choi J, Nam E, Son D, Choi YY. Psoas muscle fluorine-18-labelled fluoro-2-deoxy-d-glucose uptake associated with the incidence of existing and incipient metabolic derangement. J Cachexia Sarcopenia Muscle. 2019;10:894\u2013902.","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"2122_CR16","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.1007\/s00261-017-1418-7","volume":"43","author":"ID Yoo","year":"2018","unstructured":"Yoo ID, Lee SM, Lee JW, Baek MJ, Ahn TS. Usefulness of metabolic activity of adipose tissue in FDG PET\/CT of colorectal cancer. Abdom Radiol. 2018;43:2052\u20139.","journal-title":"Abdom Radiol"},{"key":"2122_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2018.07.094","volume":"73","author":"JW Lee","year":"2018","unstructured":"Lee JW, Lee SM, Chung YA. Prognostic value of CT attenuation and FDG uptake of adipose tissue in patients with pancreatic adenocarcinoma. Clin Radiol. 2018;73:e10561\u2013105610.","journal-title":"Clin Radiol"},{"key":"2122_CR18","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-91608-2","volume":"11","author":"JH Lee","year":"2021","unstructured":"Lee JH, Lee HS, Kim S, Park EJ, Baik SH, Jeon TJ, et al. Prognostic significance of bone marrow and spleen 18F-FDG uptake in patients with colorectal cancer. Sci Rep. 2021;11:12137.","journal-title":"Sci Rep"},{"key":"2122_CR19","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-024-05806-2","volume":"150","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Han J, Li J, Liu H, Gao Y, Liu L. Clinical significance of 18F-FDG-PET\/CT for detection of incidental pre-malignant and malignant colonic lesions: correlation with colonoscopic and histopathological results. J Cancer Res Clin Oncol. 2024;150:265.","journal-title":"J Cancer Res Clin Oncol"},{"key":"2122_CR20","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000007156","volume":"96","author":"HJ Yoon","year":"2017","unstructured":"Yoon HJ, Kim BS, Lee KE, Park J, Ahn SG, Lee JH. Glucose metabolism of visceral adipose tissue measured by 18F-FDG PET\/CT is related to the presence of colonic adenoma. Medicine (Baltimore). 2017;96:e7156.","journal-title":"Medicine (Baltimore)"},{"key":"2122_CR21","doi-asserted-by":"publisher","first-page":"4786","DOI":"10.1158\/0008-5472.CAN-18-0125","volume":"78","author":"C Nioche","year":"2018","unstructured":"Nioche C, Orlhac F, Boughdad S, Zedek S, Prochazka M, Dygai-Cook C, et al. LIFEx: a freeware for radiomic feature calculation in multimodality imaging to accelerate advances in the characterization of tumor heterogeneity. Cancer Res. 2018;78:4786\u20139.","journal-title":"Cancer Res"},{"key":"2122_CR22","doi-asserted-by":"publisher","first-page":"e230024","DOI":"10.1148\/ryai.230024","volume":"5","author":"J Wasserthal","year":"2023","unstructured":"Wasserthal J, Breit HC, Meyer MT, Langbein TJ, O\u2019Brien KR, Ruscheinski J, et al. TotalSegmentator: robust segmentation of 104 anatomic structures in CT images. Radiol Artif Intell. 2023;5:e230024.","journal-title":"Radiol Artif Intell"},{"key":"2122_CR23","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/s41592-020-01008-z","volume":"18","author":"F Isensee","year":"2021","unstructured":"Isensee F, Jaeger PF, Kohl SAA, Petersen J, Maier-Hein KH. NnU-net: a self-configuring method for deep learning-based biomedical image segmentation. Nat Methods. 2021;18:203\u201311.","journal-title":"Nat Methods"},{"key":"2122_CR24","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-01086-9","volume":"11","author":"JH Lee","year":"2021","unstructured":"Lee JH, Lee HS, Kim S, Park EJ, Baik SH, Jeon TJ, et al. Different prognostic impact of glucose uptake in visceral adipose tissue according to sex in patients with colorectal cancer. Sci Rep. 2021;11:21556.","journal-title":"Sci Rep"},{"key":"2122_CR25","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1136\/gutjnl-2013-304701","volume":"62","author":"M Bardou","year":"2013","unstructured":"Bardou M, Barkun AN, Martel M. Obesity and colorectal cancer. Gut. 2013;62:933\u201347.","journal-title":"Gut"},{"key":"2122_CR26","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1038\/nrendo.2014.94","volume":"10","author":"J Park","year":"2014","unstructured":"Park J, Morley TS, Kim M, Clegg DJ, Scherer PE. Obesity and cancer\u2014mechanisms underlying tumour progression and recurrence. Nat Rev Endocrinol. 2014;10:455\u201365.","journal-title":"Nat Rev Endocrinol"},{"key":"2122_CR27","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s00259-007-0563-6","volume":"35","author":"E Gontier","year":"2008","unstructured":"Gontier E, Fourme E, Wartski M, Boyer A, Castelain V, Lassau N, et al. High and typical 18F-FDG bowel uptake in patients treated with Metformin. Eur J Nucl Med Mol Imaging. 2008;35:95\u20139.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"2122_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13550-017-0318-8","volume":"7","author":"JY Kang","year":"2017","unstructured":"Kang JY, Kim HN, Chang Y, Lee JY, Cheon JH, Lee JH, et al. Gut microbiota and physiologic bowel 18F-FDG uptake. EJNMMI Res. 2017;7:1\u201310.","journal-title":"EJNMMI Res"},{"key":"2122_CR29","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1148\/radiology.213.2.r99nv37521","volume":"213","author":"Y Sugawara","year":"1999","unstructured":"Sugawara Y, Zasadny KR, Neuhoff AW, Wahl RL. Reevaluation of the standardized uptake value for FDG: variations with body weight and methods for correction. Radiology. 1999;213:521\u20135.","journal-title":"Radiology"},{"key":"2122_CR30","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.2967\/jnumed.113.136986","volume":"55","author":"AK Tahari","year":"2014","unstructured":"Tahari AK, Chien D, Azadi JR, Wahl RL. Optimum lean body formulation for correction of standardized uptake value in PET imaging. J Nucl Med. 2014;55:1481\u20134.","journal-title":"J Nucl Med"}],"container-title":["Annals of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-025-02122-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12149-025-02122-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-025-02122-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T11:20:11Z","timestamp":1771586411000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12149-025-02122-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["2122"],"URL":"https:\/\/doi.org\/10.1007\/s12149-025-02122-8","relation":{},"ISSN":["0914-7187","1864-6433"],"issn-type":[{"value":"0914-7187","type":"print"},{"value":"1864-6433","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,10]]},"assertion":[{"value":"6 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}