{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:26:52Z","timestamp":1787668012826,"version":"build-2736575974"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Nucl Med"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s12149-026-02226-9","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T07:27:05Z","timestamp":1779175625000},"page":"1089-1097","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integration of \u2076\u2078Ga-DOTA-TOC PET\/CT into radiotherapy planning for intracranial meningiomas: A precision-imaging approach to tumor delineation"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9274-7571","authenticated-orcid":false,"given":"Sharjeel","family":"Usmani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Furqan","family":"Hashmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjali","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Al Saifi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asiya","family":"alBusaidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khulood Al","family":"Riyami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"issue":"suppl4","key":"2226_CR1","doi-asserted-by":"publisher","first-page":"iv1","DOI":"10.1093\/neuonc\/noy131","volume":"20","author":"QT Ostrom","year":"2018","unstructured":"Ostrom QT, Gittleman H, Truitt G, et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2011\u20132015. Neuro Oncol. 2018;20(suppl4):iv1\u201386.","journal-title":"Neuro Oncol"},{"key":"2226_CR2","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","volume":"131","author":"DN Louis","year":"2016","unstructured":"Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: A Summary. Acta Neuropathol. 2016;131:803\u201320.","journal-title":"Acta Neuropathol"},{"key":"2226_CR3","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s11060-010-0343-1","volume":"99","author":"L Rogers","year":"2010","unstructured":"Rogers L, Gilbert M, Vogelbaum MA. Intracranial meningiomas of atypical (WHO grade II) histology. J Neurooncol. 2010;99:393\u2013405.","journal-title":"J Neurooncol"},{"key":"2226_CR4","doi-asserted-by":"publisher","first-page":"e383","DOI":"10.1016\/S1470-2045(16)30321-7","volume":"17","author":"R Goldbrunner","year":"2016","unstructured":"Goldbrunner R, Minniti G, Preusser M, et al. EANO guidelines for the diagnosis and treatment of meningiomas. Lancet Oncol. 2016;17:e383\u201391.","journal-title":"Lancet Oncol"},{"key":"2226_CR5","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.yfrne.2013.07.005","volume":"34","author":"M Theodoropoulou","year":"2013","unstructured":"Theodoropoulou M, Stalla GK. Somatostatin receptors: from signaling to clinical practice. Front Neuroendocrinol. 2013;34:228\u201352.","journal-title":"Front Neuroendocrinol"},{"key":"2226_CR6","doi-asserted-by":"publisher","first-page":"347","DOI":"10.2967\/jnumed.114.149120","volume":"56","author":"W Rachinger","year":"2015","unstructured":"Rachinger W, Stoecklein VM, Terpolilli NA, et al. Increased 68Ga-DOTATATE uptake in PET imaging discriminates meningioma and tumor-free tissue. J Nucl Med. 2015;56:347\u201353.","journal-title":"J Nucl Med"},{"key":"2226_CR7","doi-asserted-by":"publisher","first-page":"2216","DOI":"10.1158\/1078-0432.CCR-20-3362","volume":"27","author":"A Bashir","year":"2021","unstructured":"Bashir A, Larsen VA, Ziebell M, et al. Improved Detection of Postoperative Residual Meningioma with [68Ga]Ga-DOTA-TOC PET Imaging Using a High-resolution Research Tomograph PET Scanner. Clin Cancer Res. 2021;27:2216\u201325.","journal-title":"Clin Cancer Res"},{"key":"2226_CR8","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1016\/j.ijrobp.2022.04.009","volume":"113","author":"HK Perlow","year":"2022","unstructured":"Perlow HK, Siedow M, Gokun Y, et al. 68Ga-DOTATATE PET-Based Radiation Contouring Creates More Precise Radiation Volumes for Patients With Meningioma. Int J Radiat Oncol Biol Phys. 2022;113:859\u201365.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2226_CR9","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.47391\/JPMA.23-44","volume":"73","author":"S Usmani","year":"2023","unstructured":"Usmani S, Jain A, Hashmi SF, et al. 68Ga-DOTA-peptide PET\/CT for radiotherapy planning and evaluating treatment response in the management of meningiomas. J Pak Med Assoc. 2023;73:1340\u20133.","journal-title":"J Pak Med Assoc"},{"issue":"12","key":"2226_CR10","doi-asserted-by":"publisher","first-page":"3662","DOI":"10.1007\/s00259-024-06783-x","volume":"51","author":"NL Albert","year":"2024","unstructured":"Albert NL, Preusser M, Traub-Weidinger T, et al. Joint EANM\/EANO\/RANO\/SNMMI practice guideline\/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor ligands: version 1.0. Eur J Nucl Med Mol Imaging. 2024;51(12):3662\u201379.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"10","key":"2226_CR11","doi-asserted-by":"publisher","first-page":"1742","DOI":"10.1093\/neuonc\/noae082","volume":"26","author":"JZ Wang","year":"2024","unstructured":"Wang JZ, Landry AP, Raleigh DR, et al. Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients. Neuro Oncol. 2024;26(10):1742\u201380.","journal-title":"Neuro Oncol"},{"key":"2226_CR12","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.ijrobp.2012.03.021","volume":"85","author":"R Graf","year":"2013","unstructured":"Graf R, Nyuyki F, Steffen IG, et al. Contribution of 68Ga-DOTATOC PET\/CT to target volume delineation of skull base meningiomas treated with stereotactic radiation therapy. Int J Radiat Oncol Biol Phys. 2013;85:68\u201373.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2226_CR13","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.ijrobp.2005.12.006","volume":"65","author":"S Milker-Zabel","year":"2006","unstructured":"Milker-Zabel S, Zabel-du Bois A, Henze M, et al. Improved target volume definition for fractionated stereotactic radiotherapy in patients with intracranial meningiomas by correlation of CT, MRI, and [68Ga]-DOTATOC-PET. Int J Radiat Oncol Biol Phys. 2006;65:222\u20137.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2226_CR14","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/s13014-021-01875-6","volume":"16","author":"ES Kowalski","year":"2021","unstructured":"Kowalski ES, Khairnar R, Gryaznov AA, et al. 68Ga-DOTATATE PET-CT as a tool for radiation planning and evaluating treatment responses in the clinical management of meningiomas. Radiat Oncol. 2021;16:151.","journal-title":"Radiat Oncol"},{"key":"2226_CR15","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1093\/neuonc\/nox112","volume":"19","author":"N Galldiks","year":"2017","unstructured":"Galldiks N, Albert NL, Sommerauer M, Grosu AL, Ganswindt U, Law I, Preusser M, Le Rhun E, Vogelbaum MA, Zadeh G, Dhermain F, Weller M, Langen KJ, Tonn JC. PET imaging in patients with meningioma-report of the RANO\/PET Group. Neuro Oncol. 2017;19:1576\u201387.","journal-title":"Neuro Oncol"},{"key":"2226_CR16","first-page":"152","volume":"34","author":"S Usmani","year":"2025","unstructured":"Usmani S, Jain A, Al Riyami K, Hashmi SF, Khalid J, Kheruka S. Molecular Perspectives on Meningioma with Osseous Infiltration Revealed by 68Ga-DOTA TOC PET-CT. Mol Imaging Radionucl Ther. 2025;34:152\u20135.","journal-title":"Mol Imaging Radionucl Ther"},{"key":"2226_CR17","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.2967\/jnumed.117.191932","volume":"58","author":"WG Kunz","year":"2017","unstructured":"Kunz WG, Jungblut LM, Kazmierczak PM, et al. Improved detection of transosseous meningiomas using (68)Ga-DOTATATE PET\/CT compared with contrast-enhanced MRI. J Nucl Med. 2017;58:1580\u20137.","journal-title":"J Nucl Med"},{"key":"2226_CR18","doi-asserted-by":"publisher","first-page":"4435","DOI":"10.3390\/cancers14184435","volume":"14","author":"F Kriwanek","year":"2022","unstructured":"Kriwanek F, Ulbrich L, Lechner W, et al. Impact of SSTR PET on Inter-Observer Variability of Target Delineation of Meningioma and the Possibility of Using Threshold-Based Segmentations in Radiation Oncology. Cancers (Basel). 2022;14:4435.","journal-title":"Cancers (Basel)"},{"key":"2226_CR19","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1007\/s00259-025-07476-9","volume":"53","author":"N Mansour","year":"2026","unstructured":"Mansour N, Joram J, Grawe F, et al. Validation of SUV thresholds in [\u00b9\u2078F]SiTATE PET\/CT for accurate meningioma segmentation. Eur J Nucl Med Mol Imaging. 2026;53:854\u201364.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"2226_CR20","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1007\/s12672-025-04079-6","volume":"16","author":"SC Kunte","year":"2025","unstructured":"Kunte SC, Unterrainer LM, Lindner S, et al. Feasibility of different meningioma delineation approaches on [18F]SiTATE PET\/CT imaging. Discov Oncol. 2025;16:2189.","journal-title":"Discov Oncol"}],"container-title":["Annals of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-026-02226-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12149-026-02226-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12149-026-02226-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:43:36Z","timestamp":1787665416000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12149-026-02226-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,19]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["2226"],"URL":"https:\/\/doi.org\/10.1007\/s12149-026-02226-9","relation":{},"ISSN":["0914-7187","1864-6433"],"issn-type":[{"value":"0914-7187","type":"print"},{"value":"1864-6433","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,19]]},"assertion":[{"value":"12 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedure performed in studies involving human participants were in accordance with the ethical standard of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Ethical approval was secured from the institutional review board.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from all participants.","order":3,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}