{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T05:57:08Z","timestamp":1722837428669},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,8,10]],"date-time":"2010-08-10T00:00:00Z","timestamp":1281398400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Hematol"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1007\/s12185-010-0653-2","type":"journal-article","created":{"date-parts":[[2010,8,9]],"date-time":"2010-08-09T04:10:22Z","timestamp":1281327022000},"page":"320-325","source":"Crossref","is-referenced-by-count":16,"title":["Absence of gain-of-function JAK1 and JAK3 mutations in adult T cell leukemia\/lymphoma"],"prefix":"10.1007","volume":"92","author":[{"given":"T.","family":"Kameda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Shide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. K.","family":"Shimoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Hidaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Kubuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Katayose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sekine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kamiunntenn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nagata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Matsunaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Shimoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,8,10]]},"reference":[{"key":"653_CR1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/sj.leu.2402777","volume":"17","author":"F Mortreux","year":"2003","unstructured":"Mortreux F, Gabet AS, Wattel E. Molecular and cellular aspects of HTLV-1 associated leukemogenesis in vivo. Leukemia. 2003;17:26\u201338.","journal-title":"Leukemia"},{"key":"653_CR2","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/rmv.548","volume":"17","author":"J Yasunaga","year":"2007","unstructured":"Yasunaga J, Matsuoka M. Leukaemogenic mechanism of human T-cell leukaemia virus type I. Rev Med Virol. 2007;17:301\u201311.","journal-title":"Rev Med Virol"},{"key":"653_CR3","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0092-8674(87)90437-5","volume":"48","author":"M Maruyama","year":"1987","unstructured":"Maruyama M, Shibuya H, Harada H, Hatakeyama M, Seiki M, Fujita T, et al. Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3\/Ti complex triggering. Cell. 1987;48:343\u201350.","journal-title":"Cell"},{"key":"653_CR4","doi-asserted-by":"crossref","first-page":"5389","DOI":"10.1073\/pnas.84.15.5389","volume":"84","author":"M Siekevitz","year":"1987","unstructured":"Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Proc Natl Acad Sci USA. 1987;84:5389\u201393.","journal-title":"Proc Natl Acad Sci USA"},{"key":"653_CR5","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1034\/j.1600-0609.2002.00653.x","volume":"68","author":"H Baba","year":"2002","unstructured":"Baba H, Yamada Y, Mori N, Hayashibara T, Harasawa H, Tsuruda K, et al. Multiple gammac-receptor expression in adult T-cell leukemia. Eur J Haematol. 2002;68:362\u20139.","journal-title":"Eur J Haematol"},{"key":"653_CR6","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/08830180701703364","volume":"26","author":"R Horie","year":"2007","unstructured":"Horie R. NF-kappaB in pathogenesis and treatment of adult T-cell leukemia\/lymphoma. Int Rev Immunol. 2007;26:269\u201381.","journal-title":"Int Rev Immunol"},{"key":"653_CR7","doi-asserted-by":"crossref","first-page":"13897","DOI":"10.1073\/pnas.94.25.13897","volume":"94","author":"S Takemoto","year":"1997","unstructured":"Takemoto S, Mulloy JC, Cereseto A, Migone TS, Patel BK, Matsuoka M, et al. Proliferation of adult T cell leukemia\/lymphoma cells is associated with the constitutive activation of JAK\/STAT proteins. Proc Natl Acad Sci USA. 1997;94:13897\u2013902.","journal-title":"Proc Natl Acad Sci USA"},{"key":"653_CR8","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1080\/10428190500244217","volume":"46","author":"Y Yamada","year":"2005","unstructured":"Yamada Y, Kamihira S. Inactivation of tumor suppressor genes and the progression of adult T-cell leukemia-lymphoma. Leuk Lymphoma. 2005;46:1553\u20139.","journal-title":"Leuk Lymphoma"},{"key":"653_CR9","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.3109\/10428190109097731","volume":"42","author":"WK Hofmann","year":"2001","unstructured":"Hofmann WK, Tsukasaki K, Takeuchi N, Takeuchi S, Koeffler HP. Methylation analysis of cell cycle control genes in adult T-cell leukemia\/lymphoma. Leuk Lymphoma. 2001;42:1107\u20139.","journal-title":"Leuk Lymphoma"},{"key":"653_CR10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1600-065X.2008.00754.x","volume":"228","author":"K Ghoreschi","year":"2009","unstructured":"Ghoreschi K, Laurence A, O\u2019Shea JJ. Janus kinases in immune cell signaling. Immunol Rev. 2009;228:273\u201387.","journal-title":"Immunol Rev"},{"key":"653_CR11","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.4049\/jimmunol.178.5.2623","volume":"178","author":"PJ Murray","year":"2007","unstructured":"Murray PJ. The JAK-STAT signaling pathway: input and output integration. J Immunol. 2007;178:2623\u20139.","journal-title":"J Immunol"},{"key":"653_CR12","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0092-8674(00)81166-6","volume":"93","author":"SJ Rodig","year":"1998","unstructured":"Rodig SJ, Meraz MA, White JM, Lampe PA, Riley JK, Arthur CD, et al. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell. 1998;93:373\u201383.","journal-title":"Cell"},{"key":"653_CR13","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0092-8674(00)81168-X","volume":"93","author":"H Neubauer","year":"1998","unstructured":"Neubauer H, Cumano A, Muller M, Wu H, Huffstadt U, Pfeffer K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell. 1998;93:397\u2013409.","journal-title":"Cell"},{"key":"653_CR14","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1126\/science.270.5237.794","volume":"270","author":"DC Thomis","year":"1995","unstructured":"Thomis DC, Gurniak CB, Tivol E, Sharpe AH, Berg LJ. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science. 1995;270:794\u20137.","journal-title":"Science"},{"key":"653_CR15","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/1074-7613(95)90066-7","volume":"3","author":"SY Park","year":"1995","unstructured":"Park SY, Saijo K, Takahashi T, Osawa M, Arase H, Hirayama N, et al. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity. 1995;3:771\u201382.","journal-title":"Immunity"},{"key":"653_CR16","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.278.5341.1309","volume":"278","author":"V Lacronique","year":"1997","unstructured":"Lacronique V, Boureux A, Valle VD, Poirel H, Quang CT, Mauchauffe M, et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science. 1997;278:1309\u201312.","journal-title":"Science"},{"key":"653_CR17","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1182\/blood.V90.7.2535","volume":"90","author":"P Peeters","year":"1997","unstructured":"Peeters P, Raynaud SD, Cools J, Wlodarska I, Grosgeorge J, Philip P, et al. Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. Blood. 1997;90:2535\u201340.","journal-title":"Blood"},{"key":"653_CR18","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1084\/jem.20072182","volume":"205","author":"E Flex","year":"2008","unstructured":"Flex E, Petrangeli V, Stella L, Chiaretti S, Hornakova T, Knoops L, et al. Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia. J Exp Med. 2008;205:751\u20138.","journal-title":"J Exp Med"},{"key":"653_CR19","doi-asserted-by":"crossref","first-page":"4809","DOI":"10.1182\/blood-2007-05-090308","volume":"111","author":"Z Xiang","year":"2008","unstructured":"Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, et al. Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood. 2008;111:4809\u201312.","journal-title":"Blood"},{"key":"653_CR20","doi-asserted-by":"crossref","first-page":"4797","DOI":"10.1182\/blood-2007-09-113027","volume":"111","author":"MH Tomasson","year":"2008","unstructured":"Tomasson MH, Xiang Z, Walgren R, Zhao Y, Kasai Y, Miner T, et al. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood. 2008;111:4797\u2013808.","journal-title":"Blood"},{"key":"653_CR21","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.ccr.2005.03.023","volume":"7","author":"RL Levine","year":"2005","unstructured":"Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387\u201397.","journal-title":"Cancer Cell"},{"key":"653_CR22","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/nrc2210","volume":"7","author":"RL Levine","year":"2007","unstructured":"Levine RL, Pardanani A, Tefferi A, Gilliland DG. Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders. Nat Rev Cancer. 2007;7:673\u201383.","journal-title":"Nat Rev Cancer"},{"key":"653_CR23","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/S0140-6736(08)61341-0","volume":"372","author":"D Bercovich","year":"2008","unstructured":"Bercovich D, Ganmore I, Scott LM, Wainreb G, Birger Y, Elimelech A, et al. Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down\u2019s syndrome. Lancet. 2008;372:1484\u201392.","journal-title":"Lancet"},{"key":"653_CR24","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ccr.2006.06.002","volume":"10","author":"DK Walters","year":"2006","unstructured":"Walters DK, Mercher T, Gu TL, O\u2019Hare T, Tyner JW, Loriaux M, et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell. 2006;10:65\u201375.","journal-title":"Cancer Cell"},{"key":"653_CR25","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1182\/blood-2008-06-164368","volume":"113","author":"MG Cornejo","year":"2009","unstructured":"Cornejo MG, Kharas MG, Werneck MB, Le Bras S, Moore SA, Ball B, et al. Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models. Blood. 2009;113:2746\u201354.","journal-title":"Blood"},{"key":"653_CR26","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1126\/science.7604283","volume":"269","author":"TS Migone","year":"1995","unstructured":"Migone TS, Lin JX, Cereseto A, Mulloy JC, O\u2019Shea JJ, Franchini G, et al. Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I. Science. 1995;269:79\u201381.","journal-title":"Science"},{"key":"653_CR27","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1365-2141.2007.06574.x","volume":"137","author":"S Vita De","year":"2007","unstructured":"De Vita S, Mulligan C, McElwaine S, Dagna-Bricarelli F, Spinelli M, Basso G, et al. Loss-of-function JAK3 mutations in TMD and AMKL of Down syndrome. Br J Haematol. 2007;137:337\u201341.","journal-title":"Br J Haematol"},{"key":"653_CR28","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-2141.1991.tb08051.x","volume":"79","author":"M Shimoyama","year":"1991","unstructured":"Shimoyama M. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984\u201387). Br J Haematol. 1991;79:428\u201337.","journal-title":"Br J Haematol"},{"key":"653_CR29","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/nature02168","volume":"426","author":"TIH Consortium","year":"2003","unstructured":"Consortium TIH. The international HapMap project. Nature. 2003;426:789\u201396.","journal-title":"Nature"},{"key":"653_CR30","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1038\/nature04226","volume":"437","author":"TIH Consortium","year":"2005","unstructured":"Consortium TIH. A haplotype map of the human genome. Nature. 2005;437:1299\u2013320.","journal-title":"Nature"},{"key":"653_CR31","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1126\/science.7973658","volume":"266","author":"SM Russell","year":"1994","unstructured":"Russell SM, Johnston JA, Noguchi M, Kawamura M, Bacon CM, Friedmann M, et al. Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID. Science. 1994;266:1042\u20135.","journal-title":"Science"},{"key":"653_CR32","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/370153a0","volume":"370","author":"BA Witthuhn","year":"1994","unstructured":"Witthuhn BA, Silvennoinen O, Miura O, Lai KS, Cwik C, Liu ET, et al. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature. 1994;370:153\u20137.","journal-title":"Nature"},{"key":"653_CR33","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0014-5793(94)01065-X","volume":"353","author":"YX Zeng","year":"1994","unstructured":"Zeng YX, Takahashi H, Shibata M, Hirokawa K. JAK3 Janus kinase is involved in interleukin 7 signal pathway. FEBS Lett. 1994;353:289\u201393.","journal-title":"FEBS Lett"},{"key":"653_CR34","doi-asserted-by":"crossref","first-page":"4408","DOI":"10.1128\/JVI.72.5.4408-4412.1998","volume":"72","author":"JC Mulloy","year":"1998","unstructured":"Mulloy JC, Migone TS, Ross TM, Ton N, Green PL, Leonard WJ, et al. Human and simian T-cell leukemia viruses type 2 (HTLV-2 and STLV-2(pan-p)) transform T cells independently of Jak\/STAT activation. J Virol. 1998;72:4408\u201312.","journal-title":"J Virol"},{"key":"653_CR35","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1742-4690-3-22","volume":"3","author":"M Tomita","year":"2006","unstructured":"Tomita M, Kawakami H, Uchihara JN, Okudaira T, Masuda M, Matsuda T, et al. Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Retrovirology. 2006;3:22.","journal-title":"Retrovirology"},{"key":"653_CR36","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0145-2126(98)00173-8","volume":"23","author":"Q Zhang","year":"1999","unstructured":"Zhang Q, Lee B, Korecka M, Li G, Weyland C, Eck S, et al. Differences in phosphorylation of the IL-2R associated JAK\/STAT proteins between HTLV-I(+), IL-2-independent and IL-2-dependent cell lines and uncultured leukemic cells from patients with adult T-cell lymphoma\/leukemia. Leuk Res. 1999;23:373\u201384.","journal-title":"Leuk Res"},{"key":"653_CR37","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0145-2126(03)00158-9","volume":"28","author":"J Cheng","year":"2004","unstructured":"Cheng J, Zhang D, Zhou C, Marasco WA. Down-regulation of SHP1 and up-regulation of negative regulators of JAK\/STAT signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral blood CD4+ T-cells. Leuk Res. 2004;28:71\u201382.","journal-title":"Leuk Res"},{"key":"653_CR38","doi-asserted-by":"crossref","first-page":"3716","DOI":"10.1158\/1078-0432.CCR-07-4839","volume":"14","author":"EG Jeong","year":"2008","unstructured":"Jeong EG, Kim MS, Nam HK, Min CK, Lee S, Chung YJ, et al. Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers. Clin Cancer Res. 2008;14:3716\u201321.","journal-title":"Clin Cancer Res"},{"key":"653_CR39","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/j.1365-2141.2008.07081.x","volume":"141","author":"T Sato","year":"2008","unstructured":"Sato T, Toki T, Kanezaki R, Xu G, Terui K, Kanegane H, et al. Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndrome. Br J Haematol. 2008;141:681\u20138.","journal-title":"Br J Haematol"},{"key":"653_CR40","first-page":"3770","volume":"61","author":"K Tsukasaki","year":"2001","unstructured":"Tsukasaki K, Miller CW, Kubota T, Takeuchi S, Fujimoto T, Ikeda S, et al. Tumor necrosis factor alpha polymorphism associated with increased susceptibility to development of adult T-cell leukemia\/lymphoma in human T-lymphotropic virus type 1 carriers. Cancer Res. 2001;61:3770\u20134.","journal-title":"Cancer Res"},{"key":"653_CR41","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1189\/jlb.0407198","volume":"83","author":"L Farre","year":"2008","unstructured":"Farre L, Bittencourt AL, Silva-Santos G, Almeida A, Silva AC, Decanine D, et al. Fas 670 promoter polymorphism is associated to susceptibility, clinical presentation, and survival in adult T cell leukemia. J Leukoc Biol. 2008;83:220\u20132.","journal-title":"J Leukoc Biol"}],"container-title":["International Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-010-0653-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12185-010-0653-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-010-0653-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T04:15:16Z","timestamp":1591762516000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12185-010-0653-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,10]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["653"],"URL":"https:\/\/doi.org\/10.1007\/s12185-010-0653-2","relation":{},"ISSN":["0925-5710","1865-3774"],"issn-type":[{"value":"0925-5710","type":"print"},{"value":"1865-3774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,10]]}}}