{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T01:17:45Z","timestamp":1780449465337,"version":"3.54.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2013,3,22]],"date-time":"2013-03-22T00:00:00Z","timestamp":1363910400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Hematol"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1007\/s12185-013-1316-x","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T02:10:56Z","timestamp":1363831856000},"page":"520-524","source":"Crossref","is-referenced-by-count":32,"title":["Successful treatment by azacitidine therapy of intestinal Beh\u00e7et\u2019s disease associated with myelodysplastic syndrome"],"prefix":"10.1007","volume":"97","author":[{"given":"Hiroaki","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emi","family":"Tougasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chika","family":"Kawajiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shio","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikako","family":"Ohwada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiko","family":"Sakaida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiaki","family":"Nakaseko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,3,22]]},"reference":[{"key":"1316_CR1","first-page":"88","volume-title":"WHO classification of tumours of haematopoietic and lymphoid tissues","author":"RD Brunning","year":"2008","unstructured":"Brunning RD, Germing U, Le Beau MM, Porwit A, Baumann I, Vardiman JW, Hellstrom-Lindberg E. Myelodysplastic syndromes\/neoplasms, overview. In: Swerdlow SH, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, editors. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press; 2008. p. 88\u201393."},{"issue":"5","key":"1316_CR2","first-page":"721","volume":"18","author":"M Castro","year":"1991","unstructured":"Castro M, Conn DL, Su WP, Garton JP. Rheumatic manifestations in myelodysplastic syndromes. J Rheumatol. 1991;18(5):721\u20137.","journal-title":"J Rheumatol"},{"issue":"5\u20136","key":"1316_CR3","doi-asserted-by":"crossref","first-page":"483","DOI":"10.3109\/10428199709055585","volume":"24","author":"H Enright","year":"1997","unstructured":"Enright H, Miller W. Autoimmune phenomena in patients with myelodysplastic syndromes. Leuk Lymphoma. 1997;24(5\u20136):483\u20139.","journal-title":"Leuk Lymphoma"},{"issue":"8697","key":"1316_CR4","first-page":"1078","volume":"335","author":"International Study Group for Behcet\u2019s Disease","year":"1990","unstructured":"International Study Group for Behcet\u2019s Disease. Criteria for diagnosis of Behcet\u2019s disease. Lancet. 1990;335(8697):1078\u201380.","journal-title":"Lancet"},{"issue":"17","key":"1316_CR5","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1056\/NEJM199910213411707","volume":"341","author":"T Sakane","year":"1999","unstructured":"Sakane T, Takeno M, Suzuki N, Inaba G. Behcet\u2019s disease. N Engl J Med. 1999;341(17):1284\u201391.","journal-title":"N Engl J Med"},{"issue":"4","key":"1316_CR6","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.survophthal.2005.04.009","volume":"50","author":"C Evereklioglu","year":"2005","unstructured":"Evereklioglu C. Current concepts in the etiology and treatment of Behcet disease. Surv Ophthalmol. 2005;50(4):297\u2013350.","journal-title":"Surv Ophthalmol"},{"issue":"2","key":"1316_CR7","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1002\/(SICI)1097-0142(19970115)79:2<262::AID-CNCR9>3.0.CO;2-M","volume":"79","author":"E Ohno","year":"1997","unstructured":"Ohno E, Ohtsuka E, Watanabe K, Kohno T, Takeoka K, Saburi Y, et al. Behcet\u2019s disease associated with myelodysplastic syndromes. A case report and a review of the literature. Cancer. 1997;79(2):262\u20138.","journal-title":"Cancer"},{"issue":"1","key":"1316_CR8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF02231696","volume":"15","author":"K Yano","year":"1996","unstructured":"Yano K, Eguchi K, Migita K, Takashima H, Tamura M, Izumino K, et al. Behcet\u2019s disease complicated with myelodysplastic syndrome: a report of two cases and review of the literature. Clin Rheumatol. 1996;15(1):91\u20133.","journal-title":"Clin Rheumatol"},{"issue":"38","key":"1316_CR9","first-page":"416","volume":"48","author":"H Ogawa","year":"2001","unstructured":"Ogawa H, Kuroda T, Inada M, Yamamoto M, Enomoto H, Kishima Y, et al. Intestinal Behcet\u2019s disease associated with myelodysplastic syndrome with chromosomal trisomy 8\u2014a report of two cases and a review of the literature. Hepatogastroenterology. 2001;48(38):416\u201320.","journal-title":"Hepatogastroenterology"},{"issue":"1","key":"1316_CR10","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/BF02982607","volume":"77","author":"K Yamato","year":"2003","unstructured":"Yamato K. Successful cord blood stem cell transplantation for myelodysplastic syndrome with Behcet disease. Int J Hematol. 2003;77(1):82\u20135.","journal-title":"Int J Hematol"},{"issue":"7","key":"1316_CR11","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1007\/s00277-003-0819-6","volume":"83","author":"A Tomonari","year":"2004","unstructured":"Tomonari A, Tojo A, Takahashi T, Iseki T, Ooi J, Takahashi S, et al. Resolution of Behcet\u2019s disease after HLA-mismatched unrelated cord blood transplantation for myelodysplastic syndrome. Ann Hematol. 2004;83(7):464\u20136.","journal-title":"Ann Hematol"},{"issue":"5 Suppl 42","key":"1316_CR12","first-page":"S115","volume":"24","author":"Y Tada","year":"2006","unstructured":"Tada Y, Koarada S, Haruta Y, Mitamura M, Ohta A, Nagasawa K. The association of Behcet\u2019s disease with myelodysplastic syndrome in Japan: a review of the literature. Clin Exp Rheumatol. 2006;24(5 Suppl 42):S115\u20139.","journal-title":"Clin Exp Rheumatol"},{"issue":"22","key":"1316_CR13","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.2169\/internalmedicine.45.1718","volume":"45","author":"H Kawabata","year":"2006","unstructured":"Kawabata H, Sawaki T, Kawanami T, Shimoyama K, Karasawa H, Fukushima T, et al. Myelodysplastic syndrome complicated with inflammatory intestinal ulcers: significance of trisomy 8. Intern Med. 2006;45(22):1309\u201314.","journal-title":"Intern Med"},{"issue":"20","key":"1316_CR14","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.2169\/internalmedicine.46.0291","volume":"46","author":"A Nonami","year":"2007","unstructured":"Nonami A, Takenaka K, Sumida C, Aizawa K, Kamezaki K, Miyamoto T, et al. Successful treatment of myelodysplastic syndrome (MDS)-related intestinal Behcet\u2019s disease by up-front cord blood transplantation. Intern Med. 2007;46(20):1753\u20136.","journal-title":"Intern Med"},{"issue":"4","key":"1316_CR15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s10165-010-0291-9","volume":"20","author":"T Fujimura","year":"2010","unstructured":"Fujimura T, Yukawa N, Nakashima R, Imura Y, Kawabata D, Nojima T, et al. Periodic fever and erythema nodosum associated with MDS with trisomy 8: report of two cases and review of the literature. Mod Rheumatol. 2010;20(4):413\u20139.","journal-title":"Mod Rheumatol"},{"issue":"4 Suppl 38","key":"1316_CR16","first-page":"S108","volume":"23","author":"A Kuttikat","year":"2005","unstructured":"Kuttikat A, Haskard D, Chakravarty K. Behcet\u2019s disease associated with trisomy 8 in a male Caucasian patient from Great Britain\u2014a case report. Clin Exp Rheumatol. 2005;23(4 Suppl 38):S108\u20139.","journal-title":"Clin Exp Rheumatol"},{"issue":"3","key":"1316_CR17","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/pbc.21075","volume":"50","author":"JV Thachil","year":"2008","unstructured":"Thachil JV, Salim R, Field A, Moots R, Bolton-Maggs P. Myelodysplastic syndrome with trisomy 8 associated with Behcet syndrome: an immunologic link to a karyotypic abnormality. Pediatr Blood Cancer. 2008;50(3):649\u201351.","journal-title":"Pediatr Blood Cancer"},{"issue":"4","key":"1316_CR18","first-page":"706","volume":"26","author":"P Mora","year":"2008","unstructured":"Mora P, Avellis FO, Zavota L, Orsoni JG. Behcet\u2019s disease associated with trisomy 8 in a young Italian girl\u2014a case report. Clin Exp Rheumatol. 2008;26(4):706.","journal-title":"Clin Exp Rheumatol"},{"issue":"1","key":"1316_CR19","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s12185-011-0998-1","volume":"95","author":"Y Miyazaki","year":"2012","unstructured":"Miyazaki Y. Guest editorial: introduction of Progress in Hematology in this issue. Int J Hematol. 2012;95(1):5\u20137.","journal-title":"Int J Hematol"},{"key":"1316_CR20","doi-asserted-by":"crossref","unstructured":"Yamazaki J, Issa JP. Epigenetic aspects of MDS and its molecular targeted therapy. Int J Hematol. 2013;97(2):175\u201382.","DOI":"10.1007\/s12185-012-1197-4"},{"issue":"1","key":"1316_CR21","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s12185-011-0987-4","volume":"95","author":"MC Ornstein","year":"2012","unstructured":"Ornstein MC, Sekeres MA. Combination strategies in myelodysplastic syndromes. Int J Hematol. 2012;95(1):26\u201333.","journal-title":"Int J Hematol"},{"issue":"3","key":"1316_CR22","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S1470-2045(09)70003-8","volume":"10","author":"P Fenaux","year":"2009","unstructured":"Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A, et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol. 2009;10(3):223\u201332.","journal-title":"Lancet Oncol."},{"issue":"9293","key":"1316_CR23","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1016\/S0140-6736(01)06677-6","volume":"358","author":"S Munoz-Fernandez","year":"2001","unstructured":"Munoz-Fernandez S, Hidalgo V, Fernandez-Melon J, Schlincker A, Martin-Mola E. Effect of infliximab on threatening panuveitis in Behcet\u2019s disease. Lancet. 2001;358(9293):1644.","journal-title":"Lancet"},{"issue":"5","key":"1316_CR24","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1136\/gut.49.5.725","volume":"49","author":"SP Travis","year":"2001","unstructured":"Travis SP, Czajkowski M, McGovern DP, Watson RG, Bell AL. Treatment of intestinal Behcet\u2019s syndrome with chimeric tumour necrosis factor alpha antibody. Gut. 2001;49(5):725\u20138.","journal-title":"Gut"},{"issue":"4","key":"1316_CR25","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/rheumatology\/40.4.473","volume":"40","author":"LP Robertson","year":"2001","unstructured":"Robertson LP, Hickling P. Treatment of recalcitrant orogenital ulceration of Behcet\u2019s syndrome with infliximab. Rheumatology (Oxford). 2001;40(4):473\u20134.","journal-title":"Rheumatology (Oxford)"},{"issue":"13","key":"1316_CR26","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1182\/blood-2004-01-0103","volume":"104","author":"G Chen","year":"2004","unstructured":"Chen G, Zeng W, Miyazato A, Billings E, Maciejewski JP, Kajigaya S, et al. Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities. Blood. 2004;104(13):4210\u20138.","journal-title":"Blood"},{"issue":"1","key":"1316_CR27","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1182\/blood-2009-03-210393","volume":"115","author":"LI Sanchez-Abarca","year":"2010","unstructured":"Sanchez-Abarca LI, Gutierrez-Cosio S, Santamaria C, Caballero-Velazquez T, Blanco B, Herrero-Sanchez C, et al. Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting. Blood. 2010;115(1):107\u201321.","journal-title":"Blood"},{"issue":"3","key":"1316_CR28","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1634\/theoncologist.10-3-176","volume":"10","author":"E Kaminskas","year":"2005","unstructured":"Kaminskas E, Farrell AT, Wang YC, Sridhara R, Pazdur R. FDA drug approval summary: azacitidine (5-azacytidine, Vidaza) for injectable suspension. Oncologist. 2005;10(3):176\u201382.","journal-title":"Oncologist."}],"container-title":["International Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-013-1316-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12185-013-1316-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-013-1316-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T01:11:11Z","timestamp":1559437871000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12185-013-1316-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,22]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["1316"],"URL":"https:\/\/doi.org\/10.1007\/s12185-013-1316-x","relation":{},"ISSN":["0925-5710","1865-3774"],"issn-type":[{"value":"0925-5710","type":"print"},{"value":"1865-3774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,22]]}}}