{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T03:55:35Z","timestamp":1763178935917},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T00:00:00Z","timestamp":1458000000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Hematol"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1007\/s12185-016-1978-2","type":"journal-article","created":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T15:38:48Z","timestamp":1458315528000},"page":"718-723","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Successful treatment of TAFRO syndrome, a variant type of multicentric Castleman disease with thrombotic microangiopathy, with anti-IL-6 receptor antibody and steroids"],"prefix":"10.1007","volume":"103","author":[{"given":"Shiho","family":"Fujiwara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Mochinaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotomo","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Ohshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Uchiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Mikami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Hata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Okuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Mitsuya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kisato","family":"Nosaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,3,15]]},"reference":[{"key":"1978_CR1","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1056\/NEJM195406102502308","volume":"250","author":"B Castleman","year":"1954","unstructured":"Castleman B, Towne VW. Case records of the Massachusetts General Hospital: case No. 40231. N Engl J Med. 1954;250:1001\u20135.","journal-title":"N Engl J Med"},{"key":"1978_CR2","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/1097-0142(197203)29:3<670::AID-CNCR2820290321>3.0.CO;2-#","volume":"29","author":"AR Keller","year":"1972","unstructured":"Keller AR, Hochholzer L, Castleman B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer. 1972;29:670\u201383.","journal-title":"Cancer"},{"key":"1978_CR3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1097\/PAP.0b013e3181a9d4d3","volume":"16","author":"DM Cronin","year":"2009","unstructured":"Cronin DM, Warnke RA. Castleman disease: an update on classification and the spectrum of associated lesions. Adv Anat Pathol. 2009;16:236\u201346.","journal-title":"Adv Anat Pathol."},{"key":"1978_CR4","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1182\/blood-2013-12-545087","volume":"123","author":"DC Fajgenbaum","year":"2014","unstructured":"Fajgenbaum DC, van Rhee F, Nabel CS. HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy. Blood. 2014;123:2924\u201333.","journal-title":"Blood"},{"key":"1978_CR5","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1634\/theoncologist.2010-0212","volume":"16","author":"HE El-Osta","year":"2011","unstructured":"El-Osta HE, Kurzrock R. Castleman\u2019s disease: from basic mechanisms to molecular therapeutics. Oncologist. 2011;16:497\u2013511.","journal-title":"Oncologist"},{"key":"1978_CR6","first-page":"320","volume":"51","author":"K Takai","year":"2010","unstructured":"Takai K, Nikkuni K, Shibuya H, Hashidate H. Thrombocytopenia with mild bone marrow fibrosis accompanied by fever, pleural effision, ascites, and hepatosplenomegaly. Rinsho Ketsueki. 2010;51:320\u20135 (in Japanese).","journal-title":"Rinsho Ketsueki"},{"key":"1978_CR7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3960\/jslrt.53.57","volume":"53","author":"H Kawabata","year":"2013","unstructured":"Kawabata H, Takai K, Kojima M, Nakamura N, Aoki S, Nakamura S, et al. Castleman-Kojima disease (TAFRO syndrome): a novel systemic inflammatory disease characterized by a constellation of symptoms, namely, thrombocytopenia, ascites (anasarca), microcytic anemia, myelofibrosis, renal dysfunction, and organomegaly: a status report and summary of Fukushima (6 June, 2012) and Nagoya meetings (22 September, 2012). J Clin Exp Hematop. 2013;53:57\u201361.","journal-title":"J Clin Exp Hematop"},{"key":"1978_CR8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/1471-2431-14-139","volume":"14","author":"I Kubokawa","year":"2014","unstructured":"Kubokawa I, Yacjie A, Hayakawa A, Hirase S, Yamamoto N, Mori T, et al. The first report of adolescent TAFRO syndrome, a unique clinicopathologic variant of multicentric Castleman\u2019s disease. BMC Pediatr. 2014;14:139.","journal-title":"BMC Pediatr"},{"key":"1978_CR9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/ajcp\/94.1.101","volume":"94","author":"PA Carrington","year":"1990","unstructured":"Carrington PA, Anderson H, Harris M, Walsh SE, Houghton JB, Morgenstern GR. Autoimmune cytopenias in Castleman\u2019s disease. Am J Clin Pathol. 1990;94:101\u20134.","journal-title":"Am J Clin Pathol"},{"key":"1978_CR10","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3109\/03009749709065725","volume":"26","author":"K Higashi","year":"1997","unstructured":"Higashi K, Matsuki Y, Hidaka T, Aida S, Suzuki K, Nakamura H. Primary Sjogren\u2019s syndrome associated with hyaline-vascular type of Castleman\u2019s disease and autoimmune idiopathic thrombocytopenia. Scand J Rheumatol. 1997;26:482\u20134.","journal-title":"Scand J Rheumatol"},{"key":"1978_CR11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/mpo.2950180216","volume":"18","author":"JH Marsh","year":"1990","unstructured":"Marsh JH, Colbourn DS, Donovan V, Staszewski H. Systemic Castleman\u2019s disease in association with Evan\u2019s syndrome and vitiligo. Med Pediatr Oncol. 1990;18:169\u201372.","journal-title":"Med Pediatr Oncol"},{"key":"1978_CR12","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1136\/jcp.2009.071415","volume":"63","author":"H Gakiopoulou","year":"2010","unstructured":"Gakiopoulou H, Korkolopoulou P, Paraskevakou H, Marinaki S, Voulgarelis M, Stofas A, et al. Membranoproliferative glomerulonephritis in the setting of multicentric angiofollicular lymph node hyperplasia (Castleman\u2019s disease) complicated by Evan\u2019s syndrome. J Clin Pathol. 2010;63:552\u20134.","journal-title":"J Clin Pathol"},{"key":"1978_CR13","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/MBC.0000000000000065","volume":"25","author":"M Stockschlaeder","year":"2014","unstructured":"Stockschlaeder M, Schneppenheim R, Budde U. Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis. Blood Coagul Fibrinolysis. 2014;25:206\u201316.","journal-title":"Blood Coagul Fibrinolysis"},{"key":"1978_CR14","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.thromres.2013.07.027","volume":"132","author":"S Rangarajan","year":"2013","unstructured":"Rangarajan S, Kessler C, Aledort L. The clinical implications of ADAMTS13 function: the perspectives of haemostaseologists. Thromb Res. 2013;132:403\u20137.","journal-title":"Thromb Res"},{"key":"1978_CR15","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1182\/blood-2004-01-0107","volume":"104","author":"A Bernardo","year":"2004","unstructured":"Bernardo A, Ball C, Nolasco L, Moake JF, Dong JF. Effects of inflammatory cytokines on the release and cleavage of the endothelial cell-derived ultralarge von Willebrand factor multimers under flow. Blood. 2004;104:100\u20136.","journal-title":"Blood"},{"key":"1978_CR16","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.4049\/jimmunol.170.6.3369","volume":"170","author":"A Li","year":"2003","unstructured":"Li A, Dubey S, Varney ML, Dave BJ, Singh RK. IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol. 2003;170:3369\u201376.","journal-title":"J Immunol"},{"key":"1978_CR17","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1111\/j.1538-7836.2008.02989.x","volume":"6","author":"WJ Cao","year":"2008","unstructured":"Cao WJ, Niiya M, Zheng XW, Shang DZ, Zheng XL. Inflammatory cytokines inhibit ADAMTS13 synthesis in hepatic stellate cells and endothelial cells. J Thromb Haemost. 2008;6:1233\u20135.","journal-title":"J Thromb Haemost"},{"key":"1978_CR18","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1182\/blood.V74.4.1360.1360","volume":"74","author":"K Yoshizaki","year":"1989","unstructured":"Yoshizaki K, Matsuda T, Nishimoto N, Kuritani T, Taeho L, Aozasa K, et al. Pathogenic significance of interleukin-6 (IL-6\/BSF-2) in Castleman\u2019s disease. Blood. 1989;74:1360\u20137.","journal-title":"Blood"},{"key":"1978_CR19","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.2169\/internalmedicine.52.9482","volume":"52","author":"H Kawabata","year":"2013","unstructured":"Kawabata H, Kotani S, Matsumura Y, Kondo T, Katsurada T, Haga H, et al. Successful treatment of a patient with multicentric Castleman\u2019s disease who presented with thrombocytopenia, ascites, renal failure and myelofibrosis using tocilizumab, an anti-interleukin-6 receptor antibody. Intern Med. 2013;52:1503\u20137.","journal-title":"Intern Med"},{"key":"1978_CR20","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/2162-3619-4-3","volume":"4","author":"S Tedesco","year":"2015","unstructured":"Tedesco S, Postacchini L, Manfredi L, Goteri G, Luchetti MM, Festa A, et al. Successful treatment of a Caucasian case of multifocal Castleman\u2019s disease with TAFRO sydrome with a pathophysiology targeted therapy\u2014a case report. Exp Hematol Oncol. 2015;4:3.","journal-title":"Exp Hematol Oncol"}],"container-title":["International Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-016-1978-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12185-016-1978-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-016-1978-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T09:36:40Z","timestamp":1600335400000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12185-016-1978-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,15]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["1978"],"URL":"https:\/\/doi.org\/10.1007\/s12185-016-1978-2","relation":{},"ISSN":["0925-5710","1865-3774"],"issn-type":[{"value":"0925-5710","type":"print"},{"value":"1865-3774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,15]]}}}