{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:11:18Z","timestamp":1763017878741},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,4,2]],"date-time":"2018-04-02T00:00:00Z","timestamp":1522627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,4,2]],"date-time":"2018-04-02T00:00:00Z","timestamp":1522627200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Hematol"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1007\/s12185-018-2453-z","type":"journal-article","created":{"date-parts":[[2018,4,2]],"date-time":"2018-04-02T10:45:56Z","timestamp":1522665956000},"page":"145-150","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A discrepancy between prothrombin time and Normotest (Hepaplastintest) results is useful for diagnosis of acquired factor V inhibitors"],"prefix":"10.1007","volume":"108","author":[{"given":"Yasuko","family":"Kadohira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoe","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eriko","family":"Morishita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidesaku","family":"Asakura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akitada","family":"Ichinose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,4,2]]},"reference":[{"key":"2453_CR1","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s11239-010-0529-6","volume":"314","author":"M Franchini","year":"2011","unstructured":"Franchini M, Lippi G. Acquired factor V inhibitors: a systematic review. J Thromb Thrombolysis. 2011;314:449\u201357.","journal-title":"J Thromb Thrombolysis"},{"key":"2453_CR2","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1097\/MBC.0000000000000581","volume":"28","author":"X Wang","year":"2017","unstructured":"Wang X, Qin X, Yu Y, Wang R, Liu X, Ji M, et al. Acquired factor V deficiency in a patient with a urinary tract infection presenting with haematuria followed by multiple haemorrhages with an extremely low level of factor V inhibitor: a case report and review of the literature. Blood Coagul Fibrinolysis. 2017;28:334\u201341.","journal-title":"Blood Coagul Fibrinolysis"},{"key":"2453_CR3","doi-asserted-by":"publisher","first-page":"140","DOI":"10.2491\/jjsth.19.140","volume":"19","author":"I Tanaka","year":"2008","unstructured":"Tanaka I, Amano K, Taki M, Oka T, Sakai M, Shirahata A, et al. A 3-year consecutive survey on current status of acquired inhibitors against coagulation factors in Japan\u2014analysis of prognostic factors. Jpn J Thromb Hemost. 2008;19:140\u201353.","journal-title":"Jpn J Thromb Hemost"},{"key":"2453_CR4","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1007\/s12185-017-2210-8","volume":"106","author":"Y Ogawa","year":"2017","unstructured":"Ogawa Y, Yanagisawa K, Uchiumi H, Ishizaki T, Mitsui T, Gouda F, et al. Clinical characteristics and outcomes of acquired hemophilia A: experience at a single center in Japan. Int J Hematol. 2017;106:82\u20139.","journal-title":"Int J Hematol"},{"key":"2453_CR5","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1046\/j.1537-2995.2002.00011.x","volume":"42","author":"MB Streiff","year":"2002","unstructured":"Streiff MB, Ness PM. Acquired FV inhibitors: a needless iatrogenic complication of bovine thrombin exposure. Transfusion. 2002;42:18\u201326.","journal-title":"Transfusion"},{"key":"2453_CR6","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1160\/TH08-11-0767","volume":"101","author":"AL Ang","year":"2009","unstructured":"Ang AL, Kuperan P, Ng CH, Ng HJ. Acquired factor V inhibitor. A problem-based systematic review. Thromb Haemost. 2009;101:852\u20139.","journal-title":"Thromb Haemost."},{"key":"2453_CR7","first-page":"14","volume":"25","author":"PA Owren","year":"1969","unstructured":"Owren PA, Standi OK. Normotest. Farmakotherapi. 1969;25:14.","journal-title":"Farmakotherapi."},{"key":"2453_CR8","doi-asserted-by":"publisher","first-page":"111","DOI":"10.2491\/jjsth1970.7.111","volume":"7","author":"H Tsukada","year":"1976","unstructured":"Tsukada H, Shimoda T, Matsuo N, Hiraishi A, Shimoyama C, Arai H, et al. Study on Normotest (Hepaplastin test). Blood Vessel. 1976;7:111\u20138.","journal-title":"Blood Vessel."},{"key":"2453_CR9","doi-asserted-by":"publisher","first-page":"320","DOI":"10.2491\/jjsth1970.8.320","volume":"8","author":"T Takeuchi","year":"1977","unstructured":"Takeuchi T, Ueno T, Arai H, Maekawa T, Tsukada H. Studies of Normotest (Hepaplastin test) on control of anticoagulant therapy. Blood Vessel. 1977;8:320\u20135.","journal-title":"Blood Vessel."},{"key":"2453_CR10","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1179\/1607845412Y.0000000072","volume":"18","author":"M Ashizawa","year":"2013","unstructured":"Ashizawa M, Kimura S, Wada H, Sakamoto K, Sato M, Terasako K, et al. Acquired factor V inhibitor associated with life-threatening bleeding and a mixing test result that indicated coagulation factor deficiency. Hematology. 2013;18:300\u20134.","journal-title":"Hematology."},{"key":"2453_CR11","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1172\/JCI112318","volume":"77","author":"ME Nesheim","year":"1986","unstructured":"Nesheim ME, Nichols WL, Cole TL, Houston JG, Schenk RB, Mann KG, et al. Isolation and study of an acquired inhibitor of human coagulation factor V. J Clin Investig. 1986;77:405\u201315.","journal-title":"J Clin Investig."},{"key":"2453_CR12","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1182\/blood.V56.5.835.835","volume":"56","author":"J Chediak","year":"1980","unstructured":"Chediak J, Ashenhurst JB, Garlick I, Desser RK. Successful management of bleeding in a patient with factor V inhibitor by platelet transfusions. Blood. 1980;56:835\u201341.","journal-title":"Blood"},{"key":"2453_CR13","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1002\/ajh.21056","volume":"83","author":"A Lebrun","year":"2008","unstructured":"Lebrun A, Leroy-Matheron C, Arlet JB, Bartolucci P, Michel M. Successful treatment with rituximab in a patient with an acquired factor V inhibitor. Am J Hematol. 2008;83:163\u20134.","journal-title":"Am J Hematol"},{"key":"2453_CR14","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s12185-015-1742-z","volume":"101","author":"ES Ma","year":"2015","unstructured":"Ma ES, Liang RH, Chu KM, Lau GK. Complete response of acquired FV inhibitor to rituximab. Int J Hematol. 2015;101:421\u20132.","journal-title":"Int J Hematol"}],"container-title":["International Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12185-018-2453-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-018-2453-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-018-2453-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T12:15:09Z","timestamp":1659096909000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12185-018-2453-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,2]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["2453"],"URL":"https:\/\/doi.org\/10.1007\/s12185-018-2453-z","relation":{},"ISSN":["0925-5710","1865-3774"],"issn-type":[{"value":"0925-5710","type":"print"},{"value":"1865-3774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,2]]},"assertion":[{"value":"18 January 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 March 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no conflicts of interest in association with the present study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}