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R.S. received honoraria from Kyowa Hakko Kirin and Chugai Pharmaceutical. The other authors declare no competing financial interests. M.I. Dr. Iida received donation to the endowed chair from Kyowa Kirin Co., Ltd., JCR Pharmaceuticals Co., Ltd., Clinigen K.K., Astellas Pharma Inc., Genzyme Japan K.K., CHUGAI PHARMACEUTICAL CO., LTD., Janssen Pharmaceutical K.K., Sanofi K.K., Otsuka Pharmaceutical Co., Ltd. K.N. received Grants from Kyowa Kirin and from Chugai Pharma. K.M. received honoraria from Bristol Myers, Novartis, Pfizer, Astellas, Takeda, Otsuka, Celgene, Dainippon-Sumitomo, Kyowa-Hakko Kirin, Chugai, MSD, and Alexon. S.O. received Grants from Asahi Kasei Pharma, Astellas, Eisai, Otsuka, Ono, Kyowa Kirin, Sanofi, Shionogi, Daiichi Sankyo, Takeda, Dainihon Sumitomo, Chugai, Teijin Pharma, Novartis, Mochida, JCR Pharma, and Pfizer, and received honoraria from Astellas, Eisai, Otsuka, Ono, Kyowa Kirin, Sanofi, Daiichi Sankyo, Takeda, Chugai, Nihon Shinyaku, Novartis, BMS, Mochida, JCR Pharma, and Pfizer. M.H. received Grants from Kyowa-Kirin, Chugai, Otsuka, Astellas, Takeda, Taiho, Teijin, MSD, Sumitomo Dainippon, Pfizer, Eisai, Japan Blood Products Organization, and Nihon Pharmaceutical, and received honoraria from Kyowa-Kirin, Chugai, Otsuka, Astellas, Takeda, MSD, Sumitomo Dainippon, Pfizer, Bristol-Myers Squibb, Daiichisankyo, Jansenn, Celgene, Mochida, Ono, Sanofi, Nippon Shinyaku, Mundi Pharma, and Alexion. The other authors declare no competing financial interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}