{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T16:44:53Z","timestamp":1788367493935,"version":"build-2803163510"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:00:00Z","timestamp":1656288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:00:00Z","timestamp":1656288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Hematol"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1007\/s12185-022-03400-1","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T18:58:36Z","timestamp":1656356316000},"page":"807-811","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Septic shock caused by Capnocytophaga canimorsus in a patient with heterozygous Pelger-Hu\u00ebt anomaly"],"prefix":"10.1007","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2511-9799","authenticated-orcid":false,"given":"Sara","family":"Franco-Serrano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neus","family":"Amer-Salas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmina","family":"Nieto-Pi\u00f1ar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"V\u00e1zquez-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"Forteza-Ca\u00f1ellas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Rialp-Cervera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan J.","family":"Bargay-Lleonart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,6,27]]},"reference":[{"issue":"7","key":"3400_CR1","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1007\/s10096-015-2360-7","volume":"34","author":"T Butler","year":"2015","unstructured":"Butler T. Capnocytophaga canimorsus: an emerging cause of sepsis, meningitis, and post-splenectomy infection after dog bites. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol. 2015;34(7):1271\u201380.","journal-title":"Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol."},{"issue":"6","key":"3400_CR2","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1016\/j.jemermed.2018.01.042","volume":"54","author":"N Bertin","year":"2018","unstructured":"Bertin N, Brosolo G, Pistola F, Pelizzo F, Marini C, Pertoldi F, et al. Capnocytophaga canimorsus: an emerging pathogen in\u00a0immunocompetent patients-experience from an\u00a0emergency department. J Emerg Med. 2018;54(6):871\u20135.","journal-title":"J Emerg Med"},{"issue":"10","key":"3400_CR3","doi-asserted-by":"publisher","first-page":"2197","DOI":"10.1128\/AAC.36.10.2197","volume":"36","author":"DL Roscoe","year":"1992","unstructured":"Roscoe DL, Zemcov SJ, Thornber D, Wise R, Clarke AM. Antimicrobial susceptibilities and beta-lactamase characterization of Capnocytophaga species. Antimicrob Agents Chemother. 1992;36(10):2197\u2013200.","journal-title":"Antimicrob Agents Chemother"},{"key":"3400_CR4","doi-asserted-by":"publisher","first-page":"22919","DOI":"10.1038\/srep22919","volume":"6","author":"S Zangenah","year":"2016","unstructured":"Zangenah S, Abbasi N, Andersson AF, Bergman P. Whole genome sequencing identifies a novel species of the genus Capnocytophaga isolated from dog and cat bite wounds in humans. Sci Rep. 2016;6:22919.","journal-title":"Sci Rep"},{"issue":"8","key":"3400_CR5","first-page":"e48","volume":"4","author":"F Renzi","year":"2015","unstructured":"Renzi F, Dol M, Raymackers A, Manfredi P, Cornelis GR. Only a subset of C. canimorsus strains is dangerous for humans. Emerg Microbes Infect. 2015;4(8):e48.","journal-title":"Emerg Microbes Infect"},{"issue":"1","key":"3400_CR6","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.jhsa.2015.10.011","volume":"41","author":"NJ Dedy","year":"2016","unstructured":"Dedy NJ, Coghill S, Chandrashekar NKS, Bindra RR. Capnocytophaga canimorsus sepsis following a minor dog bite to the finger: case report. J Hand Surg. 2016;41(1):81\u20134.","journal-title":"J Hand Surg"},{"issue":"4","key":"3400_CR7","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1093\/ajcp\/65.4.564","volume":"65","author":"RA Bobo","year":"1976","unstructured":"Bobo RA, Newton EJ. A previously undescribed gram-negative bacillus causing septicemia and meningitis. Am J Clin Pathol. 1976;65(4):564\u20139.","journal-title":"Am J Clin Pathol"},{"issue":"12","key":"3400_CR8","doi-asserted-by":"publisher","first-page":"2195","DOI":"10.3201\/eid2412.172060","volume":"24","author":"E Hess","year":"2018","unstructured":"Hess E, Renzi F, Karhunen P, Dol M, Lef\u00e8vre A, Antikainen J, et al. Capnocytophaga canimorsus Capsular Serovar and Disease Severity, Helsinki Hospital District, Finland, 2000\u20132017. Emerg Infect Dis. 2018;24(12):2195\u2013201.","journal-title":"Emerg Infect Dis"},{"issue":"1","key":"3400_CR9","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1093\/clinids\/23.1.71","volume":"23","author":"C Pers","year":"1996","unstructured":"Pers C, Gahrn-Hansen B, Frederiksen W. Capnocytophaga canimorsus septicemia in Denmark, 1982\u20131995: review of 39 cases. Clin Infect Dis Off Publ Infect Dis Soc Am. 1996;23(1):71\u20135.","journal-title":"Clin Infect Dis Off Publ Infect Dis Soc Am"},{"issue":"6","key":"3400_CR10","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1111\/zph.12248","volume":"63","author":"A van Samkar","year":"2016","unstructured":"van Samkar A, Brouwer MC, Schultsz C, van der Ende A, van de Beek D. Capnocytophaga canimorsus Meningitis: three cases and a review of the literature. Zoonoses Public Health. 2016;63(6):442\u20138.","journal-title":"Zoonoses Public Health"},{"issue":"10","key":"3400_CR11","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1111\/aas.12752","volume":"60","author":"J H\u00e4stbacka","year":"2016","unstructured":"H\u00e4stbacka J, Hynninen M, Kolho E. Capnocytophaga canimorsus bacteremia: clinical features and outcomes from a Helsinki ICU cohort. Acta Anaesthesiol Scand. 2016;60(10):1437\u201343.","journal-title":"Acta Anaesthesiol Scand"},{"issue":"21\u201322","key":"3400_CR12","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1016\/j.cca.2010.07.011","volume":"411","author":"LMS Dusse","year":"2010","unstructured":"Dusse LMS, Moreira AMB. Acquired Pelger-Hu\u00ebt: what does it really mean? Clin Chim Acta. 2010;411(21\u201322):1587\u201390.","journal-title":"Clin Chim Acta"},{"key":"3400_CR13","volume-title":"La Citolog\u00eda \u00f3ptica en el diagn\u00f3stico hematol\u00f3gico","author":"S Woessner","year":"2009","unstructured":"Woessner S, Florensa L, Sans-Sabrafen J. La Citolog\u00eda \u00f3ptica en el diagn\u00f3stico hematol\u00f3gico. Madrid: Acci\u00f3n M\u00e9dica; 2009."},{"issue":"2","key":"3400_CR14","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1309\/AJCPVFY95MAOBKRS","volume":"135","author":"E Wang","year":"2011","unstructured":"Wang E, Boswell E. Pseudo-Pelger-Hu\u00ebt anomaly induced by medications: a clinicopathologic study in comparison with myelodysplastic syndrome-related pseudo-Pelger-Hu\u00ebt anomaly. Am J Clin Pathol. 2011;135(2):291\u2013303.","journal-title":"Am J Clin Pathol"},{"issue":"3","key":"3400_CR15","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1309\/AJCP3G8MDUXYSCID","volume":"137","author":"R Colella","year":"2012","unstructured":"Colella R, Hollensead S. Understanding and recognizing the Pelger-Hu\u00ebt anomaly. Am J Clin Pathol. 2012;137(3):358\u201366.","journal-title":"Am J Clin Pathol"},{"issue":"3","key":"3400_CR16","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1182\/blood.V55.3.466.466","volume":"55","author":"CA Johnson","year":"1980","unstructured":"Johnson CA, Bass DA, Trillo AA, Snyder MS, DeChatelet LR. Functional and metabolic studies of polymorphonuclear leukocytes in the congenital Pelger-Huet anomaly. Blood. 1980;55(3):466\u20139.","journal-title":"Blood"},{"issue":"2","key":"3400_CR17","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/ajh.21320","volume":"84","author":"JM Cunningham","year":"2009","unstructured":"Cunningham JM, Patnaik MM. Historical perspective and clinical implications of the Pelger-H\u00fcet cell. Am J Hematol. 2009;84(2):116\u20139.","journal-title":"Am J Hematol"},{"key":"3400_CR18","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3181\/00379727-155-39743","volume":"155","author":"BH Park","year":"1977","unstructured":"Park BH, Dolen J. Defective chemotactic migration of polymorphonuclear leukocytes in Pelger-Hu\u00ebt anomaly. Proc Soc Exp Biol Med. 1977;155:51\u20135.","journal-title":"Proc Soc Exp Biol Med"},{"issue":"5","key":"3400_CR19","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S0213-005X(04)73097-9","volume":"22","author":"A Gonz\u00e1lez-Garc\u00eda","year":"2004","unstructured":"Gonz\u00e1lez-Garc\u00eda A, Ferreiro JJ, L\u00f3pez-Lopategui MC, Zabarte M. Septic shock with purpura fulminans due to Capnocytophaga canimorsus. Enferm Infecc Microbiol Clin. 2004;22(5):309\u201310.","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"2","key":"3400_CR20","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1136\/practneurol-2015-001166","volume":"16","author":"TMJ Beernink","year":"2016","unstructured":"Beernink TMJ, Wever PC, Hermans MHA, Bartholomeus MGT. Capnocytophaga canimorsus meningitis diagnosed by 16S rRNA PCR. Pract Neurol. 2016;16(2):136\u20138.","journal-title":"Pract Neurol"},{"issue":"7","key":"3400_CR21","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1111\/j.1699-0463.1993.tb00148.x","volume":"101","author":"G Pedersen","year":"1993","unstructured":"Pedersen G, Sch\u00f8nheyder HC, Nielsen LC. Capnocytophaga canimorsus bacteraemia demonstrated by a positive blood smear. A case report. APMIS Acta Pathol Microbiol Immunol Scand. 1993;101(7):572\u20134.","journal-title":"APMIS Acta Pathol Microbiol Immunol Scand."},{"issue":"2","key":"3400_CR22","doi-asserted-by":"publisher","first-page":"368","DOI":"10.4103\/0377-4929.81642","volume":"54","author":"S Chary","year":"2011","unstructured":"Chary S, Joshi M, Reddy S, Ryan C, Saddi V. Septicemia due to Capnocytophaga canimorsus following dog bite in an elderly male. Indian J Pathol Microbiol. 2011;54(2):368\u201370.","journal-title":"Indian J Pathol Microbiol"},{"issue":"6","key":"3400_CR23","doi-asserted-by":"publisher","first-page":"2262","DOI":"10.1128\/IAI.01324-08","volume":"77","author":"H Shin","year":"2009","unstructured":"Shin H, Mally M, Meyer S, Fiechter C, Paroz C, Zaehringer U, et al. Resistance of Capnocytophaga canimorsus to killing by human complement and polymorphonuclear leukocytes. Infect Immun. 2009;77(6):2262\u201371.","journal-title":"Infect Immun"},{"issue":"2","key":"3400_CR24","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1097\/PAF.0b013e3181dfc98b","volume":"31","author":"D Stiegler","year":"2010","unstructured":"Stiegler D, Gilbert JD, Warner MS, Byard RW. Fatal dog bite in the absence of significant trauma: Capnocytophaga canimorsus infection and unexpected death. Am J Forensic Med Pathol. 2010;31(2):198\u20139.","journal-title":"Am J Forensic Med Pathol"},{"issue":"5","key":"3400_CR25","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s15010-015-0740-7","volume":"43","author":"JD Cooper","year":"2015","unstructured":"Cooper JD, Dorion RP, Smith JL. A rare case of waterhouse-friderichsen syndrome caused by Capnocytophaga canimorsus in an immunocompetent patient. Infection. 2015;43(5):599\u2013602.","journal-title":"Infection"},{"issue":"3\u20134","key":"3400_CR26","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.vetmic.2009.01.040","volume":"140","author":"W Gaastra","year":"2010","unstructured":"Gaastra W, Lipman LJA. Capnocytophaga canimorsus. Vet Microbiol. 2010;140(3\u20134):339\u201346.","journal-title":"Vet Microbiol"},{"issue":"2","key":"3400_CR27","first-page":"312","volume":"17","author":"AP Van Dam","year":"2011","unstructured":"Van Dam AP, Jansz A. Capnocytophaga canimorsus infections in The Netherlands: a nationwide survey. Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis. 2011;17(2):312\u20135.","journal-title":"Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis"},{"key":"3400_CR28","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1186\/1756-0500-7-432","volume":"7","author":"O Hloch","year":"2014","unstructured":"Hloch O, Mokra D, Masopust J, Hasa J, Charvat J. Antibiotic treatment following a dog bite in an immunocompromized patient in order to prevent Capnocytophaga canimorsus infection: a case report. BMC Res Notes. 2014;7:432.","journal-title":"BMC Res Notes"}],"container-title":["International Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-022-03400-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12185-022-03400-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-022-03400-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T01:17:33Z","timestamp":1666574253000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12185-022-03400-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,27]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["3400"],"URL":"https:\/\/doi.org\/10.1007\/s12185-022-03400-1","relation":{},"ISSN":["0925-5710","1865-3774"],"issn-type":[{"value":"0925-5710","type":"print"},{"value":"1865-3774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,27]]},"assertion":[{"value":"14 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 June 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}