{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T14:11:58Z","timestamp":1771078318216,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T00:00:00Z","timestamp":1700265600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T00:00:00Z","timestamp":1700265600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Hematol"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1007\/s12185-023-03673-0","type":"journal-article","created":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T18:02:03Z","timestamp":1700330523000},"page":"80-87","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clonal hematopoiesis of a novel dic(18;20) clone following allogeneic hematopoietic stem cell transplantation"],"prefix":"10.1007","volume":"119","author":[{"given":"Makoto","family":"Ito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuaki","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Numata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiori","family":"Morikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuma","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyo","family":"Goto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Kohno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiko","family":"Imahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiko","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Sanada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Kiyoi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutaka","family":"Ozeki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,11,18]]},"reference":[{"key":"3673_CR1","doi-asserted-by":"publisher","first-page":"2488","DOI":"10.1056\/NEJMoa1408617","volume":"26","author":"S Jaiswal","year":"2014","unstructured":"Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, et al. Age-related clonal hematopoiesis associated with adverse outcomes. N Engl J Med. 2014;26:2488\u201398.","journal-title":"N Engl J Med"},{"key":"3673_CR2","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1038\/s41591-021-01411-9","volume":"27","author":"R Saiki","year":"2021","unstructured":"Saiki R, Momozawa Y, Nannya Y, Nakagawa MM, Ochi Y, Yoshizato T, et al. Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis. Nat Med. 2021;27:1239\u201349.","journal-title":"Nat Med"},{"issue":"2","key":"3673_CR3","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1200\/JCO.21.02286","volume":"40","author":"CJ Gibson","year":"2022","unstructured":"Gibson CJ, Kim HT, Zhao L, Murdock HM, Hambley B, Ogata A, et al. Donor clonal hematopoiesis and recipient outcomes after transplantation. J Clin Oncol. 2022;40(2):189\u2013201.","journal-title":"J Clin Oncol"},{"issue":"8","key":"3673_CR4","doi-asserted-by":"publisher","first-page":"662.e1","DOI":"10.1016\/j.jtct.2021.04.014","volume":"27","author":"LF Newell","year":"2021","unstructured":"Newell LF, Williams T, Liu J, Yu Y, Chen Y, Booth GC, et al. Engrafted donor-derived clonal hematopoiesis after allogenic hematopoietic cell transplantation is associated with chronic graft-versus-host disease requiring immunosuppressive therapy, but no adverse impact on overall survival or relapse. Transplant Cell Ther. 2021;27(8):662.e1-662.e9.","journal-title":"Transplant Cell Ther"},{"key":"3673_CR5","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1038\/s41375-021-01312-3","volume":"36","author":"B Oran","year":"2022","unstructured":"Oran B, Champlin RE, Wang F, Tanaka T, Saliba RM, Al-Atrash G, et al. Donor clonal hematopoiesis increases risk of acute graft versus host disease after matched sibling transplantation. Leukemia. 2022;36:257\u201362.","journal-title":"Leukemia"},{"issue":"1","key":"3673_CR6","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1038\/s41467-022-29304-6","volume":"13","author":"N Kawashima","year":"2022","unstructured":"Kawashima N, Ishikawa Y, Kim JH, Ushijima Y, Akashi A, Yamaguchi Y, et al. Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells. Nat Commun. 2022;13(1):1624.","journal-title":"Nat Commun"},{"issue":"12","key":"3673_CR7","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1182\/blood.2021011921","volume":"139","author":"T Yasuda","year":"2022","unstructured":"Yasuda T, Sanada M, Kawazu M, Kojima S, Tsuzuki S, Ueno H, et al. Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1\/2 mutations. Blood. 2022;139(12):1850\u201362.","journal-title":"Blood"},{"issue":"12","key":"3673_CR8","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.cancergen.2015.10.003","volume":"208","author":"V Aikawa","year":"2015","unstructured":"Aikawa V, Porter D, Luskin MR, Bagg A, Morrissette JJ. Transmission of an expanding donor-derived del(20q) clone through allogeneic hematopoietic stem cell transplantation without the development of a hematologic neoplasm. Cancer Genet. 2015;208(12):625\u20139.","journal-title":"Cancer Genet"},{"key":"3673_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.22951","volume":"33","author":"J Yoon","year":"2019","unstructured":"Yoon J, Yun JW, Jung CW, Kim H-J, Kim S-H. Clonal dominance of a donor-derived del(20q) clone after allogeneic hematopoietic stem cell transplantation in an acute myeloid leukemia patient with del(20q). J Clin Lab Anal. 2019;33: e22951.","journal-title":"J Clin Lab Anal"},{"issue":"18","key":"3673_CR10","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1182\/blood.2019003079","volume":"135","author":"S Boettcher","year":"2020","unstructured":"Boettcher S, Wilk CM, Singer J, Beier F, Burcklen E, Beisel C, et al. Clonal hematopoiesis in donors and long-term survivors of related allogeneic hematopoietic stem cell transplantation. Blood. 2020;135(18):1548\u201359.","journal-title":"Blood."},{"issue":"10","key":"3673_CR11","doi-asserted-by":"publisher","first-page":"3962","DOI":"10.1111\/cas.15094","volume":"112","author":"S Asada","year":"2021","unstructured":"Asada S, Kitamura T. Clonal hematopoiesis and associated diseases: a review of recent findings. Cancer Sci. 2021;112(10):3962\u201371.","journal-title":"Cancer Sci"},{"issue":"13","key":"3673_CR12","doi-asserted-by":"publisher","first-page":"3548","DOI":"10.1182\/blood-2010-04-281394","volume":"117","author":"B Grzywacz","year":"2011","unstructured":"Grzywacz B, Kataria N, Kataria N, Blazar BR, Miller JS, Verneris MR. Natural killer-cell differentiation by myeloid progenitors. Blood. 2011;117(13):3548\u201358.","journal-title":"Blood."},{"issue":"1","key":"3673_CR13","doi-asserted-by":"publisher","first-page":"22097","DOI":"10.1038\/s41598-022-25856-1","volume":"12","author":"SK Jeong","year":"2022","unstructured":"Jeong SK, Oh SJ, Kim SH, Jang S, Kang YR, Kim H, et al. Dicentric chromosome assay using a deep learning-based automated system. Sci Rep. 2022;12(1):22097.","journal-title":"Sci Rep."},{"key":"3673_CR14","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1093\/genetics\/23.4.315","volume":"23","author":"B McClintock","year":"1938","unstructured":"McClintock B. The production of homozygous deficient tissues with mutant characteristics by means of the aberrant mitotic behavior of ring-shaped chromosomes. Genetics. 1938;23:315\u201376.","journal-title":"Genetics"},{"key":"3673_CR15","doi-asserted-by":"publisher","first-page":"4340","DOI":"10.1038\/s41467-018-06545-y","volume":"9","author":"V Barra","year":"2018","unstructured":"Barra V, Fachinetti D. The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA. Nat Commun. 2018;9:4340.","journal-title":"Nat Commun"},{"key":"3673_CR16","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1002\/gcc.20806","volume":"49","author":"RN Mackinnon","year":"2010","unstructured":"Mackinnon RN, Selan C, Wall M, Baker E, Nandurkar H, Campbell LJ. The paradox of 20q11.21 amplification in a subset of cases of myeloid malignancy with chromosome 20 deletion. Genes Chromosom Cancer. 2010;49:998\u20131013.","journal-title":"Genes Chromosom Cancer"}],"container-title":["International Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-023-03673-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12185-023-03673-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-023-03673-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T12:26:26Z","timestamp":1704457586000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12185-023-03673-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,18]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["3673"],"URL":"https:\/\/doi.org\/10.1007\/s12185-023-03673-0","relation":{},"ISSN":["0925-5710","1865-3774"],"issn-type":[{"value":"0925-5710","type":"print"},{"value":"1865-3774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,18]]},"assertion":[{"value":"1 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of interest associated with this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All the patient samples were obtained with written informed consent, in compliance with the Declaration of Helsinki, and with the approval of the ethics review committee of Konan Kosei Hospital. Additionally, consent for publication in print was obtained from the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics statement"}}]}}