{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:28:47Z","timestamp":1757618927896,"version":"3.44.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Hematol"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1007\/s12185-025-04032-x","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T18:27:09Z","timestamp":1752517629000},"page":"368-371","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High-dose thiotepa may induce inappropriate secretion of antidiuretic hormone syndrome (SIADH) during conditioning treatment for allogeneic stem cell transplantation"],"prefix":"10.1007","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7802-8554","authenticated-orcid":false,"given":"Maria Assunta","family":"Limongiello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Metafuni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Giammarco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugenio","family":"Galli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Sor\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Autore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Baroni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrizia","family":"Chiusolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Sica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"4032_CR1","first-page":"911","volume":"17","author":"N Kamani","year":"1996","unstructured":"Kamani N, August CS, Bunin N, Leahey A, Bayever E, Goldwein J, et al. A study of thiotepa, etoposide and fractionated total body irradiation as a preparative regimen prior to bone marrow transplantation for poor prognosis patients with neuroblastoma. Bone Marrow Transplant. 1996;17:911\u20136.","journal-title":"Bone Marrow Transplant"},{"key":"4032_CR2","first-page":"157","volume":"17","author":"JD Bitran","year":"1996","unstructured":"Bitran JD, Samuels B, Klein L, Hanauer S, Johnson L, Martinec J, et al. Tandem high-dose chemotherapy supported by hematopoietic progenitor cells yields prolonged survival in stage IV breast cancer. Bone Marrow Transplant. 1996;17:157\u201362.","journal-title":"Bone Marrow Transplant"},{"key":"4032_CR3","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1038\/sj.bmt.1701103","volume":"21","author":"JD Down","year":"1998","unstructured":"Down JD, Westerhof GR, Boudewijn A, Setroikromo R, Ploemacher RE. Thiotepa improves allogeneic bone marrow engraftment without enhancing stem cell depletion in irradiated mice. Bone Marrow Transplant. 1998;21:327\u201330.","journal-title":"Bone Marrow Transplant"},{"key":"4032_CR4","first-page":"736","volume":"49","author":"RL Heideman","year":"1989","unstructured":"Heideman RL, Cole DE, Balis F, Sato J, Reaman GH, Packer RJ, et al. Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: evidence for dose-dependent plasma clearance of thiotepa. Cancer Res. 1989;49:736\u201341.","journal-title":"Cancer Res"},{"key":"4032_CR5","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/sj.bmt.1704353","volume":"33","author":"Y Nieto","year":"2004","unstructured":"Nieto Y, Vaughan WP. Pharmacokinetics of high-dose chemotherapy. Bone Marrow Transplant. 2004;33:259\u201369.","journal-title":"Bone Marrow Transplant"},{"key":"4032_CR6","doi-asserted-by":"publisher","first-page":"3951","DOI":"10.1182\/blood.V89.11.3951","volume":"89","author":"A Nagler","year":"1997","unstructured":"Nagler A, Ackerstein A, Or R, Naparstek E, Slavin S. Immunotherapy with recombinant human interleukin-2 and recombinant interferon-alpha in lymphoma patients postautologous marrow or stem cell transplantation. Blood. 1997;89:3951\u20139.","journal-title":"Blood"},{"key":"4032_CR7","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1182\/blood.V88.1.353.353","volume":"88","author":"A Bacigalupo","year":"1996","unstructured":"Bacigalupo A, Van Lint MT, Valbonesi M, Lercari G, Carlier P, Lamparelli T, et al. Thiotepa cyclophosphamide followed by granulocyte colony-stimulating factor mobilized allogeneic peripheral blood cells in adults with advanced leukemia. Blood. 1996;88:353\u20137.","journal-title":"Blood"},{"key":"4032_CR8","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1038\/sj.bmt.1705863","volume":"40","author":"A Bacigalupo","year":"2007","unstructured":"Bacigalupo A, Raiola AM, Lamparelli T, Gualandi F, Occhini D, Bregante S, et al. Thiotepa-based reduced intensity conditioning regimen: a 10 year follow up. Bone Marrow Transplant. 2007;40:1091\u20133.","journal-title":"Bone Marrow Transplant"},{"key":"4032_CR9","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1038\/bmt.2016.239","volume":"52","author":"S Eder","year":"2017","unstructured":"Eder S, Labopin M, Finke J, Bunjes D, Olivieri A, Santarone S, Rambaldi A, Kanz L, Messina G, Mohty M, Nagler A. Safety and efficacy of thiotepa-based conditioning for allogeneic transplantation in AML: a survey from the ALWP of the EBMT. Bone Marrow Transplant. 2017;52:238\u201344.","journal-title":"Bone Marrow Transplant"},{"key":"4032_CR10","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.bbmt.2009.09.001","volume":"16","author":"J Sanz","year":"2010","unstructured":"Sanz J, Sanz MA, Saavedra S, Lorenzo I, Montesinos P, Senent L, Planelles D, Larrea L, Mart\u00edn G, Palau J, Jarque I, Mart\u00ednez J, de la Rubia J, et al. Cord blood transplantation from unrelated donors in adults with high-risk acute myeloid leukemia. Biol Blood Marrow Transplant. 2010;16:86\u201394.","journal-title":"Biol Blood Marrow Transplant"},{"key":"4032_CR11","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1038\/bmt.2012.13","volume":"47","author":"J Sanz","year":"2012","unstructured":"Sanz J, Boluda JC, Mart\u00edn C, Gonz\u00e1lez M, Ferr\u00e1 C, Serrano D, de Heredia CD, Barrenetxea C, Martinez AM, Solano C, Sanz MA, Sanz GF. Grupo Espa\u00f1ol de Trasplante Hematopoy\u00e9tico y Terapia Celular (GETH) single-unit umbilical cord blood transplantation from unrelated donors in patients with hematological malignancy using busulfan, thiotepa, fludarabine and ATG as myeloablative conditioning regimen. Bone Marrow Transplant. 2012;47:1287\u201393.","journal-title":"Bone Marrow Transplant"},{"key":"4032_CR12","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1038\/sj.bmt.1701922","volume":"24","author":"S Sica","year":"1999","unstructured":"Sica S, Cicconi S, Sor\u00e0 F, Chiusolo P, Piccirillo N, Laurenti L, Ortu La Barbera E, Giordano G, Leone G. Inappropriate antidiuretic hormone secretion after high-dose thiotepa. Bone Marrow Transplant. 1999;24:571\u20132.","journal-title":"Bone Marrow Transplant"},{"issue":"2","key":"4032_CR13","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/j.1365-2796.1995.tb00907.x","volume":"238","author":"JB S\u00f8rensen","year":"1995","unstructured":"S\u00f8rensen JB, Andersen MK, Hansen HH. Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in malignant disease. J Intern Med. 1995;238(2):97\u2013110.","journal-title":"J Intern Med"},{"issue":"1","key":"4032_CR14","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1186\/s12882-022-02818-3","volume":"23","author":"M Wang","year":"2022","unstructured":"Wang M, Zhang L, Jia M, Wang J, Shen Z, Wang S, Zhang X, Xu J, Zheng Z, Lv X, Zong X, Li H, Zhou J, Meng T, Chen M, Zhao B, Gong J. Syndrome of inappropriate antidiuretic hormone secretion is associated with different proton pump inhibitor use: a pharmacovigilance study. BMC Nephrol. 2022;23(1):191.","journal-title":"BMC Nephrol"},{"key":"4032_CR15","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.seizure.2018.04.025","volume":"59","author":"H Falhammara","year":"2018","unstructured":"Falhammara H, Lindhc JD, Calissendorffa J, Farmandd S, Skova J, Nathansond D, Mannheimerd B. Differences in associations of antiepileptic drugs and hospitalization due to hyponatremia: a population\u2013based case\u2013control study. Seizure. 2018;59:28\u201333.","journal-title":"Seizure"},{"key":"4032_CR16","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1634\/theoncologist.2011-0400","volume":"17","author":"JJ Castillo","year":"2012","unstructured":"Castillo JJ, Vincent M, Justice E. Diagnosis and management of hyponatremia in cancer patients. Oncologist. 2012;17:756\u201365.","journal-title":"Oncologist"}],"container-title":["International Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-025-04032-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12185-025-04032-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12185-025-04032-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T09:27:18Z","timestamp":1757237238000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12185-025-04032-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,14]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["4032"],"URL":"https:\/\/doi.org\/10.1007\/s12185-025-04032-x","relation":{},"ISSN":["0925-5710","1865-3774"],"issn-type":[{"type":"print","value":"0925-5710"},{"type":"electronic","value":"1865-3774"}],"subject":[],"published":{"date-parts":[[2025,7,14]]},"assertion":[{"value":"26 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest in relation to this work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}