{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:40:54Z","timestamp":1791988854272,"version":"4.4.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":1787,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["2017\/25\/B\/NZ6\/00305"],"award-info":[{"award-number":["2017\/25\/B\/NZ6\/00305"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Stress and Chaperones"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1007\/s12192-018-0951-9","type":"journal-article","created":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T16:23:20Z","timestamp":1542817400000},"page":"283-287","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"title":["Autoantibodies to heat shock proteins 60, 70, and 90 in patients with rheumatoid arthritis"],"prefix":"10.1016","volume":"24","author":[{"given":"Jagoda","family":"Mantej","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kinga","family":"Polasik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Piotrowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1288-0511","authenticated-orcid":false,"given":"Stefan","family":"Tukaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1007\/s12192-018-0951-9_bb0010","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/intimm\/dxh063","article-title":"Immune modulation with high-dose heat-shock protein gp96: therapy of murine autoimmune diabetes and encephalomyelitis","volume":"16","author":"Chandawarkar","year":"2004","journal-title":"Int Immunol"},{"key":"10.1007\/s12192-018-0951-9_bb0015","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41413-018-0016-9","article-title":"Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies","volume":"6","author":"Guo","year":"2018","journal-title":"Bone Res"},{"key":"10.1007\/s12192-018-0951-9_bb0020","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s12192-008-0068-7","article-title":"Guidelines for the nomenclature of the human heat shock proteins","volume":"14","author":"Kampinga","year":"2009","journal-title":"Cell Stress Chaperones"},{"key":"10.1007\/s12192-018-0951-9_bb0025","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s12192-014-0507-6","article-title":"Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis","volume":"9","author":"Kasperkiewicz","year":"2014","journal-title":"Cell Stress Chaperones"},{"key":"10.1007\/s12192-018-0951-9_bb0030","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1002\/art.24916","article-title":"Epitope-specific immunotherapy of rheumatoid arthritis: clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase II trial","volume":"60","author":"Koffeman","year":"2009","journal-title":"Arthritis Rheum"},{"key":"10.1007\/s12192-018-0951-9_bb0035","doi-asserted-by":"crossref","unstructured":"Kotlarz A, Tukaj S, Krzewski K, Brycka E, Lipinska B (2013) Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis. Cell Stress Chaperones 18:653\u2013659. https:\/\/doi.org\/10.1007\/s12192-013-0407-1","DOI":"10.1007\/s12192-013-0407-1"},{"key":"10.1007\/s12192-018-0951-9_bb0040","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1002\/eji.200939593","article-title":"Treg suppress CTL responses upon immunization with HSP gp96","volume":"39","author":"Liu","year":"2009","journal-title":"Eur J Immunol"},{"key":"10.1007\/s12192-018-0951-9_bb0045","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3109\/08820139809022710","article-title":"Detection of heat shock protein 70 (Hsp70) and anti-Hsp70 antibodies in the serum of normal individuals","volume":"27","author":"Pockley","year":"1998","journal-title":"Immunol Investig"},{"key":"10.1007\/s12192-018-0951-9_bb0050","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1054\/csac.1998.0121","article-title":"Identification of human heat shock protein 60 (Hsp60) and anti-Hsp60 antibodies in the peripheral circulation of normal individuals","volume":"4","author":"Pockley","year":"1999","journal-title":"Cell Stress Chaperones"},{"key":"10.1007\/s12192-018-0951-9_bb0055","doi-asserted-by":"crossref","first-page":"3712","DOI":"10.1002\/art.20635","article-title":"Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein","volume":"50","author":"Quintana","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1007\/s12192-018-0951-9_bb0060","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/rheumatology\/kew266","article-title":"Heat shock proteins and their immunomodulatory role in inflammatory arthritis","volume":"56","author":"Spierings","year":"2017","journal-title":"Rheumatology (Oxford)"},{"key":"10.1007\/s12192-018-0951-9_bb0065","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nri749","article-title":"Roles of heat-shock proteins in innate and adaptive immunity","volume":"2","author":"Srivastava","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"10.1007\/s12192-018-0951-9_bb0070","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/nrc2887","article-title":"Targeting the dynamic HSP90 complex in cancer","volume":"10","author":"Trepel","year":"2010","journal-title":"Nat Rev Cancer"},{"key":"10.1007\/s12192-018-0951-9_bb0075","doi-asserted-by":"crossref","first-page":"722","DOI":"10.5604\/17322693.1107329","article-title":"Immunoregulatory properties of Hsp70","volume":"68","author":"Tukaj","year":"2014","journal-title":"Postepy Hig Med Dosw"},{"key":"10.1007\/s12192-018-0951-9_bb0080","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s12192-016-0670-z","article-title":"Anti-Hsp90 therapy in autoimmune and inflammatory diseases: a review of preclinical studies","volume":"21","author":"Tukaj","year":"2016","journal-title":"Cell Stress Chaperones"},{"key":"10.1007\/s12192-018-0951-9_bb0085","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s12192-010-0168-z","article-title":"Hsp40 proteins modulate humoral and cellular immune response in rheumatoid arthritis patients","volume":"15","author":"Tukaj","year":"2010","journal-title":"Cell Stress Chaperones"},{"key":"10.1007\/s12192-018-0951-9_bb0090","doi-asserted-by":"crossref","first-page":"327","DOI":"10.18388\/abp.2010_2412","article-title":"Cytokines of the Th1 and Th2 type in sera of rheumatoid arthritis patients; correlations with anti-Hsp40 immune response and diagnostic markers","volume":"57","author":"Tukaj","year":"2010","journal-title":"Acta Biochim Pol"},{"key":"10.1007\/s12192-018-0951-9_bb0095","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jsbmb.2016.10.002","article-title":"Autoimmunity to heat shock proteins and vitamin D status in patients with celiac disease without associated dermatitis herpetiformis","volume":"173","author":"Tukaj","year":"2017","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1007\/s12192-018-0951-9_bb0100","doi-asserted-by":"crossref","first-page":"6463","DOI":"10.4049\/jimmunol.168.12.6463","article-title":"Resistance to adjuvant arthritis is due to protective antibodies against heat shock protein surface epitopes and the induction of IL-10 secretion","volume":"168","author":"Ulmansky","year":"2002","journal-title":"J Immunol"},{"key":"10.1007\/s12192-018-0951-9_bb0105","doi-asserted-by":"crossref","first-page":"5103","DOI":"10.4049\/jimmunol.1500023","article-title":"A humanized monoclonal antibody against heat shock protein 60 suppresses murine arthritis and colitis and skews the cytokine balance toward an anti-inflammatory response","volume":"194","author":"Ulmansky","year":"2015","journal-title":"J Immunol"},{"key":"10.1007\/s12192-018-0951-9_bb0110","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/nri1593","article-title":"Heat-shock proteins induce T-cell regulation of chronic inflammation","volume":"5","author":"van Eden","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1007\/s12192-018-0951-9_bb0115","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.3389\/fimmu.2017.01599","article-title":"The enigma of heat shock proteins in immune tolerance","volume":"8","author":"van Eden","year":"2017","journal-title":"Front Immunol"},{"key":"10.1007\/s12192-018-0951-9_bb0120","doi-asserted-by":"crossref","first-page":"14134","DOI":"10.1073\/pnas.1206803109","article-title":"Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis","volume":"109","author":"van Herwijnen","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1007\/s12192-018-0951-9_bb0125","doi-asserted-by":"crossref","first-page":"e4186","DOI":"10.1371\/journal.pone.0004186","article-title":"IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis","volume":"4","author":"Wieten","year":"2009","journal-title":"PLoS One"}],"container-title":["Cell Stress and Chaperones"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12192-018-0951-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12192-018-0951-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355814523017510?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355814523017510?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12192-018-0951-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T01:14:12Z","timestamp":1761182052000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1355814523017510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S1355814523017510"],"URL":"https:\/\/doi.org\/10.1007\/s12192-018-0951-9","relation":{},"ISSN":["1355-8145"],"issn-type":[{"value":"1355-8145","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autoantibodies to heat shock proteins 60, 70, and 90 in patients with rheumatoid arthritis","name":"articletitle","label":"Article Title"},{"value":"Cell Stress and Chaperones","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s12192-018-0951-9","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2018 THE AUTHOR(S). Published by Elsevier Inc on behalf of Cell Stress Society International","name":"copyright","label":"Copyright"}]}}