{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T12:11:46Z","timestamp":1785845506420,"version":"3.56.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":1178,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"the Special Fund of the Fourth Affiliated Hospital of Harbin Medical University","award":["HYDSYTB201913"],"award-info":[{"award-number":["HYDSYTB201913"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Stress and Chaperones"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s12192-020-01111-2","type":"journal-article","created":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T18:05:31Z","timestamp":1587492331000},"page":"767-777","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Inhibition of hsa_circ_0002570 suppresses high-glucose\u2013induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-1243\/angiomotin axis"],"prefix":"10.1016","volume":"25","author":[{"given":"Guodan","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shifeng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinge","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuchen","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1007\/s12192-020-01111-2_bb0010","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1167\/iovs.17-23193","article-title":"Characteristics of retinal structural and microvascular alterations in early type 2 diabetic patients","volume":"59","author":"Chen","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1007\/s12192-020-01111-2_bb0015","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.1038\/s41467-019-11162-4","article-title":"circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1","volume":"10","author":"Cheng","year":"2019","journal-title":"Nat Commun"},{"key":"10.1007\/s12192-020-01111-2_bb0020","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/s13577-019-00240-w","article-title":"Down-regulation of miR-377 suppresses high glucose and hypoxia-induced angiogenesis and inflammation in human retinal endothelial cells by direct up-regulation of target gene SIRT1","volume":"32","author":"Cui","year":"2019","journal-title":"Hum Cell"},{"key":"10.1007\/s12192-020-01111-2_bb0025","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s10456-007-9067-z","article-title":"Vascular permeability in ocular disease and the role of tight junctions","volume":"10","author":"Erickson","year":"2007","journal-title":"Angiogenesis"},{"key":"10.1007\/s12192-020-01111-2_bb0030","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1002\/jcb.28978","article-title":"miR-152\/LIN28B axis modulates high-glucose-induced angiogenesis in human retinal endothelial cells via VEGF signaling","volume":"121","author":"Fu","year":"2020","journal-title":"J Cell Biochem"},{"key":"10.1007\/s12192-020-01111-2_bb0035","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/j.1745-7254.2008.00797.x","article-title":"Scutellarein inhibits hypoxia- and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells","volume":"29","author":"Gao","year":"2008","journal-title":"Acta Pharmacol Sin"},{"key":"10.1007\/s12192-020-01111-2_bb0040","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1159\/000479156","article-title":"Altered Expression Profile of Circular RNAs in the Serum of Patients with Diabetic Retinopathy Revealed by Microarray","volume":"58","author":"Gu","year":"2017","journal-title":"Ophthalmic Res"},{"key":"10.1007\/s12192-020-01111-2_bb0045","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.pharmthera.2018.01.010","article-title":"Circular RNA and its mechanisms in disease: From the bench to the clinic","volume":"187","author":"Han","year":"2018","journal-title":"Pharmacol Ther"},{"key":"10.1007\/s12192-020-01111-2_bb0050","doi-asserted-by":"crossref","unstructured":"He M et al (2019) Comparison of expression profiling of circular RNAs in vitreous humour between diabetic retinopathy and non-diabetes mellitus patients. Acta Diabetol. https:\/\/doi.org\/10.1007\/s00592-019-01448-w","DOI":"10.1007\/s00592-019-01448-w"},{"key":"10.1007\/s12192-020-01111-2_bb0055","first-page":"C1647","article-title":"High glucose promotes retinal endothelial cell migration through activation of Src, PI3K\/Akt1\/eNOS, and ERKs","volume":"295","author":"Huang","year":"2008","journal-title":"Am J Phys Cell Phys"},{"key":"10.1007\/s12192-020-01111-2_bb0060","doi-asserted-by":"crossref","first-page":"4821","DOI":"10.1002\/jcb.26153","article-title":"LncRNA-MALAT1 promotes angiogenesis of thyroid cancer by modulating tumor-associated macrophage FGF2 protein secretion","volume":"118","author":"Huang","year":"2017","journal-title":"J Cell Biochem"},{"key":"10.1007\/s12192-020-01111-2_bb0065","doi-asserted-by":"crossref","first-page":"994","DOI":"10.2337\/db16-1199","article-title":"Developmental role of macrophage Cannabinoid-1 receptor signaling in type 2 diabetes","volume":"66","author":"Jourdan","year":"2017","journal-title":"Diabetes"},{"key":"10.1007\/s12192-020-01111-2_bb0070","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.preteyeres.2013.02.001","article-title":"Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions","volume":"34","author":"Klaassen","year":"2013","journal-title":"Prog Retin Eye Res"},{"key":"10.1007\/s12192-020-01111-2_bb0075","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1161\/CIRCRESAHA.112.270520","article-title":"Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice","volume":"111","author":"Liu","year":"2012","journal-title":"Circ Res"},{"key":"10.1007\/s12192-020-01111-2_bb0080","doi-asserted-by":"crossref","unstructured":"Liu P, Jia SB, Shi JM, Li WJ, Tang LS, Zhu XH, Tong P (2019) LncRNA-MALAT1 promotes neovascularization in diabetic retinopathy through regulating miR-125b\/VE-cadherin axis. Biosci Rep 39. https:\/\/doi.org\/10.1042\/bsr20181469","DOI":"10.1042\/BSR20181469"},{"key":"10.1007\/s12192-020-01111-2_bb0085","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.vph.2017.11.002","article-title":"Chlorogenic acid attenuates diabetic retinopathy by reducing VEGF expression and inhibiting VEGF-mediated retinal neoangiogenesis","volume":"101","author":"Mei","year":"2018","journal-title":"Vasc Pharmacol"},{"key":"10.1007\/s12192-020-01111-2_bb0090","doi-asserted-by":"crossref","first-page":"8168","DOI":"10.1093\/nar\/gky721","article-title":"Circular RNA expression in human hematopoietic cells is widespread and cell-type specific","volume":"46","author":"Nicolet","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"10.1007\/s12192-020-01111-2_bb0095","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1136\/bjophthalmol-2011-300539","article-title":"Global estimates of visual impairment: 2010","volume":"96","author":"Pascolini","year":"2012","journal-title":"Br J Ophthalmol"},{"key":"10.1007\/s12192-020-01111-2_bb0100","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.tig.2016.03.002","article-title":"Circular RNA Expression: Its Potential Regulation and Function","volume":"32","author":"Salzman","year":"2016","journal-title":"Trends Genet"},{"key":"10.1007\/s12192-020-01111-2_bb0105","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.preteyeres.2015.08.001","article-title":"The progress in understanding and treatment of diabetic retinopathy","volume":"51","author":"Stitt","year":"2016","journal-title":"Prog Retin Eye Res"},{"key":"10.1007\/s12192-020-01111-2_bb0110","doi-asserted-by":"crossref","first-page":"e0137887","DOI":"10.1371\/journal.pone.0137887","article-title":"Uncovering direct targets of MiR-19a involved in lung cancer progression","volume":"10","author":"Yamamoto","year":"2015","journal-title":"PLoS One"},{"key":"10.1007\/s12192-020-01111-2_bb0115","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.jdiacomp.2016.12.004","article-title":"MiR-126 overexpression inhibits high glucose-induced migration and tube formation of rhesus macaque choroid-retinal endothelial cells by obstructing VEGFA and PIK3R2","volume":"31","author":"Yang","year":"2017","journal-title":"J Diabetes Complicat"},{"key":"10.1007\/s12192-020-01111-2_bb0120","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1161\/ATVBAHA.117.309859","article-title":"CYLD deubiquitinates nicotinamide adenine dinucleotide phosphate oxidase 4 contributing to adventitial remodeling","volume":"37","author":"Yu","year":"2017","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1007\/s12192-020-01111-2_bb0125","doi-asserted-by":"crossref","first-page":"6500","DOI":"10.1167\/iovs.17-22698","article-title":"Identification and characterization of circular RNAs as a new class of putative biomarkers in diabetes retinopathy","volume":"58","author":"Zhang","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1007\/s12192-020-01111-2_bb0130","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1159\/000484061","article-title":"Nogo-B promotes angiogenesis in proliferative diabetic retinopathy via VEGF\/PI3K\/Akt pathway in an autocrine manner","volume":"43","author":"Zhang","year":"2017","journal-title":"Cell Physiol Biochem"},{"key":"10.1007\/s12192-020-01111-2_bb0135","first-page":"4460","article-title":"Apatinib suppresses breast cancer cells proliferation and invasion via angiomotin inhibition","volume":"11","author":"Zhang","year":"2019","journal-title":"Am J Transl Res"},{"key":"10.1007\/s12192-020-01111-2_bb0140","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.ebiom.2019.10.004","article-title":"Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI","volume":"49","author":"Zhu","year":"2019","journal-title":"EBioMedicine"}],"container-title":["Cell Stress and Chaperones"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12192-020-01111-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12192-020-01111-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355814523012397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355814523012397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12192-020-01111-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T01:15:39Z","timestamp":1761182139000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1355814523012397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S1355814523012397"],"URL":"https:\/\/doi.org\/10.1007\/s12192-020-01111-2","relation":{},"ISSN":["1355-8145"],"issn-type":[{"value":"1355-8145","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of hsa_circ_0002570 suppresses high-glucose\u2013induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-1243\/angiomotin axis","name":"articletitle","label":"Article Title"},{"value":"Cell Stress and Chaperones","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s12192-020-01111-2","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2020 THE AUTHOR(S). Published by Elsevier Inc on behalf of Cell Stress Society International","name":"copyright","label":"Copyright"}]}}