{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T04:30:22Z","timestamp":1781929822690,"version":"3.54.5"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T00:00:00Z","timestamp":1520208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100009553","name":"Agentura pro zdravotnick\u00fd v\u00fdzkum \u010cesk\u00e9 republiky","doi-asserted-by":"crossref","award":["15-31269A"],"award-info":[{"award-number":["15-31269A"]}],"id":[{"id":"10.13039\/501100009553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["00064203"],"award-info":[{"award-number":["00064203"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Folia Microbiol"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1007\/s12223-018-0589-0","type":"journal-article","created":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T11:36:15Z","timestamp":1520249775000},"page":"525-532","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Rare case of osteomyelitis of tibial shaft caused by Nocardia cyriacigeorgica"],"prefix":"10.1007","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0569-7260","authenticated-orcid":false,"given":"D.","family":"Raszka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"S.","family":"Popelka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"He\u0159t","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Jahoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Landor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Vav\u0159\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,3,5]]},"reference":[{"issue":"12","key":"589_CR1","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.3928\/0147-7447-19891201-12","volume":"12","author":"LC Almekinders","year":"1989","unstructured":"Almekinders LC, Lachiewicz PF (1989) Nocardia osteomyelitis: case report and review of the literature. Orthopedics 12(12):1583\u20131585. \n                    https:\/\/doi.org\/10.3928\/0147-7447-19891201-12","journal-title":"Orthopedics"},{"issue":"4","key":"589_CR2","doi-asserted-by":"publisher","first-page":"434","DOI":"10.4103\/0970-2113.184920","volume":"33","author":"R Arjun","year":"2016","unstructured":"Arjun R, Padmanabhan A, Attunuru BPR, Gupta P (2016) Disseminated nocardiosis masqueradin as metastatic malignancy. Lung India 33(4):434\u2013438. \n                    https:\/\/doi.org\/10.4103\/0970-2113.184920","journal-title":"Lung India"},{"issue":"3","key":"589_CR3","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1590\/S1413-86702008000300018","volume":"12","author":"IG Baraboutis","year":"2008","unstructured":"Baraboutis IG, Argyropoulou A, Papastamopoulos V, Psaroudaki Z, Paniara O, Skoutelis AT (2008) Primary sternal osteomyelitis caused by Nocardia nova: case report and literature review. Braz J Infect Dis 12(3):257\u2013259. \n                    https:\/\/doi.org\/10.1590\/S1413-86702008000300018","journal-title":"Braz J Infect Dis"},{"issue":"3","key":"589_CR4","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1128\/JCM.06243-11","volume":"50","author":"BA Brown-Elliott","year":"2012","unstructured":"Brown-Elliott BA, Biehle J, Conville SP et al (2012) Sulfonamide resistance in isolates of Nocardia spp. from a U.S. multicenter survey. J Clin Microbiol 50(3):670\u2013672. \n                    https:\/\/doi.org\/10.1128\/JCM.06243-11","journal-title":"J Clin Microbiol"},{"issue":"2","key":"589_CR5","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1128\/JCM.02128-15","volume":"54","author":"SP Buckwalter","year":"2016","unstructured":"Buckwalter SP, Olson SL, Connelly BJ, Lucas BC, Rodning AA, Walchak RC, Deml SM, Wohlfiel SL, Wengenack NL (2016) Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Mycobacterium species, Nocardia species, and other aerobic actinomycetes. J Clin Microbiol 54(2):376\u2013384. \n                    https:\/\/doi.org\/10.1128\/JCM.02128-15","journal-title":"J Clin Microbiol"},{"issue":"11","key":"589_CR6","doi-asserted-by":"publisher","first-page":"3602","DOI":"10.1128\/JCM.00515-13","volume":"51","author":"G Carrasco","year":"2013","unstructured":"Carrasco G, Valdezate S, Garrido N, Villal\u00f3n P, Medina-Pascual MJ, S\u00e1ez-Nieto JA (2013) Identification, typing, and phylogenetic relationships of the main clinical Nocardia species in Spain according to their gyrB and rpoB genes. J Clin Microbiol 51(11):3602\u20133608. \n                    https:\/\/doi.org\/10.1128\/JCM.00515-13","journal-title":"J Clin Microbiol"},{"key":"589_CR7","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00542","volume":"7","author":"G Carrasco","year":"2016","unstructured":"Carrasco G, De Dios Caballero J, Garrido N, Valdezate S, Cant\u00f3n R, S\u00e1ez-Nieto JA (2016) Shortcomings of the commercial MALDI-TOF MS database and use of MLSA as an arbiter in the identification of Nocardia species. Front Microbiol 7:542. \n                    https:\/\/doi.org\/10.3389\/fmicb.2016.00542","journal-title":"Front Microbiol"},{"key":"589_CR8","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.rmcr.2016.03.004","volume":"18","author":"G Castellana","year":"2016","unstructured":"Castellana G, Grimaldi A, Castellana M, Farina C, Castellana G (2016) Pulmonary nocardiosis in chronic obstructive pulmonary disease: a new clinical challenge. Respir Med Case Rep 18:14\u201321. \n                    https:\/\/doi.org\/10.1016\/j.rmcr.2016.03.004","journal-title":"Respir Med Case Rep"},{"key":"589_CR9","unstructured":"Clinical Laboratory Standards Institute [CLSI] (2011) Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes. Approved Standard- M24-A2, 2nd Edn, Vol. 31 Wayne, PA: Clinical and Laboratory Standards Institute"},{"issue":"4","key":"589_CR10","first-page":"607","volume":"28","author":"PT Cruz","year":"1952","unstructured":"Cruz PT, Clancy CF (1952) Nocardial osteomyelitis and septicemia. Am J Pathol 28(4):607\u2013627","journal-title":"Am J Pathol"},{"issue":"729","key":"589_CR11","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1136\/pgmj.62.729.673","volume":"62","author":"J Luca De","year":"1986","unstructured":"De Luca J, Walsh B, Robbins W, Visconti EB (1986) Nocardia asteroides osteomyelitis. Postgrad Med J 62(729):673\u2013674. \n                    https:\/\/doi.org\/10.1136\/pgmj.62.729.673","journal-title":"Postgrad Med J"},{"issue":"1","key":"589_CR12","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1128\/JCM.44.1.280-282.2006","volume":"44","author":"S Elsayed","year":"2006","unstructured":"Elsayed S, Kealey A, Coffin CS, Read R, Megran D, Zhang K (2006) Nocardia cyriacigeorgica septicemia. J Clin Microbiol 44(1):280\u2013282. \n                    https:\/\/doi.org\/10.1128\/JCM.44.1.280-282.2006","journal-title":"J Clin Microbiol"},{"issue":"4","key":"589_CR13","doi-asserted-by":"publisher","first-page":"389","DOI":"10.3109\/17453679108994479","volume":"62","author":"J Guiral","year":"1991","unstructured":"Guiral J, Refolio C, Carrero P, Carbajosa S (1991) Sacral osteomyelitis due to Nocardia asteroides. Acta Orthop Scand 62(4):389\u2013390. \n                    https:\/\/doi.org\/10.3109\/17453679108994479","journal-title":"Acta Orthop Scand"},{"issue":"1","key":"589_CR14","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1128\/JCM.0669-06","volume":"45","author":"F Hamdad","year":"2007","unstructured":"Hamdad F, Vidal B, Douadi Y, Laurans G, Canarelli B, Choukroun G, Rodriguez-Nava V, Boiron P, Beaman B, Eb F (2007) Nocardia nova as the causative agent in spondylodiscitis and psoas abscess. J Clin Microbiol 45(1):262\u2013265. \n                    https:\/\/doi.org\/10.1128\/JCM.0669-06","journal-title":"J Clin Microbiol"},{"key":"589_CR15","doi-asserted-by":"publisher","unstructured":"Hashemi-Shahraki A, Heidarieh P, Bostanabad SZ, Hashemzadeh M, Feizabadi MM, Schraufnagel D, Mirsaeidi M (2015) Genetic diversity and antimicrobial susceptibility of Nocardia species among patients with nocardiosis. Sci Rep 5(1). \n                    https:\/\/doi.org\/10.1038\/srep17862","DOI":"10.1038\/srep17862"},{"issue":"3","key":"589_CR16","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1097\/BOT.0b013e318199e8d9","volume":"23","author":"TV Heiden","year":"2009","unstructured":"Heiden TV, Stahel PF, Clutter S, Price C, Peterson SL, Morgan SJ (2009) Nocardia osteomyelitis: a rare complication after intramedullary nailing of a closed tibial shaft fracture. J Orthop Trauma 23(3):232\u2013236. \n                    https:\/\/doi.org\/10.1097\/BOT.0b013e318199e8d9","journal-title":"J Orthop Trauma"},{"key":"589_CR17","doi-asserted-by":"publisher","unstructured":"Johnson P, Ammar H (2013) Nocardia brasiliensis vertebral osteomyelitis and epidural abscess. BMJ Case Rep 2013:bcr2012008400. \n                    https:\/\/doi.org\/10.1136\/bcr-2012-008400","DOI":"10.1136\/bcr-2012-008400"},{"issue":"1","key":"589_CR18","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s11046-005-3050-2","volume":"160","author":"A Kageyama","year":"2005","unstructured":"Kageyama A, Hoshino Y, Yazawa K, Poonwan N, Takeshita N, Maki S, Mikami Y (2005) Nocardia cyriacigeorgica is a significant pathogen responsible for nocardiosis in Japan and Thailand. Mycopathologia 160(1):15\u201319. \n                    https:\/\/doi.org\/10.1007\/s11046-005-3050-2","journal-title":"Mycopathologia"},{"issue":"10","key":"589_CR19","doi-asserted-by":"publisher","first-page":"3366","DOI":"10.1128\/JCM.00780-15","volume":"53","author":"PD Khot","year":"2015","unstructured":"Khot PD, Bird BA, Durrant RJ, Fisher MA (2015) Identification of Nocardia species by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol 53(10):3366\u20133369. \n                    https:\/\/doi.org\/10.1128\/JCM.00780-15","journal-title":"J Clin Microbiol"},{"key":"589_CR20","first-page":"111","volume":"43","author":"M Kostur","year":"2002","unstructured":"Kostur M, Storey D (2002) Nocardia farcinica osteomyelitis of the frontal bone five years after Nocardia brain abscess in an immunocompetent patient. J Miss State Med Assoc 43:111","journal-title":"J Miss State Med Assoc"},{"issue":"10","key":"589_CR21","doi-asserted-by":"publisher","first-page":"837","DOI":"10.2106\/JBJS.N.01350","volume":"97","author":"HM Kremers","year":"2015","unstructured":"Kremers HM, Nwojo ME, Ransom JE, Wood-Wentz CM, Melton LJ III, Huddleston PM III (2015) Trends in the epidemiology of osteomyelitis: a population-based study, 1969 to 2009. J Bone Joint Surg Am 97(10):837\u2013845. \n                    https:\/\/doi.org\/10.2106\/JBJS.N.01350","journal-title":"J Bone Joint Surg Am"},{"issue":"6","key":"589_CR22","doi-asserted-by":"publisher","first-page":"2995","DOI":"10.1128\/AAC.01279-10","volume":"55","author":"J Larruskain","year":"2011","unstructured":"Larruskain J, Idigoras P, Marim\u00f3n JM, Per\u00e9z-Trallero E (2011) Susceptibility of 186 Nocardia sp. isolates to 20 antimicrobial agents. Antimicrob Agents Chemother 55(6):2995\u20132998. \n                    https:\/\/doi.org\/10.1128\/AAC.01279-10","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"589_CR23","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1016\/j.jocn.2009.12.022","volume":"17","author":"J Lee","year":"2010","unstructured":"Lee J, Whitby M, Hall BI (2010) Nocardia cyriacigeorgica abscess of the conus medullaris in an immunocompetent host. J Clin Neurosci 17(9):1194\u20131195. \n                    https:\/\/doi.org\/10.1016\/j.jocn.2009.12.022","journal-title":"J Clin Neurosci"},{"issue":"12","key":"589_CR24","doi-asserted-by":"publisher","first-page":"4534","DOI":"10.1128\/JCM.01073-10","volume":"48","author":"W Lowman","year":"2010","unstructured":"Lowman W, Aithma N (2010) Antimicrobial susceptibility testing and profiling of Nocardia species and other aerobic actinomycetes from South Africa: comparative evaluation of broth microdilution versus the E-test. J Clin Microbiol 48(12):4534\u20134540. \n                    https:\/\/doi.org\/10.1128\/JCM.01073-10","journal-title":"J Clin Microbiol"},{"issue":"8","key":"589_CR25","first-page":"813","volume":"58","author":"M Martini","year":"1972","unstructured":"Martini M, Martini-Benkeddache Y, Bekada H, Boulahbal F (1972) Primary mycoses of tibia due to Nocardia asteroides. Rev Chir Orthop Reparatrice Appar Mot 58(8):813\u2013816","journal-title":"Rev Chir Orthop Reparatrice Appar Mot"},{"issue":"3","key":"589_CR26","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1080\/0036554021000026959","volume":"35","author":"JP Montoya","year":"2003","unstructured":"Montoya JP, Carpenter JL, Holmes GP, Hurley DL, Winn R (2003) Disseminated Nocardia transvalensis infection with osteomyelitis and multiple brain abscesses. Scand J Infect Dis 35(3):189\u2013196. \n                    https:\/\/doi.org\/10.1080\/0036554021000026959","journal-title":"Scand J Infect Dis"},{"issue":"1","key":"589_CR27","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1007\/s00256-004-0784-8","volume":"34","author":"SL Moore","year":"2005","unstructured":"Moore SL, Jones S, Lee JL (2005) Nocardia osteomyelitis in the setting of previously unknown HIV infection. Skelet Radiol 34(1):58\u201360. \n                    https:\/\/doi.org\/10.1007\/s00256-004-0784-8","journal-title":"Skelet Radiol"},{"issue":"4","key":"589_CR28","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1099\/jmm.0.46774-0","volume":"56","author":"J Mu\u00f1oz","year":"2007","unstructured":"Mu\u00f1oz J, Mirelis B, Arag\u00f3n LM et al (2007) Clinical and microbiological features of nocardiosis 1997\u20132003. J Med Microbiol 56(4):545\u2013550. \n                    https:\/\/doi.org\/10.1099\/jmm.0.46774-0","journal-title":"J Med Microbiol"},{"key":"589_CR29","first-page":"109","volume":"13","author":"MB Nagmoti","year":"2008","unstructured":"Nagmoti MB, Raviraj G, Sonali B, Nagmoti JM (2008) Nocardia asteriodes spinal osteomyelitis in an immunocompromised host from South India. Neurology Asia 13:109\u2013112","journal-title":"Neurology Asia"},{"issue":"1","key":"589_CR30","doi-asserted-by":"publisher","first-page":"189","DOI":"10.14219\/jada.archive.1973.0337","volume":"87","author":"CW Newman","year":"1973","unstructured":"Newman CW, Burdick FA (1973) Rare cause of osteomyelitis of the mandible: report of case. J Am Dent Assoc 87(1):189\u2013191. \n                    https:\/\/doi.org\/10.14219\/jada.archive.1973.0337","journal-title":"J Am Dent Assoc"},{"issue":"3","key":"589_CR31","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.antib.2008.06.002","volume":"10","author":"V Rodriguez-Nava","year":"2008","unstructured":"Rodriguez-Nava V, Zoropoguy A, Laurent F, Blaha D, Couble A, Mouni\u00e9e D, Boiron P (2008) La nocardiose, une maladie en expansion (Nocardiosis, an expanding disease). Antibiotiques 10(3):115\u2013127. \n                    https:\/\/doi.org\/10.1016\/j.antib.2008.06.002","journal-title":"Antibiotiques"},{"issue":"1","key":"589_CR32","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0732-8893(87)90045-9","volume":"8","author":"JG Schwartz","year":"1987","unstructured":"Schwartz JG, Tio FO (1987) Nocardial osteomyelitis: a case report and review of the literature. Diagn Microbiol Infect Dis 8(1):37\u201346. \n                    https:\/\/doi.org\/10.1016\/0732-8893(87)90045-9","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"8","key":"589_CR33","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1016\/j.clineuro.2010.05.009","volume":"112","author":"MB Stokes","year":"2010","unstructured":"Stokes MB, Reardon KA, O\u2019Day J (2010) Acute spinal cord compression caused by disseminated Nocardia infection involving the conus medullaris. Clin Neurol Neurosurg 112(8):726\u2013728. \n                    https:\/\/doi.org\/10.1016\/j.clineuro.2010.05.009","journal-title":"Clin Neurol Neurosurg"},{"key":"589_CR34","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.ijid.2013.11.002","volume":"20","author":"S Vanegas","year":"2014","unstructured":"Vanegas S, Franco-Cendejas R, Cicero A, L\u00f3pez-J\u00e1come E, Colin C, Hern\u00e1ndez M (2014) Nocardia brasiliensis-associated femorotibial osteomyelitis. Int J Infect Dis 20:63\u201365. \n                    https:\/\/doi.org\/10.1016\/j.ijid.2013.11.002","journal-title":"Int J Infect Dis"},{"issue":"11","key":"589_CR35","doi-asserted-by":"publisher","first-page":"4015","DOI":"10.1128\/JCM.01234-10","volume":"48","author":"A Verroken","year":"2010","unstructured":"Verroken A, Janssens M, Berhin C, Bogaerts P, Huang TD, Wauters G, Glupczynski Y (2010) Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Nocardia species. J Clin Microbiol 48(11):4015\u20134021. \n                    https:\/\/doi.org\/10.1128\/JCM.01234-10","journal-title":"J Clin Microbiol"},{"issue":"14","key":"589_CR36","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3238\/arztebl.2012.0257","volume":"109","author":"G Walter","year":"2012","unstructured":"Walter G, Kemmerer M, Kappler C, Hoffmann R (2012) Treatment algorithms for chronic osteomyelitis. Dtsch Arztebl Int 109(14):257\u2013264. \n                    https:\/\/doi.org\/10.3238\/arztebl.2012.0257","journal-title":"Dtsch Arztebl Int"},{"issue":"4","key":"589_CR37","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1309\/AJCPW84AFTUWMHYU","volume":"142","author":"HL Wang","year":"2014","unstructured":"Wang HL, Seo YH, LaSala PR, Tarrand JJ, Han XY (2014) Nocardiosis in 132 patients with cancer: microbiological and clinical analyses. Am J Clin Pathol 142(4):513\u2013523. \n                    https:\/\/doi.org\/10.1309\/AJCPW84AFTUWMHYU","journal-title":"Am J Clin Pathol"},{"issue":"4","key":"589_CR38","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.mayocp.2011.11.016","volume":"87","author":"JW Wilson","year":"2012","unstructured":"Wilson JW (2012) Nocardiosis: updates and clinical overview. Mayo Clin Proc 87(4):403\u2013407. \n                    https:\/\/doi.org\/10.1016\/j.mayocp.2011.11.016","journal-title":"Mayo Clin Proc"}],"container-title":["Folia Microbiologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12223-018-0589-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12223-018-0589-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12223-018-0589-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T12:44:53Z","timestamp":1581943493000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12223-018-0589-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,5]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["589"],"URL":"https:\/\/doi.org\/10.1007\/s12223-018-0589-0","relation":{},"ISSN":["0015-5632","1874-9356"],"issn-type":[{"value":"0015-5632","type":"print"},{"value":"1874-9356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,5]]},"assertion":[{"value":"17 August 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}