{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T10:37:52Z","timestamp":1755599872023,"version":"3.37.3"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T00:00:00Z","timestamp":1597968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T00:00:00Z","timestamp":1597968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["306355\/2018-3"],"award-info":[{"award-number":["306355\/2018-3"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["Financial Code 001"],"award-info":[{"award-number":["Financial Code 001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["2016\/25028-3"],"award-info":[{"award-number":["2016\/25028-3"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/03918-2"],"award-info":[{"award-number":["2018\/03918-2"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Folia Microbiol"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s12223-020-00814-4","type":"journal-article","created":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T15:03:21Z","timestamp":1598022201000},"page":"1033-1038","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Benzylidene-carbonyl compounds are active against itraconazole-susceptible and itraconazole-resistant Sporothrix brasiliensis"],"prefix":"10.1007","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6719-1794","authenticated-orcid":false,"given":"Stefanie Bressan","family":"Waller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlete Brum","family":"Cleff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcia Kutscher","family":"Ripoll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rio Carlos Ara\u00fajo","family":"Meireles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina Themoteo","family":"Varela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Paulo dos S.","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,21]]},"reference":[{"key":"814_CR1","unstructured":"CLSI \u2013 Clinical and Laboratory Standard Institute (2008) Reference method for broth dilution antifungal susceptibility testing of filamentous fungi: approved standard M38-A. 2008. 2nd ed. Wayne, PA, USA"},{"key":"814_CR2","doi-asserted-by":"publisher","first-page":"e01057","DOI":"10.1128\/AAC.01057-17","volume":"61","author":"A Espinel-Ingroff","year":"2017","unstructured":"Espinel-Ingroff A, Abreu DPB, Almeida-Paes R, Brilhante RSN, Chakrabarti A, Chowdhary A, Hagen F, C\u00f3rdoba S, Gonzalez GM, Govender NP, Guarro J, Johnson EM, Kidd SE, Pereira SA, Rodrigues AM, Rozental S, Szeszs MW, Ballest\u00e9 Alaniz R, Bonifaz A, Bonfietti LX, Borba-Santos LP, Capilla J, Colombo AL, Dolande M, Isla MG, Melhem MSC, Mesa-Arango AC, Oliveira MME, Panizo MM, Pires de Camargo Z, Zancope-Oliveira RM, Meis JF, Turnidge J (2017) International study of MIC\/MEC distributions for definition of epidemiological cutoff values for Sporothrix species identified by molecular methods. Antimicrob Agents Chemother 61:e01057\u2013e01017. https:\/\/doi.org\/10.1128\/AAC.01057-17","journal-title":"Antimicrob Agents Chemother"},{"key":"814_CR3","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/j.1439-0507.2009.01701.x","volume":"53","author":"MC Gutierrez-Galhardo","year":"2010","unstructured":"Gutierrez-Galhardo MC, Zancop\u00e9-Oliveira RM, Monz\u00f3n A, Rodriguez-Tudela JL, Cuenca-Estrella M (2010) Antifungal susceptibility profile in vitro of Sporothrix schenckii in two growth phases and by two methods: microdilution and E-test. Mycoses 53:227\u2013231. https:\/\/doi.org\/10.1111\/j.1439-0507.2009.01701.x","journal-title":"Mycoses"},{"key":"814_CR4","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.intimp.2016.03.010","volume":"34","author":"L Huang","year":"2016","unstructured":"Huang L, Zhang J, Song T, Yuan L, Zhou J, Yin H, He T, Gao W, Sun Y, Hu X, Huang H (2016) Antifungal curcumin promotes chitin accumulation associated with decreased virulence of Sporothrix schenckii. Int Immunopharmacol 34:263\u2013270. https:\/\/doi.org\/10.1016\/j.intimp.2016.03.010","journal-title":"Int Immunopharmacol"},{"key":"814_CR5","doi-asserted-by":"publisher","first-page":"292","DOI":"10.2174\/1568026619666190122152957","volume":"19","author":"M Merlani","year":"2019","unstructured":"Merlani M, Barbakadze V, Amiranashvili L, Gogilashvili L, Poroikov V, Petrou A, Geronikaki A, Ciric A, Glamoclija J, Sokovic M (2019) New caffeic acid derivatives as antimicrobial agents: design, synthesis, evaluation and docking. Curr Top Med Chem 19:292\u2013304. https:\/\/doi.org\/10.2174\/1568026619666190122152957","journal-title":"Curr Top Med Chem"},{"key":"814_CR6","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1111\/jam.13540","volume":"123","author":"J Morales","year":"2017","unstructured":"Morales J, Mendoza L, Cotoras M (2017) Alteration of oxidative phosphorylation as a possible mechanism of the antifungal action of p-coumaric acid against Botrytis cinerea. J Appl Microbiol 123:969\u2013976. https:\/\/doi.org\/10.1111\/jam.13540","journal-title":"J Appl Microbiol"},{"key":"814_CR7","doi-asserted-by":"publisher","unstructured":"Nakasu CCT, Waller SB, Ripoll MK, Ferreira MRA, Concei\u00e7\u00e3o FR, Gomes AR, Os\u00f3rio LG, de Faria RO, Cleff MB (2020) Feline sporotrichosis: a case series of itraconazole-resistant Sporothrix brasiliensis infection. Braz J Microbiol. https:\/\/doi.org\/10.1007\/s42770-020-00290-5","DOI":"10.1007\/s42770-020-00290-5"},{"key":"814_CR8","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1186\/1471-2334-14-219","volume":"14","author":"AM Rodrigues","year":"2014","unstructured":"Rodrigues AM, de Hoog GS, Pires DC, Brilhante RS, Sidrim JJ, Gadelha MF, Colombo AL, de Camargo ZP (2014) Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis. BMC Infect Dis 14:219. https:\/\/doi.org\/10.1186\/1471-2334-14-219","journal-title":"BMC Infect Dis"},{"key":"814_CR9","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1016\/j.bmcl.2016.01.040","volume":"26","author":"MT Varela","year":"2016","unstructured":"Varela MT, Dias RZ, Martins LF, Ferreira DD, Tempone AG, Ueno AK, Lago JHG, Fernandes JPS (2016) Gibbilimbol analogues as antiparasitic agents\u2014synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum. Bioorg Med Chem Lett 26:1180\u20131183. https:\/\/doi.org\/10.1016\/j.bmcl.2016.01.040","journal-title":"Bioorg Med Chem Lett"},{"key":"814_CR10","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1111\/cbdd.12986","volume":"90","author":"MT Varela","year":"2017","unstructured":"Varela MT, Lima ML, Galuppo MK, Tempone AG, de Oliveira A, Lago JHG, Fernandes JPS (2017) New alkenyl derivative from Piper malacophyllum and analogues: antiparasitic activity against Trypanosoma cruzi and Leishmania infantum. Chem Biol Drug Des 90:1007\u20131011. https:\/\/doi.org\/10.1111\/cbdd.12986","journal-title":"Chem Biol Drug Des"},{"key":"814_CR11","doi-asserted-by":"publisher","first-page":"102996","DOI":"10.1016\/j.bioorg.2019.102996","volume":"89","author":"MT Varela","year":"2019","unstructured":"Varela MT, Costa-Silva TA, Lago JHG, Tempone AG, Fernandes JPS (2019) Evaluation of the antitrypanosoma activity and SAR study of novel LINS03 derivatives. Bioorg Chem 89:102996. https:\/\/doi.org\/10.1016\/j.bioorg.2019.102996","journal-title":"Bioorg Chem"},{"key":"814_CR12","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1099\/jmm.0.000517","volume":"66","author":"SB Waller","year":"2017","unstructured":"Waller SB, Madrid IM, Hoffmann JF, Picoli T, Cleff MB, Chaves FC, de Faria RO, Meireles MCA, de Mello JRB (2017) Chemical composition and cytotoxicity of extracts of marjoram and rosemary and their activity against Sporothrix brasiliensis. J Med Microbiol 66:1076\u20131083. https:\/\/doi.org\/10.1099\/jmm.0.000517","journal-title":"J Med Microbiol"},{"key":"814_CR13","doi-asserted-by":"publisher","first-page":"e17858","DOI":"10.1590\/s2175-97902018000417858","volume":"54","author":"SB Waller","year":"2018","unstructured":"Waller SB, Nakasu C, Silva AL, de Faria RO, Fernandes JPS, Cleff MB (2018) Anti-Sporothrix brasiliensis activity of different pyrazinoic acid prodrugs: a repurposing evaluation. Braz J Pharm Sci 54:e17858. https:\/\/doi.org\/10.1590\/s2175-97902018000417858","journal-title":"Braz J Pharm Sci"},{"key":"814_CR14","doi-asserted-by":"publisher","unstructured":"Waller SB, Cleff MB, de Mattos CB, da Silva CC, Giordani C, Dalla Lana DF, Fuentefria AM, Freitag RA, Sallis ESV, de Mello JRB, de Faria RO, Meireles MCA (2019) In vivo protection of the marjoram (Origanum majorana Linn.) essential oil in the cutaneous sporotrichosis by Sporothrix brasiliensis. Nat Prod Res. https:\/\/doi.org\/10.1080\/14786419.2019.1678617","DOI":"10.1080\/14786419.2019.1678617"},{"key":"814_CR15","doi-asserted-by":"publisher","unstructured":"Waller SB, Ripoll MK, Madrid IM, Acunha T, Cleff MB, Chaves FC, de Mello JRB, de Faria RO, Meireles MCA (2020a) Susceptibility and resistance of Sporothrix brasiliensis to branded and compounded itraconazole formulations. Braz J Microbiol. https:\/\/doi.org\/10.1007\/s42770-020-00280-7","DOI":"10.1007\/s42770-020-00280-7"},{"key":"814_CR16","doi-asserted-by":"publisher","unstructured":"Waller SB, Dalla Lana DF, Quatrin PM, Ferreira MRA, Fuentefria AM, Mezzari A (2020b) Antifungal resistance on Sporothrix species: an overview. Braz J Microbiol. https:\/\/doi.org\/10.1007\/s42770-020-00307-z","DOI":"10.1007\/s42770-020-00307-z"}],"container-title":["Folia Microbiologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12223-020-00814-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12223-020-00814-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12223-020-00814-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T23:17:29Z","timestamp":1629501449000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12223-020-00814-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,21]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["814"],"URL":"https:\/\/doi.org\/10.1007\/s12223-020-00814-4","relation":{},"ISSN":["0015-5632","1874-9356"],"issn-type":[{"type":"print","value":"0015-5632"},{"type":"electronic","value":"1874-9356"}],"subject":[],"published":{"date-parts":[[2020,8,21]]},"assertion":[{"value":"25 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that no experiments were performed on humans or animals for this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Protection of human and animal subjects"}},{"value":"The authors declare that no patient data appear in this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Confidentiality of data"}},{"value":"The authors declare that no patient data appear in this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Right to privacy and informed consent"}},{"value":"The authors declare that they have no conflicts of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}