{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T03:49:24Z","timestamp":1786506564752,"version":"build-2736575974"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T00:00:00Z","timestamp":1532995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virol. Sin."],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1007\/s12250-018-0044-z","type":"journal-article","created":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T15:20:30Z","timestamp":1533050430000},"page":"323-334","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Serological Investigation of Laboratory-Confirmed and Suspected Ebola Virus Disease Patients During the Late Phase of the Ebola Outbreak in Sierra Leone"],"prefix":"10.1016","volume":"33","author":[{"given":"Yang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YuLan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AQian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XianDa","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QiuDong","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ShaoJian","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DaPeng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HaiYang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiuXu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idrissa","family":"Kamara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheku","family":"Koroma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Bangura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alie","family":"Tia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Kamara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matt","family":"Lebby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brima","family":"Kargbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiandong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiwen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiaoPing","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YueLong","family":"Shu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WenBo","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George F.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GuiZhen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DeXin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0317-9467","authenticated-orcid":false,"given":"William J.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3411-3014","authenticated-orcid":false,"given":"MiFang","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","published-online":{"date-parts":[[2018,7,31]]},"reference":[{"key":"44_CR1","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1128\/JCM.01979-16","volume":"55","author":"A Ayouba","year":"2017","unstructured":"Ayouba A, Toure A, Butel C, Keita AK, Binetruy F, Sow MS, Foulongne V, Delaporte E, Peeters M (2017) Development of a sensitive and specific serological assay based on Luminex technology for detection of antibodies to Zaire Ebola virus. J Clin Microbiol 55:165\u2013176","journal-title":"J Clin Microbiol"},{"key":"44_CR2","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1056\/NEJMoa1404505","volume":"371","author":"S Baize","year":"2014","unstructured":"Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, Magassouba N, Soropogui B, Sow MS, Keita S, De Clerck H, Tiffany A, Dominguez G, Loua M, Traore A, Kolie M, Malano ER, Heleze E, Bocquin A, Mely S, Raoul H, Caro V, Cadar D, Gabriel M, Pahlmann M, Tappe D, Schmidt-Chanasit J, Impouma B, Diallo AK, Formenty P, Van Herp M, Gunther S (2014) Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med 371:1418\u20131425","journal-title":"N Engl J Med"},{"key":"44_CR3","doi-asserted-by":"publisher","first-page":"e1600378","DOI":"10.1126\/sciadv.1600378","volume":"2","author":"DJ Blackley","year":"2016","unstructured":"Blackley DJ, Wiley MR, Ladner JT, Fallah M, Lo T, Gilbert ML, Gregory C, D\u2019Ambrozio J, Coulter S, Mate S, Balogun Z, Kugelman J, Nwachukwu W, Prieto K, Yeiah A, Amegashie F, Kearney B, Wisniewski M, Saindon J, Schroth G, Fakoli L, Diclaro JW 2nd, Kuhn JH, Hensley LE, Jahrling PB, Stroher U, Nichol ST, Massaquoi M, Kateh F, Clement P, Gasasira A, Bolay F, Monroe SS, Rambaut A, Sanchez-Lockhart M, Scott Laney A, Nyenswah T, Christie A, Palacios G (2016) Reduced evolutionary rate in reemerged Ebola virus transmission chains. Sci Adv 2:e1600378","journal-title":"Sci Adv"},{"key":"44_CR4","doi-asserted-by":"publisher","first-page":"160133","DOI":"10.1038\/sdata.2016.133","volume":"4","author":"H Bower","year":"2017","unstructured":"Bower H, Glynn JR (2017) A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection. Sci Data 4:160133","journal-title":"Sci Data"},{"key":"44_CR5","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1128\/CMR.00003-16","volume":"29","author":"MJ Broadhurst","year":"2016","unstructured":"Broadhurst MJ, Brooks TJ, Pollock NR (2016) Diagnosis of Ebola virus disease: past, Present, and Future. Clin Microbiol Rev 29:773\u2013793","journal-title":"Clin Microbiol Rev"},{"key":"44_CR6","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1677\/jme.1.01755","volume":"34","author":"SA Bustin","year":"2005","unstructured":"Bustin SA, Benes V, Nolan T, Pfaffl MW (2005) Quantitative real-time RT-PCR-a perspective. J Mol Endocrinol 34:597\u2013601","journal-title":"J Mol Endocrinol"},{"key":"44_CR7","doi-asserted-by":"publisher","first-page":"4421","DOI":"10.1172\/JCI83162","volume":"125","author":"MA Vega de La","year":"2015","unstructured":"de La Vega MA, Caleo G, Audet J, Qiu X, Kozak RA, Brooks JI, Kern S, Wolz A, Sprecher A, Greig J, Lokuge K, Kargbo DK, Kargbo B, Di Caro A, Grolla A, Kobasa D, Strong JE, Ippolito G, Van Herp M, Kobinger GP (2015) Ebola viral load at diagnosis associates with patient outcome and outbreak evolution. J Clin Invest 125:4421\u20134428","journal-title":"J Clin Invest"},{"key":"44_CR8","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1093\/cid\/ciw114","volume":"62","author":"NE Dean","year":"2016","unstructured":"Dean NE, Halloran ME, Yang Y, Longini IM (2016) Transmissibility and pathogenicity of ebola virus: a systematic review and meta-analysis of household secondary attack rate and asymptomatic infection. Clin Infect Dis 62:1277\u20131286","journal-title":"Clin Infect Dis"},{"key":"44_CR9","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1056\/NEJMoa1511410","volume":"377","author":"GF Deen","year":"2017","unstructured":"Deen GF, Broutet N, Xu W, Knust B, Sesay FR, McDonald SLR, Ervin E, Marrinan JE, Gaillard P, Habib N, Liu H, Liu W, Thorson AE, Yamba F, Massaquoi TA, James F, Ariyarajah A, Ross C, Bernstein K, Coursier A, Klena J, Carino M, Wurie AH, Zhang Y, Dumbuya MS, Abad N, Idriss B, Wi T, Bennett SD, Davies T, Ebrahim FK, Meites E, Naidoo D, Smith SJ, Ongpin P, Malik T, Banerjee A, Erickson BR, Liu Y, Liu Y, Xu K, Brault A, Durski KN, Winter J, Sealy T, Nichol ST, Lamunu M, Bangura J, Landoulsi S, Jambai A, Morgan O, Wu G, Liang M, Su Q, Lan Y, Hao Y, Formenty P, Stroher U, Sahr F (2017) Ebola RNA persistence in semen of Ebola virus disease survivors\u2014final report. N Engl J Med 377:1428\u20131437","journal-title":"N Engl J Med"},{"key":"44_CR10","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1126\/science.346.6209.666","volume":"346","author":"GF Gao","year":"2014","unstructured":"Gao GF, Feng Y (2014) On the ground in Sierra Leone. Science 346:666","journal-title":"Science"},{"key":"44_CR11","doi-asserted-by":"publisher","first-page":"20160308","DOI":"10.1098\/rstb.2016.0308","volume":"372","author":"T Garske","year":"2017","unstructured":"Garske T, Cori A, Ariyarajah A, Blake IM, Dorigatti I, Eckmanns T, Fraser C, Hinsley W, Jombart T, Mills HL, Nedjati-Gilani G, Newton E, Nouvellet P, Perkins D, Riley S, Schumacher D, Shah A, Van Kerkhove MD, Dye C, Ferguson NM, Donnelly CA (2017) Heterogeneities in the case fatality ratio in the West African Ebola outbreak 2013-2016. Philos Trans R Soc Lond B Biol Sci 372:20160308","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"44_CR12","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/S1473-3099(17)30111-1","volume":"17","author":"JR Glynn","year":"2017","unstructured":"Glynn JR, Bower H, Johnson S, Houlihan CF, Montesano C, Scott JT, Semple MG, Bangura MS, Kamara AJ, Kamara O, Mansaray SH, Sesay D, Turay C, Dicks S, Wadoum REG, Colizzi V, Checchi F, Samuel D, Tedder RS (2017) Asymptomatic infection and unrecognised Ebola virus disease in Ebola-affected households in Sierra Leone: a cross-sectional study using a new non-invasive assay for antibodies to Ebola virus. Lancet Infect Dis 17:645\u2013653","journal-title":"Lancet Infect Dis"},{"key":"44_CR13","first-page":"945","volume-title":"Fields virology, Chapter 32","author":"F Heinz","year":"2013","unstructured":"Heinz F, Anthony S, Thoms G (2013) Filoviridae: Marburg and Ebola viruses. In: Knipe D, Howley P (eds) Fields virology, Chapter 32, 6th edn. Williams and Wilkins, Baltimore, pp 945\u2013947","edition":"6"},{"issue":"Suppl 1","key":"44_CR14","doi-asserted-by":"publisher","first-page":"S192","DOI":"10.1086\/514313","volume":"179","author":"TG Ksiazek","year":"1999","unstructured":"Ksiazek TG, West CP, Rollin PE, Jahrling PB, Peters CJ (1999) ELISA for the detection of antibodies to Ebola viruses. J Infect Dis 179(Suppl 1):S192\u2013198","journal-title":"J Infect Dis"},{"key":"44_CR15","doi-asserted-by":"publisher","first-page":"2415","DOI":"10.1373\/clinchem.2005.051532","volume":"51","author":"RM Lequin","year":"2005","unstructured":"Lequin RM (2005) Enzyme immunoassay (EIA)\/enzyme-linked immunosorbent assay (ELISA). Clin Chem 51:2415\u20132418","journal-title":"Clin Chem"},{"key":"44_CR16","doi-asserted-by":"publisher","first-page":"2210","DOI":"10.1016\/S0140-6736(00)02405-3","volume":"355","author":"EM Leroy","year":"2000","unstructured":"Leroy EM, Baize S, Volchkov VE, Fisher-Hoch SP, Georges-Courbot MC, Lansoud-Soukate J, Capron M, Debre P, McCormick JB, Georges AJ (2000) Human asymptomatic Ebola infection and strong inflammatory response. Lancet 355:2210\u20132215","journal-title":"Lancet"},{"key":"44_CR17","first-page":"321","volume":"28","author":"A Li","year":"2014","unstructured":"Li A, Li W, Li J, Zhang S, Qu J, Li C, Zhang Q, Liang M, Li D (2014) Development of real-time RT-PCR assay for detection of Zaire Ebolavirus. Chin J Exp Clin Virol 28:321\u2013323 (in Chinese)","journal-title":"Chin J Exp Clin Virol"},{"key":"44_CR18","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.3201\/eid2111.150582","volume":"21","author":"HJ Lu","year":"2015","unstructured":"Lu HJ, Qian J, Kargbo D, Zhang XG, Yang F, Hu Y, Sun Y, Cao YX, Deng YQ, Su HX, Dafae F, Sun Y, Wang CY, Nie WM, Bai CQ, Xia ZP, Liu K, Kargbo B, Gao GF, Jiang JF (2015) Ebola Virus Outbreak Investigation, Sierra Leone, September 28-November 11, 2014. Emerg Infect Dis 21:1921\u20131927","journal-title":"Emerg Infect Dis"},{"key":"44_CR19","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S0166-0934(03)00131-9","volume":"111","author":"A Lucht","year":"2003","unstructured":"Lucht A, Grunow R, Moller P, Feldmann H, Becker S (2003) Development, characterization and use of monoclonal VP40-antibodies for the detection of Ebola virus. J Virol Methods 111:21\u201328","journal-title":"J Virol Methods"},{"key":"44_CR20","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s00430-003-0204-z","volume":"193","author":"A Lucht","year":"2004","unstructured":"Lucht A, Grunow R, Otterbein C, Moller P, Feldmann H, Becker S (2004) Production of monoclonal antibodies and development of an antigen capture ELISA directed against the envelope glycoprotein GP of Ebola virus. Med Microbiol Immunol 193:181\u2013187","journal-title":"Med Microbiol Immunol"},{"key":"44_CR21","doi-asserted-by":"publisher","first-page":"3267","DOI":"10.1128\/JCM.39.9.3267-3271.2001","volume":"39","author":"M Niikura","year":"2001","unstructured":"Niikura M, Ikegami T, Saijo M, Kurane I, Miranda ME, Morikawa S (2001) Detection of Ebola viral antigen by enzyme-linked immunosorbent assay using a novel monoclonal antibody to nucleoprotein. J Clin Microbiol 39:3267\u20133271","journal-title":"J Clin Microbiol"},{"key":"44_CR22","doi-asserted-by":"publisher","first-page":"e95635","DOI":"10.1371\/journal.pone.0095635","volume":"9","author":"Z Pang","year":"2014","unstructured":"Pang Z, Li A, Li J, Qu J, He C, Zhang S, Li C, Zhang Q, Liang M, Li D (2014) Comprehensive multiplex one-step real-time TaqMan qRT-PCR assays for detection and quantification of hemorrhagic fever viruses. PLoS ONE 9:e95635","journal-title":"PLoS ONE"},{"key":"44_CR23","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.jcv.2015.01.014","volume":"64","author":"V Rougeron","year":"2015","unstructured":"Rougeron V, Feldmann H, Grard G, Becker S, Leroy EM (2015) Ebola and Marburg haemorrhagic fever. J Clin Virol 64:111\u2013119","journal-title":"J Clin Virol"},{"key":"44_CR24","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.3201\/eid2007.131265","volume":"20","author":"RJ Schoepp","year":"2014","unstructured":"Schoepp RJ, Rossi CA, Khan SH, Goba A, Fair JN (2014) Undiagnosed acute viral febrile illnesses, Sierra Leone. Emerg Infect Dis 20:1176\u20131182","journal-title":"Emerg Infect Dis"},{"key":"44_CR25","doi-asserted-by":"publisher","first-page":"2956","DOI":"10.1128\/JCM.01317-15","volume":"53","author":"TR Southern","year":"2015","unstructured":"Southern TR, Racsa LD, Albarino CG, Fey PD, Hinrichs SH, Murphy CN, Herrera VL, Sambol AR, Hill CE, Ryan EL, Kraft CS, Campbell S, Sealy TK, Schuh A, Ritchie JC, Lyon GM 3rd, Mehta AK, Varkey JB, Ribner BS, Brantly KP, Stroher U, Iwen PC, Burd EM (2015) Comparison of filmarray and quantitative real-time reverse transcriptase pcr for detection of Zaire Ebolavirus from contrived and clinical specimens. J Clin Microbiol 53:2956\u20132960","journal-title":"J Clin Microbiol"},{"key":"44_CR26","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1093\/infdis\/jiw078","volume":"214","author":"MS Sow","year":"2016","unstructured":"Sow MS, Etard JF, Baize S, Magassouba N, Faye O, Msellati P, Toure A 2nd, Savane I, Barry M, Delaporte E (2016) New evidence of long-lasting persistence of Ebola virus genetic material in semen of survivors. J Infect Dis 214:1475\u20131476","journal-title":"J Infect Dis"},{"key":"44_CR27","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1056\/NEJMoa1504874","volume":"374","author":"TM Uyeki","year":"2016","unstructured":"Uyeki TM, Mehta AK, Davey RT Jr, Liddell AM, Wolf T, Vetter P, Schmiedel S, Grunewald T, Jacobs M, Arribas JR, Evans L, Hewlett AL, Brantsaeter AB, Ippolito G, Rapp C, Hoepelman AI, Gutman J (2016) Clinical management of Ebola virus disease in the United States and Europe. N Engl J Med 374:636\u2013646","journal-title":"N Engl J Med"},{"key":"44_CR28","doi-asserted-by":"publisher","first-page":"2423","DOI":"10.1056\/NEJMoa1500306","volume":"372","author":"JB Varkey","year":"2015","unstructured":"Varkey JB, Shantha JG, Crozier I, Kraft CS, Lyon GM, Mehta AK, Kumar G, Smith JR, Kainulainen MH, Whitmer S, Stroher U, Uyeki TM, Ribner BS, Yeh S (2015) Persistence of Ebola virus in ocular fluid during convalescence. N Engl J Med 372:2423\u20132427","journal-title":"N Engl J Med"},{"key":"44_CR29","first-page":"210","volume":"32","author":"Q Wang","year":"2016","unstructured":"Wang Q, Zhang Y, Nie K, Wang H, Du H, Song J, Xiao K, Lei W, Guo J, Wei H, Cai K, Wang Y, Wu J, Gerald B, Kamara IL, Liang M, Wu G, Dong X (2016) Establishment of quality control system of nucleic acid detection for ebola virus in sierra leone-china friendship biological safety laboratory. Bing du xue bao 32:210\u2013214 (in Chinese)","journal-title":"Bing du xue bao"},{"key":"44_CR31","unstructured":"WHO (2016) Situation report: Ebola virus disease. Accessed 30 March 2016"},{"key":"44_CR32","unstructured":"WHO (2016) Statement on the 9th meeting of the IHR Emergency Committee regarding the Ebola outbreak in West Africa. 29 March 2016"},{"key":"44_CR33","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.virusres.2013.12.037","volume":"187","author":"W Wu","year":"2014","unstructured":"Wu W, Zhang S, Qu J, Zhang Q, Li C, Li J, Jin C, Liang M, Li D (2014) Simultaneous detection of IgG antibodies associated with viral hemorrhagic fever by a multiplexed Luminex-based immunoassay. Virus Res 187:84\u201390","journal-title":"Virus Res"},{"key":"44_CR34","first-page":"14","volume":"32","author":"R Zhou","year":"2016","unstructured":"Zhou R, Sun L, Liu Y, Wu W, Li C, Liang M, Qiu P (2016) Research of human-mouse chimeric antibodies against ebola virus nucleoprotein. Bing du xue bao 32:14\u201318 (in Chinese)","journal-title":"Bing du xue bao"}],"container-title":["Virologica Sinica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12250-018-0044-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12250-018-0044-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12250-018-0044-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T06:40:23Z","timestamp":1641278423000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12250-018-0044-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,31]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["44"],"URL":"https:\/\/doi.org\/10.1007\/s12250-018-0044-z","relation":{},"ISSN":["1674-0769","1995-820X"],"issn-type":[{"value":"1674-0769","type":"print"},{"value":"1995-820X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,31]]},"assertion":[{"value":"30 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 June 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study did not involve human experimentation, and all the blood samples were collected from Ebola patients with prior consent of the Ministry of Health and Sanitation of Sierra Leone. Biosafety evaluations were approved by the National Institute for Viral Disease Control and Prevention, China CDC. All experimental operations were handled following the Standard Operational Protocol approved by China CDC.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal and Human Rights Statement"}}]}}