{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:35:42Z","timestamp":1792190142949,"version":"4.4.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T00:00:00Z","timestamp":1450396800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Scientific Research Fund of Antalya Training and Research Hospital","award":["2013-117082"],"award-info":[{"award-number":["2013-117082"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pathol. Oncol. Res."],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1007\/s12253-015-0031-8","type":"journal-article","created":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T08:10:23Z","timestamp":1450426223000},"page":"515-521","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Immunohistochemical Analysis of E-Cadherin, p53 and Inhibin-\u03b1 Expression in Hydatidiform Mole and Hydropic Abortion"],"prefix":"10.1007","volume":"22","author":[{"given":"Onur","family":"Erol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Din\u00e7","family":"S\u00fcren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birsel","family":"Tutu\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tayfun","family":"Topta\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Arda","family":"G\u00f6kay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysel Uysal","family":"Derbent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa Kemal","family":"\u00d6zel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cem","family":"Sezer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,18]]},"reference":[{"key":"31_CR1","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S1521-6934(03)00094-4","volume":"17","author":"AN Cheung","year":"2003","unstructured":"Cheung AN (2003) Pathology of gestational trophoblastic disease. Baillieres Best Pract Res Clin Obstet Gynaecol 17:849\u2013868","journal-title":"Baillieres Best Pract. Res. Clin. Obstet. Gynaecol"},{"key":"31_CR2","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1097\/01.pas.0000157996.23059.c1","volume":"29","author":"M Fukunaga","year":"2005","unstructured":"Fukunaga M, Katabuchi H, Nagasaka T, Mikami Y, Minamiguchi S, Lage JM (2005) Interobserver and intraobserver variability in the diagnosis of hydatidiform mole. Am J Surg Pathol 29:942\u2013947","journal-title":"Am J Surg Pathol"},{"key":"31_CR3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.1365-2559.2003.01667.x","volume":"43","author":"SY Jun","year":"2003","unstructured":"Jun SY, Ro JY, Kim KR (2003) P57kip2 is useful in the classification and differential diagnosis of complete and partial hydatidiform moles. Histopathology 43:17\u201325","journal-title":"Histopathology"},{"key":"31_CR4","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1530\/ror.0.0050053","volume":"5","author":"TM Rowlands","year":"2000","unstructured":"Rowlands TM, Symonds JM, Farookhi R, Blaschuk OW (2000) Cadherins: crucial regulators of structure and function in reproductive tissues. Rev Reprod 5:53\u201361","journal-title":"Rev Reprod"},{"key":"31_CR5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s12253-008-9132-y","volume":"15","author":"W Yuan","year":"2009","unstructured":"Yuan W, Chen Z, Wu S, Ge J, Chang S, Wang X, Chen J, Chen Z (2009) Expression of EphA2 and E-cadherin in gastric cancer: correlated with tumor progression and lymphogenous metastasis. Pathol Oncol Res 15:473\u2013478","journal-title":"Pathol Oncol Res"},{"key":"31_CR6","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.bbrc.2005.03.190","volume":"331","author":"T Soussi","year":"2005","unstructured":"Soussi T, Lozano G (2005) p53 mutation heterogeneity in cancer. Biochem Biophys Res Commun 331:834\u2013842","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"31_CR7","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/1044-7431(91)90012-D","volume":"2","author":"PS Lapolt","year":"1991","unstructured":"Lapolt PS, Hsueh AJW (1991) Moleculer basis of inhibin production and action. Mol Cell Neurosci 2:449\u2013463","journal-title":"Mol Cell Neurosci"},{"key":"31_CR8","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/106689699800600301","volume":"6","author":"X Matias-Guiu","year":"1998","unstructured":"Matias-Guiu X, Lerma E, Prat J (1998) Current topics in pathology of gynecologic tumors: a selective review. Int J Surg Pathol 6:121\u2013134","journal-title":"Int J Surg Pathol"},{"key":"31_CR9","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.tem.2009.11.009","volume":"21","author":"KL Stenvers","year":"2010","unstructured":"Stenvers KL, Findlay JK (2010) Inhibins: from reproductive hormones to tumor suppressors. Trends Endocrinol Metab 21:174\u2013180","journal-title":"Trends Endocrinol Metab"},{"key":"31_CR10","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1080\/00313020601137367","volume":"39","author":"M Wells","year":"2007","unstructured":"Wells M (2007) The pathology of gestational trophoblastic disease: recent advances. Pathology 39:88\u201396","journal-title":"Pathology"},{"key":"31_CR11","doi-asserted-by":"crossref","first-page":"598","DOI":"10.2353\/jmoldx.2009.090039","volume":"11","author":"KM Murphy","year":"2009","unstructured":"Murphy KM, Mc Connell TG, Hafez MJ, Vang R, Ronnett BM (2009) Molecular genotyping of hydatidiform moles: analytic validation of a multiplex short tandem repeat assay. J Mol Diagn 11:598\u2013605","journal-title":"J Mol Diagn"},{"key":"31_CR12","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.yexmp.2009.03.005","volume":"87","author":"MR Hussein","year":"2009","unstructured":"Hussein MR (2009) Analysis of p53, BCL-2 and epidermal growth factor receptor protein expression in the partial and complete hydatidiform moles. Exp Mol Pathol 87:63\u201369","journal-title":"Exp Mol Pathol"},{"key":"31_CR13","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/01.AOG.0000224697.31138.a1","volume":"108","author":"JT Soper","year":"2006","unstructured":"Soper JT (2006) Gestational trophoblastic disease. Obstet Gynecol 108:176\u2013187","journal-title":"Obstet Gynecol"},{"key":"31_CR14","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1055\/s-2000-12562","volume":"18","author":"SJ Kimber","year":"2000","unstructured":"Kimber SJ (2000) Molecular interactions at the maternal-embryonic interface during the early phase of implantation. Semin Reprod Med 18:237\u2013253","journal-title":"Semin Reprod Med"},{"key":"31_CR15","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1093\/molehr\/6.10.943","volume":"6","author":"C Floridon","year":"2000","unstructured":"Floridon C, Nielsen O, Holund B, Sunde L, Westergaard JG, Thomsen SG, Teisner B (2000) Localization of E-cadherin in villous, extravillous and vascular trophoblasts during intrauterine, ectopic and molar pregnancy. Mol Hum Reprod 6:943\u2013950","journal-title":"Mol Hum Reprod"},{"key":"31_CR16","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00418-005-0051-7","volume":"124","author":"LM Brown","year":"2005","unstructured":"Brown LM, Lacey HA, Baker PN, Crocker IP (2005) E-cadherin in the assessment of aberrant placental cytotrophoblast turnover in pregnancies complicated by preeclampsia. Histochem Cell Biol 124:499\u2013506","journal-title":"Histochem Cell Biol"},{"key":"31_CR17","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.placenta.2006.09.004","volume":"28","author":"A Batistatou","year":"2007","unstructured":"Batistatou A, Makrydimas G, Zagorianakou N, Zagorianakou P, Nakanishi Y, Agnantis NJ, Hirohashi S, Charalabopoulos K (2007) Expression of dysadherin and E-cadherin in trophoblastic tissue in normal and abnormal pregnancies. Placenta 28:590\u2013592","journal-title":"Placenta"},{"key":"31_CR18","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1097\/IGC.0b013e31827da23f","volume":"23","author":"H Shu","year":"2013","unstructured":"Shu H, Chen H, Yang B, Chang Z, Xiong M, Chen W (2013) Aberrant expression of E-cadherin and integrin \u03b2-1 in trophoblasts is associated with malignant gestational trophoblastic diseases. Int J Gynecol Cancer 23:749\u2013754","journal-title":"Int J Gynecol Cancer"},{"key":"31_CR19","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1111\/j.1525-1438.2003.13400.x","volume":"13","author":"WC Xue","year":"2003","unstructured":"Xue WC, Feng HC, Tsao SW, Chan KY, Ngan HY, Chiu PM, Maccalman CD, Cheung AN (2003) Methylation status and expression of E-cadherin and cadherin-11 in gestational trophoblastic diseases. Int J Gynecol Cancer 13:879\u2013888","journal-title":"Int J Gynecol Cancer"},{"key":"31_CR20","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1111\/j.1048-891x.2004.014316.x","volume":"14","author":"P Balaram","year":"2004","unstructured":"Balaram P, Alex S, Panikkar B, Rajalekshmi TN (2004) Adhesion-related proteins E-cadherin, P-cadherin, CD44, and CD44v6, and antimetastatic protein nm23H1 in complete hydatidiform moles in relation to invasion potential. Int J Gynecol Cancer 14:532\u2013539","journal-title":"Int J Gynecol Cancer"},{"key":"31_CR21","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/molehr\/gal105","volume":"13","author":"M Cohen","year":"2007","unstructured":"Cohen M, Meisser A, Haenggeli L, Irminger-Finger I, Bischof P (2007) Status of p53 in first-trimester cytotrophoblastic cells. Mol Hum Reprod 13:111\u2013116","journal-title":"Mol Hum Reprod"},{"key":"31_CR22","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0143-4004(95)90086-1","volume":"16","author":"K Marzusch","year":"1995","unstructured":"Marzusch K, Ruck P, Horny HP, Dietl J, Kaiserling E (1995) Expression of the p53 tumour suppressor gene in human placenta: an immunohistochemical study. Placenta 16:101\u2013104","journal-title":"Placenta"},{"key":"31_CR23","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1053\/plac.1999.0442","volume":"21","author":"R Halperin","year":"2000","unstructured":"Halperin R, Peller S, Sandbank J, Bukovsky I, Schneider D (2000) Expression of the p53 gene and apoptosis in gestational trophoblastic disease. Placenta 21:58\u201362","journal-title":"Placenta"},{"key":"31_CR24","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1067\/mob.2001.111243","volume":"184","author":"A Kale","year":"2001","unstructured":"Kale A, S\u00f6ylemez F, Ensari A (2001) Expressions of proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein in gestational trophoblastic disease. Am J Obstet Gynecol 184:567\u2013574","journal-title":"Am J Obstet Gynecol"},{"key":"31_CR25","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1111\/j.1525-1438.2006.00643.x","volume":"16","author":"P Petignat","year":"2006","unstructured":"Petignat P, Laurini R, Goffin F, Bruchim I, Bischof P (2006) Expression of matrix metalloproteinase-2 and mutant p53 is increased in hydatidiform mole as compared with normal placenta. Int J Gynecol Cancer 16:1679\u20131684","journal-title":"Int J Gynecol Cancer"},{"key":"31_CR26","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1034\/j.1600-0463.2000.d01-25.x","volume":"108","author":"IA Al-Bozom","year":"2000","unstructured":"Al-Bozom IA (2000) p53 and Bcl-2 oncoprotein expression in placentas with hydropic changes and partial and complete moles. APMIS 108:756\u2013760","journal-title":"APMIS"},{"key":"31_CR27","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s00508-011-0119-4","volume":"124","author":"Y Chen","year":"2012","unstructured":"Chen Y, Shen D, Gu Y, Zhong P, Xie J, Song Q (2012) The diagnostic value of Ki-67, P53 and P63 in distinguishing partial hydatidiform mole from hydropic abortion. Wien Klin Wochenschr 124:184\u2013187","journal-title":"Wien Klin Wochenschr"},{"key":"31_CR28","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0143-4004(97)90065-5","volume":"18","author":"F Petraglia","year":"1997","unstructured":"Petraglia F (1997) Inhibin, activin, and follistatin in the human placenta: a new family of regulatory proteins. Placenta 18:3\u20138","journal-title":"Placenta"},{"key":"31_CR29","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s00418-004-0709-6","volume":"122","author":"I Mylonas","year":"2004","unstructured":"Mylonas I, Jeschke U, Wiest I, Hoeing A, Vogl J, Shabani N, Kuhn C, Schulze S, Kupka MS, Friese K (2004) Inhibin\/activinsubunits alpha, beta-A and beta-B are differentially expressed in normal human endometrium throughout the menstrual cycle. Histochem Cell Biol 122:461\u2013471","journal-title":"Histochem Cell Biol"},{"key":"31_CR30","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/humupd\/8.6.529","volume":"8","author":"DM Kretser de","year":"2002","unstructured":"de Kretser DM, HedgerMP LKL, Phillips DJ (2002) Inhibins, activins and follistatin in reproduction. Hum Reprod Update 8:529\u2013541","journal-title":"Hum Reprod Update"},{"key":"31_CR31","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1385\/EP:17:1:19","volume":"17","author":"I Mylonas","year":"2006","unstructured":"Mylonas I, Schiessl B, Jeschke U, Vogl J, Makrigiannakis A, Kuhn C, Schulze S, Kainer F, Friese K (2006) Expression of inhibin\/activin subunits alpha (\u2212alpha), betaA (\u2212betaA), and betaB (betaB) in placental tissue of normal, preeclamptic, and HELLP pregnancies. Endocr Pathol 17:19\u201333","journal-title":"Endocr Pathol"},{"key":"31_CR32","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00004347-199904000-00008","volume":"18","author":"IM Shih","year":"1999","unstructured":"Shih IM, Kurman RJ (1999) Immunohistochemical localization of inhibin-alpha in the placenta and gestational trophoblastic lesions. Int J Gynecol Pathol 18:144\u2013150","journal-title":"Int J Gynecol Pathol"},{"key":"31_CR33","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1097\/00004347-200110000-00011","volume":"20","author":"F Kommoss","year":"2001","unstructured":"Kommoss F, Schmidt D, Coerdt W, Olert J, M\u00fcntefering H (2001) Immunohistochemical expression analysis of inhibin-alpha and -beta subunits in partial and complete moles, trophoblastic tumors, and endometrial decidua. Int J Gynecol Pathol 20:380\u2013385","journal-title":"Int J Gynecol Pathol"},{"key":"31_CR34","first-page":"1995","volume":"27","author":"I Mylonas","year":"2007","unstructured":"Mylonas I, Shabani N, Vogl J, Makovitzky J, Kunze S, Kuhn C, Schulze S, Friese K, Jeschke U (2007) Inhibin\/activin subunits are immunohistochemically expressed in complete and partial hydatidiform moles. Anticancer Res 27:1995\u20132000","journal-title":"Anticancer Res"}],"container-title":["Pathology & Oncology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12253-015-0031-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12253-015-0031-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12253-015-0031-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T02:39:31Z","timestamp":1559443171000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12253-015-0031-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,18]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["31"],"URL":"https:\/\/doi.org\/10.1007\/s12253-015-0031-8","relation":{},"ISSN":["1219-4956","1532-2807"],"issn-type":[{"value":"1219-4956","type":"print"},{"value":"1532-2807","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,18]]}}}