{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T04:12:50Z","timestamp":1769746370668,"version":"3.49.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T00:00:00Z","timestamp":1543449600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772793\/H1621;31201060\/C0709;30973175\/C1701;81172490\/H1621"],"award-info":[{"award-number":["81772793\/H1621;31201060\/C0709;30973175\/C1701;81172490\/H1621"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004602","name":"Program for New Century Excellent Talents in University","doi-asserted-by":"publisher","award":["NCET-12-0440"],"award-info":[{"award-number":["NCET-12-0440"]}],"id":[{"id":"10.13039\/501100004602","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Scientific and Technological Research Foundation of Shaanxi Province","award":["2012K13-01-06"],"award-info":[{"award-number":["2012K13-01-06"]}]},{"name":"Research Foundation of Health Department of Shaanxi Province","award":["2010D41"],"award-info":[{"award-number":["2010D41"]}]},{"name":"Qing Nian Jiao Shi Gen Zong Ji Hua of Xi\u2019an Jiaotong University","award":["2012"],"award-info":[{"award-number":["2012"]}]},{"name":"Clinical Research Award of the First Affiliated Hospital of Xi'an Jiaotong University","award":["No. XJTU1AHCR2014-041"],"award-info":[{"award-number":["No. XJTU1AHCR2014-041"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pathol. Oncol. Res."],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1007\/s12253-018-0553-y","type":"journal-article","created":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T05:26:03Z","timestamp":1543469163000},"page":"521-531","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Endocrine Therapy for Ductal Carcinoma In Situ (DCIS) of the Breast with Breast Conserving Surgery (BCS) and Radiotherapy (RT): a Meta-Analysis"],"prefix":"10.1007","volume":"26","author":[{"given":"Yanli","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaxin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaofan","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zongfang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaozhi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel Kwateng","family":"Drokow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoting","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8360-8286","authenticated-orcid":false,"given":"Juan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,11,29]]},"reference":[{"key":"553_CR1","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1002\/jso.24184","volume":"113","author":"TA James","year":"2016","unstructured":"James TA, Wade JE, Sprague BL (2016) The impact of mammographic screening on the surgical management of breast cancer. J Surg Oncol 113:496\u2013500. \nhttps:\/\/doi.org\/10.1002\/jso.24184","journal-title":"J Surg Oncol"},{"key":"553_CR2","doi-asserted-by":"publisher","first-page":"182","DOI":"10.3322\/caac.21335","volume":"66","author":"LA Torre","year":"2016","unstructured":"Torre LA, Sauer AM, Chen MS Jr, Kagawa-Singer M, Jemal A, Siegel RL (2016) Cancer statistics for Asian Americans, native Hawaiians, and Pacific islanders, 2016: converging incidence in males and females. CA Cancer J Clin 66:182\u2013202. \nhttps:\/\/doi.org\/10.3322\/caac.21335","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"553_CR3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21332","volume":"66","author":"RL Siegel","year":"2016","unstructured":"Siegel RL, Miller KD, Jemal A (2016) Cancer statistics, 2016. CA Cancer J Clin 66(1):7\u201330. \nhttps:\/\/doi.org\/10.3322\/caac.21332","journal-title":"CA Cancer J Clin"},{"issue":"11","key":"553_CR4","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1007\/s11912-015-0473-x","volume":"17","author":"KB Mitchell","year":"2015","unstructured":"Mitchell KB, Kuerer H (2015) Ductal carcinoma in situ: treatment update and current trends. Curr Oncol Rep 17(11):48. \nhttps:\/\/doi.org\/10.1007\/s11912-015-0473-x","journal-title":"Curr Oncol Rep"},{"issue":"1","key":"553_CR5","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1097\/GCO.0000000000000237","volume":"28","author":"A Lebeau","year":"2016","unstructured":"Lebeau A, Kuhn T (2016) Updates in the treatment of ductal carcinoma in situ of the breast. Curr Opin Obstet Gynecol 28(1):49\u201358. \nhttps:\/\/doi.org\/10.1097\/GCO.0000000000000237","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"5","key":"553_CR6","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/j.breast.2014.06.015","volume":"23","author":"H Staley","year":"2014","unstructured":"Staley H, McCallum I, Bruce J (2014) Postoperative tamoxifen for ductal carcinoma in situ: Cochrane systematic review and meta-analysis. Breast (Edinburgh, Scotland) 23(5):546\u2013551. \nhttps:\/\/doi.org\/10.1016\/j.breast.2014.06.015","journal-title":"Breast (Edinburgh, Scotland)"},{"issue":"9378","key":"553_CR7","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0140-6736(03)13859-7","volume":"362","author":"J Houghton","year":"2003","unstructured":"Houghton J, George WD, Cuzick J, Duggan C, Fentiman IS, Spittle M (2003) Radiotherapy and tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled trial. Lancet 362(9378):95\u2013102","journal-title":"Lancet"},{"issue":"1","key":"553_CR8","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S1470-2045(10)70266-7","volume":"12","author":"J Cuzick","year":"2011","unstructured":"Cuzick J, Sestak I, Pinder SE, Ellis IO, Forsyth S, Bundred NJ, Forbes JF, Bishop H, Fentiman IS, George WD (2011) Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK\/ANZ DCIS trial. Lancet Oncol. 12(1):21\u201329. \nhttps:\/\/doi.org\/10.1016\/S1470-2045(10)70266-7","journal-title":"Lancet Oncol."},{"issue":"9324","key":"553_CR9","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.1016\/S0140-6736(02)09088-8","volume":"359","author":"M Baum","year":"2002","unstructured":"Baum M, Budzar AU, Cuzick J, Forbes J, Houghton JH, Klijn JG, Sahmoud T, Group AT (2002) Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 359(9324):2131\u20132139","journal-title":"Lancet"},{"issue":"9453","key":"553_CR10","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/S0140-6736(04)17666-6","volume":"365","author":"A Howell","year":"2005","unstructured":"Howell A, Cuzick J, Baum M, Buzdar A, Dowsett M, Forbes JF, Hoctin-Boes G, Houghton J, Locker GY, Tobias JS, Group AT (2005) Results of the ATAC (Arimidex, tamoxifen, alone or in combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 365(9453):60\u201362. \nhttps:\/\/doi.org\/10.1016\/S0140-6736(04)17666-6","journal-title":"Lancet"},{"issue":"26","key":"553_CR11","doi-asserted-by":"publisher","first-page":"2747","DOI":"10.1056\/NEJMoa052258","volume":"353","author":"B Thurlimann","year":"2005","unstructured":"Breast International Group 1-98 Collaborative G, Thurlimann B, Keshaviah A, Coates AS, Mouridsen H, Mauriac L, Forbes JF, Paridaens R, Castiglione-Gertsch M, Gelber RD, Rabaglio M, Smith I, Wardley A, Price KN, Goldhirsch A (2005) A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N Engl J Med 353(26):2747\u20132757. \nhttps:\/\/doi.org\/10.1056\/NEJMoa052258","journal-title":"N Engl J Med"},{"issue":"4","key":"553_CR12","first-page":"433","volume":"15","author":"WJ Gradishar","year":"2017","unstructured":"Gradishar WJ, Anderson BO, Balassanian R, Blair SL, Burstein HJ, Cyr A, Elias AD, Farrar WB, Forero A, Giordano SH (2017) NCCN guidelines insights: breast Cancer, version 1.2017. Journal of the National Comprehensive Cancer Network. Jnccn 15(4):433\u2013451","journal-title":"Jnccn"},{"key":"553_CR13","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/S0140-6736(15)01168-X","volume":"387","author":"RG Margolese","year":"2015","unstructured":"Margolese RG, Cecchini RS, Julian TB, Ganz PA, Costantino JP, Vallow LA, Albain KS, Whitworth PW, Cianfrocca ME, Brufsky AM, Gross HM, Soori GS, Hopkins JO, Fehrenbacher L, Sturtz K, Wozniak TF, Seay TE, Mamounas EP, Wolmark N (2015) Anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ undergoing lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial. Lancet 387:849\u2013856. \nhttps:\/\/doi.org\/10.1016\/S0140-6736(15)01168-X","journal-title":"Lancet"},{"key":"553_CR14","doi-asserted-by":"publisher","unstructured":"Forbes JF, Sestak I, Howell A, Bonanni B, Bundred N, Levy C, von Minckwitz G, Eiermann W, Neven P, Stierer M, Holcombe C, Coleman RE, Jones L, Ellis I, Cuzick J, investigators I-I (2015) Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial. Lancet. \nhttps:\/\/doi.org\/10.1016\/S0140-6736(15)01129-0","DOI":"10.1016\/S0140-6736(15)01129-0"},{"issue":"5","key":"553_CR15","first-page":"18","volume":"8","author":"KF S, DG A, D M, Group C","year":"2010","unstructured":"KF S, DG A, D M, Group C (2010) CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Ann Intern Med 8(5):18","journal-title":"Ann Intern Med"},{"key":"553_CR16","doi-asserted-by":"publisher","first-page":"2883","DOI":"10.2147\/OTT.S92259","volume":"8","author":"J Lu","year":"2015","unstructured":"Lu J, Zhao Q, Zhai YJ, He HR, Yang LH, Gao F, Zhou RS, Zheng J, Ma XC (2015) Genetic polymorphisms of CYP1A1 and risk of leukemia: a meta-analysis. OncoTargets Ther 8:2883\u20132902. \nhttps:\/\/doi.org\/10.2147\/OTT.S92259","journal-title":"OncoTargets Ther"},{"issue":"9169","key":"553_CR17","doi-asserted-by":"publisher","first-page":"1993","DOI":"10.1016\/S0140-6736(99)05036-9","volume":"353","author":"B Fisher","year":"1999","unstructured":"Fisher B, Dignam J, Wolmark N, Wickerham DL, Fisher ER, Mamounas E, Smith R, Begovic M, Dimitrov NV, Margolese RG, Kardinal CG, Kavanah MT, Fehrenbacher L, Oishi RH (1999) Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and bowel project B-24 randomised controlled trial. Lancet (London, England) 353(9169):1993\u20132000. \nhttps:\/\/doi.org\/10.1016\/S0140-6736(99)05036-9","journal-title":"Lancet (London, England)"},{"issue":"4","key":"553_CR18","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/S0093-7754(01)90133-2","volume":"28","author":"B Fisher","year":"2001","unstructured":"Fisher B, Land S, Mamounas E, Dignam J, Fisher ER, Wolmark N (2001) Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and bowel project experience. Semin Oncol 28(4):400\u2013418","journal-title":"Semin Oncol"},{"issue":"6","key":"553_CR19","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1093\/jnci\/djr027","volume":"103","author":"IL Wapnir","year":"2011","unstructured":"Wapnir IL, Dignam JJ, Fisher B, Mamounas EP, Anderson SJ, Julian TB, Land SR, Margolese RG, Swain SM, Costantino JP, Wolmark N (2011) Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS. J Natl Cancer Inst 103(6):478\u2013488. \nhttps:\/\/doi.org\/10.1093\/jnci\/djr027","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"553_CR20","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1002\/bjs.4878","volume":"92","author":"NL Barnes","year":"2005","unstructured":"Barnes NL, Boland GP, Davenport A, Knox WF, Bundred NJ (2005) Relationship between hormone receptor status and tumour size, grade and comedo necrosis in ductal carcinoma in situ. Br J Surg 92(4):429\u2013434. \nhttps:\/\/doi.org\/10.1002\/bjs.4878","journal-title":"Br J Surg"},{"issue":"3","key":"553_CR21","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1006\/exmp.2001.2366","volume":"70","author":"EB Claus","year":"2001","unstructured":"Claus EB, Chu P, Howe CL, Davison TL, Stern DF, Carter D, DiGiovanna MP (2001) Pathobiologic findings in DCIS of the breast: morphologic features, angiogenesis, HER-2\/neu and hormone receptors. Exp Mol Pathol 70(3):303\u2013316. \nhttps:\/\/doi.org\/10.1006\/exmp.2001.2366","journal-title":"Exp Mol Pathol"},{"issue":"12","key":"553_CR22","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1200\/JCO.2010.34.0141","volume":"30","author":"DC Allred","year":"2012","unstructured":"Allred DC, Anderson SJ, Paik S, Wickerham DL, Nagtegaal ID, Swain SM, Mamounas EP, Julian TB, Geyer CE Jr, Costantino JP, Land SR, Wolmark N (2012) Adjuvant tamoxifen reduces subsequent breast cancer in women with estrogen receptor-positive ductal carcinoma in situ: a study based on NSABP protocol B-24. J Clin Oncol 30(12):1268\u20131273. \nhttps:\/\/doi.org\/10.1200\/JCO.2010.34.0141","journal-title":"J Clin Oncol"},{"issue":"12","key":"553_CR23","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1016\/s1470-2045(10)70257-6","volume":"11","author":"J Cuzick","year":"2010","unstructured":"Cuzick J, Sestak I, Baum M, Buzdar A, Howell A, Dowsett M, Forbes JF (2010) Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial. Lancet Oncol 11(12):1135\u20131141. \nhttps:\/\/doi.org\/10.1016\/s1470-2045(10)70257-6","journal-title":"Lancet Oncol"},{"key":"553_CR24","doi-asserted-by":"publisher","unstructured":"Menopausal hormone use and ovarian cancer risk: individual participant meta-analysis of 52 epidemiological studies (2015). The Lancet 385 (9980):1835\u20131842. \nhttps:\/\/doi.org\/10.1016\/s0140-6736(14)61687-1","DOI":"10.1016\/s0140-6736(14)61687-1"}],"container-title":["Pathology &amp; Oncology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12253-018-0553-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12253-018-0553-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12253-018-0553-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T06:27:03Z","timestamp":1585722423000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12253-018-0553-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,29]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["553"],"URL":"https:\/\/doi.org\/10.1007\/s12253-018-0553-y","relation":{},"ISSN":["1219-4956","1532-2807"],"issn-type":[{"value":"1219-4956","type":"print"},{"value":"1532-2807","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,29]]},"assertion":[{"value":"1 August 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The author reports no conflicts of interest in this work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}