{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:40:27Z","timestamp":1740148827038,"version":"3.37.3"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T00:00:00Z","timestamp":1531094400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosci. Bull."],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1007\/s12264-018-0254-2","type":"journal-article","created":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T04:06:43Z","timestamp":1531109203000},"page":"849-853","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Acute Restraint Stress Augments 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Neurotoxicity via Increased Toxin Uptake into the Brain in C57BL\/6 Mice"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1471-9062","authenticated-orcid":false,"given":"Yasuhide","family":"Mitsumoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0565-2134","authenticated-orcid":false,"given":"Atsushi","family":"Mori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,7,9]]},"reference":[{"key":"254_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1146\/annurev.neuro.22.1.123","volume":"22","author":"CW Olanow","year":"1999","unstructured":"Olanow CW, Tatton WG. Etiology and pathogenesis of Parkinson\u2019s disease. Annu Rev Neurosci 1999, 22: 123\u2013144.","journal-title":"Annu Rev Neurosci"},{"key":"254_CR2","doi-asserted-by":"publisher","first-page":"S99","DOI":"10.1002\/ana.410440715","volume":"44","author":"Y Mizuno","year":"1998","unstructured":"Mizuno Y, Yoshino H, Ikebe S, Hattori N, Kobayashi T, Shimoda-Matsubayashi S, et al. Mitochondrial dysfunction in Parkinson\u2019s disease. Ann Neurol 1998, 44: S99\u2013S109.","journal-title":"Ann Neurol"},{"key":"254_CR3","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1007\/s12264-017-0178-2","volume":"33","author":"S Li","year":"2017","unstructured":"Li S, Le W. Milestones of Parkinson\u2019s disease research: 200 years of history and beyond. Neurosci Bull 2017, 33: 598\u2013602.","journal-title":"Neurosci Bull"},{"key":"254_CR4","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1136\/jnnp-2013-305911","volume":"85","author":"A Djamshidian","year":"2014","unstructured":"Djamshidian A, Lees AJ. Can stress trigger Parkinson\u2019s disease? J Neurol Neurosurg Psychiatry 2014, 85: 878\u2013881.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"254_CR5","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1002\/ana.410180506","volume":"18","author":"AM Snyder","year":"1985","unstructured":"Snyder AM, Stricker EM, Zigmond MJ. Stress-induced neurological impairments in an animal model of parkinsonism. Ann Neurol 1985, 18: 544\u2013551.","journal-title":"Ann Neurol"},{"key":"254_CR6","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/S0031-9384(02)00939-3","volume":"77","author":"AD Smith","year":"2002","unstructured":"Smith AD, Castro SL, Zigmond MJ. Stress-induced Parkinson\u2019s disease: a working hypothesis. Physiol Behav 2002, 77: 527\u2013531.","journal-title":"Physiol Behav"},{"key":"254_CR7","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1212\/WNL.58.10.1501","volume":"58","author":"AG Schuurman","year":"2002","unstructured":"Schuurman AG, van den Akker M, Ensinck KT, Metsemakers JF, Knottnerus JA, Leentjens AF, et al. Increased risk of Parkinson\u2019s disease after depression: a retrospective cohort study. Neurology 2002, 58: 1501\u20131504.","journal-title":"Neurology"},{"key":"254_CR8","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.physbeh.2017.01.046","volume":"173","author":"U Janakiraman","year":"2017","unstructured":"Janakiraman U, Manivasagam T, Justin Thenmozhi A, Dhanalakshmi C, Essa MM, Song BJ, et al. Chronic mild stress augments MPTP induced neurotoxicity in a murine model of Parkinson\u2019s disease. Physiol Behav 2017, 173:132\u2013143.","journal-title":"Physiol Behav"},{"key":"254_CR9","doi-asserted-by":"publisher","first-page":"e733","DOI":"10.1038\/tp.2016.1","volume":"6","author":"E Lauretti","year":"2016","unstructured":"Lauretti E, Di Meco A, Merali S, Pratic\u00f2 D. Chronic behavioral stress exaggerates motor deficit and neuroinflammation in the MPTP mouse model of Parkinson\u2019s disease. Transl Psychiatry 2016, 6: e733.","journal-title":"Transl Psychiatry"},{"key":"254_CR10","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/1742-2094-11-34","volume":"11","author":"RM Pablos de","year":"2014","unstructured":"de Pablos RM, Herrera AJ, Espinosa-Oliva AM, Sarmiento M, Mu\u00f1oz MF, Machado A, et al. Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation. J Neuroinflammation 2014, 11: 34.","journal-title":"J Neuroinflammation"},{"key":"254_CR11","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.neures.2004.11.008","volume":"51","author":"A Mori","year":"2005","unstructured":"Mori A, Ohashi S, Nakai M, Moriizumi T, Mitsumoto Y. Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL\/6 mice. Neurosci Res 2005, 51: 265\u2013274.","journal-title":"Neurosci Res"},{"key":"254_CR12","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.neures.2004.09.012","volume":"51","author":"Y Mitsumoto","year":"2005","unstructured":"Mitsumoto Y, Mori A, Ohashi S, Nakai M, Moriizumi T. Differential effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the olfactory bulb and the striatum in mice. Neurosci Res 2005, 51: 111\u2013115.","journal-title":"Neurosci Res"},{"key":"254_CR13","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0304-3940(93)90274-O","volume":"161","author":"MS Desole","year":"1993","unstructured":"Desole MS, Esposito G, Fresu L, Migheli R, Enrico P, Miele M et al. Correlation between 1-methyl-4-phenylpyridinium ion (MPP+) levels, ascorbic acid oxidation and glutathione levels in the striatal synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated rat. Neurosci Lett 1993, 161: 121\u2013123.","journal-title":"Neurosci Lett"},{"key":"254_CR14","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1093\/oxfordjournals.jbchem.a131183","volume":"79","author":"O Suzuki","year":"1976","unstructured":"Suzuki O, Noguchi E, Yagi K. A simple fluorometric assay for type B monoamine oxidase activity in rat tissues. J Biochem 1976, 79: 1297\u20131299.","journal-title":"J Biochem"},{"key":"254_CR15","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/S0896-6273(03)00568-3","volume":"39","author":"W Dauer","year":"2003","unstructured":"Dauer W, Przedborski S. Parkinson\u2019s disease: mechanisms and models. Neuron 2003, 39: 889\u2013909.","journal-title":"Neuron"},{"key":"254_CR16","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1152\/physrev.00041.2006","volume":"87","author":"BS McEwen","year":"2007","unstructured":"McEwen BS. Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev 2007, 87: 873\u2013904.","journal-title":"Physiol Rev"},{"key":"254_CR17","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1038\/nrn2639","volume":"10","author":"SJ Lupien","year":"2009","unstructured":"Lupien SJ,  McEwen BS, Gunnar MR, Heim C. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 2009, 10: 434\u2013445.","journal-title":"Nat Rev Neurosci"},{"key":"254_CR18","doi-asserted-by":"publisher","first-page":"26","DOI":"10.3389\/fendo.2013.00026","volume":"4","author":"ND Goncharova","year":"2013","unstructured":"Goncharova ND. Stress responsiveness of the hypothalamic-pituitaryadrenal axis: age-related features of the vasopressinergic regulation. Front Endocrinol 2013, 4: 26.","journal-title":"Front Endocrinol"},{"key":"254_CR19","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1124\/jpet.102.038497","volume":"303","author":"P Esposito","year":"2002","unstructured":"Esposito P, Chandler N, Kandere K, Basu S, Jacobson S, Connolly R, et al. Corticotropin-releasing hormone and brain mast cells regulate blood-brain-barrier permeability induced by acute stress. J Pharmacol Exp Ther 2002, 303: 1061\u20131066.","journal-title":"J Pharmacol Exp Ther"},{"key":"254_CR20","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S0006-8993(00)03026-2","volume":"888","author":"P Esposito","year":"2001","unstructured":"Esposito P, Gheorghe D, Kandere K, Pang X, Connolly R, Jacobson S, et al. Acute stress increases permeability of the blood-brain-barrier through activation of brain mast cells. Brain Res 2001, 888: 117\u2013127.","journal-title":"Brain Res"},{"key":"254_CR21","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/BF01808769","volume":"127","author":"A Sarmento","year":"1994","unstructured":"Sarmento A, Borges N, Lima D. Influence of electrical stimulation of locus coeruleus on the rat blood-brain barrier permeability to sodium fluorescein. Acta Neurochir (Wien) 1994, 127: 215\u2013219.","journal-title":"Acta Neurochir (Wien)"},{"key":"254_CR22","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1038\/jcbfm.1981.19","volume":"1","author":"M Ohata","year":"1981","unstructured":"Ohata M, Fredericks WR, Sundaram U, Rapoport SI. Effects of immobilization stress on regional cerebral blood flow in the conscious rat. J Cereb Blood Flow Metab 1981, 1: 187\u2013194.","journal-title":"J Cereb Blood Flow Metab"},{"key":"254_CR23","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1177\/0271678X16647739","volume":"36","author":"M Roszkowski","year":"2016","unstructured":"Roszkowski M, Bohacek J. Stress does not increase blood-brain barrier permeability in mice. J Cereb Blood Flow Metab 2016, 36: 1304\u20131315.","journal-title":"J Cereb Blood Flow Metab"},{"key":"254_CR24","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1097\/00002826-198808000-00004","volume":"11","author":"K Urakami","year":"1988","unstructured":"Urakami K, Masaki N, Shimoda K, Nishikawa S, Takahashi K. Increase of striatal dopamine turnover by stress in MPTP-treated mice. Clin Neuropharmacol 1988, 11: 360\u2013368.","journal-title":"Clin Neuropharmacol"},{"key":"254_CR25","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1007\/s12264-016-0089-7","volume":"33","author":"S Li","year":"2017","unstructured":"Li S, Wang Y, Wang F, Hu LF, Liu CF. A new perspective for Parkinson\u2019s disease: circadian rhythm. Neurosci Bull 2017, 33: 62\u201372.","journal-title":"Neurosci Bull"},{"key":"254_CR26","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.neures.2008.09.009","volume":"63","author":"A Muroyama","year":"2009","unstructured":"Muroyama A, Inaka M, Matsushima H, Sugino H, Marunaka Y, Mitsumoto Y. Enhanced susceptibility to MPTP neurotoxicity in magnesium-deficient C57BL\/6\u00a0N mice. Neurosci Res 2009, 63: 72\u201375.","journal-title":"Neurosci Res"}],"container-title":["Neuroscience Bulletin"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12264-018-0254-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12264-018-0254-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12264-018-0254-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T19:26:44Z","timestamp":1562614004000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12264-018-0254-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,9]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["254"],"URL":"https:\/\/doi.org\/10.1007\/s12264-018-0254-2","relation":{},"ISSN":["1673-7067","1995-8218"],"issn-type":[{"type":"print","value":"1673-7067"},{"type":"electronic","value":"1995-8218"}],"subject":[],"published":{"date-parts":[[2018,7,9]]},"assertion":[{"value":"30 October 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 July 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}