{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:41:13Z","timestamp":1781570473768,"version":"3.54.5"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosci. Bull."],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1007\/s12264-023-01133-7","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T04:01:39Z","timestamp":1696910499000},"page":"1891-1894","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Propofol Brings on the Light for Depression Therapy"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9993-4959","authenticated-orcid":false,"given":"Yun","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8925-1372","authenticated-orcid":false,"given":"Hongli","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4640-2609","authenticated-orcid":false,"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,10]]},"reference":[{"key":"1133_CR1","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S0140-6736(22)02080-3","volume":"401","author":"S Marwaha","year":"2023","unstructured":"Marwaha S, Palmer E, Suppes T, Cons E, Young AH, Upthegrove R. Novel and emerging treatments for major depression. Lancet 2023, 401: 141\u2013153.","journal-title":"Lancet"},{"key":"1133_CR2","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1007\/s12264-021-00638-3","volume":"37","author":"Z Li","year":"2021","unstructured":"Li Z, Ruan M, Chen J, Fang Y. Major depressive disorder: Advances in neuroscience research and translational applications. Neurosci Bull 2021, 37: 863\u2013880.","journal-title":"Neurosci Bull"},{"key":"1133_CR3","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1177\/2050640617736231","volume":"6","author":"T Brechmann","year":"2018","unstructured":"Brechmann T, Maier C, Kaisler M, Vollert J, Schmiegel W, Pak S. Propofol sedation during gastrointestinal endoscopy arouses euphoria in a large subset of patients. United European Gastroenterol J 2018, 6: 536\u2013546.","journal-title":"United European Gastroenterol J"},{"key":"1133_CR4","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.brainresbull.2023.03.004","volume":"196","author":"Y Jiang","year":"2023","unstructured":"Jiang Y, Zou M, Wang Y, Wang Y. Nucleus accumbens in the pathogenesis of major depressive disorder: A brief review. Brain Res Bull 2023, 196: 68\u201375.","journal-title":"Brain Res Bull"},{"key":"1133_CR5","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1016\/j.neuron.2023.02.017","volume":"111","author":"XN Zhu","year":"2023","unstructured":"Zhu XN, Li J, Qiu GL, Wang L, Lu C, Guo YG, et al. Propofol exerts anti-anhedonia effects via inhibiting the dopamine transporter. Neuron 2023, 111: 1626-1636.e6.","journal-title":"Neuron"},{"key":"1133_CR6","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1213\/ANE.0000000000005847","volume":"135","author":"I Nagata","year":"2022","unstructured":"Nagata I, Sasaki M, Miyazaki T, Saeki K, Ogawa KI, Kamiya Y. Subanesthetic dose of propofol activates the reward system in rats. Anesth Analg 2022, 135: 414\u2013426.","journal-title":"Anesth Analg"},{"key":"1133_CR7","first-page":"1847","volume":"10","author":"J Luo","year":"2014","unstructured":"Luo J, Min S, Wei K, Cao J, Wang B, Li P, et al. Propofol prevents electroconvulsive-shock-induced memory impairment through regulation of hippocampal synaptic plasticity in a rat model of depression. Neuropsychiatr Dis Treat 2014, 10: 1847\u20131859.","journal-title":"Neuropsychiatr Dis Treat"},{"key":"1133_CR8","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/j.neuron.2019.03.003","volume":"102","author":"DC Castro","year":"2019","unstructured":"Castro DC, Bruchas MR. A motivational and neuropeptidergic hub: Anatomical and functional diversity within the nucleus accumbens shell. Neuron 2019, 102: 529\u2013552.","journal-title":"Neuron"},{"key":"1133_CR9","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.neuroscience.2014.06.006","volume":"282","author":"JJ Walsh","year":"2014","unstructured":"Walsh JJ, Han MH. The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context. Neuroscience 2014, 282: 101\u2013108.","journal-title":"Neuroscience"},{"key":"1133_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.wneu.2019.01.254","volume":"126","author":"YS Park","year":"2019","unstructured":"Park YS, Sammartino F, Young NA, Corrigan J, Krishna V, Rezai AR. Anatomic review of the ventral capsule\/ventral Striatum and the nucleus accumbens to guide target selection for deep brain stimulation for obsessive-compulsive disorder. World Neurosurg 2019, 126: 1\u201310.","journal-title":"World Neurosurg"},{"key":"1133_CR11","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1177\/2045125318791944","volume":"8","author":"Y Lee","year":"2018","unstructured":"Lee Y, Subramaniapillai M, Brietzke E, Mansur RB, Ho RC, Yim SJ, et al. Anti-cytokine agents for anhedonia: Targeting inflammation and the immune system to treat dimensional disturbances in depression. Ther Adv Psychopharmacol 2018, 8: 337\u2013348.","journal-title":"Ther Adv Psychopharmacol"},{"key":"1133_CR12","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1017\/S1092852918001207","volume":"24","author":"Z Pan","year":"2019","unstructured":"Pan Z, Park C, Brietzke E, Zuckerman H, Rong C, Mansur RB, et al. Cognitive impairment in major depressive disorder. CNS Spectr 2019, 24: 22\u201329.","journal-title":"CNS Spectr"},{"key":"1133_CR13","doi-asserted-by":"publisher","first-page":"875","DOI":"10.3724\/abbs.2022067","volume":"54","author":"P Liu","year":"2022","unstructured":"Liu P, Zhao S, Qiao H, Li T, Mi W, Xu Z, et al. Does propofol definitely improve postoperative cognitive dysfunction? A review of propofol-related cognitive impairment. Acta Biochim Biophys Sin 2022, 54: 875\u2013881.","journal-title":"Acta Biochim Biophys Sin"}],"container-title":["Neuroscience Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12264-023-01133-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12264-023-01133-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12264-023-01133-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T14:27:18Z","timestamp":1700490438000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12264-023-01133-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,10]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["1133"],"URL":"https:\/\/doi.org\/10.1007\/s12264-023-01133-7","relation":{},"ISSN":["1673-7067","1995-8218"],"issn-type":[{"value":"1673-7067","type":"print"},{"value":"1995-8218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,10]]},"assertion":[{"value":"11 April 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that there are no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}