{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T06:00:21Z","timestamp":1784959221565,"version":"3.55.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:00:00Z","timestamp":1784937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:00:00Z","timestamp":1784937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosci. Bull."],"DOI":"10.1007\/s12264-026-01689-0","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:00:41Z","timestamp":1784955641000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cocaine Hijacks the Npas4-dependent Somatostatin Ensembles in the mPFC to Mediate Attention"],"prefix":"10.1007","author":[{"given":"Xutian","family":"Hou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunxiu","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2351-6873","authenticated-orcid":false,"given":"Feifei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changyou","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0038-3523","authenticated-orcid":false,"given":"Tao","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,25]]},"reference":[{"key":"1689_CR1","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.neulet.2006.11.041","volume":"413","author":"Z Wang","year":"2007","unstructured":"Wang Z, Ordway GA, Woolverton W. Effects of cocaine on monoamine uptake as measured ex vivo. Neurosci Lett 2007, 413: 191\u2013195.","journal-title":"Neurosci Lett"},{"key":"1689_CR2","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1038\/nrn3381","volume":"14","author":"SJ Russo","year":"2013","unstructured":"Russo SJ, Nestler EJ. The brain reward circuitry in mood disorders. Nat Rev Neurosci 2013, 14: 609\u2013625.","journal-title":"Nat Rev Neurosci"},{"key":"1689_CR3","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.neuron.2011.01.017","volume":"69","author":"C L\u00fcscher","year":"2011","unstructured":"L\u00fcscher C, Malenka RC. Drug-evoked synaptic plasticity in addiction: From molecular changes to circuit remodeling. Neuron 2011, 69: 650\u2013663.","journal-title":"Neuron"},{"key":"1689_CR4","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1016\/j.neuropharm.2011.01.036","volume":"61","author":"M Mameli","year":"2011","unstructured":"Mameli M, L\u00fcscher C. Synaptic plasticity and addiction: Learning mechanisms gone awry. Neuropharmacology 2011, 61: 1052\u20131059.","journal-title":"Neuropharmacology"},{"key":"1689_CR5","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/S0959-4388(00)00204-X","volume":"11","author":"RD Rogers","year":"2001","unstructured":"Rogers RD, Robbins TW. Investigating the neurocognitive deficits associated with chronic drug misuse. Curr Opin Neurobiol 2001, 11: 250\u2013257.","journal-title":"Curr Opin Neurobiol"},{"key":"1689_CR6","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/S0376-8716(02)00110-2","volume":"68","author":"G Fein","year":"2002","unstructured":"Fein G, Di Sclafani V, Meyerhoff DJ. Prefrontal cortical volume reduction associated with frontal cortex function deficit in 6-week abstinent crack-cocaine dependent men. Drug Alcohol Depend 2002, 68: 87\u201393.","journal-title":"Drug Alcohol Depend"},{"key":"1689_CR7","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s00213-004-1845-3","volume":"175","author":"TA Paine","year":"2004","unstructured":"Paine TA, Olmstead MC. Cocaine disrupts both behavioural inhibition and conditional discrimination in rats. Psychopharmacology 2004, 175: 443\u2013450.","journal-title":"Psychopharmacology"},{"key":"1689_CR8","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1038\/s41386-019-0578-2","volume":"45","author":"D V\u00e1zquez","year":"2020","unstructured":"V\u00e1zquez D, Pribut HJ, Burton AC, Tennyson SS, Roesch MR. Prior cocaine self-administration impairs attention signals in anterior cingulate cortex. Neuropsychopharmacology 2020, 45: 833\u2013841.","journal-title":"Neuropsychopharmacology"},{"key":"1689_CR9","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.7150\/thno.90792","volume":"14","author":"F Wang","year":"2024","unstructured":"Wang F, Liu CB, Wang Y, Wang XX, Yang YY, Jiang CY. Morphine- and foot shock-responsive neuronal ensembles in the VTA possess different connectivity and biased GPCR signaling pathway. Theranostics 2024, 14: 1126\u20131146.","journal-title":"Theranostics"},{"key":"1689_CR10","doi-asserted-by":"publisher","first-page":"1986","DOI":"10.1038\/s41593-019-0524-y","volume":"22","author":"Y Zhou","year":"2019","unstructured":"Zhou Y, Zhu H, Liu Z, Chen X, Su X, Ma C, et al. A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine. Nat Neurosci 2019, 22: 1986\u20131999.","journal-title":"Nat Neurosci"},{"key":"1689_CR11","doi-asserted-by":"publisher","first-page":"6170","DOI":"10.1038\/s41380-021-01321-9","volume":"26","author":"C Jiang","year":"2021","unstructured":"Jiang C, Yang X, He G, Wang F, Wang Z, Xu W, et al. CRHCeA\u2192VTA inputs inhibit the positive ensembles to induce negative effect of opiate withdrawal. Mol Psychiatry 2021, 26: 6170\u20136186.","journal-title":"Mol Psychiatry"},{"key":"1689_CR12","doi-asserted-by":"publisher","first-page":"5971","DOI":"10.1038\/s41467-024-50099-1","volume":"15","author":"BW Hughes","year":"2024","unstructured":"Hughes BW, Huebschman JL, Tsvetkov E, Siemsen BM, Snyder KK, Akiki RM, et al. NPAS4 supports cocaine-conditioned cues in rodents by controlling the cell type-specific activation balance in the nucleus accumbens. Nat Commun 2024, 15: 5971.","journal-title":"Nat Commun"},{"key":"1689_CR13","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1038\/nrn3597","volume":"14","author":"FC Cruz","year":"2013","unstructured":"Cruz FC, Koya E, Guez-Barber DH, Bossert JM, Lupica CR, Shaham Y, et al. New technologies for examining the role of neuronal ensembles in drug addiction and fear. Nat Rev Neurosci 2013, 14: 743\u2013754.","journal-title":"Nat Rev Neurosci"},{"key":"1689_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2023.102813","volume":"83","author":"X Liu","year":"2023","unstructured":"Liu X, Wang F, Le Q, Ma L. Cellular and molecular basis of drug addiction: The role of neuronal ensembles in addiction. Curr Opin Neurobiol 2023, 83: 102813.","journal-title":"Curr Opin Neurobiol"},{"key":"1689_CR15","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1038\/nature07319","volume":"455","author":"Y Lin","year":"2008","unstructured":"Lin Y, Bloodgood BL, Hauser JL, Lapan AD, Koon AC, Kim TK, et al. Activity-dependent regulation of inhibitory synapse development by Npas4. Nature 2008, 455: 1198\u20131204.","journal-title":"Nature"},{"key":"1689_CR16","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1016\/j.cell.2014.03.058","volume":"157","author":"I Spiegel","year":"2014","unstructured":"Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, et al. Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell 2014, 157: 1216\u20131229.","journal-title":"Cell"},{"key":"1689_CR17","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.tins.2016.02.003","volume":"39","author":"X Sun","year":"2016","unstructured":"Sun X, Lin Y. Npas4: Linking neuronal activity to memory. Trends Neurosci 2016, 39: 264\u2013275.","journal-title":"Trends Neurosci"},{"key":"1689_CR18","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1126\/science.1208049","volume":"334","author":"K Ramamoorthi","year":"2011","unstructured":"Ramamoorthi K, Fropf R, Belfort GM, Fitzmaurice HL, McKinney RM, Neve RL, et al. Npas4 regulates a transcriptional program in CA3 required for contextual memory formation. Science 2011, 334: 1669\u20131675.","journal-title":"Science"},{"key":"1689_CR19","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/j.cell.2020.02.055","volume":"181","author":"X Sun","year":"2020","unstructured":"Sun X, Bernstein MJ, Meng M, Rao S, S\u00f8rensen AT, Yao L, et al. Functionally distinct neuronal ensembles within the memory engram. Cell 2020, 181: 410-423.e17.","journal-title":"Cell"},{"key":"1689_CR20","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1016\/j.neuron.2018.01.026","volume":"97","author":"FJ Weng","year":"2018","unstructured":"Weng FJ, Garcia RI, Lutzu S, Alvi\u00f1a K, Zhang Y, Dushko M, et al. Npas4 is a critical regulator of learning-induced plasticity at mossy fiber-CA3 synapses during contextual memory formation. Neuron 2018, 97: 1137-1152.e5.","journal-title":"Neuron"},{"key":"1689_CR21","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1038\/s41422-025-01157-w","volume":"35","author":"T Jin","year":"2025","unstructured":"Jin T, Yang Y, Guo Y, Zhang Y, Le Q, Huang N, et al. Disturbed engram network caused by NPTX downregulation underlies aging-related contextual fear memory deficits. Cell Res 2025, 35: 656\u2013674.","journal-title":"Cell Res"},{"key":"1689_CR22","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1126\/science.adp1562","volume":"386","author":"RM Akiki","year":"2024","unstructured":"Akiki RM, Cornbrooks RG, Magami K, Greige A, Snyder KK, Wood DJ, et al. A long noncoding ERNA forms R-loops to shape emotional experience\u2013induced behavioral adaptation. Science 2024, 386: 1282\u20131289.","journal-title":"Science"},{"key":"1689_CR23","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.neuron.2017.09.015","volume":"96","author":"M Taniguchi","year":"2017","unstructured":"Taniguchi M, Carreira MB, Cooper YA, Bobadilla AC, Heinsbroek JA, Koike N, et al. HDAC5 and its target gene, Npas4, function in the nucleus accumbens to regulate cocaine-conditioned behaviors. Neuron 2017, 96: 130\u2013144.e6.","journal-title":"Neuron"},{"key":"1689_CR24","doi-asserted-by":"publisher","first-page":"11741","DOI":"10.1096\/fj.202000398R","volume":"34","author":"T Jin","year":"2020","unstructured":"Jin T, Chen R, Shao M, Yang X, Ma L, Wang F. Dorsal hippocampus- and ACC-projecting medial septum neurons differentially contribute to the recollection of episodic-like memory. FASEB J 2020, 34: 11741\u201311753.","journal-title":"FASEB J"},{"key":"1689_CR25","doi-asserted-by":"crossref","unstructured":"Ting JT, Daigle TL, Chen Q, Feng G. Acute brain slice methods for adult and aging animals: Application of targeted patch clamp analysis and optogenetics. Patch-Clamp Methods and Protocols. New York, NY: Springer New York, 2014: 221\u2013242.","DOI":"10.1007\/978-1-4939-1096-0_14"},{"key":"1689_CR26","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.biopsych.2017.11.008","volume":"83","author":"S Parnaudeau","year":"2018","unstructured":"Parnaudeau S, Bolkan SS, Kellendonk C. The mediodorsal thalamus: An essential partner of the prefrontal cortex for cognition. Biol Psychiatry 2018, 83: 648\u2013656.","journal-title":"Biol Psychiatry"},{"key":"1689_CR27","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.neuron.2019.06.005","volume":"103","author":"MM Halassa","year":"2019","unstructured":"Halassa MM, Sherman SM. Thalamocortical circuit motifs: A general framework. Neuron 2019, 103: 762\u2013770.","journal-title":"Neuron"},{"key":"1689_CR28","doi-asserted-by":"publisher","first-page":"104","DOI":"10.3389\/fnsys.2016.00104","volume":"10","author":"SK Peters","year":"2016","unstructured":"Peters SK, Dunlop K, Downar J. Cortico-striatal-thalamic loop circuits of the salience network: A central pathway in psychiatric disease and treatment. Front Syst Neurosci 2016, 10: 104.","journal-title":"Front Syst Neurosci"},{"key":"1689_CR29","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1038\/nature15398","volume":"526","author":"RD Wimmer","year":"2015","unstructured":"Wimmer RD, Schmitt LI, Davidson TJ, Nakajima M, Deisseroth K, Halassa MM. Thalamic control of sensory selection in divided attention. Nature 2015, 526: 705\u2013709.","journal-title":"Nature"},{"key":"1689_CR30","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1176\/jnp.10.3.280","volume":"10","author":"KI Bolla","year":"1998","unstructured":"Bolla KI, Cadet JL, London ED. The neuropsychiatry of chronic cocaine abuse. J Neuropsychiatry Clin Neurosci 1998, 10: 280\u2013289.","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"1689_CR31","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1186\/s40478-024-01890-0","volume":"12","author":"X Qu","year":"2024","unstructured":"Qu X, Yang P, Zhai R, Xiong ZQ. Inhibition of RtTg neurons reverses methamphetamine-induced attention deficits. Acta Neuropathol Commun 2024, 12: 179.","journal-title":"Acta Neuropathol Commun"},{"key":"1689_CR32","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1016\/j.biopsych.2006.07.031","volume":"61","author":"R Salo","year":"2007","unstructured":"Salo R, Nordahl TE, Natsuaki Y, Leamon MH, Galloway GP, Waters C, et al. Attentional control and brain metabolite levels in methamphetamine abusers. Biol Psychiatry 2007, 61: 1272\u20131280.","journal-title":"Biol Psychiatry"},{"key":"1689_CR33","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1002\/hup.616","volume":"19","author":"JW Hopper","year":"2004","unstructured":"Hopper JW, Karlsgodt KH, Adler CM, Macklin EA, Lukas SE, Elman I. Effects of acute Cortisol and cocaine administration on attention, recall and recognition task performance in individuals with cocaine dependence. Hum Psychopharmacol Clin Exp 2004, 19: 511\u2013516.","journal-title":"Hum Psychopharmacol Clin Exp"},{"key":"1689_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.109417","volume":"36","author":"S Kim","year":"2021","unstructured":"Kim S, Park D, Kim J, Kim D, Kim H, Mori T, et al. Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior. Cell Rep 2021, 36: 109417.","journal-title":"Cell Rep"},{"key":"1689_CR35","doi-asserted-by":"publisher","first-page":"3339","DOI":"10.1016\/j.neuron.2022.08.018","volume":"110","author":"J Yang","year":"2022","unstructured":"Yang J, Serrano P, Yin X, Sun X, Lin Y, Chen SX. Functionally distinct NPAS4-expressing somatostatin interneuron ensembles critical for motor skill learning. Neuron 2022, 110: 3339\u20133355.e8.","journal-title":"Neuron"},{"key":"1689_CR36","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1038\/s41586-021-04056-3","volume":"600","author":"A Mukherjee","year":"2021","unstructured":"Mukherjee A, Lam NH, Wimmer RD, Halassa MM. Thalamic circuits for independent control of prefrontal signal and noise. Nature 2021, 600: 100\u2013104.","journal-title":"Nature"},{"key":"1689_CR37","doi-asserted-by":"publisher","first-page":"2407387","DOI":"10.1002\/advs.202407387","volume":"12","author":"L Tian","year":"2025","unstructured":"Tian L, Li XH, Zhao YL, Yi HY, Liu XR, Yao R, et al. DNMT3a downregulation ttriggered upregulation of GABAA receptor in the mPFC promotes paclitaxel-induced pain and anxiety in male mice. Adv Sci 2025, 12: 2407387.","journal-title":"Adv Sci"},{"key":"1689_CR38","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s12264-024-01280-5","volume":"41","author":"J Feng","year":"2025","unstructured":"Feng J, Wang X, Pan M, Li CX, Zhang Z, Sun M, et al. The medial prefrontal cortex-basolateral amygdala circuit mediates anxiety in Shank3 InsG3680 knock-in mice. Neurosci Bull 2025, 41: 77\u201392.","journal-title":"Neurosci Bull"},{"key":"1689_CR39","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1038\/s41380-024-02634-1","volume":"30","author":"YX Li","year":"2025","unstructured":"Li YX, Tan ZN, Li XH, Ma B, Adu Nti F, Lv XQ, et al. Correction: Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice. Mol Psychiatry 2025, 30: 364.","journal-title":"Mol Psychiatry"},{"key":"1689_CR40","doi-asserted-by":"publisher","first-page":"e75631","DOI":"10.7554\/eLife.75631","volume":"12","author":"BW Hughes","year":"2023","unstructured":"Hughes BW, Siemsen BM, Tsvetkov E, Berto S, Kumar J, et al. NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress-induced anhedonia-like behavior and reductions in excitatory synapses. eLife 2023, 12: e75631.","journal-title":"eLife"},{"key":"1689_CR41","doi-asserted-by":"publisher","first-page":"3795","DOI":"10.1038\/s41380-022-01610-x","volume":"27","author":"LY Ren","year":"2022","unstructured":"Ren LY, Cicvaric A, Zhang H, Meyer MA, Guedea AL, Gao P, et al. Stress-induced changes of the cholinergic circuitry promote retrieval-based generalization of aversive memories. Mol Psychiatry 2022, 27: 3795\u20133805.","journal-title":"Mol Psychiatry"},{"key":"1689_CR42","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.brainres.2014.11.005","volume":"1628","author":"FC Cruz","year":"2015","unstructured":"Cruz FC, Javier Rubio F, Hope BT. Using c-fos to study neuronal ensembles in corticostriatal circuitry of addiction. Brain Res 2015, 1628: 157\u2013173.","journal-title":"Brain Res"},{"key":"1689_CR43","doi-asserted-by":"publisher","first-page":"61","DOI":"10.12717\/DR.2015.19.2.061","volume":"19","author":"L Chung","year":"2015","unstructured":"Chung L. A brief introduction to the transduction of neural activity into fos signal. Dev Reprod 2015, 19: 61\u201367.","journal-title":"Dev Reprod"},{"key":"1689_CR44","doi-asserted-by":"publisher","first-page":"EMBR202051882","DOI":"10.15252\/embr.202051882","volume":"22","author":"T Lissek","year":"2021","unstructured":"Lissek T, Andrianarivelo A, Saint-Jour E, Allichon MC, Bauersachs HG, Nassar M, et al. Npas4 regulates medium spiny neuron physiology and gates cocaine-induced hyperlocomotion. EMBO Rep 2021, 22: EMBR202051882.","journal-title":"EMBO Rep"},{"key":"1689_CR45","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12947","volume":"26","author":"ET Jorgensen","year":"2021","unstructured":"Jorgensen ET, Gonzalez AE, Harkness JH, Hegarty DM, Thakar A, Burchi DJ, et al. Cocaine memory reactivation induces functional adaptations within parvalbumin interneurons in the rat medial prefrontal cortex. Addict Biol 2021, 26: e12947.","journal-title":"Addict Biol"},{"key":"1689_CR46","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1093\/ilar.53.1.14","volume":"53","author":"V Quinones-Jenab","year":"2012","unstructured":"Quinones-Jenab V, Jenab S. Influence of sex differences and gonadal hormones on cocaine addiction. ILAR J 2012, 53: 14\u201322.","journal-title":"ILAR J"},{"key":"1689_CR47","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.nbd.2016.12.012","volume":"99","author":"R Shepard","year":"2017","unstructured":"Shepard R, Heslin K, Coutellier L. The transcription factor Npas4 contributes to adolescent development of prefrontal inhibitory circuits, and to cognitive and emotional functions: Implications for neuropsychiatric disorders. Neurobiol Dis 2017, 99: 36\u201346.","journal-title":"Neurobiol Dis"},{"key":"1689_CR48","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1124\/pr.115.011163","volume":"68","author":"JB Becker","year":"2016","unstructured":"Becker JB, Koob GF. Sex differences in animal models: Focus on addiction. Pharmacol Rev 2016, 68: 242\u2013263.","journal-title":"Pharmacol Rev"}],"container-title":["Neuroscience Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12264-026-01689-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12264-026-01689-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12264-026-01689-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:00:42Z","timestamp":1784955642000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12264-026-01689-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,25]]},"references-count":48,"alternative-id":["1689"],"URL":"https:\/\/doi.org\/10.1007\/s12264-026-01689-0","relation":{},"ISSN":["1673-7067","1995-8218"],"issn-type":[{"value":"1673-7067","type":"print"},{"value":"1995-8218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,25]]},"assertion":[{"value":"11 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Ethics"}}]}}