{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:35:34Z","timestamp":1790516134083,"version":"4.1.0"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. of Cardiovasc. Trans. Res."],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1007\/s12265-011-9325-8","type":"journal-article","created":{"date-parts":[[2011,11,2]],"date-time":"2011-11-02T15:49:37Z","timestamp":1320248977000},"page":"92-99","source":"Crossref","is-referenced-by-count":32,"title":["Plasma Omega-3 Polyunsaturated Fatty Acids and Survival in Patients with Chronic Heart Failure and Major Depressive Disorder"],"prefix":"10.1007","volume":"5","author":[{"name":"for the SADHART-CHF Investigators","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Oken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Fiuzat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda K.","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Martsberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maragatha","family":"Kuchibhatla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rima","family":"Kaddurah-Daouk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Steffens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Baillie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Cuffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranga","family":"Krishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"O\u2019Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,11,1]]},"reference":[{"issue":"1","key":"9325_CR1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1001\/jama.279.1.23","volume":"279","author":"CM Albert","year":"1998","unstructured":"Albert, C. M., Hennekens, C. H., O'Donnell, C. J., et al. (1998). Fish consumption and risk of sudden cardiac death. Journal of the American Medical Association, 279(1), 23\u201328.","journal-title":"Journal of the American Medical Association"},{"issue":"19","key":"9325_CR2","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1056\/NEJM198505093121901","volume":"312","author":"D Kromhout","year":"1985","unstructured":"Kromhout, D., Bosschieter, E. B., & Coulander, C. D. (1985). The inverse relation between fish consumption and 20-year mortality from coronary heart disease. New England Journal of Medicine, 312(19), 1205\u20131209.","journal-title":"New England Journal of Medicine"},{"key":"9325_CR3","first-page":"1608","volume-title":"Cardiovascular drug therapy","author":"CJ Lavie","year":"1996","unstructured":"Lavie, C. J., & Milani, R. V. (1996). Fish oils. In F. H. Messerli (Ed.), Cardiovascular drug therapy (pp. 1608\u20131613). Philadelphia: Saunders."},{"issue":"3","key":"9325_CR4","doi-asserted-by":"crossref","first-page":"324","DOI":"10.4065\/83.3.324","volume":"83","author":"JH Lee","year":"2008","unstructured":"Lee, J. H., O'Keefe, J. H., Lavie, C. J., Marchioli, R., & Harris, W. S. (2008). Omega-3 fatty acids for cardioprotection. Mayo Clinic Proceedings, 83(3), 324\u2013332.","journal-title":"Mayo Clinic Proceedings"},{"issue":"9567","key":"9325_CR5","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S0140-6736(07)60527-3","volume":"369","author":"M Yokoyama","year":"2007","unstructured":"Yokoyama, M., Origasa, H., Matsuzaki, M., et al. (2007). Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): A randomised openlabel, blinded endpoint analysis. Lancet, 369(9567), 1090\u20131098.","journal-title":"Lancet"},{"issue":"9177","key":"9325_CR6","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0140-6736(99)07072-5","volume":"354","author":"F Valagussa","year":"1999","unstructured":"Valagussa, F., Franzosi, M. G., Geraci, E., et al. (1999). Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial. Lancet, 354(9177), 447\u2013455.","journal-title":"Lancet"},{"issue":"6","key":"9325_CR7","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1161\/CIRCULATIONAHA.108.191627","volume":"119","author":"WS Harris","year":"2009","unstructured":"Harris, W. S., Mozaffarian, D., Rimm, E., et al. (2009). Omega-6 fatty acids and risk for cardiovascular disease a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation, 119(6), 902\u2013907. doi: 10.1161\/circulationaha.108.191627 .","journal-title":"Circulation"},{"issue":"2","key":"9325_CR8","doi-asserted-by":"crossref","first-page":"E20","DOI":"10.1161\/01.ATV.0000038493.65177.94","volume":"23","author":"PM Kris-Etherton","year":"2003","unstructured":"Kris-Etherton, P. M., Harris, W. S., Appel, L. J., & Nutr, C. (2003). Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Arteriosclerosis Thrombosis and Vascular Biology, 23(2), E20\u2013E31. doi: 10.1161\/01.atv.0000038493.65177.94 .","journal-title":"Arteriosclerosis Thrombosis and Vascular Biology"},{"issue":"1","key":"9325_CR9","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1161\/CIRCULATIONAHA.106.176158","volume":"114","author":"AH Lichtenstein","year":"2006","unstructured":"Lichtenstein, A. H., Appel, L. J., Brands, M., et al. (2006). Diet and lifestyle recommendations revision 2006\u2014A scientific statement from the American Heart Association Nutrition Committee. Circulation, 114(1), 82. doi: 10.1161\/circulationaha.106.176158 .","journal-title":"Circulation"},{"issue":"9645","key":"9325_CR10","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0140-6736(08)61239-8","volume":"372","author":"L Tavazzi","year":"2008","unstructured":"Tavazzi, L., Maggioni, A. P., Marchioli, R., et al. (2008). Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): A randomised, double-blind, placebo-controlled trial. Lancet, 372(9645), 1223\u20131230. doi: 10.1016\/s0140-6736(08)61239-8 .","journal-title":"Lancet"},{"issue":"3","key":"9325_CR11","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.ahj.2008.05.003","volume":"156","author":"W Jiang","year":"2008","unstructured":"Jiang, W., O'Connor, C., Silva, S. G., et al. (2008). Safety and efficacy of sertraline for depression in patients with CHF (SADHART-CHF): A randomized, double-blind, placebo-controlled trial of sertraline for major depression with congestive heart failure. American Heart Journal, 156(3), 437\u2013444. doi: 10.1016\/j.ahj.2008.05.003 .","journal-title":"American Heart Journal"},{"issue":"9","key":"9325_CR12","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.jacc.2010.03.068","volume":"56","author":"CM O'Connor","year":"2010","unstructured":"O'Connor, C. M., Jiang, W., Kuchibhatla, M., et al. (2010). Safety and efficacy of sertraline for depression in patients with heart failure: Results of the SADHART-CHF trial. Journal of the American College of Cardiology, 56(9), 692\u2013699.","journal-title":"Journal of the American College of Cardiology"},{"issue":"3","key":"9325_CR13","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1207\/s15327752jpa6703_13","volume":"67","author":"AT Beck","year":"1996","unstructured":"Beck, A. T., Steer, R. A., Ball, R., & Ranieri, W. F. (1996). Comparison of Beck Depression Inventories-IA and -II in psychiatric outpatients. Journal of Personality Assessment, 67(3), 588\u2013597.","journal-title":"Journal of Personality Assessment"},{"issue":"2","key":"9325_CR14","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s11745-007-3140-7","volume":"43","author":"E Bailey-Hall","year":"2008","unstructured":"Bailey-Hall, E., Nelson, E. B., & Ryan, A. S. (2008). Validation of a rapid measure of blood PUFA levels in humans. Lipids, 43(2), 181\u2013186. doi: 10.1007\/s11745-007-3140-7 .","journal-title":"Lipids"},{"key":"9325_CR15","first-page":"113","volume":"1","author":"WEM Lands","year":"2003","unstructured":"Lands, W. E. M. (2003). Functional foods in primary prevention or nutraceuticals in secondary prevention? Current Topics in Nutraceutical Research, 1, 113\u2013119.","journal-title":"Current Topics in Nutraceutical Research"},{"issue":"1","key":"9325_CR16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0167-5273(00)00442-3","volume":"78","author":"F Paganelli","year":"2001","unstructured":"Paganelli, F., Maixent, J. M., Duran, M. J., Parhizgar, R., Pieroni, G., & Sennoune, S. (2001). Altered erythrocyte n-3 fatty acids in Mediterranean patients with coronary artery disease. Int J Cardiol, 78(1), 27\u201332.","journal-title":"Int J Cardiol"},{"issue":"22","key":"9325_CR17","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1161\/01.CIR.102.22.2677","volume":"102","author":"T Rissanen","year":"2000","unstructured":"Rissanen, T., Voutilainen, S., Nyyssonen, K., Lakka, T. A., & Salonen, J. T. (2000). Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events\u2014the Kuopio Ischaemic Heart Disease Risk Factor Study. Circulation, 102(22), 2677\u20132679.","journal-title":"Circulation"},{"issue":"7","key":"9325_CR18","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00059-004-2602-4","volume":"29","author":"H Rupp","year":"2004","unstructured":"Rupp, H., Wagner, D., Rupp, T., Schulte, L. M., & Maisch, B. (2004). Risk stratification by the \u201cEPA\u2009+\u2009DHA level\u201d and the \u201cEPA\/AA ratio\u201d\u2014Focus on anti-inflammatory and antiarrhythmogenic effects of long-chain omega-3 fatty acids. Herz, 29(7), 673\u2013685. doi: 10.1007\/s00059-004-2602-4 .","journal-title":"Herz"},{"issue":"17","key":"9325_CR19","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/jama.1995.03530170043030","volume":"274","author":"DS Siscovick","year":"1995","unstructured":"Siscovick, D. S., Raghunathan, T. E., King, I., et al. (1995). Dietary-intake and cell-membrane levels of long-chain n-3 polyunsaturated fatty-acids and the risk of primary cardiac-arrest. JAMA: The Journal of the American Medical Association, 274(17), 1363\u20131367.","journal-title":"JAMA : The Journal of the American Medical Association"},{"issue":"1","key":"9325_CR20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.atherosclerosis.2007.03.018","volume":"193","author":"WS Harris","year":"2007","unstructured":"Harris, W. S., Poston, W. C., & Haddock, C. K. (2007). Tissue n-3 and n-6 fatty acids and risk for coronary heart disease events. Atherosclerosis, 193(1), 1\u201310. doi: 10.1016\/j.atherosclerosis.2007.03.018 .","journal-title":"Atherosclerosis"},{"issue":"2","key":"9325_CR21","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/01.mco.0000214566.67439.58","volume":"9","author":"TA Mori","year":"2006","unstructured":"Mori, T. A., & Woodman, R. J. (2006). The independent effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors in humans. Current Opinion in Clinical Nutrition and Metabolic Care, 9(2), 95\u2013104.","journal-title":"Current Opinion in Clinical Nutrition and Metabolic Care"},{"issue":"6","key":"9325_CR22","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.ahj.2007.11.045","volume":"155","author":"M Wilhelm","year":"2008","unstructured":"Wilhelm, M., Tobias, R., Asskali, F., et al. (2008). Red blood cell omega-3 fatty acids and the risk of ventricular arrhythmias in patients with heart failure. American Heart Journal, 155(6), 971\u2013977. doi: 10.1016\/j.ahj.2007.11.045 .","journal-title":"American Heart Journal"},{"issue":"9","key":"9325_CR23","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.biopsych.2004.01.021","volume":"55","author":"N Frasure-Smith","year":"2004","unstructured":"Frasure-Smith, N., Lesperance, F., & Julien, P. (2004). Major depression is associated with lower omega-3 fatty acid levels in patients with recent acute coronary syndromes. Biological Psychiatry, 55(9), 891\u2013896. doi: 10.1016\/j.biopsych.2004.01.021S0006322304001076 .","journal-title":"Biological Psychiatry"},{"issue":"5","key":"9325_CR24","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0006-3223(97)00206-0","volume":"43","author":"M Peet","year":"1998","unstructured":"Peet, M., Murphy, B., Shay, J., & Horrobin, D. (1998). Depletion of omega-3 fatty acid levels in red blood cell membranes of depressive patients. Biological Psychiatry, 43(5), 315\u2013319.","journal-title":"Biological Psychiatry"},{"issue":"2\u20133","key":"9325_CR25","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0165-0327(97)00166-3","volume":"48","author":"R Edwards","year":"1998","unstructured":"Edwards, R., Peet, M., Shay, J., & Horrobin, D. (1998). Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients. Journal of Affective Disorders, 48(2\u20133), 149\u2013155.","journal-title":"Journal of Affective Disorders"},{"issue":"3","key":"9325_CR26","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0165-1781(99)00014-1","volume":"85","author":"M Maes","year":"1999","unstructured":"Maes, M., Christophe, A., Delanghe, J., Altamura, C., Neels, H., & Meltzer, H. Y. (1999). Lowered omega 3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients. Psychiatry Research, 85(3), 275\u2013291.","journal-title":"Psychiatry Research"},{"issue":"8","key":"9325_CR27","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1038\/sj.ejcn.1602413","volume":"60","author":"G Mamalakis","year":"2006","unstructured":"Mamalakis, G., Jansen, E., Cremers, H., Kiriakakis, M., Tsibinos, G., & Kafatos, A. (2006). Depression and adipose and serum cholesteryl ester polyunsaturated fatty acids in the survivors of the seven countries study population of Crete. European Journal of Clinical Nutrition, 60(8), 1016\u20131023. doi: 10.1038\/sj.ejcn.1602413 .","journal-title":"European Journal of Clinical Nutrition"},{"issue":"1","key":"9325_CR28","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.biopsych.2006.08.026","volume":"62","author":"RK McNamara","year":"2007","unstructured":"McNamara, R. K., Hahn, C. G., Jandacek, R., et al. (2007). Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder. Biological Psychiatry, 62(1), 17\u201324. doi: 10.1016\/j.biopsych.2006.08.026 .","journal-title":"Biological Psychiatry"},{"issue":"1","key":"9325_CR29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0165-0327(95)00092-5","volume":"38","author":"M Maes","year":"1996","unstructured":"Maes, M., Smith, R., Christophe, A., Cosyns, P., Desnyder, R., & Meltzer, H. (1996). Fatty acid composition in major depression: Decreased omega 3 fractions in cholesteryl esters and increased C20:4 omega 6\/C20:5 omega 3 ratio in cholesteryl esters and phospholipids. Journal of Affective Disorders, 38(1), 35\u201346.","journal-title":"Journal of Affective Disorders"},{"issue":"1","key":"9325_CR30","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/ajcn\/78.1.40","volume":"78","author":"H Tiemeier","year":"2003","unstructured":"Tiemeier, H., van Tuijl, H. R., Hofman, A., Kiliaan, A. J., & Breteler, M. M. B. (2003). Plasma fatty acid composition and depression are associated in the elderly: The Rotterdam Study. American Journal of Clinical Nutrition, 78(1), 40\u201346.","journal-title":"American Journal of Clinical Nutrition"},{"issue":"5","key":"9325_CR31","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1093\/ajcn\/87.5.1156","volume":"87","author":"C Feart","year":"2008","unstructured":"Feart, C., Peuchant, E., Letenneur, L., et al. (2008). Plasma eicosapentaenoic acid is inversely associated with severity of depressive symptomatology in the elderly: Data from the Bordeaux sample of the Three-City Study. American Journal of Clinical Nutrition, 87(5), 1156\u20131162.","journal-title":"American Journal of Clinical Nutrition"},{"issue":"7","key":"9325_CR32","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.jacc.2010.11.014","volume":"57","author":"WHW Tang","year":"2011","unstructured":"Tang, W. H. W., & Samara, M. A. (2011). Polyunsaturated Fatty acids in heart failure: Should we give more and give earlier? Journal of the American College of Cardiology, 57(7), 880\u2013883.","journal-title":"Journal of the American College of Cardiology"},{"issue":"4","key":"9325_CR33","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1590\/S0100-879X1998000400002","volume":"31","author":"PC Calder","year":"1998","unstructured":"Calder, P. C. (1998). Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Brazilian Journal of Medical and Biological Research, 31(4), 467\u2013490.","journal-title":"Brazilian Journal of Medical and Biological Research"},{"key":"9325_CR34","first-page":"50","volume":"18","author":"ATJ Heller","year":"2003","unstructured":"Heller, A. T. J., & Koch, T. (2003). Fish or chips? News in Physiological Sciences, 18, 50\u201354.","journal-title":"News in Physiological Sciences"},{"issue":"8","key":"9325_CR35","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0753-3322(02)00253-6","volume":"56","author":"AP Simopoulos","year":"2002","unstructured":"Simopoulos, A. P. (2002). The importance of the ratio of omega-6\/omega-3 essential fatty acids. Biomedicine & Pharmacotherapy, 56(8), 365\u2013379.","journal-title":"Biomedicine & Pharmacotherapy"},{"issue":"3","key":"9325_CR36","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/ajcn\/70.3.331","volume":"70","author":"JH Christensen","year":"1999","unstructured":"Christensen, J. H., Christensen, M. S., Dyerberg, J., & Schmidt, E. B. (1999). Heart rate variability and fatty acid content of blood cell membranes: A dose-response study with n-3 fatty acids. American Journal of Clinical Nutrition, 70(3), 331\u2013337.","journal-title":"American Journal of Clinical Nutrition"},{"issue":"12","key":"9325_CR37","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1093\/eurjhf\/hfq172","volume":"12","author":"S Ghio","year":"2010","unstructured":"Ghio, S., Scelsi, L., Latini, R., et al. (2010). Effects of n-3 polyunsaturated fatty acids and of rosuvastatin on left ventricular function in chronic heart failure: A substudy of GISSI-HF trial. European Journal of Heart Failure: Journal of the Working Group on Heart Failure of the European Society of Cardiology, 12(12), 1345\u20131353.","journal-title":"European Journal of Heart Failure : Journal of the Working Group on Heart Failure of the European Society of Cardiology"},{"issue":"7","key":"9325_CR38","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.jacc.2010.11.017","volume":"57","author":"S Nodari","year":"2011","unstructured":"Nodari, S., Triggiani, M., Campia, U., et al. (2011). Effects of n-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Functional Capacity in Patients With Dilated Cardiomyopathy. Journal of the American College of Cardiology, 57(7), 870\u2013879.","journal-title":"Journal of the American College of Cardiology"},{"issue":"7","key":"9325_CR39","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.4088\/JCP.v68n0712","volume":"68","author":"PY Lin","year":"2007","unstructured":"Lin, P. Y., & Su, K. P. (2007). A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids. The Journal of Clinical Psychiatry, 68(7), 1056\u20131061.","journal-title":"The Journal of Clinical Psychiatry"},{"issue":"2","key":"9325_CR40","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1017\/S0007114507824123","volume":"99","author":"AJ Richardson","year":"2008","unstructured":"Richardson, A. J. (2008). n-3 fatty acids and mood: The devil is in the detail. British Journal of Nutrition, 99(2), 221\u2013223. doi: 10.1017\/s0007114507824123 .","journal-title":"British Journal of Nutrition"},{"key":"9325_CR41","first-page":"98","volume":"2","author":"BM Ross","year":"2008","unstructured":"Ross, B. M. (2008). The emerging role of eicosapentaenoic acid as an important psychoactive natural product: Some answers but a lot more questions. Lipid Insights, 2, 98\u20137.","journal-title":"Lipid Insights"},{"issue":"4","key":"9325_CR42","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1079\/BJN2002689","volume":"88","author":"GC Burdge","year":"2002","unstructured":"Burdge, G. C., & Wootton, S. A. (2002). Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. British Journal of Nutrition, 88(4), 411\u2013420. doi: 10.1079\/bjn2002689 .","journal-title":"British Journal of Nutrition"},{"issue":"5","key":"9325_CR43","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1051\/rnd:2005047","volume":"45","author":"GC Burdge","year":"2005","unstructured":"Burdge, G. C., & Calder, P. C. (2005). Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reproduction Nutrition Development, 45(5), 581\u2013597. doi: 10.1051\/rnd:2005047 .","journal-title":"Reproduction Nutrition Development"},{"issue":"4","key":"9325_CR44","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1079\/BJN2002662","volume":"88","author":"GC Burdge","year":"2002","unstructured":"Burdge, G. C., Jones, A. E., & Wootton, S. A. (2002). Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men. British Journal of Nutrition, 88(4), 355\u2013363. doi: 10.1079\/bjn2002662 .","journal-title":"British Journal of Nutrition"},{"issue":"6","key":"9325_CR45","doi-asserted-by":"crossref","first-page":"1467S","DOI":"10.1093\/ajcn\/83.6.1467S","volume":"83","author":"LM Arterburn","year":"2006","unstructured":"Arterburn, L. M., Hall, E. B., & Oken, H. (2006). Distribution, interconversion, and dose response of n-3 fatty acids in humans. American Journal of Clinical Nutrition, 83(6), 1467S\u20131476S.","journal-title":"American Journal of Clinical Nutrition"},{"issue":"52","key":"9325_CR46","doi-asserted-by":"crossref","first-page":"37335","DOI":"10.1074\/jbc.274.52.37335","volume":"274","author":"HP Cho","year":"1999","unstructured":"Cho, H. P., Nakamura, M., & Clarke, S. D. (1999). Cloning, expression, and fatty acid regulation of the human delta-5 desaturase. Journal of Biological Chemistry, 274(52), 37335\u201337339.","journal-title":"Journal of Biological Chemistry"},{"issue":"4\u20135","key":"9325_CR47","first-page":"243","volume":"2","author":"SM Xie LaI","year":"2010","unstructured":"Xie LaI, S. M. (2010). Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study. Journal of Nutrigenetics and Nutrigenomics, 2(4\u20135), 243\u2013250.","journal-title":"Journal of Nutrigenetics and Nutrigenomics"},{"issue":"1\u20133","key":"9325_CR48","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jad.2009.04.007","volume":"120","author":"A Lalovic","year":"2010","unstructured":"Lalovic, A., Klempan, T., Sequeira, A., Luheshi, G., & Turecki, G. (2010). Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers. Journal of Affective Disorders, 120(1\u20133), 24\u201331. doi: 10.1016\/j.jad.2009.04.007 .","journal-title":"Journal of Affective Disorders"},{"issue":"9","key":"9325_CR49","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/sj.ejcn.1600455","volume":"51","author":"C BoltonSmith","year":"1997","unstructured":"BoltonSmith, C., Woodward, M., & Tavendale, R. (1997). Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet. European Journal of Clinical Nutrition, 51(9), 619\u2013624.","journal-title":"European Journal of Clinical Nutrition"},{"issue":"6","key":"9325_CR50","first-page":"1001","volume":"17","author":"A Bordoni","year":"1988","unstructured":"Bordoni, A., Biagi, P. L., Turchetto, E., & Hrelia, S. (1988). Aging influence on delta-6-desaturase activity and fatty-acid composition of rat-liver microsomes. Biochemistry International, 17(6), 1001\u20131009.","journal-title":"Biochemistry International"},{"issue":"3","key":"9325_CR51","first-page":"461","volume":"41","author":"JM Bourre","year":"1997","unstructured":"Bourre, J. M., & Piciotti, M. (1997). Alterations in eighteen-carbon saturated, monounsaturated and polyunsaturated fatty acid peroxisomal oxidation in mouse brain during development and aging. Biochemistry and Molecular Biology International, 41(3), 461\u2013468.","journal-title":"Biochemistry and Molecular Biology International"},{"issue":"1","key":"9325_CR52","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/0006-291X(89)92142-6","volume":"163","author":"S Hrelia","year":"1989","unstructured":"Hrelia, S., Bordoni, A., Celadon, M., Turchetto, E., Biagi, P. L., & Rossi, C. A. (1989). Age-related-changes in linoleate and alpha-linolenate desaturation by rat-liver microsomes. Biochemical and Biophysical Research Communications, 163(1), 348\u2013355.","journal-title":"Biochemical and Biophysical Research Communications"},{"issue":"4","key":"9325_CR53","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/BF02536313","volume":"28","author":"C Maniongui","year":"1993","unstructured":"Maniongui, C., Blond, J. P., Ulmann, L., Durand, G., Poisson, J. P., & Bezard, J. (1993). Age-related-changes in delta-6 and delta-5 desaturase activities in rat-liver microsomes. Lipids, 28(4), 291\u2013297.","journal-title":"Lipids"},{"issue":"4","key":"9325_CR54","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/0300-9084(96)88138-7","volume":"77","author":"R Perichon","year":"1995","unstructured":"Perichon, R., & Bourre, J. M. (1995). Peroxisomal beta-oxidation activity and catalase activity during development and aging in mouse-liver. Biochimie, 77(4), 288\u2013293.","journal-title":"Biochimie"},{"key":"9325_CR55","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1093\/ajcn\/84.6.1308","volume":"84","author":"KHR Appleton","year":"2006","unstructured":"Appleton, K. H. R., Gunnell, D., Peters, T., Rogers, P., Kessler, D., & Ness, A. (2006). Effects of n-3 long-chain polyunsaturated fatty acids on depressed mood: Systemic review of published trials. American Journal of Clinical Nutrition, 84, 1308\u20131316.","journal-title":"American Journal of Clinical Nutrition"},{"issue":"3","key":"9325_CR56","doi-asserted-by":"crossref","first-page":"757","DOI":"10.3945\/ajcn.2009.28313","volume":"91","author":"KM Appleton","year":"2010","unstructured":"Appleton, K. M., Rogers, P. J., & Ness, A. R. (2010). Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood. American Journal of Clinical Nutrition, 91(3), 757\u2013770. doi: 10.3945\/ajcn.2009.28313 .","journal-title":"American Journal of Clinical Nutrition"},{"issue":"9","key":"9325_CR57","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1001\/jama.2010.191","volume":"303","author":"RM Carney","year":"2010","unstructured":"Carney, R. M., Freedland, K. E., & Steinmeyer, B. C. (2010). Omega-3 fatty acids for CHD with depression reply. Jama-Journal of the American Medical Association, 303(9), 836.","journal-title":"Jama-Journal of the American Medical Association"},{"key":"9325_CR58","doi-asserted-by":"crossref","unstructured":"Lesperance, F., Frasure-Smith, N., St-Andre, E., Turecki, G., Lesperance, P., & Wisniewski, S. R. (2010). The efficacy of omega-3 supplementation for major depression: A randomized controlled trial. The Journal of Clinical Psychiatry. doi: 10.4088\/JCP.10m05966blu .","DOI":"10.4088\/JCP.10m05966blu"},{"key":"9325_CR59","doi-asserted-by":"crossref","unstructured":"Kromhout, D., Giltay, E. J., & Geleijnse, J. M. (2010). n\u20133 Fatty acids and cardiovascular events after myocardial infarction. The New England Journal of Medicine. doi: 10.1056\/NEJMoa1003603 .","DOI":"10.1056\/NEJMoa1003603"}],"container-title":["Journal of Cardiovascular Translational Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12265-011-9325-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12265-011-9325-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12265-011-9325-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T23:57:08Z","timestamp":1560902228000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12265-011-9325-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,1]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["9325"],"URL":"https:\/\/doi.org\/10.1007\/s12265-011-9325-8","relation":{},"ISSN":["1937-5387","1937-5395"],"issn-type":[{"value":"1937-5387","type":"print"},{"value":"1937-5395","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,1]]}}}