{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:31:48Z","timestamp":1760985108214},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T00:00:00Z","timestamp":1404864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. of Cardiovasc. Trans. Res."],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1007\/s12265-014-9574-4","type":"journal-article","created":{"date-parts":[[2014,7,8]],"date-time":"2014-07-08T14:59:01Z","timestamp":1404831541000},"page":"570-580","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Pharmacological Attenuation of Myocardial Reperfusion Injury in a Closed-Chest Porcine Model: a Systematic Review"],"prefix":"10.1007","volume":"7","author":[{"given":"Sarah","family":"Ekel\u00f8f","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Skov","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail","family":"G\u00f6genur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,7,9]]},"reference":[{"key":"9574_CR1","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1056\/NEJMra071667","volume":"357","author":"DM Yellon","year":"2007","unstructured":"Yellon, D. M., & Hausenloy, D. J. (2007). Myocardial reperfusion injury. New England Journal of Medicine, 357, 1121\u20131135.","journal-title":"New England Journal of Medicine"},{"key":"9574_CR2","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1161\/01.CIR.0000016602.96363.36","volume":"105","author":"S Verma","year":"2002","unstructured":"Verma, S., Fedak, P. W., Weisel, R. D., et al. (2002). Fundamentals of reperfusion injury for the clinical cardiologist. Circulation, 105, 2332\u20132336.","journal-title":"Circulation"},{"key":"9574_CR3","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1517\/14728214.12.3.367","volume":"12","author":"ER Gross","year":"2007","unstructured":"Gross, E. R., & Gross, G. J. (2007). Pharmacologic therapeutics for cardiac reperfusion injury. Expert Opinion on Emerging Drugs, 12, 367\u2013388.","journal-title":"Expert Opinion on Emerging Drugs"},{"key":"9574_CR4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1001\/jama.297.17.1881-b","volume":"297","author":"PW Armstrong","year":"2007","unstructured":"Armstrong, P. W., Granger, C. B., Adams, P. X., et al. (2007). Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: a randomized controlled trial. JAMA, 297, 43\u201351.","journal-title":"JAMA"},{"key":"9574_CR5","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1161\/CIRCULATIONAHA.107.759167","volume":"117","author":"E Bates","year":"2008","unstructured":"Bates, E., Bode, C., Costa, M., et al. (2008). Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction. Direct inhibition of delta-protein kinase c enzyme to limit total infarct size in acute myocardial infarction. Circulation, 117, 886\u2013896.","journal-title":"Circulation"},{"key":"9574_CR6","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1056\/NEJMoa071142","volume":"359","author":"C Piot","year":"2008","unstructured":"Piot, C., Croisille, P., Staat, P., et al. (2008). Effect of cyclosporine on reperfusion in acute myocardial infarction. New England Journal of Medicine, 359, 473\u2013481.","journal-title":"New England Journal of Medicine"},{"key":"9574_CR7","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1161\/01.CIR.89.5.1982","volume":"89","author":"JT Flaherty","year":"1994","unstructured":"Flaherty, J. T., Pitt, B., Gruber, J. W., et al. (1994). Recombinant human superoxide dismutase (h-SOD) fails to improve recovery of ventricular function in patients undergoing coronary angioplasty for acute myocardial infarction. Circulation, 89, 1982\u20131991.","journal-title":"Circulation"},{"key":"9574_CR8","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.vascn.2009.05.007","volume":"60","author":"A P\u00e9rez de Prado","year":"2009","unstructured":"P\u00e9rez de Prado, A., Cuellas-Ram\u00f3n, C., Regueiro-Purri\u00f1os, M., et al. (2009). Closed-chest experimental porcine model of acute myocardial infarction-reperfusion. Journal of Pharmacological and Toxicological Methods, 60, 301\u2013306.","journal-title":"Journal of Pharmacological and Toxicological Methods"},{"key":"9574_CR9","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/ccd.21329","volume":"71","author":"Y Suzuki","year":"2008","unstructured":"Suzuki, Y., Lyons, J. K., Yeung, A. C., et al. (2008). In vivo porcine model of reperfused myocardial infarction: in situ double staining to measure precise infarct area\/area at risk. Catheterization and Cardiovascular Interventions, 71, 100\u2013107.","journal-title":"Catheterization and Cardiovascular Interventions"},{"key":"9574_CR10","first-page":"14","volume":"40","author":"GA Krombach","year":"2005","unstructured":"Krombach, G. A., Kinzel, S., Mahnken, A. H., et al. (2005). Minimally invasive close-chest method for creating reperfused or occlusive myocardial infarction in swine. Investigative Radiology, 40, 14\u201318.","journal-title":"Investigative Radiology"},{"key":"9574_CR11","first-page":"1807","volume":"174","author":"S Busch","year":"2012","unstructured":"Busch, S., Halladin, N. L., Jensen, S. E., Rosenberg, J., et al. (2012). Closed-chest porcine model is superior in intervention studies of ischaemia reperfusion injury. Ugeskrift for Laeger, 174, 1807\u20131810.","journal-title":"Ugeskrift for Laeger"},{"key":"9574_CR12","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jcin.2009.10.015","volume":"3","author":"I Rentoukas","year":"2010","unstructured":"Rentoukas, I., Giannopoulos, G., Kaoukis, A., et al. (2010). Cardioprotective role of remote ischemic periconditioning in primary percutaneous coronary intervention. JACC Cardiovascular Interventions, 3, 49\u201355.","journal-title":"JACC Cardiovascular Interventions"},{"key":"9574_CR13","doi-asserted-by":"crossref","first-page":"W65","DOI":"10.7326\/0003-4819-151-4-200908180-00136","volume":"151","author":"A Liberati","year":"2009","unstructured":"Liberati, A., Altman, D. G., Tetzlaff, J., et al. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Annals of Internal Medicine, 151, W65\u2013W94.","journal-title":"Annals of Internal Medicine"},{"key":"9574_CR14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1471-2261-10-45","volume":"10","author":"J Pals van der","year":"2010","unstructured":"van der Pals, J., Koul, S., Andersson, P., et al. (2010). Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in the porcine ischemia-reperfusion model. BMC Cardiovascular Disorders, 10, 45.","journal-title":"BMC Cardiovascular Disorders"},{"key":"9574_CR15","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.cardiores.2007.07.016","volume":"76","author":"Y Banz","year":"2007","unstructured":"Banz, Y., Hess, O. M., Robson, S. C., et al. (2007). Attenuation of myocardial reperfusion injury in pigs by Mirocept, a membrane-targeted complement inhibitor derived for human CR1. Cardiovascular Research, 76, 482\u2013493.","journal-title":"Cardiovascular Research"},{"key":"9574_CR16","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1093\/eurheartj\/ehi421","volume":"26","author":"Y Banz","year":"2005","unstructured":"Banz, Y., Hess, O. M., Robson, S. C., et al. (2005). Locally targeted cytoprotection with dextran sulfate attenuates experimental porcine myocardial ischemia\/reperfusion injury. European Heart Journal, 26, 2334\u20132343.","journal-title":"European Heart Journal"},{"key":"9574_CR17","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000336485","volume":"121","author":"Y Banz","year":"2012","unstructured":"Banz, Y., Hess, O. M., Meier, P., et al. (2012). Evaluation of multimeric tyrosine-o-sulfate as a cytoprotectant in an in vivo model of acute myocardial infarction in pigs. Cardiology, 121, 59\u201370.","journal-title":"Cardiology"},{"key":"9574_CR18","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1161\/01.CIR.0000101682.24138.36","volume":"108","author":"K Inagaki","year":"2003","unstructured":"Inagaki, K., Chen, L., Ikeno, F., et al. (2003). Inhibition of delta-protein kinase c protects against reperfusion injury of the ischemic heart in vivo. Circulation, 108, 2304\u20132307.","journal-title":"Circulation"},{"key":"9574_CR19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3389\/fphys.2011.00027","volume":"2","author":"H Ishiguro","year":"2011","unstructured":"Ishiguro, H., Horiba, M., Takenaka, H., et al. (2011). A single intracoronary injection of midkine reduces ischemia\/reperfusion injury in swine hearts: a novel therapeutic approach for acute coronary syndrome. Frontiers in Physiology, 2, 27.","journal-title":"Frontiers in Physiology"},{"key":"9574_CR20","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.cyto.2010.06.003","volume":"51","author":"FS Angeli","year":"2010","unstructured":"Angeli, F. S., Smith, C., Amabile, N., et al. (2010). Granulocyte colony stimulating factor in myocardial infarction with low ejection fraction. Cytokine, 51, 278\u2013285.","journal-title":"Cytokine"},{"key":"9574_CR21","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1177\/1074248411407636","volume":"17","author":"LO Karlsson","year":"2012","unstructured":"Karlsson, L. O., Bergh, N., & Grip, L. (2012). Cyclosporine a, 2,5\u00a0mg\/kg, does not reduce myocardial infarct size in a porcine model of ischemia and reperfusion. Journal of Cardiovascular Pharmacology and Therapeutics, 17, 159\u2013163.","journal-title":"Journal of Cardiovascular Pharmacology and Therapeutics"},{"key":"9574_CR22","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.ejphar.2010.10.069","volume":"651","author":"LO Karlsson","year":"2011","unstructured":"Karlsson, L. O., Grip, L., Bissessar, E., et al. (2011). Opioid receptor agonist Eribis peptide 94 reduces infarct size in different porcine models for myocardial ischaemia and reperfusion. European Journal of Pharmacology, 651, 146\u2013151.","journal-title":"European Journal of Pharmacology"},{"key":"9574_CR23","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/01.fjc.0000133675.08745.d2","volume":"44","author":"J Odenstedt","year":"2004","unstructured":"Odenstedt, J., Mansson, C., & Grip, L. (2004). Failure to demonstrate myocardial protective effects of the ultra short-acting calcium antagonist clevidipine in a closed-chest reperfusion porcine model. Journal of Cardiovascular Pharmacology, 44, 407\u2013415.","journal-title":"Journal of Cardiovascular Pharmacology"},{"key":"9574_CR24","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.acvd.2011.02.004","volume":"104","author":"B Han","year":"2011","unstructured":"Han, B., Zhang, X., Zhang, Q., et al. (2011). Protective effects of salvianolate on microvascular flow in a porcine model of myocardial ischaemia and reperfusion. Archives of Cardiovascular Diseases, 104, 313\u2013324.","journal-title":"Archives of Cardiovascular Diseases"},{"key":"9574_CR25","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1161\/01.RES.66.5.1294","volume":"66","author":"U N\u00e4slund","year":"1990","unstructured":"N\u00e4slund, U., H\u00e4ggmark, S., Johansson, G., et al. (1990). Limitation of myocardial infarct size by superoxide dismutase as an adjunct to reperfusion after different durations of coronary occlusion in the pig. Circulation Research, 66, 1294\u20131301.","journal-title":"Circulation Research"},{"key":"9574_CR26","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/cvr\/26.2.170","volume":"26","author":"U N\u00e4slund","year":"1992","unstructured":"N\u00e4slund, U., H\u00e4ggmark, S., Johansson, G., et al. (1992). Effects of reperfusion and superoxide dismutase on myocardial infarct size in a closed chest pig model. Cardiovascular Research, 26, 170\u2013178.","journal-title":"Cardiovascular Research"},{"key":"9574_CR27","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1007\/s00395-011-0224-6","volume":"106","author":"M Lichtenauer","year":"2011","unstructured":"Lichtenauer, M., Mildner, M., Hoetzenecker, K., et al. (2011). Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodeling after acute myocardial infarction: a preclinical study. Basic Research in Cardiology, 106, 1283\u20131297.","journal-title":"Basic Research in Cardiology"},{"key":"9574_CR28","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/BF02190543","volume":"86","author":"RA Tio","year":"1991","unstructured":"Tio, R. A., Tob\u00e9, T. J., Bel, K. J., et al. (1991). Beneficial effects of bradykinin on porcine ischemic myocardium. Basic Research in Cardiology, 86, 107\u2013116.","journal-title":"Basic Research in Cardiology"},{"key":"9574_CR29","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/00005344-199203000-00017","volume":"19","author":"J Wijngaarden Van","year":"1992","unstructured":"Van Wijngaarden, J., Tob\u00e9, T. J., Weersink, E. G., et al. (1992). Effects of early angiotensin-converting enzyme inhibition in a pig model of myocardial ischemia and reperfusion. Journal of Cardiovascular Pharmacology, 19, 408\u2013416.","journal-title":"Journal of Cardiovascular Pharmacology"},{"key":"9574_CR30","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0002-9343(88)90207-0","volume":"84","author":"PA DeGraeff","year":"1988","unstructured":"DeGraeff, P. A., de Langen, C. D., van Gilst, W. H., et al. (1988). Protective effects of captopril against ischemia\/reperfusion-induced ventricular arrhythmias in vitro and in vivo. American Journal of Medicine, 84, 67\u201374.","journal-title":"American Journal of Medicine"},{"key":"9574_CR31","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/BF00271069","volume":"98","author":"LE Thornell","year":"1992","unstructured":"Thornell, L. E., Holmbom, B., Eriksson, A., et al. (1992). Enzyme and immunohistochemical assessment of myocardial damage after ischaemia and reperfusion in a closed-chest pig model. Histochemistry, 98, 341\u2013352.","journal-title":"Histochemistry"},{"key":"9574_CR32","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10741-007-9025-2","volume":"12","author":"JM Downey","year":"2007","unstructured":"Downey, J. M., Davis, A. M., & Cohen, M. V. (2007). Signaling pathways in ischemic preconditioning. Heart Failure Reviews, 12, 181\u2013188.","journal-title":"Heart Failure Reviews"},{"key":"9574_CR33","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/sj.bjp.0704548","volume":"135","author":"GF Baxter","year":"2002","unstructured":"Baxter, G. F., & Ebrahim, Z. (2002). Role of bradykinin in preconditioning and protection of the ischaemic myocardium. British Journal of Pharmacology, 135, 843\u2013854.","journal-title":"British Journal of Pharmacology"},{"key":"9574_CR34","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.2174\/092986710791331077","volume":"17","author":"F Correa","year":"2010","unstructured":"Correa, F., Mart\u00ednez-Abundis, E., Hern\u00e1ndez-Res\u00e9ndiz, S., et al. (2010). Pharmacological strategies to contend against myocardial reperfusion damage: diverse chemicals for multiple targets. Current Medicinal Chemistry, 17, 2261\u20132273.","journal-title":"Current Medicinal Chemistry"},{"key":"9574_CR35","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1291\/hypres.24.179","volume":"24","author":"LX Wang","year":"2001","unstructured":"Wang, L. X., Ideishi, M., Yahiro, E., et al. (2001). Mechanism of the cardioprotective effect of inhibition of the rennin-angiotensin system on ischemia\/reperfusion-induced myocardial injury. Hypertension Research, 24, 179\u2013187.","journal-title":"Hypertension Research"},{"key":"9574_CR36","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/hr.2010.82","volume":"33","author":"AJ Manolis","year":"2010","unstructured":"Manolis, A. J., Marketou, M. E., Gavras, I., et al. (2010). Cardioprotective properties of bradykinin: role of the B(2) receptor. Hypertension Research, 33, 772\u2013777.","journal-title":"Hypertension Research"},{"key":"9574_CR37","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/MCA.0b013e3283526a7d","volume":"23","author":"XJ Ma","year":"2012","unstructured":"Ma, X. J., Yin, H. J., Guo, C. Y., et al. (2012). Ischemic postconditioning through percutaneous transluminal coronary angioplasty in pigs: roles of PI3K activation. Coronary Artery Disease, 23, 245\u2013250.","journal-title":"Coronary Artery Disease"},{"key":"9574_CR38","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jacc.2006.06.080","volume":"49","author":"H Otaka","year":"2007","unstructured":"Otaka, H., Shite, J., Paredes, O. L., et al. (2007). Catheter-based transcoronary myocardial hypothermia attenuates arrhythmia and myocardial necrosis in pigs with acute myocardial infarction. Journal of the American College of Cardiology, 49, 250\u2013260.","journal-title":"Journal of the American College of Cardiology"},{"key":"9574_CR39","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1161\/CIRCULATIONAHA.113.001904","volume":"128","author":"R Hinkel","year":"2013","unstructured":"Hinkel, R., Penzkofer, D., Z\u00fchlke, S., et al. (2013). Inhibition of MicroRNA-92a protects against ischemia\/reperfusion injury in a large-animal model. Circulation, 128, 1066\u20131075.","journal-title":"Circulation"},{"key":"9574_CR40","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1161\/CIRCULATIONAHA.112.115089","volume":"126","author":"Y Ogura","year":"2012","unstructured":"Ogura, Y., Ouchi, N., Ohashi, K., et al. (2012). Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models. Circulation, 126, 1728\u20131738.","journal-title":"Circulation"},{"key":"9574_CR41","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1152\/jappl.1998.84.6.2190","volume":"84","author":"F Grund","year":"1998","unstructured":"Grund, F., Sommerschild, H. T., Kirkeboen, K. A., et al. (1998). A new approach to normalize myocardial temperature in the open-chest model. Journal of Applied Physiology, 84, 2190\u20132197.","journal-title":"Journal of Applied Physiology"},{"key":"9574_CR42","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/BF03017409","volume":"49","author":"R Kato","year":"2002","unstructured":"Kato, R., & Fo\u00ebx, P. (2002). Myocardial protection by anaesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists. Canadian Journal of Anaesthesia, 49, 777\u2013791.","journal-title":"Canadian Journal of Anaesthesia"},{"key":"9574_CR43","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1017\/S0265021505001080","volume":"22","author":"NC Weber","year":"2005","unstructured":"Weber, N. C., Preckel, B., & Schlack, W. (2005). The effect of anaesthetics on the myocardium\u2014new insights into myocardial protection. European Journal of Anaesthesiology, 22, 647\u2013657.","journal-title":"European Journal of Anaesthesiology"},{"key":"9574_CR44","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/bja\/82.4.622","volume":"82","author":"S Ross","year":"1999","unstructured":"Ross, S., & Fo\u00ebx, P. (1999). Protective effects of anaesthetics in reversible and irreversible ischaemia-reperfusion injury. British Journal of Anaesthesia, 82, 622\u2013632.","journal-title":"British Journal of Anaesthesia"},{"key":"9574_CR45","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1111\/j.1399-6576.2008.01755.x","volume":"52","author":"JR Larsen","year":"2008","unstructured":"Larsen, J. R., Aagaard, S., Lie, R. H., et al. (2008). Sevoflurane improves myocardial ischaemic tolerance in a closed-chest porcine model. Acta Anaesthesiologica Scandinavica, 52, 1400\u20131410.","journal-title":"Acta Anaesthesiologica Scandinavica"},{"key":"9574_CR46","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00000542-200207000-00004","volume":"97","author":"M Zaugg","year":"2002","unstructured":"Zaugg, M., Lucchinetti, E., Spahn, D. R., et al. (2002). Differential effects of anaesthetics on mitochondrial K(ATP) channel activity and cardiomyocyte protection. Anesthesiology, 97, 15\u201323.","journal-title":"Anesthesiology"},{"key":"9574_CR47","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1097\/00000539-200006000-00007","volume":"90","author":"A Szekely","year":"2000","unstructured":"Szekely, A., Heindl, B., Zahler, S., et al. (2000). Nonuniform behavior of intravenous anaesthetics on postischemic adhesion of neutrophils in the guinea pig heart. Anesthesia and Analgesia, 90, 1293\u20131300.","journal-title":"Anesthesia and Analgesia"},{"key":"9574_CR48","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3349\/ymj.2010.51.2.187","volume":"51","author":"HS Kim","year":"2010","unstructured":"Kim, H. S., Hwang, K. C., & Park, W. K. (2010). Cardio protection via modulation of calcium homeostasis by thiopental in hypoxia-reoxygenated neonatal rat cardiomyocytes. Yonsei Medical Journal, 51, 187\u2013196.","journal-title":"Yonsei Medical Journal"},{"key":"9574_CR49","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/cvr\/21.7.537","volume":"21","author":"D Garcia-Dorado","year":"1987","unstructured":"Garcia-Dorado, D., Th\u00e9roux, P., Elizaga, J., et al. (1987). Myocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusion. Cardiovascular Research, 21, 537\u2013544.","journal-title":"Cardiovascular Research"},{"key":"9574_CR50","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1007\/BF01908144","volume":"79","author":"HH Klein","year":"1984","unstructured":"Klein, H. H., Schubothe, M., Nebendahl, K., et al. (1984). Temporal and spatial development of infarcts in porcine hearts. Basic Research in Cardiology, 79, 440\u2013447.","journal-title":"Basic Research in Cardiology"},{"key":"9574_CR51","doi-asserted-by":"crossref","first-page":"13G","DOI":"10.1016\/0002-9149(93)90102-I","volume":"72","author":"KA Reimer","year":"1993","unstructured":"Reimer, K. A., Vander Heide, R. S., & Richard, V. J. (1993). Reperfusion in acute myocardial infarction: effect of timing and modulating factors in experimental models. American Journal of Cardiology, 72, 13G\u201321G.","journal-title":"American Journal of Cardiology"},{"key":"9574_CR52","first-page":"522","volume":"121","author":"MT Vivaldi","year":"1985","unstructured":"Vivaldi, M. T., Kloner, R. A., & Schoen, F. J. (1985). Triphenyltetrazolium staining of irreversible ischemic injury following coronary artery occlusion in rats. American Journal of Pathology, 121, 522\u2013530.","journal-title":"American Journal of Pathology"},{"key":"9574_CR53","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1161\/01.CIR.98.10.1006","volume":"98","author":"CE Rochitte","year":"1998","unstructured":"Rochitte, C. E., Lima, J. A., Bluemke, D. A., et al. (1998). Magnitude and time course of microvascular obstruction and tissue injury after acute myocardial infarction. Circulation, 98, 1006\u20131014.","journal-title":"Circulation"},{"key":"9574_CR54","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1177\/1074248411412378","volume":"16","author":"AE Arai","year":"2011","unstructured":"Arai, A. E. (2011). Magnetic resonance imaging for area at risk, myocardial infarction, and myocardial salvage. Journal of Cardiovascular Pharmacology and Therapeutics, 16, 313\u2013320.","journal-title":"Journal of Cardiovascular Pharmacology and Therapeutics"},{"key":"9574_CR55","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1161\/01.CIR.100.19.1992","volume":"100","author":"RJ Kim","year":"1999","unstructured":"Kim, R. J., Fieno, D. S., Parrish, T. B., et al. (1999). Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation, 100, 1992\u20132002.","journal-title":"Circulation"},{"key":"9574_CR56","first-page":"321","volume":"16","author":"RJ Gibbons","year":"2011","unstructured":"Gibbons, R. J. (2011). Tc-99m SPECT sestamibi for the measurement of infarct size. Pharmacology and Therapeutics, 16, 321\u2013331.","journal-title":"Pharmacology and Therapeutics"},{"key":"9574_CR57","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.hlc.2012.11.016","volume":"22","author":"N Ahmed","year":"2013","unstructured":"Ahmed, N., Carrick, D., Layland, J., et al. (2013). The role of cardiac magnetic resonance imaging (MRI) in acute myocardial infarction (AMI). Heart, Lung & Circulation, 22, 243\u2013255.","journal-title":"Heart, Lung & Circulation"},{"key":"9574_CR58","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/ehjci\/jes142","volume":"14","author":"JF Ubachs","year":"2013","unstructured":"Ubachs, J. F., Engblom, H., Koul, S., et al. (2013). Myocardium at risk can be determined by ex vivo T2-weighted magnetic resonance imaging even in the presence of gadolinium: comparison to myocardial perfusion single photon emission computed tomography. European Heart Journal - Cardiovascular Imaging, 14, 261\u2013268.","journal-title":"European Heart Journal - Cardiovascular Imaging"},{"key":"9574_CR59","author":"S Koudstaal","year":"2014","unstructured":"Koudstaal, S., Jansen of Lorkeers, S., Gho, J. M., et al. (2014). Myocardial Infarction and functional outcome assessment in pigs. Journal of Visualized Experiments. doi: 10.3791\/51269 .","journal-title":"Journal of Visualized Experiments"},{"key":"9574_CR60","doi-asserted-by":"crossref","first-page":"H1078","DOI":"10.1152\/ajpheart.00801.2013","volume":"306","author":"CH Chen","year":"2014","unstructured":"Chen, C. H., Chang, M. Y., Wang, S. S., et al. (2014). Injection of autologous bone marrow cells in hyaluronan hydrogel improves cardiac performance after infarction in pigs. American Journal of Physiology - Heart and Circulatory Physiology, 306, H1078\u2013H1086.","journal-title":"American Journal of Physiology - Heart and Circulatory Physiology"},{"key":"9574_CR61","author":"PROTECTION AMI Investigators","year":"2014","unstructured":"PROTECTION AMI Investigators. (2014). Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI randomized controlled trial. European Heart Journal. doi: 10.1093\/eurheartj\/ehu177 .","journal-title":"European Heart Journal"},{"key":"9574_CR62","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/S0002-9149(01)02112-9","volume":"88","author":"T Kurz","year":"2001","unstructured":"Kurz, T., Sch\u00e4fer, U., Dendorfer, A., et al. (2001). Effects of intracoronary low-dose enalaprilat as an adjunct to primary percutaneous transluminal coronary angiography in acute myocardial infarction. American Journal of Cardiology, 88, 1351\u20131357.","journal-title":"American Journal of Cardiology"},{"key":"9574_CR63","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0140-6736(12)60916-7","volume":"381","author":"G Heusch","year":"2013","unstructured":"Heusch, G. (2013). Cardioprotection: chances and challenges of its translation to the clinic. Lancet, 381, 166\u2013175.","journal-title":"Lancet"},{"key":"9574_CR64","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s00395-008-0743-y","volume":"103","author":"T Miura","year":"2008","unstructured":"Miura, T., & Miki, T. (2008). Limitation of myocardial infarct size in the clinical setting: current status and challenges in translating animal experiments into clinical therapy. Basic Research in Cardiology, 103, 501\u2013513.","journal-title":"Basic Research in Cardiology"}],"container-title":["Journal of Cardiovascular Translational Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12265-014-9574-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12265-014-9574-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12265-014-9574-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T14:39:54Z","timestamp":1565620794000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12265-014-9574-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,9]]},"references-count":64,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["9574"],"URL":"https:\/\/doi.org\/10.1007\/s12265-014-9574-4","relation":{},"ISSN":["1937-5387","1937-5395"],"issn-type":[{"value":"1937-5387","type":"print"},{"value":"1937-5395","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,9]]}}}