{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:46:56Z","timestamp":1768456016224,"version":"3.49.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T00:00:00Z","timestamp":1680739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T00:00:00Z","timestamp":1680739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Universiti Malaya Faculty Research Grant","award":["GPF053B-2020"],"award-info":[{"award-number":["GPF053B-2020"]}]},{"name":"Private Funding","award":["PV005-2022"],"award-info":[{"award-number":["PV005-2022"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. of Cardiovasc. Trans. Res."],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1007\/s12265-023-10375-9","type":"journal-article","created":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T13:05:29Z","timestamp":1680786329000},"page":"1110-1122","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessing Complex Left Ventricular Adaptations in Aortic Stenosis Using Personalized 3D\u2009+\u2009time Cardiac MRI Modeling"],"prefix":"10.1007","volume":"16","author":[{"given":"Shoon Hui","family":"Chuah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nor Ashikin","family":"Md Sari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li Kuo","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yin Kia","family":"Chiam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bee Ting","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang Faridah","family":"Abdul Aziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeyaraaj","family":"Jeyabalan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khairunnisa","family":"Hasikin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2487-3933","authenticated-orcid":false,"given":"Yih Miin","family":"Liew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,4,6]]},"reference":[{"issue":"20","key":"10375_CR1","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1161\/CIRCULATIONAHA.118.033408","volume":"137","author":"E Braunwald","year":"2018","unstructured":"Braunwald E. Aortic stenosis: then and now. Circulation. 2018;137(20):2099\u2013100.","journal-title":"Circulation"},{"issue":"3","key":"10375_CR2","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.echo.2020.10.014","volume":"34","author":"F Fortuni","year":"2021","unstructured":"Fortuni F, Butcher SC, van der Kley F, Lustosa RP, Karalis I, de Weger A, Priori SG, van der Bijl P, Bax JJ, Delgado V. Left ventricular myocardial work in patients with severe aortic stenosis. J Am Soc Echocardiogr. 2021;34(3):257\u201366.","journal-title":"J Am Soc Echocardiogr"},{"issue":"1","key":"10375_CR3","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.jcmg.2018.08.040","volume":"12","author":"JS Dahl","year":"2019","unstructured":"Dahl JS, Magne J, Pellikka PA, Donal E, Marwick TH. Assessment of subclinical left ventricular dysfunction in aortic stenosis. JACC Cardiovasc Imaging. 2019;12(1):163\u201371.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"2","key":"10375_CR4","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.ijcard.2011.02.026","volume":"159","author":"P Faggiano","year":"2012","unstructured":"Faggiano P, Frattini S, Zilioli V, Rossi A, Nistri S, Dini FL, Lorusso R, Tomasi C, Dei Cas L. Prevalence of comorbidities and associated cardiac diseases in patients with valve aortic stenosis Potential implications for the decision-making process. Int J Cardiol. 2012;159(2):94\u20139.","journal-title":"Int J Cardiol"},{"issue":"5","key":"10375_CR5","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1093\/ehjci\/jex166","volume":"19","author":"F Levy","year":"2018","unstructured":"Levy F, Bohbot Y, Sanhadji K, Rusinaru D, Ringle A, Delpierre Q, Smaali S, Gun M, Marechaux S, Tribouilloy C. Impact of pulmonary hypertension on long-term outcome in patients with severe aortic stenosis. Eur Heart J-Cardiovasc Imaging. 2018;19(5):553\u201361.","journal-title":"Eur Heart J-Cardiovasc Imaging"},{"issue":"20","key":"10375_CR6","doi-asserted-by":"publisher","first-page":"2019","DOI":"10.1016\/j.jcin.2018.07.019","volume":"11","author":"Y Ahmad","year":"2018","unstructured":"Ahmad Y, G\u00f6tberg M, Cook C, Howard JP, Malik I, Mikhail G, Frame A, Petraco R, Rajkumar C, Demir O. Coronary hemodynamics in patients with severe aortic stenosis and coronary artery disease undergoing transcatheter aortic valve replacement: implications for clinical indices of coronary stenosis severity. JACC Cardiovasc Interventions. 2018;11(20):2019\u201331.","journal-title":"JACC Cardiovasc Interventions"},{"key":"10375_CR7","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.amjcard.2021.03.036","volume":"150","author":"S Aldrugh","year":"2021","unstructured":"Aldrugh S, Valle JE, Parker MW, Harrington CM, Aurigemma GP. Prevalence of left ventricular hypertrophy caused by systemic hypertension preceding the development of severe aortic stenosis. Am J Cardiol. 2021;150:89\u201394.","journal-title":"Am J Cardiol"},{"issue":"1","key":"10375_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1532-429X-14-50","volume":"14","author":"MR Dweck","year":"2012","unstructured":"Dweck MR, Joshi S, Murigu T, Gulati A, Alpendurada F, Jabbour A, Maceira A, Roussin I, Northridge DB, Kilner PJ. Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2012;14(1):1\u20139.","journal-title":"J Cardiovasc Magn Reson"},{"key":"10375_CR9","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1007\/s12350-019-01706-y","volume":"28","author":"W Zhou","year":"2021","unstructured":"Zhou W, Bajaj N, Gupta A, Sun Y-P, Divakaran S, Bibbo C, Hainer J, Taqueti V, Dorbala S, Blankstein R. Coronary microvascular dysfunction, left ventricular remodeling, and clinical outcomes in aortic stenosis. J Nucl Cardiol. 2021;28:579\u201388.","journal-title":"J Nucl Cardiol"},{"issue":"10","key":"10375_CR10","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1093\/ehjci\/jeac018","volume":"23","author":"J Stassen","year":"2022","unstructured":"Stassen J, Ewe SH, Hirasawa K, Butcher SC, Singh GK, Amanullah MR, Sin KY, Ding ZP, Pio SM, Chew NW. Left ventricular remodelling patterns in patients with moderate aortic stenosis. Eur Heart J-Cardiovasc Imaging. 2022;23(10):1326\u201335.","journal-title":"Eur Heart J-Cardiovasc Imaging"},{"key":"10375_CR11","doi-asserted-by":"crossref","unstructured":"Klein AL, Ramchand J, Nagueh SF. Aortic stenosis and diastolic dysfunction: partners in crime. American College of Cardiology Foundation Washington DC; 2020.","DOI":"10.1016\/j.jacc.2020.10.034"},{"issue":"4","key":"10375_CR12","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1111\/echo.13474","volume":"34","author":"EJ Cho","year":"2017","unstructured":"Cho EJ, Park SJ, Kim EK, Lee GY, Chang SA, Choi JO, Lee SC, Park SW. Effects of increased left ventricular wall thickness on the myocardium in severe aortic stenosis with normal left ventricular ejection fraction: two- and three-dimensional multilayer speckle tracking echocardiography. Echocardiography. 2017;34(4):511\u201322.","journal-title":"Echocardiography"},{"issue":"5","key":"10375_CR13","doi-asserted-by":"publisher","first-page":"66","DOI":"10.3390\/bioengineering8050066","volume":"8","author":"S Cutugno","year":"2021","unstructured":"Cutugno S, Ingrassia T, Nigrelli V, Pasta S. On the left ventricular remodeling of patients with stenotic aortic valve: a statistical shape analysis. Bioengineering. 2021;8(5):66.","journal-title":"Bioengineering"},{"issue":"4","key":"10375_CR14","first-page":"417","volume":"21","author":"AN Bhuva","year":"2020","unstructured":"Bhuva AN, Treibel TA, De Marvao A, Biffi C, Dawes TJ, Doumou G, Bai W, Patel K, Boubertakh R, Rueckert D. Sex and regional differences in myocardial plasticity in aortic stenosis are revealed by 3D model machine learning. Eur Heart J-Cardiovasc Imaging. 2020;21(4):417\u201327.","journal-title":"Eur Heart J-Cardiovasc Imaging"},{"issue":"4","key":"10375_CR15","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.echo.2017.02.009","volume":"30","author":"H Baumgartner","year":"2017","unstructured":"Baumgartner H, Hung J, Bermejo J, Chambers JB, Edvardsen T, Goldstein S, Lancellotti P, LeFevre M, Miller F Jr, Otto CM. Recommendations on the echocardiographic assessment of aortic valve stenosis: a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr. 2017;30(4):372\u201392.","journal-title":"J Am Soc Echocardiogr"},{"issue":"1","key":"10375_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2342-10-1","volume":"10","author":"E Heiberg","year":"2010","unstructured":"Heiberg E, Sj\u00f6gren J, Ugander M, Carlsson M, Engblom H, Arheden H. Design and validation of segment-freely available software for cardiovascular image analysis. BMC Med Imaging. 2010;10(1):1\u201313.","journal-title":"BMC Med Imaging"},{"issue":"7","key":"10375_CR17","doi-asserted-by":"publisher","first-page":"2715","DOI":"10.1088\/0031-9155\/60\/7\/2715","volume":"60","author":"YM Liew","year":"2015","unstructured":"Liew YM, McLaughlin R, Chan B, Aziz YA, Chee K, Ung N, Tan L, Lai K, Ng S, Lim E. Motion corrected LV quantification based on 3D modelling for improved functional assessment in cardiac MRI. Phys Med Biol. 2015;60(7):2715.","journal-title":"Phys Med Biol"},{"key":"10375_CR18","doi-asserted-by":"crossref","unstructured":"Ommen S, Nishimura R. A clinical approach to the assessment of left ventricular diastolic function by Doppler echocardiography: update 2003. Heart. 2003;89(suppl 3):iii18-iii23.","DOI":"10.1136\/heart.89.suppl_3.iii18"},{"issue":"4","key":"10375_CR19","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1002\/jmri.24239","volume":"39","author":"ML Chuang","year":"2014","unstructured":"Chuang ML, Gona P, Hautvast GL, Salton CJ, Breeuwer M, O\u2019Donnell CJ, Manning WJ. CMR reference values for left ventricular volumes, mass, and ejection fraction using computer-aided analysis: the Framingham Heart Study. J Magn Reson Imaging. 2014;39(4):895\u2013900.","journal-title":"J Magn Reson Imaging"},{"issue":"1","key":"10375_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12968-017-0327-9","volume":"19","author":"SE Petersen","year":"2017","unstructured":"Petersen SE, Aung N, Sanghvi MM, Zemrak F, Fung K, Paiva JM, Francis JM, Khanji MY, Lukaschuk E, Lee AM. Reference ranges for cardiac structure and function using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort. J Cardiovasc Magn Reson. 2017;19(1):1\u201319.","journal-title":"J Cardiovasc Magn Reson"},{"issue":"4","key":"10375_CR21","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1067\/mhj.2001.113394","volume":"141","author":"J Ortlepp","year":"2001","unstructured":"Ortlepp J, Breithardt O, Ohme F, Hanrath P, Hoffmann R. Lack of association among five genetic polymorphisms of the renin-angiotensin system and cardiac hypertrophy in patients with aortic stenosis. Am Heart J. 2001;141(4):671\u20136.","journal-title":"Am Heart J"},{"issue":"17","key":"10375_CR22","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1093\/eurheartj\/ehi290","volume":"26","author":"M Kupari","year":"2005","unstructured":"Kupari M, Turto H, Lommi J. Left ventricular hypertrophy in aortic valve stenosis: preventive or promotive of systolic dysfunction and heart failure? Eur Heart J. 2005;26(17):1790\u20136.","journal-title":"Eur Heart J"},{"issue":"4","key":"10375_CR23","doi-asserted-by":"publisher","first-page":"63","DOI":"10.3390\/medicina54040063","volume":"54","author":"B Gumauskien\u0117","year":"2018","unstructured":"Gumauskien\u0117 B, Krivickien\u0117 A, Jonkaitien\u0117 R, Va\u0161kelyt\u0117 JJ, Siudikas A, Ereminien\u0117 E. Impact of left ventricular diastolic dysfunction and biomarkers on pulmonary hypertension in patients with severe aortic stenosis. Medicina. 2018;54(4):63.","journal-title":"Medicina"},{"issue":"12","key":"10375_CR24","first-page":"2561","volume":"13","author":"H-J Lee","year":"2020","unstructured":"Lee H-J, Lee H, Kim SM, Park J-B, Kim EK, Chang S-A, Park E, Kim H-K, Lee W, Kim Y-J. Diffuse myocardial fibrosis and diastolic function in aortic stenosis. Cardiovasc Imaging. 2020;13(12):2561\u201372.","journal-title":"Cardiovasc Imaging"},{"issue":"3","key":"10375_CR25","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/S0894-7317(99)70136-7","volume":"12","author":"D-W Sohn","year":"1999","unstructured":"Sohn D-W, Kim Y-J, Kim H-C, Chun H-G, Park Y-B, Choi Y-S. Evaluation of left ventricular diastolic function when mitral E and A waves are completely fused: role of assessing mitral annulus velocity. J Am Soc Echocardiogr. 1999;12(3):203\u20138.","journal-title":"J Am Soc Echocardiogr"},{"issue":"4","key":"10375_CR26","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1177\/8756479319836781","volume":"35","author":"A Kossaify","year":"2019","unstructured":"Kossaify A, Nasr M. Diastolic dysfunction and the new recommendations for echocardiographic assessment of left ventricular diastolic function: summary of guidelines and novelties in diagnosis and grading. J Diagn Med Sonogr. 2019;35(4):317\u201325.","journal-title":"J Diagn Med Sonogr"}],"container-title":["Journal of Cardiovascular Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12265-023-10375-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12265-023-10375-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12265-023-10375-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T16:18:49Z","timestamp":1698682729000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12265-023-10375-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,6]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10375"],"URL":"https:\/\/doi.org\/10.1007\/s12265-023-10375-9","relation":{},"ISSN":["1937-5387","1937-5395"],"issn-type":[{"value":"1937-5387","type":"print"},{"value":"1937-5395","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,6]]},"assertion":[{"value":"27 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 April 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the University Malaya Medical Centre Medical Research Ethics Committee (201866\u20136364).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}