{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:42:34Z","timestamp":1791247354577,"version":"4.1.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch. Pharm. Res."],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1007\/s12272-008-1123-8","type":"journal-article","created":{"date-parts":[[2008,3,25]],"date-time":"2008-03-25T11:02:29Z","timestamp":1206442949000},"page":"75-82","source":"Crossref","is-referenced-by-count":33,"title":["Identification of estrogenic and antiestrogenic activities of respirable diesel exhaust particles by bioassay-directed fractionation"],"prefix":"10.1007","volume":"31","author":[{"given":"Seung Min","family":"Oh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Taek","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu Hyuck","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,3,26]]},"reference":[{"key":"1123_CR1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0300-483X(99)00018-9","volume":"133","author":"K. F. Arcaro","year":"1999","unstructured":"Arcaro, K. F., O\u2019Keefe, P. W., Yang, Y., Clayton, W., and Gierthy, J. F., Antiestrogenicity of environmental polycyclic aromatic hydrocarbons in human breast cancer cells. Toxicology, 133, 155\u2013127 (1999).","journal-title":"Toxicology"},{"key":"1123_CR2","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1021\/es00177a009","volume":"22","author":"J. M. Bayona","year":"1988","unstructured":"Bayona, J. M., Markides, K. E., and Lee, M. L., Characterization of polar polycyclic aromatic compounds in a heavy-duty diesel exhaust particulate by capillary column gas chromatography and high-resolution mass spectrometry. Environ. Sci. Technol., 22, 1440\u20131447 (1988).","journal-title":"Environ. Sci. Technol."},{"key":"1123_CR3","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1093\/toxsci\/57.2.302","volume":"57","author":"D. L. Buchanan","year":"2000","unstructured":"Buchanan, D. L., Sato, T., Peterson, R. E., and Cooke, P. S., Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse uterus: critical role of the aryl hydrocarbon receptor in stromal tissue, Toxicological Sciences, 57, 302\u2013311 (2000).","journal-title":"Toxicological Sciences"},{"key":"1123_CR4","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1093\/carcin\/13.12.2233","volume":"13","author":"K. Chaloupka","year":"1992","unstructured":"Chaloupka, K., Krishnan, V., and Safe, S., Polynuclear aromatic hydrocarbon carcinogens as antiestrogens in MCF-7 human breast cancer cells: Role of the Ah receptor. Carcinogenesis, 13, 2233\u20132239 (1992).","journal-title":"Carcinogenesis"},{"key":"1123_CR5","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1093\/toxsci\/55.2.320","volume":"55","author":"G. D. Charles","year":"2000","unstructured":"Charles, G. D., Bartels, M. J., Zacharewski, T. R., Gollapudi, B. B., Freshour, E. W., and Carney, E. W., Activity of benzo(a)pyrene and its hydroxylated metabolites in an estrogen receptor-a reporter gene assay. Toxicological Sciences, 55, 320\u2013326 (2000).","journal-title":"Toxicological Sciences"},{"key":"1123_CR6","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/381379a0","volume":"381","author":"C. Clunies-Ross","year":"1996","unstructured":"Clunies-Ross, C., Stanmore, B. R., and Millar, G. J., Dioxins in diesel exhaust, Nature (London), 381, 379 (1996).","journal-title":"Nature (London)"},{"key":"1123_CR7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0378-4274(01)00344-7","volume":"121","author":"K. C. Fertuck","year":"2001","unstructured":"Fertuck, K. C., Kumar, S., Sikka, H. C., Matthews, J. B., and Zacharewski, T. R., Interaction of PAH-related compounds with the a and b isoforms of the estrogen receptor. Toxicology letters, 121, 167\u2013177 (2001).","journal-title":"Toxicology letters"},{"key":"1123_CR8","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1095\/biolreprod.103.024810","volume":"70","author":"C. Furuta","year":"2004","unstructured":"Furuta, C., Suzuki, A. K., Taneda, S., Kamata, K., Hayashi, H., Mori, Y., Li, C., Watanabe, G., and Taya, K., Estrogenic activities of nitrophenols in diesel exhaust particles. Biology of Reproduction, 70, 1527\u20131533 (2004).","journal-title":"Biology of Reproduction"},{"key":"1123_CR9","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1080\/08958370050198539","volume":"12","author":"L. Gill","year":"2000","unstructured":"Gill, L., King, L., and Adonis, M., Trends of polycyclic aromatic hydrocarbon levels and mutagenicity in Santiago\u2019s inhalable airborne particles in the period, 1992\u20131996. Inhalation Toxicology, 12, 1185\u20131204 (2000).","journal-title":"Inhalation Toxicology"},{"key":"1123_CR10","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.taap.2003.12.003","volume":"196","author":"J. M. Gozgit","year":"2004","unstructured":"Gozgit, J. M., Nestor, K. M., Fasco, M. J., Pentecost, B. T., and Arcaro, K. F., Differential action of polycyclic aromatic hydrocarbons on endogenous estrogen-responsive genes and on a transfected estrogen-responsive reporter in MCF-7 cells. Toxicology and Applied Pharmacology, 196, 58\u201367 (2004).","journal-title":"Toxicology and Applied Pharmacology"},{"key":"1123_CR11","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1600-0773.1991.tb01327.x","volume":"69","author":"A. Hanberg","year":"1991","unstructured":"Hanberg, A., Strahlberg, M., Georgellies, A., de Wit, C., and Ahlborg, U. G., Swedish dioxin survey: induction. Pharmacol Toxicol., 69, 442\u2013449 (1991).","journal-title":"Pharmacol Toxicol."},{"key":"1123_CR12","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0887-2333(01)00046-7","volume":"15","author":"Y. Hashimoto","year":"2001","unstructured":"Hashimoto, Y., Moriguchi, Y., Oshima, H., Kawaguchi, M., Miyazaki, K., and Nakamura, M., Measurement of estrogenic activity of chemicals for the development of new dental polymers. Toxicology In Vitro, 15, 421\u2013425 (2001).","journal-title":"Toxicology In Vitro"},{"key":"1123_CR13","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1021\/es0261269","volume":"37","author":"K. J. Higgins","year":"2003","unstructured":"Higgins, K. J., Jung, H., Kittelson, D. B., Roberts, J. T., and Zachariah, M. R., Kinetics of diesel nanoparticle oxidation, Environ. Sci. Technol., 37, 179\u2013190 (2003).","journal-title":"Environ. Sci. Technol."},{"key":"1123_CR14","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1021\/es025868z","volume":"37","author":"S. B. Kwon","year":"2003","unstructured":"Kwon, S. B., Lee, K. W., Saito, K., Shinozaki, O., and Seto, T., Size-dependent volatility of diesel nanoparticles: Chassis dynamometer experiments. Environ. Sci. Technol., 37, 1794\u20131802 (2003).","journal-title":"Environ. Sci. Technol."},{"key":"1123_CR15","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/03067319008032068","volume":"39","author":"J. Lewtas","year":"1990","unstructured":"Lewtas, J., Chuang, J., Nishioka, M., and Peterson B., Bioassay-directed fractionation of the organic extract of SRM1649 urban air particulate matter. Int. J. Environ. Anal. Chem., 39, 245\u2013256 (1990).","journal-title":"Int. J. Environ. Anal. Chem."},{"key":"1123_CR16","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1677\/joe.1.06628","volume":"189","author":"C. Li","year":"2006","unstructured":"Li, C., Takahashi, S., Taneda, S., Furuta, C., Watanabe, G., Suzuki, A. K., and Taya, K., Impairment of testicular function in adult male Japanese quail (Coturnix japonica) after a single administration of 3-methyl-4-nitrophenol in diesel exhaust particles. Journal of Endocrinology, 189, 555\u2013564 (2006).","journal-title":"Journal of Endocrinology"},{"key":"1123_CR17","first-page":"2736","volume":"20","author":"M. Machala","year":"2001","unstructured":"Machala, M., Ciganek, M., L., Bl\u00e1ha, L., Minksov\u00e1, K., and Vondr\u00e1\u00e8k, J., Aryl hydrocarbon receptor-mediated and estrogenic activities of oxygenated polycyclic aromatic hydrocarbons and azaarenes originally identified in extracts of river sediments. Environmental Toxicology and Chemistry, 20, 2736\u20132743 (2001).","journal-title":"Environmental Toxicology and Chemistry"},{"key":"1123_CR18","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1210\/en.2002-221054","volume":"144","author":"M. B. Martin","year":"2003","unstructured":"Martin, M. B., Reiter, R., Pham, T., Avellanet, Y. R., Camara, J., Lahm, M., Pentecost, E., Pratap, K., Gilmore, B. A., Divekar, S., Dagata, R. S., Bull, J. L., and Stoica, A., Estrogen-like activity of metals in MCF-7 breast cancer cells. Endocrinology, 144, 2425\u20132436 (2003).","journal-title":"Endocrinology"},{"key":"1123_CR19","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1006\/enrs.1998.3870","volume":"79","author":"M. D. Meek","year":"1998","unstructured":"Meek, M. D., Ah receptor and estrogen receptor-dependent modulation of gene expression by extracts of diesel exhaust particles. Environ. Res. Section A, 79, 114\u2013121 (1998).","journal-title":"Environ. Res. Section A"},{"key":"1123_CR20","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1248\/bpb.25.145","volume":"25","author":"Y. Mori","year":"2002","unstructured":"Mori, Y., Taneda, S., Hayashi, H., Sakushima, A., Kamata, K., Suzuki, A.K., Yoshino, S., Sakata, M., Sagai, M., and Seki, K., Estrogenic activities of chemicals in diesel exhaust particles. Bio. Pharm. Bull., 25, 145\u2013146 (2002).","journal-title":"Bio. Pharm. Bull."},{"key":"1123_CR21","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF02986390","volume":"5","author":"J. M. Navas","year":"1998","unstructured":"Navas, J. M. and Segner, H., Antiestrogenic activity of anthropogenic and natural chemicals. Environ. Sci. Pollut. Res., 5, 75\u201382 (1998).","journal-title":"Environ. Sci. Pollut. Res."},{"key":"1123_CR22","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1002\/bmc.861","volume":"21","author":"K. Noguchi","year":"2007","unstructured":"Noguchi, K., Toriba, A., Chung, S. W., Kizu, R., and Hayakawa, K., Identification of estroenic\/anti-estrogenic compounds in diesel exhaust particulate extract. Biomedial Chromatography, 21, 1135\u20131142 (2007).","journal-title":"Biomedial Chromatography"},{"key":"1123_CR23","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.tiv.2004.04.004","volume":"18","author":"G. N. Oenga","year":"2004","unstructured":"Oenga, G. N., Spink, D. C., and Carpenter, D. O., TCDD and PCBs inhibit breast cancer cell proliferation in vitro. Toxicology In Vitro, 18, 811\u2013819 (2004).","journal-title":"Toxicology In Vitro"},{"key":"1123_CR24","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.toxlet.2005.09.008","volume":"161","author":"S. M. Oh","year":"2006","unstructured":"Oh, S. M. and Chung, K. H., Identification of mammalian cell genotoxins in respirable diesel exhaust particles by bioassay-directed chemical analysis. Toxicology Letters, 161, 226\u2013235 (2006).","journal-title":"Toxicology Letters"},{"key":"1123_CR25","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1289\/ehp.96104298","volume":"104","author":"N. Olea","year":"1996","unstructured":"Olea, N., Pulgar, R., Perez, P., Olea-Serrano, F., Rivas, A., Novillo-Fertrell, A., Pedraza, V., Soto, A. M., and Sonnenschein, C., Estrogenicity of resin-based composities and sealants used in dentistry. Environ. Health Perspect., 104, 298\u2013305 (1996).","journal-title":"Environ. Health Perspect."},{"key":"1123_CR26","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1289\/ehp.98106167","volume":"106","author":"P. Perez","year":"1998","unstructured":"Perez, P., Pulgar, R., Olea-Serrano, F., Villalobos, M., Rivas, A., Metzler, M., Pedraza, V., and Olea, N., The estrogenicity of bisphenol A-related diphenylalkanes with various substituents at the central carbon and the hydroxyl group. Environ. Health Perspect., 106, 167\u2013174 (1998).","journal-title":"Environ. Health Perspect."},{"key":"1123_CR27","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/toxsci\/kfi040","volume":"83","author":"M. Pl\u00ed\u0161kov\u00e1","year":"2005","unstructured":"Pl\u00ed\u0161kov\u00e1, M., Vondr\u00e1\u00e8ek, J., Vojt\u00ec\u0161ek, B., Kozub\u00edk, A., and Machala, M., Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events. Toxicological Sciences, 83, 246\u2013256 (2005).","journal-title":"Toxicological Sciences"},{"key":"1123_CR28","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF02986921","volume":"1","author":"S. Safe","year":"1994","unstructured":"Safe, S., Dietary and environmental estrogens and antiestrogens and their possible role in human disease. Environ. Sci. Pollut. Res., 1, 29\u201333 (1994).","journal-title":"Environ. Sci. Pollut. Res."},{"key":"1123_CR29","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0163-7258(95)00017-B","volume":"67","author":"S. Safe","year":"1995","unstructured":"Safe, S., Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds, Pharmacol. Ther., 67, 247\u2013281 (1995).","journal-title":"Pharmacol. Ther."},{"key":"1123_CR30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1146\/annurev.pharmtox.38.1.121","volume":"38","author":"S. Safe","year":"1998","unstructured":"Safe, S., Interactions between hormone and chemicals in breast cancer. Annu. Rev. Pharmacol. Toxicol., 38, 121\u2013158 (1998).","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"1123_CR31","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1600-0773.1991.tb01321.x","volume":"69","author":"S. Safe","year":"1991","unstructured":"Safe, S., Astroff, B., Harris, M., Zacharewski, T., Dickerson, R., Romkes, M., and Biegel, L., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antioestrogens: characterization and mechanisms of action. Pharmacol. Toxicol., 69, 400\u2013409 (1991).","journal-title":"Pharmacol. Toxicol."},{"key":"1123_CR32","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1021\/tx034036r","volume":"16","author":"S. Safe","year":"2003","unstructured":"Safe, S. and W\u00f6rmke, M., Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action. Chem. Res. Toxicol., 16, 807\u2013816 (2003).","journal-title":"Chem. Res. Toxicol."},{"key":"1123_CR33","first-page":"1060A","volume":"58","author":"D. Schuetzle","year":"1986","unstructured":"Schuetzle, D. and Lewtas, J., Bioassay-directed chemical analysis in environmental research. Anal. Chem., 58, 1060A\u20131075A (1986).","journal-title":"Anal. Chem."},{"key":"1123_CR34","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0300-483X(01)00516-9","volume":"170","author":"S. Taneda","year":"2002","unstructured":"Taneda, S., Hayashi, H., Sakushima, A., Seki, K., Suzuki, A.K., Kamata, K., Sakata, M., Yoshino, S., Sagai, M., and Mori, Y., Estrogenic and anti-estrogenic activities of two types of diesel exhaust particles. Toxicology, 170, 153\u2013161 (2002).","journal-title":"Toxicology"},{"key":"1123_CR35","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1248\/bpb.27.835","volume":"27","author":"S. Taneda","year":"2004","unstructured":"Taneda, S., Mori, Y., Kamata, K., Hayashi, H., Furuta, C., Li, C., Seki, K., Sakushima, A., Yoshino, S., Yamaki, K., Watanabe, G., Taya, K., and Suzuki, A. K., Estrogenic and anti-estrogenic activity of nitrophenols in diesel exhaust particles (DEP). Biol. Pharm. Bull., 27, 835\u2013837 (2004).","journal-title":"Biol. Pharm. Bull."},{"key":"1123_CR36","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1383-5718(98)00127-2","volume":"419","author":"J. Topinka","year":"1998","unstructured":"Topinka, J., Schwarz, L. R., Kiefer, F., Wiebel, F. J., Gajdo\u0161, O., Vidov\u00e1, P., Dobi\u00e1\u0161, L., Fried, M., \u0160r\u00e1m, R.J., and Wolff, T., DNA adduct formation in mammalian cell cultures by polycyclic aromatic hydrocarbons (PAH) and nitro-PAH in coke oven emission extract. Mutation Research, 419, 91\u2013105 (1998).","journal-title":"Mutation Research"},{"key":"1123_CR37","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1006\/bbrc.1996.1764","volume":"229","author":"D. Q. Tran","year":"1996","unstructured":"Tran, D. Q., Ide, C. F., McLachlan, J. A., and Arnold, S. F., The anti-estrogenic activity of selected polynuclear aromatic hydrocarbons in yeast expressing human estrogen receptor. Biochemical and Biophysical Research Communications, 229, 102\u2013108 (1996).","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"1123_CR38","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/15287390151126441","volume":"A63","author":"N. Tsukue","year":"2001","unstructured":"Tsukue, N., Toda, N., Tsubone, H., Sagai, M., Jin, W. Z., Watanabe, G., Taya, K., Birumachi, J., and Suzuki, A. K., Diesel exhaust (DE) affects the regulation of testicular function in male Fishcher 344 rats. J. Toxicol Environ Health, A63, 115\u2013126 (2001).","journal-title":"J. Toxicol Environ Health"},{"key":"1123_CR39","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1080\/08958370290084548","volume":"14","author":"N. Tsukue","year":"2002","unstructured":"Tsukue, N., Tsubone, H., and Suzuki, A. K., Diesel exhaust affects the abnormal delivery in pregnant mice and the growth of their young. Inhal. Toxicol., 14, 635\u2013651 (2002).","journal-title":"Inhal. Toxicol."},{"key":"1123_CR40","unstructured":"U.S. Environmental Protection Agency (EPA), 2002. Health assessment document for diesel engine exhaust, Prepared by the National Center for Environmental Assessment, Washington, DC, for the Office of Transportation and Air Quality; EPA\/600\/8-90\/057F."},{"key":"1123_CR41","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/toxsci\/70.2.193","volume":"70","author":"J. Vondr\u00e1\u00e8ek","year":"2002","unstructured":"Vondr\u00e1\u00e8ek, J., Kozub\u00edk, A., and Machala, M., Modulation of estrogen receptor-dependent reporter construct activation and G0\/G1-S-phase transition by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells. Toxicological Sciences, 70, 193\u2013201 (2002).","journal-title":"Toxicological Sciences"},{"key":"1123_CR42","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1006\/abbi.1998.0782","volume":"356","author":"W. L. Wang","year":"1998","unstructured":"Wang, W. L., Smith, R., and Safe, S., Aryl hydrocarbon receptor-mediated antiestrogenicity in MCF-7 cells: Modulation of hormone-induced cell cycle enzymes. Arch. Biochem. Biophys., 356, 239\u2013248 (1998).","journal-title":"Arch. Biochem. Biophys."},{"key":"1123_CR43","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1289\/ehp.99107539","volume":"107","author":"N. Watanabe","year":"1999","unstructured":"Watanabe, N. and Oonuke, Y., Inhalation of diesel engine exhaust affects spermatogenesis in growing male rats. Environ. Health Perspect., 107, 539\u2013544 (1999).","journal-title":"Environ. Health Perspect."},{"key":"1123_CR44","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1046\/j.1365-2605.1999.00185.x","volume":"22","author":"S. Yoshida","year":"1999","unstructured":"Yoshida, S., Sagai, M., Oshio, S., Umeda, T., Ihara, T., Sugamata, M., Sugawara, I., and Takada, K., Exposure to diesel exhaust affects the male reproductive system of mice. Int. J. Androl., 22, 307\u2013315 (1999).","journal-title":"Int. J. Androl."}],"container-title":["Archives of Pharmacal Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12272-008-1123-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12272-008-1123-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12272-008-1123-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T16:22:37Z","timestamp":1559578957000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12272-008-1123-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["1123"],"URL":"https:\/\/doi.org\/10.1007\/s12272-008-1123-8","relation":{},"ISSN":["0253-6269","1976-3786"],"issn-type":[{"value":"0253-6269","type":"print"},{"value":"1976-3786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}