{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T13:38:32Z","timestamp":1712065112648},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2013,7,4]],"date-time":"2013-07-04T00:00:00Z","timestamp":1372896000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch. Pharm. Res."],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1007\/s12272-013-0166-7","type":"journal-article","created":{"date-parts":[[2013,7,2]],"date-time":"2013-07-02T22:34:15Z","timestamp":1372804455000},"page":"1270-1278","source":"Crossref","is-referenced-by-count":4,"title":["Positive inotropic activity induced by a dehydroisoandrosterone derivative in isolated rat heart model"],"prefix":"10.1007","volume":"36","author":[{"given":"L.","family":"Figueroa-Valverde","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"D\u00edaz-Cedillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Garc\u00eda-Cervera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Pool G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"L\u00f3pez-Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Rosas-Nexticapa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Martinez-Camacho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,7,4]]},"reference":[{"key":"166_CR1","first-page":"187","volume":"29","author":"T Akera","year":"1977","unstructured":"Akera, T., and M. Brody. 1977. The role of Na+, K+-ATPase in the inotropic action of digitalis. Pharmacological Reviews 29: 187\u2013220.","journal-title":"Pharmacological Reviews"},{"issue":"4","key":"166_CR2","first-page":"208","volume":"9","author":"K Bayne","year":"1996","unstructured":"Bayne, K. 1996. Revised guide for the care and use of laboratory animals available. American Physiological Society Physiology 9(4): 208\u2013211.","journal-title":"American Physiological Society Physiology"},{"key":"166_CR3","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1002\/cpt1975174400","volume":"17","author":"C Bengtsson","year":"1975","unstructured":"Bengtsson, C., G. Johnsson, and C. Reg\u00e5rdh. 1975. Plasma levels and effects of metoprolol on blood pressure and heart rate in hypertensive patients after an acute dose and between two doses during long-term treatment. Clinical Pharmacology and Therapeutics 17: 400\u2013408.","journal-title":"Clinical Pharmacology and Therapeutics"},{"key":"166_CR4","first-page":"85","volume":"73","author":"JR Blinks","year":"1986","unstructured":"Blinks, J.R., and M. Endoh. 1986. Modification of myofibrillar responsiveness to Ca++ as an inotropic mechanism. Circulation 73: 85\u201398.","journal-title":"Circulation"},{"key":"166_CR5","doi-asserted-by":"crossref","first-page":"13798","DOI":"10.1021\/ja0768136","volume":"29","author":"JW Bode","year":"2007","unstructured":"Bode, J.W., and S. Sohn. 2007. N-Heterocyclic carbene-catalyzed redox amidations of a-functionalized aldehydes with amines. Journal of the American Chemical Society 29: 13798\u201313799.","journal-title":"Journal of the American Chemical Society"},{"issue":"IV","key":"166_CR6","first-page":"14","volume":"102","author":"E Braunwald","year":"2000","unstructured":"Braunwald, E., and M. Bristow. 2000. Congestive heart failure: Fifty years of progress. Circulation 102(IV): 14\u201323.","journal-title":"Circulation"},{"key":"166_CR7","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1097\/00005344-199905000-00003","volume":"33","author":"G Ceballos","year":"1999","unstructured":"Ceballos, G., L. Figueroa, I. Rubio, A. Garc\u00eda, A. Mart\u00ednez, and R. Ya\u00f1ez. 1999. Acute and nongenomic effects of testosterone on isolated and perfused rat heart. Journal of Cardiovascular Pharmacology 33: 691\u2013697.","journal-title":"Journal of Cardiovascular Pharmacology"},{"issue":"8","key":"166_CR8","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1210\/en.2005-0263","volume":"146","author":"I Charalampopoulos","year":"2005","unstructured":"Charalampopoulos, I., E. Dermitzaki, L. Vardouli, C. Tsatsanis, C. Stournaras, A. Margioris, and A. Gravanis. 2005. Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization. Endocrinol 146(8): 3309\u20133318.","journal-title":"Endocrinol"},{"issue":"3","key":"166_CR9","first-page":"215","volume":"5","author":"AJ Clark","year":"1914","unstructured":"Clark, A.J. 1914. The mode of action of strophanthidin upon cardiac tissue. Journal of Pharmacology and Experimental Therapeutics 5(3): 215\u2013234.","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"issue":"17","key":"166_CR10","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.1021\/jm030830y","volume":"46","author":"S Munari De","year":"2003","unstructured":"De Munari, S., A. Cerri, M. Gobbini, N. Almirante, L. Banfi, and G. Carzana. 2003. Structure-based design and synthesis of novel potent na+, k+-atpase inhibitors derived from a 5\u03b1, 14\u03b1-androstane scaffold as positive inotropic compounds. Journal of Medicinal Chemistry 46(17): 3644\u20133654.","journal-title":"Journal of Medicinal Chemistry"},{"key":"166_CR11","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1165\/rcmb.2003-0186OC","volume":"29","author":"N DeSilva","year":"2003","unstructured":"DeSilva, N. 2003. Interactions of surfactant protein D with fatty acids. American Journal of Respiratory Cell and Molecular Biology 29: 757\u2013770.","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"key":"166_CR12","first-page":"117","volume":"73","author":"M Endoh","year":"1986","unstructured":"Endoh, M., T. Yanagisawa, N. Taira, and J. Blinks. 1986. Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle. Circulation 73: 117\u2013133.","journal-title":"Circulation"},{"key":"166_CR13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01735205","volume":"66","author":"E Erdmann","year":"1988","unstructured":"Erdmann, E. 1988. The effectiveness of inotropic agents in isolated cardiac preparations from the human heart. Klin Wochenschr 66: 1\u20136.","journal-title":"Klin Wochenschr"},{"issue":"4","key":"166_CR14","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/0735-1097(93)90441-3","volume":"22","author":"A Feldman","year":"1993","unstructured":"Feldman, A. 1993. Classification of positive inotropic agents. Journal of the American College of Cardiology 22(4): 1223\u20131227.","journal-title":"Journal of the American College of Cardiology"},{"issue":"7","key":"166_CR15","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0039-128X(02)00011-9","volume":"67","author":"L Figueroa-Valverde","year":"2002","unstructured":"Figueroa-Valverde, L., H. Luna, C. Castillo-henkel, Mu\u00f1oz-Garc\u00eda, and G. Ceballos-Reyes. 2002. Synthesis and evaluation of the cardiovascular effects of two, membrane impermeant, macromolecular complexes of dextran-testosterone. Steroids 67(7): 611\u2013619.","journal-title":"Steroids"},{"issue":"4","key":"166_CR16","doi-asserted-by":"crossref","first-page":"625","DOI":"10.7705\/biomedica.v29i4.140","volume":"29","author":"L Figueroa","year":"2009","unstructured":"Figueroa, L., F. D\u00edaz, A. Camacho, E. D\u00edaz, and R. Marvin. 2009. Actividad inducida por androsterona y hemisuccinato de androsterona sobre la presi\u00f3n de perfusi\u00f3n y la resistencia vascular. Biom\u00e9dica 29(4): 625\u2013634.","journal-title":"Biom\u00e9dica"},{"key":"166_CR17","first-page":"234","volume":"3","author":"L Figueroa-Valverde","year":"2009","unstructured":"Figueroa-Valverde, L., F. D\u00edaz-Cedillo, E. Diaz-Ku, and A. Camacho-Luis. 2009. Effect induced by hemisuccinate of pregnenolone on perfusion pressure and vascular resistance in isolated rat heart. African Journal of Pharmacy and Pharmacology 3: 234\u2013241.","journal-title":"African Journal of Pharmacy and Pharmacology"},{"key":"166_CR18","first-page":"170","volume":"4","author":"L Figueroa Valverde","year":"2010","unstructured":"Figueroa Valverde, L., G. Ceballos-Reyes, F. D\u00edaz-Cedillo, A. Camacho-Luis, M. L\u00f3pez-Ramos, and G. Maldonado-Velazquez. 2010. Biological activity of progesterone-dihydropyridimidine derivative on perfusion pressure and coronary resistance in isolated rat heart. African Journal of Pharmacy and Pharmacology 4: 170\u2013177.","journal-title":"African Journal of Pharmacy and Pharmacology"},{"issue":"1","key":"166_CR19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.5507\/bp.2011.018","volume":"155","author":"L Figueroa-Valverde","year":"2011","unstructured":"Figueroa-Valverde, L., F. D\u00edaz-Cedillo, M. L\u00f3pez-Ramos, and E. Garc\u00eda-Cervera. 2011a. Changes induced by estradiol-ethylenediamine derivative on perfusion pressure and coronary resistance in isolated rat heart: L-type calcium channel. Biomedical Papers 155(1): 27\u201332.","journal-title":"Biomedical Papers"},{"issue":"4","key":"166_CR20","first-page":"1599","volume":"23","author":"L Figueroa-Valverde","year":"2011","unstructured":"Figueroa-Valverde, L., F. D\u00edaz-Cedillo, M. L\u00f3pez-Ramos, E. Garc\u00eda-Cervera, and K. Quijano-Ascencio. 2011b. Synthesis of a new inotropic steroid derivative and its relationship with log P, \u03c0, Rm, Vm, Pc. Asian Journal of Chemistry 23(4): 1599\u20131604.","journal-title":"Asian Journal of Chemistry"},{"key":"166_CR21","doi-asserted-by":"crossref","first-page":"232","DOI":"10.7705\/biomedica.v31i2.310","volume":"31","author":"L Figueroa-Valverde","year":"2011","unstructured":"Figueroa-Valverde, L., F. D\u00edaz-Cedillo, M. L\u00f3pez-Ramos, E. Garc\u00eda-Cervera, and K. Quijano-Ascencio. 2011c. Inotropic activity induced by carbamazepine-alkyne derivative in an isolated heart model and perfused to constant flow. Biomedica 31: 232\u2013241.","journal-title":"Biomedica"},{"issue":"5","key":"166_CR22","first-page":"2173","volume":"24","author":"L Figueroa-Valverde","year":"2012","unstructured":"Figueroa-Valverde, L., F. D\u00edaz-Cedillo, and E. Garc\u00eda-Cervera. 2012. Design and synthesis of two brucine derivatives and evaluation of its antibacterial activity against Escherichia coli and Salmonella typhi. Asian Journal of Chemistry 24(5): 2173\u20132176.","journal-title":"Asian Journal of Chemistry"},{"issue":"23","key":"166_CR23","doi-asserted-by":"crossref","first-page":"3821","DOI":"10.1021\/jm0109208","volume":"44","author":"M Gobbini","year":"2001","unstructured":"Gobbini, M., P. Barassi, A. Cerri, S. De Munari, G. Fedrizzi, and M. Santagostino. 2001. 17 alpha-O-(aminoalkyl) oxime derivatives of 3 beta, 14 beta-dihydroxy-5 beta-androstane and 3 beta-hydroxy-14-oxoseco-D-5 beta-androstane as inhibitors of Na(+), K(+)-ATPase at the digitalis receptor. Journal of Medicinal Chemistry 44(23): 3821\u20133830.","journal-title":"Journal of Medicinal Chemistry"},{"key":"166_CR24","first-page":"747","volume":"201","author":"R Graham","year":"1977","unstructured":"Graham, R., H. Oates, L. Stoker, and G. Stokes. 1977. Alpha blocking action of the antihypertensive agent, prazosin. Journal of Pharmacology and Experimental Therapeutics 201: 747\u2013752.","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"166_CR25","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1021\/jo01127a025","volume":"20","author":"R Hauser","year":"1955","unstructured":"Hauser, R., and D. Hoffenberg. 1955. Conversion of nitriles to amides and acids by means of boron fluoride. Journal of Organic Chemistry 20: 1448\u20131453.","journal-title":"Journal of Organic Chemistry"},{"key":"166_CR26","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/0002-9149(80)90366-5","volume":"46","author":"PD Henry","year":"1980","unstructured":"Henry, P.D. 1980. Comparative pharmacology of calcium antagonists: nifedipine, verapamil and diltiazem. American Journal of Cardiology 46: 1047\u20131058.","journal-title":"American Journal of Cardiology"},{"key":"166_CR27","first-page":"769","volume":"67","author":"C Hocht","year":"1999","unstructured":"Hocht, C., L. Opezzo, S. Gorzalczany, G. Bramuglia, and C. Tiara. 1999. Una aproximaci\u00f3n cin\u00e9tica y din\u00e1mica de metildopa en ratas con coartaci\u00f3n a\u00f3rtica mediante microdi\u00e1lisis. Review of Argent Cardiology 67: 769\u2013773.","journal-title":"Review of Argent Cardiology"},{"issue":"3","key":"166_CR28","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/01.fjc.0000175434.64412.9d","volume":"46","author":"S Hutchison","year":"2005","unstructured":"Hutchison, S., A. Browne, E. Ko, T. Chou, C. Zellner, and P. Komesaroff. 2005. Dehydroepiandrosterone sulfate induces acute vasodilation of porcine coronary arteries in vitro and in vivo. Journal of Cardiovascular Pharmacology 46(3): 325\u2013332.","journal-title":"Journal of Cardiovascular Pharmacology"},{"key":"166_CR29","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/00000539-200001000-00003","volume":"90","author":"J Kersten","year":"2000","unstructured":"Kersten, J., M. Montgomery, S. Pagel, and D. Warltier. 2000. Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of KATP channels. Anesthesia and Analgesia 90: 5\u201311.","journal-title":"Anesthesia and Analgesia"},{"key":"166_CR30","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1113\/jphysiol.1976.sp011622","volume":"263","author":"W Lederer","year":"1976","unstructured":"Lederer, W., and R. Tsien. 1976. Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in purkinjefibres. Journal of Phsiology 263: 73\u2013100.","journal-title":"Journal of Phsiology"},{"key":"166_CR31","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1021\/op970206t","volume":"1","author":"D Levin","year":"1997","unstructured":"Levin, D. 1997. Potential toxicological concerns associated with carboxylic acid chlorination and other reactions. Organic Process Research & Development 1: 182.","journal-title":"Organic Process Research & Development"},{"issue":"11","key":"166_CR32","first-page":"1301","volume":"42","author":"J Maixten","year":"1992","unstructured":"Maixten, J., I. Bertrand, G. leliever, and S. Fernand. 1992. Efficacy and safety of the novel Na+, K+-ATPase inhibitor 20R 14\u03b2-amino 3\u03b2-rhamnosyl 5\u03b2-pregnan 20\u03b2-ol in a dog model of heart failure. Arzneimittel-Forschung 42(11): 1301\u20131305.","journal-title":"Arzneimittel-Forschung"},{"key":"166_CR33","first-page":"143","volume":"ix","author":"A Medvedeva","year":"2001","unstructured":"Medvedeva, A., M. Andreev, L. Safronova, and G. Sarapulova. 2001. Preparation of 3-(trimethylsilanyl)propynoic acid N-(hydroxyalkyl)amides. Arkivoc ix: 143\u2013149.","journal-title":"Arkivoc"},{"issue":"7","key":"166_CR34","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/sj.bjp.0706673","volume":"147","author":"C Pignier","year":"2006","unstructured":"Pignier, C., M. Keller, B. Vi\u00e9, B. Vacher, M. Santelli, E. Niggli, M. Egger, and B. Le Grand. 2006. A novel steroid-like compound F90927 exerting positive-inotropic effects in cardiac muscle. British Journal of Pharmacology 147(7): 772\u2013782.","journal-title":"British Journal of Pharmacology"},{"issue":"9","key":"166_CR35","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1093\/oxfordjournals.eurheartj.a059571","volume":"10","author":"L Pierard","year":"1989","unstructured":"Pierard, L., C. Berthe, A. Albert, J. Carlier, and H. Kulbertus. 1989. Haemodynamic alterations during ischaemia induced by dobutamine stress testing. European Heart Journal 10(9): 783\u2013790.","journal-title":"European Heart Journal"},{"key":"166_CR36","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1021\/ol006020n","volume":"2","author":"S Rannard","year":"2000","unstructured":"Rannard, S., and N. Davis. 2000. The selective reaction of primary amines with carbonyl imidazole containing compounds: Selective amide and carbamate synthesis. Organic Letters 2: 2117\u20132120.","journal-title":"Organic Letters"},{"issue":"7","key":"166_CR37","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1016\/S0735-1097(00)00613-6","volume":"35","author":"D Silverberg","year":"2000","unstructured":"Silverberg, D., D. Wexler, M. Blum, G. Keren, D. Sheps, E. Leibovitch, and D. Brosh. 2000. The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class, and markedly reduces hospitalizations. Journal of the American College of Cardiology 35(7): 1737\u20131744.","journal-title":"Journal of the American College of Cardiology"},{"key":"166_CR38","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0303-7207(86)90132-2","volume":"44","author":"J Simard","year":"1986","unstructured":"Simard, J., I. Luthy, J. Guay, A. B\u00e9langer, and F. Labrie. 1986. Characteristics of interaction of the antiandrogen flutamide with the androgen receptor in various target tissues. Molecular and Cellular Endocrinology 44: 261\u2013270.","journal-title":"Molecular and Cellular Endocrinology"},{"key":"166_CR39","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/0002-9343(75)90118-7","volume":"58","author":"TW Smith","year":"1975","unstructured":"Smith, T.W. 1975. Digitalis toxicity: Epidemiology and clinical use of serum concentration measurements. American Journal of Medicine 58: 470\u2013476.","journal-title":"American Journal of Medicine"},{"issue":"4","key":"166_CR40","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1210\/me.11.4.450","volume":"11","author":"J Tan","year":"1997","unstructured":"Tan, J., Y. Sharief, K. Hamil, C. Gregory, D. Zang, and M. Sar. 1997. Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells. Molecular Endocrinology 11(4): 450\u2013459.","journal-title":"Molecular Endocrinology"},{"issue":"8","key":"166_CR41","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1021\/jm00391a038","volume":"30","author":"J Templeton","year":"1987","unstructured":"Templeton, J., V. Kumar, D. Cote, D. Bose, D. Elliott, and R. Kim. 1987. Progesterone derivatives that bind to the digitalis receptor: synthesis of 14 beta-hydroxyprogesterone: A novel steroid with positive inotropic activity. Journal of Medicinal Chemistry 30(8): 1502\u20131505.","journal-title":"Journal of Medicinal Chemistry"},{"issue":"3","key":"166_CR42","first-page":"395","volume":"83","author":"W Wier","year":"1984","unstructured":"Wier, W., and P. Hess. 1984. Excitation-contraction coupling in cardiac Purkinje fibers effects of cardiotonic steroids on the intracellular [Ca2+] transient, membrane potential, and contraction. Journal of Phsiology 83(3): 395\u2013415.","journal-title":"Journal of Phsiology"}],"container-title":["Archives of Pharmacal Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12272-013-0166-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12272-013-0166-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12272-013-0166-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T20:06:47Z","timestamp":1563307607000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12272-013-0166-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,4]]},"references-count":42,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["166"],"URL":"https:\/\/doi.org\/10.1007\/s12272-013-0166-7","relation":{},"ISSN":["0253-6269","1976-3786"],"issn-type":[{"value":"0253-6269","type":"print"},{"value":"1976-3786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,4]]}}}