{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:23:17Z","timestamp":1789950197642,"version":"4.0.1"},"reference-count":28,"publisher":"The Microbiological Society of Korea","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Microbiol."],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s12275-018-7411-1","type":"journal-article","created":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T23:45:19Z","timestamp":1517442319000},"page":"145-149","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Effects of heat-killed Lactobacillus plantarum against influenza viruses in mice"],"prefix":"10.71150","volume":"56","author":[{"given":"Sehee","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Il","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon-Yong","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirim","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyunung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In-Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man-Seong","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilseob","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4586","published-online":{"date-parts":[[2018,2,2]]},"reference":[{"key":"7411_CR1","doi-asserted-by":"publisher","first-page":"937","DOI":"10.3109\/08923973.2012.672425","volume":"34","author":"Y. Arimori","year":"2012","unstructured":"Arimori, Y., Nakamura, R., Hirose, Y., Murosaki, S., Yamamoto, Y., Shidara, O., Ichikawa, H., and Yoshikai, Y. 2012. Daily intake of heat-killed Lactobacillus plantarum L-137 enhances type I interferon production in healthy humans and pigs. Immunopharmacol. Immunotoxicol. 34, 937\u2013943.","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"7411_CR2","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.3390\/v20801530","volume":"2","author":"N.M. Bouvier","year":"2010","unstructured":"Bouvier, N.M. and Lowen, A.C. 2010. Animal models for influenza virus pathogenesis and transmission. Viruses 2, 1530\u20131563.","journal-title":"Viruses"},{"key":"7411_CR3","volume-title":"Centers for disease control and prevention. Seasonal influenza vaccine effectiveness, 2005-2017","author":"CDC.","year":"2017","unstructured":"CDC. 2017. Centers for disease control and prevention. Seasonal influenza vaccine effectiveness, 2005-2017 (accessed: https:\/\/www. cdc.gov\/flu\/professionals\/vaccination\/effectiveness-studies.htm)."},{"key":"7411_CR4","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1017\/S0007114513001104","volume":"110","author":"H. Goto","year":"2013","unstructured":"Goto, H., Sagitani, A., Ashida, N., Kato, S., Hirota, T., Shinoda, T., and Yamamoto, N. 2013. Anti-influenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity. Br. J. Nutr. 110, 1810\u20131818.","journal-title":"Br. J. Nutr."},{"key":"7411_CR5","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.chom.2015.02.012","volume":"17","author":"K. Houser","year":"2015","unstructured":"Houser, K. and Subbarao, K. 2015. Influenza vaccines: challenges and solutions. Cell Host Microbe 17, 295\u2013300.","journal-title":"Cell Host Microbe"},{"key":"7411_CR6","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/j.intimp.2010.06.012","volume":"10","author":"T. Izumo","year":"2010","unstructured":"Izumo, T., Maekawa, T., Ida, M., Noguchi, A., Kitagawa, Y., Shibata, H., Yasui, H., and Kiso, Y. 2010. Effect of intranasal administration of Lactobacillus pentosus S-PT84 on influenza virus infection in mice. Int. Immunopharmacol. 10, 1101\u20131106.","journal-title":"Int. Immunopharmacol."},{"key":"7411_CR7","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1007\/s00253-014-5513-1","volume":"98","author":"J.Y. Jung","year":"2014","unstructured":"Jung, J.Y., Lee, S.H., and Jeon, C.O. 2014. Kimchi microflora: history, current status, and perspectives for industrial kimchi production. Appl. Microbiol. Biotechnol. 98, 2385\u20132393.","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"7411_CR8","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1016\/j.intimp.2011.08.013","volume":"11","author":"T. Kawashima","year":"2011","unstructured":"Kawashima, T., Hayashi, K., Kosaka, A., Kawashima, M., Igarashi, T., Tsutsui, H., Tsuji, N.M., Nishimura, I., Hayashi, T., and Obata, A. 2011. Lactobacillus plantarum strain YU from fermented foods activates Th1 and protective immune responses. Int. Immunopharmacol. 11, 2017\u20132024.","journal-title":"Int. Immunopharmacol."},{"key":"7411_CR9","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1128\/AEM.03075-12","volume":"79","author":"N. Kechaou","year":"2013","unstructured":"Kechaou, N., Chain, F., Gratadoux, J.J., Blugeon, S., Bertho, N., Chevalier, C., Le Goffic, R., Courau, S., Molimard, P., Chatel, J.M., et al. 2013. Identification of one novel candidate probiotic Lactobacillus plantarum strain active against influenza virus infection in mice by a large-scale screening. Appl. Environ. Microbiol. 79, 1491\u20131499.","journal-title":"Appl. Environ. Microbiol."},{"key":"7411_CR10","doi-asserted-by":"publisher","first-page":"86416","DOI":"10.1371\/journal.pone.0086416","volume":"9","author":"Y. Kikuchi","year":"2014","unstructured":"Kikuchi, Y., Kunitoh-Asari, A., Hayakawa, K., Imai, S., Kasuya, K., Abe, K., Adachi, Y., Fukudome, S., Takahashi, Y., and Hachimura, S. 2014. Oral administration of Lactobacillus plantarum strain AYA enhances IgA secretion and provides survival protection against influenza virus infection in mice. PLoS One 9, e86416.","journal-title":"PLoS One"},{"key":"7411_CR11","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1007\/s12275-013-3428-7","volume":"51","author":"J.I. Kim","year":"2013","unstructured":"Kim, J.I., Park, S., Lee, S., Lee, I., Heo, J., Hwang, M.W., Bae, J.Y., Kim, D., Jang, S.I., Park, M.S., et al. 2013. DBA\/2 mouse as an animal model for anti-influenza drug efficacy evaluation. J. Microbiol. 51, 866\u2013871.","journal-title":"J. Microbiol."},{"key":"7411_CR12","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1038\/srep01563","volume":"3","author":"M. Kiso","year":"2013","unstructured":"Kiso, M., Takano, R., Sakabe, S., Katsura, H., Shinya, K., Uraki, R., Watanabe, S., Saito, H., Toba, M., Kohda, N., et al. 2013. Protective efficacy of orally administered, heat-killed Lactobacillus pentosus b240 against influenza A virus. Sci. Rep. 3, 1563.","journal-title":"Sci. Rep."},{"key":"7411_CR13","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.intimp.2010.11.019","volume":"11","author":"N. Kobayashi","year":"2011","unstructured":"Kobayashi, N., Saito, T., Uematsu, T., Kishi, K., Toba, M., Kohda, N., and Suzuki, T. 2011. Oral administration of heat-killed Lactobacillus pentosus strain b240 augments protection against influenza virus infection in mice. Int. Immunopharmacol. 11, 199\u2013203.","journal-title":"Int. Immunopharmacol."},{"key":"7411_CR14","doi-asserted-by":"publisher","first-page":"469","DOI":"10.4014\/jmb.1511.11001","volume":"26","author":"H.A. Lee","year":"2016","unstructured":"Lee, H.A., Kim, H., Lee, K.W., and Park, K.Y. 2016. Dead Lactobacillus plantarum stimulates and skews immune responses toward T helper 1 and 17 polarizations in RAW 264.7 cells and mouse splenocytes. J. Microbiol. Biotechnol. 26, 469\u2013476.","journal-title":"J. Microbiol. Biotechnol."},{"key":"7411_CR15","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1016\/j.intimp.2009.04.015","volume":"9","author":"N. Maeda","year":"2009","unstructured":"Maeda, N., Nakamura, R., Hirose, Y., Murosaki, S., Yamamoto, Y., Kase, T., and Yoshikai, Y. 2009. Oral administration of heat-killed Lactobacillus plantarum L-137 enhances protection against influenza virus infection by stimulation of type I interferon production in mice. Int. Immunopharmacol. 9, 1122\u20131125.","journal-title":"Int. Immunopharmacol."},{"key":"7411_CR16","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1111\/j.1750-2659.2011.00231.x","volume":"5","author":"G. Neumann","year":"2011","unstructured":"Neumann, G. and Kawaoka, Y. 2011. The first influenza pandemic of the new millennium. Influenza Other Respir.Viruses 5, 157\u2013166.","journal-title":"Influenza Other Respir.Viruses"},{"key":"7411_CR17","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/S1473-3099(11)70295-X","volume":"12","author":"M.T. Osterholm","year":"2012","unstructured":"Osterholm, M.T., Kelley, N.S., Sommer, A., and Belongia, E.A. 2012. Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. Lancet. Infect. Dis. 12, 36\u201344.","journal-title":"Lancet. Infect. Dis."},{"key":"7411_CR18","doi-asserted-by":"publisher","first-page":"S82","DOI":"10.1038\/nm1141","volume":"10","author":"P. Palese","year":"2004","unstructured":"Palese, P. 2004. Influenza: old and new threats. Nat. Med. 10, S82\u2013S87.","journal-title":"Nat. Med."},{"key":"7411_CR19","volume-title":"Fields Virology","author":"P. Palese","year":"2013","unstructured":"Palese, P. and Shaw, M. 2013. Orthomyxoviridae. In Knipe, D.M. and Howley, P. (eds.), Fields Virology, 6th ed. Vol. 1. Wolters Kluwer Health\/Lippincott Williams & Wilkins, Philadelphia, USA.","edition":"6"},{"key":"7411_CR20","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.bbrc.2013.08.090","volume":"440","author":"S. Park","year":"2013","unstructured":"Park, S., Kim, J.I., Lee, I., Lee, S., Hwang, M.W., Bae, J.Y., Heo, J., Kim, D., Han, S.Z., and Park, M.S. 2013a. Aronia melanocarpa and its components demonstrate antiviral activity against influenza viruses. Biochem. Biophys. Res. Commun. 440, 14\u201319.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"7411_CR21","doi-asserted-by":"publisher","first-page":"284","DOI":"10.4167\/jbv.2012.42.4.284","volume":"42","author":"S. Park","year":"2012","unstructured":"Park, S., Kim, J.I., and Park, M.S. 2012. Antiviral agents against influenza viruses. J. Bacteriol. Virol. 42, 284\u2013293.","journal-title":"J. Bacteriol. Virol."},{"key":"7411_CR22","doi-asserted-by":"publisher","first-page":"75368","DOI":"10.1371\/journal.pone.0075368","volume":"8","author":"M.K. Park","year":"2013","unstructured":"Park, M.K., Ngo, V., Kwon, Y.M., Lee, Y.T., Yoo, S., Cho, Y.H., Hong, S.M., Hwang, H.S., Ko, E.J., Jung, Y.J., et al. 2013b. Lactobacillus plantarum DK119 as a probiotic confers protection against influenza virus by modulating innate immunity. PLoS One 8, e75368.","journal-title":"PLoS One"},{"key":"7411_CR23","doi-asserted-by":"publisher","first-page":"4709","DOI":"10.1016\/j.vaccine.2010.04.083","volume":"28","author":"J. Partridge","year":"2010","unstructured":"Partridge, J., Kieny, M.P., and World Health Organization, H.N.i.v.T.F. 2010. Global production of seasonal and pandemic (H1N1) influenza vaccines in 2009-2010 and comparison with previous estimates and global action plan targets. Vaccine 28, 4709\u20134712.","journal-title":"Vaccine"},{"key":"7411_CR24","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1111\/j.1365-2672.2012.05326.x","volume":"113","author":"B.J. Seo","year":"2012","unstructured":"Seo, B.J., Rather, I.A., Kumar, V.J., Choi, U.H., Moon, M.R., Lim, J.H., and Park, Y.H. 2012. Evaluation of Leuconostoc mesenteroides YML003 as a probiotic against low-pathogenic avian influenza (H9N2) virus in chickens. J. Appl. Microbiol. 113, 163\u2013171.","journal-title":"J. Appl. Microbiol."},{"key":"7411_CR25","doi-asserted-by":"publisher","first-page":"1976","DOI":"10.1016\/j.intimp.2011.08.007","volume":"11","author":"S. Takeda","year":"2011","unstructured":"Takeda, S., Takeshita, M., Kikuchi, Y., Dashnyam, B., Kawahara, S., Yoshida, H., Watanabe, W., Muguruma, M., and Kurokawa, M. 2011. Efficacy of oral administration of heat-killed probiotics from Mongolian dairy products against influenza infection in mice: alleviation of influenza infection by its immunomodulatory activity through intestinal immunity. Int. Immunopharmacol. 11, 1976\u20131983.","journal-title":"Int. Immunopharmacol."},{"key":"7411_CR26","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.jim.2014.03.023","volume":"410","author":"R.R. Thangavel","year":"2014","unstructured":"Thangavel, R.R. and Bouvier, N.M. 2014. Animal models for influenza virus pathogenesis, transmission, and immunology. J. Immunol. Methods 410, 60\u201379.","journal-title":"J. Immunol. Methods"},{"key":"7411_CR27","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1111\/lam.12160","volume":"58","author":"N. Waki","year":"2014","unstructured":"Waki, N., Yajima, N., Suganuma, H., Buddle, B.M., Luo, D., Heiser, A., and Zheng, T. 2014. Oral administration of Lactobacillus brevis KB290 to mice alleviates clinical symptoms following influenza virus infection. Lett. Appl. Microbiol. 58, 87\u201393.","journal-title":"Lett. Appl. Microbiol."},{"key":"7411_CR28","volume-title":"World Health Organization. vaccines against influenza","author":"WHO.","year":"2012","unstructured":"WHO. 2012. World Health Organization. vaccines against influenza. WHO position paper- November 2012 (accessed: http:\/\/www.who.int\/wer\/2012\/wer8747\/en\/)."}],"container-title":["Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12275-018-7411-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12275-018-7411-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12275-018-7411-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T12:48:34Z","timestamp":1735044514000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12275-018-7411-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["7411"],"URL":"https:\/\/doi.org\/10.1007\/s12275-018-7411-1","relation":{},"ISSN":["1225-8873","1976-3794"],"issn-type":[{"value":"1225-8873","type":"print"},{"value":"1976-3794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"27 September 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 December 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 February 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}