{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,25]],"date-time":"2024-12-25T05:24:31Z","timestamp":1735104271052,"version":"3.32.0"},"reference-count":53,"publisher":"The Microbiological Society of Korea","issue":"12","license":[{"start":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T00:00:00Z","timestamp":1569369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T00:00:00Z","timestamp":1569369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Microbiol."],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1007\/s12275-019-9177-5","type":"journal-article","created":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T15:41:28Z","timestamp":1569426088000},"page":"1056-1064","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Soft sweep development of resistance in Escherichia coli under fluoroquinolone stress"],"prefix":"10.71150","volume":"57","author":[{"given":"Xianxing","family":"Xie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruichen","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yajun","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanfeng","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujun","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruifu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4586","published-online":{"date-parts":[[2019,9,25]]},"reference":[{"key":"9177_CR1","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1038\/nrmicro2319","volume":"8","author":"DI Andersson","year":"2010","unstructured":"Andersson, D.I. and Hughes, D. 2010. Antibiotic resistance and its cost: is it possible to reverse resistance? Nat. Rev. Microbiol.8, 260\u2013271.","journal-title":"Nat. Rev. Microbiol."},{"key":"9177_CR2","doi-asserted-by":"publisher","first-page":"9170","DOI":"10.1073\/pnas.1708558114","volume":"114","author":"O Baltekin","year":"2017","unstructured":"Baltekin, O., Boucharin, A., Tano, E., Andersson, D.I., and Elf, J. 2017. Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging. Proc. Natl. Acad. Sci. USA114, 9170\u20139175.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"9177_CR3","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1111\/j.1365-2958.1994.tb01297.x","volume":"14","author":"RJ Belland","year":"1994","unstructured":"Belland, R.J., Morrison, S.G., Ison, C., and Huang, W.M. 1994. Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol. Microbiol.14, 371\u2013380.","journal-title":"Mol. Microbiol."},{"key":"9177_CR4","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/nmeth.f.303","volume":"7","author":"JG Caporaso","year":"2010","unstructured":"Caporaso J.G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F.D., Costello, E.K., Fierer, N., Pe\u00f1a, A.G., Goodrich, J.K., Gordon, J.I., et al. 2010. QIIME allows analysis of high-throughput community sequencing data. Nat Methods7, 335\u2013336.","journal-title":"Nat Methods"},{"key":"9177_CR5","volume-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard","author":"Clinical Laboratory Standards Institute","year":"2009","unstructured":"Clinical and Laboratory Standards Institute. 2009. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard. CLSI publication M07-A8. Wayne: Clinical and Laboratory Standards Institute."},{"key":"9177_CR6","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1093\/jac\/38.3.443","volume":"38","author":"S Conrad","year":"1996","unstructured":"Conrad, S., Oethinger, M., Kaifel, K., Klotz, G., Marre, R., and Kern, W.V. 1996. gyrA mutations in high-level fluoroquinolone-resistant clinical isolates of Escherichia coli. J. Antimicrob. Chemother.38, 443\u2013455.","journal-title":"J. Antimicrob. Chemother."},{"key":"9177_CR7","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1073\/pnas.1205750110","volume":"110","author":"Y Cui","year":"2013","unstructured":"Cui, Y., Yu, C., Yan, Y., Li, D., Li, Y., Jombart, T., Weinert, L.A., Wang, Z., Guo, Z., Xu, L., et al. 2013. Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis. Proc. Natl. Acad. Sci. USA110, 577\u2013582.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"9177_CR8","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/ng.806","volume":"43","author":"MA DePristo","year":"2011","unstructured":"DePristo, M.A., Banks, E., Poplin, R., Garimella, K.V., Maguire, J.R., Hartl, C., Philippakis, A.A., del Angel, G., Rivas, M.A., Hanna, M., et al. 2011. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat. Genet.43, 491\u2013498.","journal-title":"Nat. Genet."},{"key":"9177_CR9","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1093\/genetics\/148.4.1667","volume":"148","author":"JW Drake","year":"1998","unstructured":"Drake, J.W., Charlesworth, B., Charlesworth, D., and Crow, J.F. 1998. Rates of spontaneous mutation. Genetics148, 1667\u20131686.","journal-title":"Genetics"},{"key":"9177_CR10","doi-asserted-by":"publisher","first-page":"981","DOI":"10.2174\/156802609789630947","volume":"9","author":"K Drlica","year":"2009","unstructured":"Drlica, K., Hiasa, H., Kerns, R., Malik, M., Mustaev, A., and Zhao, X. 2009. Quinolones: action and resistance updated. Curr. Top. Med. Chem.9, 981\u2013998.","journal-title":"Curr. Top. Med. Chem."},{"key":"9177_CR11","first-page":"377","volume":"61","author":"K Drlica","year":"1997","unstructured":"Drlica, K. and Zhao, X. 1997. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol. Mol. Biol. Rev.61, 377\u2013392.","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"9177_CR12","doi-asserted-by":"publisher","first-page":"2194","DOI":"10.1093\/bioinformatics\/btr381","volume":"27","author":"RC Edgar","year":"2011","unstructured":"Edgar, R.C., Haas, B.J., Clemente, J.C., Quince, C., and Knight, R. 2011. UCHIME improves sensitivity and speed of chimera detection. Bioinformatics27, 2194\u20132200.","journal-title":"Bioinformatics"},{"key":"9177_CR13","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1128\/AAC.39.7.1554","volume":"39","author":"L Ferrero","year":"1995","unstructured":"Ferrero, L., Cameron, B., and Crouzet, J. 1995. Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus. Antimicrob. Agents Chemother.39, 1554\u20131558.","journal-title":"Antimicrob. Agents Chemother."},{"key":"9177_CR14","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.copbio.2018.01.026","volume":"54","author":"C Furusawa","year":"2018","unstructured":"Furusawa, C., Horinouchi, T., and Maeda, T. 2018. Toward prediction and control of antibiotic-resistance evolution. Curr. Opin. Biotechnol.54, 45\u201349.","journal-title":"Curr. Opin. Biotechnol."},{"key":"9177_CR15","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1186\/s13059-017-1252-9","volume":"18","author":"CP Harkins","year":"2017","unstructured":"Harkins, C.P., Pichon, B., Doumith, M., Parkhill, J., Westh, H., Tomasz, A., de Lencastre, H., Bentley, S.D., Kearns, A.M., and Holden, M.T.G. 2017. Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice. Genome Biol.18, 130.","journal-title":"Genome Biol."},{"key":"9177_CR16","doi-asserted-by":"publisher","first-page":"2335","DOI":"10.1534\/genetics.104.036947","volume":"169","author":"J Hermisson","year":"2005","unstructured":"Hermisson, J. and Pennings, P.S. 2005. Soft sweeps: molecular population genetics of adaptation from standing genetic variation. Genetics169, 2335\u20131352.","journal-title":"Genetics"},{"key":"9177_CR17","doi-asserted-by":"publisher","first-page":"S24","DOI":"10.1086\/314056","volume":"31","author":"DC Hooper","year":"2000","unstructured":"Hooper, D.C. 2000. Mechanisms of action and resistance of older and newer fluoroquinolones. Clin. Infect. Dis.31, S24\u201328.","journal-title":"Clin. Infect. Dis."},{"key":"9177_CR18","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3201\/eid0702.010239","volume":"7","author":"DC Hooper","year":"2001","unstructured":"Hooper, D.C. 2001. Emerging mechanisms of fluoroquinolone resistance. Emerg. Infect. Dis.7, 337\u2013341.","journal-title":"Emerg. Infect. Dis."},{"key":"9177_CR19","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.bios.2016.01.054","volume":"80","author":"T Huang","year":"2016","unstructured":"Huang, T., Zheng, Y., Yan, Y., Yang, L., Yao, Y., Zheng, J., Wu, L., Wang, X., Chen, Y., Xing, J., et al. 2016. Probing minority population of antibiotic-resistant bacteria. Biosens. Bioelectron.80, 323\u2013330.","journal-title":"Biosens. Bioelectron."},{"key":"9177_CR20","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/nrg3922","volume":"16","author":"D Hughes","year":"2015","unstructured":"Hughes, D. and Andersson, D.I. 2015. Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms. Nat. Rev. Genet.16, 459\u2013471.","journal-title":"Nat. Rev. Genet."},{"key":"9177_CR21","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1111\/mmi.12901","volume":"95","author":"M Jask\u00f3lska","year":"2015","unstructured":"Jask\u00f3lska, M. and Gerdes, K. 2015. CRP-dependent positive autoregulation and proteolytic degradation regulate competence activator Sxy of Escherichia coli. Mol. Microbiol.95, 833\u2013845.","journal-title":"Mol. Microbiol."},{"key":"9177_CR22","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/nature18313","volume":"534","author":"J Jee","year":"2016","unstructured":"Jee, J., Rasouly, A., Shamovsky, I., Akivis, Y., Steinman, S.R., Mishra, B., and Nudler, E. 2016. Rates and mechanisms of bacterial mutagenesis from maximum-depth sequencing. Nature534, 693\u2013696.","journal-title":"Nature"},{"key":"9177_CR23","doi-asserted-by":"publisher","first-page":"5281","DOI":"10.1038\/ncomms6281","volume":"5","author":"JD Jensen","year":"2014","unstructured":"Jensen, J.D. 2014. On the unfounded enthusiasm for soft selective sweeps. Nat. Commun.5, 5281.","journal-title":"Nat. Commun."},{"key":"9177_CR24","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.phrp.2012.04.004","volume":"3","author":"J Kim","year":"2012","unstructured":"Kim, J., Jeon, S., Kim, H., Park, M., Kim, S., and Kim, S. 2012. Multiplex real-time polymerase chain reaction-based method for the rapid detection of gyrA and parC mutations in quinolone-resistant Escherichia coli and Shigella spp. Osong Public Health Res. Perspect.3, 113\u2013117.","journal-title":"Osong Public Health Res. Perspect."},{"key":"9177_CR25","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1038\/nrg.2017.68","volume":"18","author":"L Koch","year":"2017","unstructured":"Koch, L. 2017. Pathogen genetics: evolutionary dynamics driving drug resistance. Nat. Rev. Genet.18, 578\u2013579.","journal-title":"Nat. Rev. Genet."},{"key":"9177_CR26","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.1128\/AAC.47.10.3222-3232.2003","volume":"47","author":"P Komp Lindgren","year":"2003","unstructured":"Komp Lindgren, P., Karlsson, A., and Hughes, D. 2003. Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections. Antimicrob. Agents Chemother.47, 3222\u20133232.","journal-title":"Antimicrob. Agents Chemother."},{"key":"9177_CR27","doi-asserted-by":"publisher","first-page":"R12","DOI":"10.1186\/gb-2004-5-2-r12","volume":"5","author":"S Kurtz","year":"2004","unstructured":"Kurtz, S., Phillippy, A., Delcher, A.L., Smoot, M., Shumway, M., Antonescu, C., and Salzberg, S.L. 2004. Versatile and open software for comparing large genomes. Genome Biol.5, R12.","journal-title":"Genome Biol."},{"key":"9177_CR28","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1038\/ismej.2017.69","volume":"11","author":"RE Lenski","year":"2017","unstructured":"Lenski, R.E. 2017. Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations. ISME J.11, 2181\u20132194.","journal-title":"ISME J."},{"key":"9177_CR29","doi-asserted-by":"publisher","first-page":"4460","DOI":"10.1128\/AAC.48.11.4460-4462.2004","volume":"48","author":"X Li","year":"2004","unstructured":"Li, X., Mariano, N., Rahal, J.J., Urban, C.M., and Drlica, K. 2004. Quinolone-resistant Haemophilus influenzae: determination of mutant selection window for ciprofloxacin, garenoxacin, levofloxacin, and moxifloxacin. Antimicrob. Agents Chemother.48, 4460\u20134462.","journal-title":"Antimicrob. Agents Chemother."},{"key":"9177_CR30","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1101\/gr.097261.109","volume":"20","author":"R Li","year":"2009","unstructured":"Li, R., Zhu, H., Ruan, J., Qian, W., Fang, X., Shi, Z., Li, Y., Li, S., Shan, G., Kristiansen, K., et al. 2009. De novo assembly of human genomes with massively parallel short read sequencing. Genome Res.20, 265\u2013272.","journal-title":"Genome Res."},{"key":"9177_CR31","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.envint.2018.07.035","volume":"120","author":"W Lin","year":"2018","unstructured":"Lin, W., Zeng, J., Wan, K., Lv, L., Guo, L., Li, X., and Yu, X. 2018. Reduction of the fitness cost of antibiotic resistance caused by chromosomal mutations under poor nutrient conditions. Environ. Int.120, 63\u201371.","journal-title":"Environ. Int."},{"key":"9177_CR32","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1038\/nrmicro.2018.33","volume":"16","author":"SW Lo","year":"2018","unstructured":"Lo, S.W., Kumar, N., and Wheeler, N.E. 2018. Breaking the code of antibiotic resistance. Nat. Rev. Microbiol.16, 262.","journal-title":"Nat. Rev. Microbiol."},{"key":"9177_CR33","doi-asserted-by":"publisher","first-page":"E2498","DOI":"10.1073\/pnas.1601208113","volume":"113","author":"H Long","year":"2016","unstructured":"Long, H., Miller, S.F., Strauss, C., Zhao, C., Cheng, L., Ye, Z., Griffin, K., Te, R., Lee, H., Chen, C.C., et al. 2016. Antibiotic treatment enhances the genome-wide mutation rate of target cells. Proc. Natl. Acad. Sci. USA113, E2498\u20132505.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"9177_CR34","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1365-2958.2007.05642.x","volume":"64","author":"E L\u00f3pez","year":"2007","unstructured":"L\u00f3pez, E., Elez, M., Matic, I., and Bl\u00e1zquez, J. 2007. Antibiotic-mediated recombination: ciprofloxacin stimulates SOS-independent recombination of divergent sequences in Escherichia coli. Mol. Microbiol.64, 83\u201393.","journal-title":"Mol. Microbiol."},{"key":"9177_CR35","doi-asserted-by":"publisher","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","volume":"27","author":"T Magoc","year":"2011","unstructured":"Magoc, T. and Salzberg, S.L. 2011. FLASH: fast length adjustment of short reads to improve genome assemblies. Bioinformatics27, 2957\u20132963.","journal-title":"Bioinformatics"},{"key":"9177_CR36","doi-asserted-by":"publisher","first-page":"e1000541","DOI":"10.1371\/journal.ppat.1000541","volume":"5","author":"LL Marcusson","year":"2009","unstructured":"Marcusson, L.L., Frimodt-Moller, N., and Hughes, D. 2009. Interplay in the selection of fluoroquinolone resistance and bacterial fitness. PLoS Pathog.5, e1000541.","journal-title":"PLoS Pathog."},{"key":"9177_CR37","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.coph.2011.07.005","volume":"11","author":"JL Martinez","year":"2011","unstructured":"Martinez, J.L., Baquero, F., and Andersson, D.I. 2011. Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics. Curr. Opin. Pharmacol.11, 439\u2013445.","journal-title":"Curr. Opin. Pharmacol."},{"key":"9177_CR38","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.tree.2013.08.003","volume":"28","author":"PW Messer","year":"2013","unstructured":"Messer, P.W. and Petrov, D.A. 2013. Population genomics of rapid adaptation by soft selective sweeps. Trends Ecol. Evol.28, 659\u2013669.","journal-title":"Trends Ecol. Evol."},{"key":"9177_CR39","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1128\/JCM.02434-14","volume":"53","author":"A Mezger","year":"2015","unstructured":"Mezger, A., Gullberg, E., Goransson, J., Zorzet, A., Herthnek, D., Tano, E., Nilsson, M., Andersson, D.I. 2015. A general method for rapid determination of antibiotic susceptibility and species in bacterial infections. J. Clin. Microbiol.53, 425\u2013432.","journal-title":"J. Clin. Microbiol."},{"key":"9177_CR40","doi-asserted-by":"publisher","first-page":"e01285","DOI":"10.1128\/mBio.01285-14","volume":"5","author":"DK O\u2019Toole","year":"2014","unstructured":"O\u2019Toole, D.K. 2014. The natural environment may be the most important source of antibiotic resistance genes. MBio5, e01285\u201314.","journal-title":"MBio"},{"key":"9177_CR41","doi-asserted-by":"publisher","first-page":"e1790","DOI":"10.1371\/journal.pntd.0001790","volume":"6","author":"L Pallecchi","year":"2012","unstructured":"Pallecchi, L., Bartoloni, A., Riccobono, E., Fernandez, C., Mantella, A., Magnelli, D., Mannini, D., Strohmeyer, M., Bartalesi, F., Rodriguez, H., et al. 2012. Quinolone resistance in absence of selective pressure: the experience of a very remote community in the Amazon forest. PLoS Negl. Trop. Dis.6, e1790.","journal-title":"PLoS Negl. Trop. Dis."},{"key":"9177_CR42","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1093\/molbev\/msj117","volume":"23","author":"PS Pennings","year":"2006","unstructured":"Pennings, P.S. and Hermisson, J. 2006a. Soft sweeps II-molecular population genetics of adaptation from recurrent mutation or migration. Mol. Biol. Evol.23, 1076\u20131084.","journal-title":"Mol. Biol. Evol."},{"key":"9177_CR43","doi-asserted-by":"publisher","first-page":"e186","DOI":"10.1371\/journal.pgen.0020186","volume":"2","author":"PS Pennings","year":"2006","unstructured":"Pennings, P.S. and Hermisson, J. 2006b. Soft sweeps III: the signature of positive selection from recurrent mutation. PLoS Genet.2, e186.","journal-title":"PLoS Genet."},{"key":"9177_CR44","doi-asserted-by":"publisher","first-page":"e35620","DOI":"10.1371\/journal.pone.0035620","volume":"7","author":"AR Poteete","year":"2012","unstructured":"Poteete, A.R., Sinha, S., and Redfield, R.J. 2012. Natural DNA uptake by Escherichia coli. PLoS One7, e35620.","journal-title":"PLoS One"},{"key":"9177_CR45","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.tim.2014.04.007","volume":"22","author":"LS Redgrave","year":"2014","unstructured":"Redgrave, L.S., Sutton, S.B., Webber, M.A., and Piddock, L.J. 2014. Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success. Trends Microbiol.22, 438\u2013445.","journal-title":"Trends Microbiol."},{"key":"9177_CR46","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/S0732-8893(01)00357-1","volume":"42","author":"J Ruiz","year":"2002","unstructured":"Ruiz, J., Gomez, J., Navia, M.M., Ribera, A., Sierra, J.M., Marco, F., Mensa, J., Vila, J., et al. 2002. High prevalence of nalidixic acid resistant, ciprofloxacin susceptible phenotype among clinical isolates of Escherichia coli and other Enterobacteriaceae. Diagn. Microbiol. Infect. Dis.42, 257\u2013261.","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"9177_CR47","doi-asserted-by":"publisher","first-page":"14508","DOI":"10.1073\/pnas.1208715109","volume":"109","author":"MW Schmitt","year":"2012","unstructured":"Schmitt, M.W., Kennedy, S.R., Salk, J.J., Fox, E.J., Hiatt, J.B., and Loeb, L.A. 2012. Detection of ultra-rare mutations by next-generation sequencing. Proc. Natl. Acad. Sci. USA109, 14508\u201314513.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"9177_CR48","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/0168-9525(96)10014-7","volume":"12","author":"J Solomon","year":"1996","unstructured":"Solomon, J. and Grossman, A. 1996. Who\u2019s competent and when: regulation of natural genetic competence in bacteria. Trends Genet.12, 150\u2013155.","journal-title":"Trends Genet."},{"key":"9177_CR49","first-page":"e01421","volume":"5","author":"F Wichmann","year":"2014","unstructured":"Wichmann, F., Udikovik-Kolic, N., Andrew, S., and Handelsman, J. 2014. Reply to \u201cThe natural environment may be the most important source of antibiotic resistance genes\u201d. MBio5, e01421\u201314.","journal-title":"MBio"},{"key":"9177_CR50","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1534\/genetics.116.191478","volume":"205","author":"BA Wilson","year":"2017","unstructured":"Wilson, B.A., Pennings, P.S., and Petrov, D.A. 2017. Soft selective sweeps in evolutionary rescue. Genetics205, 1573\u20131586.","journal-title":"Genetics"},{"key":"9177_CR51","first-page":"e01336","volume":"61","author":"K Yamada","year":"2017","unstructured":"Yamada, K., Saito, R., Muto, S., Kashiwa, M., Tamamori, Y., and Fujisaki, S. 2017. Molecular characterization of fluoroquinolone-resistant Moraxella catarrhalis variants generated in vitro by step-wise selection. Antimicrob. Agents Chemother.61, e01336\u201317.","journal-title":"Antimicrob. Agents Chemother."},{"key":"9177_CR52","doi-asserted-by":"publisher","first-page":"2499","DOI":"10.1093\/jac\/dkv134","volume":"70","author":"G Zhang","year":"2015","unstructured":"Zhang, G., Wang, C., Sui, Z., and Feng, J. 2015. Insights into the evolutionary trajectories of fluoroquinolone resistance in Streptococcus pneumoniae. J. Antimicrob. Chemother.70, 2499\u20132506.","journal-title":"J. Antimicrob. Chemother."},{"key":"9177_CR53","doi-asserted-by":"publisher","first-page":"S147","DOI":"10.1086\/321841","volume":"33","author":"X Zhao","year":"2001","unstructured":"Zhao, X. and Drlica, K. 2001. Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies. Clin. Infect. Dis.33, S147\u2013156.","journal-title":"Clin. Infect. Dis."}],"container-title":["Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12275-019-9177-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12275-019-9177-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12275-019-9177-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T17:49:08Z","timestamp":1735062548000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12275-019-9177-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,25]]},"references-count":53,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["9177"],"URL":"https:\/\/doi.org\/10.1007\/s12275-019-9177-5","relation":{},"ISSN":["1225-8873","1976-3794"],"issn-type":[{"type":"print","value":"1225-8873"},{"type":"electronic","value":"1976-3794"}],"subject":[],"published":{"date-parts":[[2019,9,25]]},"assertion":[{"value":"4 April 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}