{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:37:03Z","timestamp":1791232623491,"version":"4.1.0"},"reference-count":69,"publisher":"The Microbiological Society of Korea","issue":"11","license":[{"start":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T00:00:00Z","timestamp":1633478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T00:00:00Z","timestamp":1633478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Microbiol."],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1007\/s12275-021-1271-9","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T23:10:50Z","timestamp":1633648250000},"page":"988-1001","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The comparison of microbial communities in thyroid tissues from thyroid carcinoma patients"],"prefix":"10.71150","volume":"59","author":[{"given":"Chen-Jian","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Qian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Yao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Lun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Dan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun-Xian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Ran","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4586","published-online":{"date-parts":[[2021,10,6]]},"reference":[{"key":"1271_CR1","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1002\/ijc.2910530202","volume":"53","author":"LA Akslen","year":"1993","unstructured":"Akslen, L.A., Haldorsen, T., Thoresen, S.O., and Glattre, E. 1993. Incidence pattern of thyroid cancer in Norway: influence of birth cohort and time period. Int. J. Cancer 53, 183\u2013187.","journal-title":"Int. J. Cancer"},{"key":"1271_CR2","doi-asserted-by":"publisher","first-page":"1941710","DOI":"10.1080\/19490976.2021.1941710","volume":"13","author":"M Avril","year":"2021","unstructured":"Avril, M. and Depaolo, R.W. 2021. \u201cDriver-passenger\u201d bacteria and their metabolites in the pathogenesis of colorectal cancer. Gut Microbes 13, 1941710.","journal-title":"Gut Microbes"},{"key":"1271_CR3","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1471-2105-4-2","volume":"4","author":"GD Bader","year":"2003","unstructured":"Bader, G.D. and Hogue, C.W.V. 2003. An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinformatics 4, 2.","journal-title":"BMC Bioinformatics"},{"key":"1271_CR4","doi-asserted-by":"publisher","first-page":"5064","DOI":"10.1128\/AEM.64.12.5064-5066.1998","volume":"64","author":"CF Brunk","year":"1998","unstructured":"Brunk, C.F. and Eis, N. 1998. Quantitative measure of small-sub-unit rRNA gene sequences of the kingdom Korarchaeota. Appl. Environ. Microbiol. 64, 5064\u20135066.","journal-title":"Appl. Environ. Microbiol."},{"key":"1271_CR5","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/nmeth.f.303","volume":"7","author":"JG Caporaso","year":"2010","unstructured":"Caporaso, J.G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F.D., Costello, E.K., Fierer, N., Pe\u00f1a, A.G., Goodrich, J.K., Gordon, J.I., et al. 2010. QIIME allows analysis of high-throughput community sequencing data. Nat. Methods 7, 335\u2013336.","journal-title":"Nat. Methods"},{"key":"1271_CR6","doi-asserted-by":"publisher","first-page":"3095","DOI":"10.1007\/s00253-018-8871-2","volume":"102","author":"PP Chaudhary","year":"2018","unstructured":"Chaudhary, P.P., Conway, P.L., and Schlundt, J. 2018. Methanogens in humans: potentially beneficial or harmful for health. Appl. Microbiol. Biotechnol. 102, 3095\u20133104.","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"1271_CR7","doi-asserted-by":"publisher","first-page":"e105001","DOI":"10.1371\/journal.pone.0105001","volume":"9","author":"F Cumbo","year":"2014","unstructured":"Cumbo, F., Paci, P., Santoni, D., Di Paola, L., and Giuliani, A. 2014. GIANT: a cytoscape plugin for modular networks. PLoS ONE 9, e105001.","journal-title":"PLoS ONE"},{"key":"1271_CR8","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.ijfoodmicro.2016.02.004","volume":"223","author":"M Dzieciol","year":"2016","unstructured":"Dzieciol, M., Schornsteiner, E., Meryem-Uyar, M., Stessl, B., Wagner, M., and Schmitz-Esser, S. 2016. Bacterial diversity of floor drain biofilms and drain waters in a Listeria monocytogenes contaminated food processing environment. Int. J. Food Microbiol. 223, 33\u201340.","journal-title":"Int. J. Food Microbiol."},{"key":"1271_CR9","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1097\/MCG.0b013e3181d6bc3e","volume":"44","author":"EC Ebert","year":"2010","unstructured":"Ebert, E.C. 2010. The thyroid and the gut. J. Clin. Gastroenterol. 44, 402\u2013406.","journal-title":"J. Clin. Gastroenterol."},{"key":"1271_CR10","doi-asserted-by":"publisher","first-page":"102","DOI":"10.3389\/fimmu.2013.00102","volume":"4","author":"AM Faria","year":"2013","unstructured":"Faria, A.M., Gomes-Santos, A.C., Gon\u00e7alves, J.L., Moreira, T.G., Medeiros, S.R., Dourado, L.P.A., and Cara, D.C. 2013. Food components and the immune system: from tonic agents to allergens. Front. Immunol. 4, 102.","journal-title":"Front. Immunol."},{"key":"1271_CR11","doi-asserted-by":"publisher","first-page":"e1002606","DOI":"10.1371\/journal.pcbi.1002606","volume":"8","author":"K Faust","year":"2012","unstructured":"Faust, K., Sathirapongsasuti, J.F., Izard, J., Segata, N., Gevers, D., Raes, J., and Huttenhower, C. 2012. Microbial co-occurrence relationships in the human microbiome. PLoS Comput. Biol. 8, e1002606.","journal-title":"PLoS Comput. Biol."},{"key":"1271_CR12","doi-asserted-by":"publisher","first-page":"2728","DOI":"10.1002\/ijc.32007","volume":"144","author":"J Feng","year":"2019","unstructured":"Feng, J., Zhao, F., Sun, J., Lin, B., Zhao, L., Liu, Y., Jin, Y., Li, S., Li, A., and Wei, Y. 2019. Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients. Int. J. Cancer 144, 2728\u20132745.","journal-title":"Int. J. Cancer"},{"key":"1271_CR13","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1111\/j.1600-0587.2010.06548.x","volume":"34","author":"PVA Fine","year":"2011","unstructured":"Fine, P.V.A. and Kembel, S.W. 2011. Phylogenetic community structure and phylogenetic turnover across space and edaphic gradients in western Amazonian tree communities. Ecography 34, 552\u2013565.","journal-title":"Ecography"},{"key":"1271_CR14","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1042\/CS20160876","volume":"131","author":"J Gagni\u00e8re","year":"2017","unstructured":"Gagni\u00e8re, J., Bonnin, V., Jarrousse, A.S., Cardamone, E., Agus, A., Uhrhammer, N., Sauvanet, P., Dechelotte, P., Barnich, N., Bonnet, M., et al. 2017. Interactions between microsatellite instability and human gut colonization by Escherichia coli in colorectal cancer. Clin. Sci. 131, 471\u2013485.","journal-title":"Clin. Sci."},{"key":"1271_CR15","doi-asserted-by":"publisher","first-page":"e30126","DOI":"10.1371\/journal.pone.0030126","volume":"7","author":"I Holmes","year":"2012","unstructured":"Holmes, I., Harris, K., and Quince, C. 2012. Dirichlet multinomial mixtures: generative models for microbial metagenomics. PLoS ONE 7, e30126.","journal-title":"PLoS ONE"},{"key":"1271_CR16","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1016\/j.jnutbio.2008.06.009","volume":"20","author":"J Hrdina","year":"2009","unstructured":"Hrdina, J., Banning, A., Kipp, A., Loh, G., Blaut, M., and Brigelius-Floh\u00e9, R. 2009. The gastrointestinal microbiota affects the selenium status and selenoprotein expression in mice. J. Nutr. Biochem. 20, 638\u2013648.","journal-title":"J. Nutr. Biochem."},{"key":"1271_CR17","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1007\/s11427-016-5083-9","volume":"59","author":"X Hu","year":"2016","unstructured":"Hu, X., Wang, T., and Jin, F. 2016. Alzheimer\u2019s disease and gut microbiota. Sci. China Life Sci. 59, 1006\u20131023.","journal-title":"Sci. China Life Sci."},{"key":"1271_CR18","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1111\/j.0269-8463.2005.00965.x","volume":"19","author":"SP Hubbell","year":"2005","unstructured":"Hubbell, S.P. 2005. Neutral theory in community ecology and the hypothesis of functional equivalence. Funct. Ecol. 19, 166\u2013172.","journal-title":"Funct. Ecol."},{"key":"1271_CR19","doi-asserted-by":"publisher","first-page":"2655","DOI":"10.1038\/s41467-018-05184-7","volume":"9","author":"MA Jackson","year":"2018","unstructured":"Jackson, M.A., Verdi, S., Maxan, M.E., Shin, C.M., Zierer, J., Bowyer, R.C.E., Martin, T., Williams, F.M.K., Menni, C., Bell, J.T., et al. 2018. Gut microbiota associations with common diseases and prescription medications in a population-based cohort. Nat. Commun. 9, 2655.","journal-title":"Nat. Commun."},{"key":"1271_CR20","doi-asserted-by":"publisher","first-page":"282","DOI":"10.3389\/fimmu.2019.00282","volume":"10","author":"B Jia","year":"2019","unstructured":"Jia, B. 2019. Commentary: gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Front. Immunol. 10, 282.","journal-title":"Front. Immunol."},{"key":"1271_CR21","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1093\/bioinformatics\/btq166","volume":"26","author":"SW Kembel","year":"2010","unstructured":"Kembel, S.W., Cowan, P.D., Helmus, M.R., Cornwell, W.K., Morlon, H., Ackerly, D.D., Blomberg, S.P., and Webb, C.O. 2010. Picante: R tools for integrating phylogenies and ecology. Bioinformatics 26, 1463\u20131464.","journal-title":"Bioinformatics"},{"key":"1271_CR22","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.3390\/nu12061769","volume":"12","author":"J Knezevic","year":"2020","unstructured":"Knezevic, J., Starchl, C., Tmava Berisha, A., and Amrein, K. 2020. Thyroid-gut-axis: how does the microbiota influence thyroid function? Nutrients 12, 1769.","journal-title":"Nutrients"},{"key":"1271_CR23","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1093\/molbev\/msy096","volume":"35","author":"S Kumar","year":"2018","unstructured":"Kumar, S., Stecher, G., Li, M., Knyaz, C., and Tamura, K. 2018. MEGA X: molecular evolutionary genetics analysis across computing platforms. Mol. Biol. Evol. 35, 1547\u20131549.","journal-title":"Mol. Biol. Evol."},{"key":"1271_CR24","doi-asserted-by":"publisher","first-page":"4180","DOI":"10.1210\/jc.2007-0606","volume":"92","author":"EC Lauritano","year":"2007","unstructured":"Lauritano, E.C., Bilotta, A.L., Gabrielli, M., Scarpellini, E., Lupascu, A., Laginestra, A., Novi, M., Sottili, S., Serricchio, M., Cammarota, G., et al. 2007. Association between hypothyroidism and small intestinal bacterial overgrowth. J. Clin. Endocrinol. Metab. 92, 4180\u20134184.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"1271_CR25","doi-asserted-by":"publisher","first-page":"20","DOI":"10.3390\/toxins11010020","volume":"11","author":"Y Leshem","year":"2019","unstructured":"Leshem, Y. and Pastan, I. 2019. Pseudomonas exotoxin immunotoxins and anti-tumor immunity: from observations at the patient\u2019s bedside to evaluation in preclinical models. Toxins 11, 20.","journal-title":"Toxins"},{"key":"1271_CR26","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1111\/ele.12476","volume":"18","author":"S Li","year":"2015","unstructured":"Li, S., Cadotte, M., Meiners, S., Hua, Z., Jiang, L., and Shu, W. 2015. Species colonisation, not competitive exclusion, drives community overdispersion over long-term succession. Ecol. Lett. 18, 964\u2013973.","journal-title":"Ecol. Lett."},{"key":"1271_CR27","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1054\/bjoc.2001.2061","volume":"85","author":"S Liu","year":"2001","unstructured":"Liu, S., Semenciw, R., Ugnat, A.M., and Mao, Y. 2001. Increasing thyroid cancer incidence in Canada, 1970\u20131996: time trends and age-period-cohort effects. Br. J. Cancer 85, 1335\u20131339.","journal-title":"Br. J. Cancer"},{"key":"1271_CR28","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1089\/thy.2014.0294","volume":"25","author":"SC Londero","year":"2015","unstructured":"Londero, S.C., Krogdahl, A., Bastholt, L., Overgaard, J., Pedersen, H.B., Hahn, C.H., Bentzen, J., Schytte, S., Christiansen, P., Gerke, O., et al. 2015. Papillary thyroid carcinoma in Denmark, 1996\u20132008: outcome and evaluation of established prognostic scoring systems in a prospective national cohort. Thyroid 25, 78\u201384.","journal-title":"Thyroid"},{"key":"1271_CR29","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1089\/thy.2006.16.1033","volume":"16","author":"A Lubina","year":"2006","unstructured":"Lubina, A., Cohen, O., Barchana, M., Liphshiz, I., Vered, I., Sadetzki, S., and Karasik, A. 2006. Time trends of incidence rates of thyroid cancer in Israel: what might explain the sharp increase. Thyroid 16, 1033\u20131040.","journal-title":"Thyroid"},{"key":"1271_CR30","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3389\/fcimb.2013.00115","volume":"3","author":"P Markou","year":"2014","unstructured":"Markou, P. and Apidianakis, Y. 2014. Pathogenesis of intestinal Pseudomonas aeruginosa infection in patients with cancer. Front. Cell. Infect. Microbiol. 3, 115.","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"1271_CR31","doi-asserted-by":"publisher","first-page":"A31","DOI":"10.1136\/jech.2010.120956.79","volume":"64","author":"RJQ McNally","year":"2010","unstructured":"McNally, R.J.Q., Blakey, K., James, P.W., Pozo, B.G., Basta, N.O., and Hale, J. 2010. Increasing incidence of thyroid cancer in Great Britain, 1976\u20132005: age-period-cohort analysis. J. Epidemiol. Community Health 64, A31. https:\/\/jech.bmj.com\/content\/64\/Suppl_1\/A31.2.","journal-title":"J. Epidemiol. Community Health"},{"key":"1271_CR32","doi-asserted-by":"publisher","first-page":"7379","DOI":"10.1038\/ncomms8379","volume":"6","author":"D Montoya","year":"2015","unstructured":"Montoya, D., Yallop, M.L., and Memmott, J. 2015. Functional group diversity increases with modularity in complex food webs. Nat. Commun. 6, 7379.","journal-title":"Nat. Commun."},{"key":"1271_CR33","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1126\/science.aay9189","volume":"368","author":"D Nejman","year":"2020","unstructured":"Nejman, D., Livyatan, I., Fuks, G., Gavert, N., Zwang, Y., Geller, L.T., Rotter-Maskowitz, A., Weiser, R., Mallel, G., Gigi, E., et al. 2020. The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science 368, 973\u2013980.","journal-title":"Science"},{"key":"1271_CR34","unstructured":"NIH\/National Cancer Institute. 2018. Gut microbiome can control antitumor immune function in liver. Science Daily. www.science-daily.com\/releases\/2018\/05\/180524141715.htm."},{"key":"1271_CR35","doi-asserted-by":"publisher","first-page":"S37","DOI":"10.1038\/modpathol.2008.10","volume":"21","author":"YE Nikiforov","year":"2008","unstructured":"Nikiforov, Y.E. 2008. Thyroid carcinoma: molecular pathways and therapeutic targets. Mod. Pathol. 21, S37\u2013S43.","journal-title":"Mod. Pathol."},{"key":"1271_CR36","doi-asserted-by":"crossref","unstructured":"Nussey, S. and Whitehead, S. 2001. Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers, Milton Park, England. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK22\/.","DOI":"10.1201\/b15306"},{"key":"1271_CR37","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1038\/nrgastro.2016.165","volume":"13","author":"SJD O\u2019Keefe","year":"2016","unstructured":"O\u2019Keefe, S.J.D. 2016. Diet, microorganisms and their metabolites, and colon cancer. Nat. Rev. Gastroenterol. Hepatol. 13, 691\u2013706.","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"1271_CR38","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1007\/s00405-010-1416-7","volume":"268","author":"O Olaleye","year":"2011","unstructured":"Olaleye, O., Ekrikpo, U., Moorthy, R., Lyne, O., Wiseberg, J., Black, M., and Mitchell, D. 2011. Increasing incidence of differentiated thyroid cancer in South East England: 1987\u20132006. Eur. Arch. Otorhinolaryngol. 268, 899\u2013906.","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"1271_CR39","doi-asserted-by":"publisher","first-page":"e00019","DOI":"10.1128\/CMR.00019-18","volume":"31","author":"MD Parkins","year":"2018","unstructured":"Parkins, M.D., Somayaji, R., and Waters, V.J. 2018. Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis. Clin. Microbiol. Rev. 31, e00019\u201318.","journal-title":"Clin. Microbiol. Rev."},{"key":"1271_CR40","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1094\/PHYTO-02-16-0058-FI","volume":"106","author":"R Poudel","year":"2016","unstructured":"Poudel, R., Jumpponen, A., Schlatter, D.C., Paulitz, T.C., McSpadden Gardener, B.B., Kinkel, L.L., and Garrett, K.A. 2016. Microbiome networks: a systems framework for identifying candidate microbial assemblages for disease management. Phytopathology 106, 1083\u20131096.","journal-title":"Phytopathology"},{"key":"1271_CR41","doi-asserted-by":"publisher","first-page":"7188","DOI":"10.1093\/nar\/gkm864","volume":"35","author":"E Pruesse","year":"2007","unstructured":"Pruesse, E., Quast, C., Knittel, K., Fuchs, B.M., Ludwig, W., Peplies, J., and Gl\u00f6ckner, F.O. 2007. SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB. Nucleic Acids Res. 35, 7188\u20137196.","journal-title":"Nucleic Acids Res."},{"key":"1271_CR42","first-page":"262","volume":"29","author":"TV Pryzimirska","year":"2007","unstructured":"Pryzimirska, T.V., Pogribny, I.P., and Chekhun, V.F. 2007. The impact of tumor growth on plasma homocysteine levels and tissue-specific DNA methylation in Walker-256 tumor-bearing rats. Exp. Oncol. 29, 262\u2013266.","journal-title":"Exp. Oncol."},{"key":"1271_CR43","doi-asserted-by":"publisher","first-page":"2913","DOI":"10.1158\/0008-5472.CAN-14-0155","volume":"74","author":"L Rahib","year":"2014","unstructured":"Rahib, L., Smith, B.D., Aizenberg, R., Rosenzweig, A.B., Fleshman, J.M., and Matrisian, L.M. 2014. Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States. Cancer Res 74, 2913\u20132921.","journal-title":"Cancer Res"},{"key":"1271_CR44","doi-asserted-by":"publisher","first-page":"3417","DOI":"10.1128\/aem.58.10.3417-3418.1992","volume":"58","author":"AL Reysenbach","year":"1992","unstructured":"Reysenbach, A.L., Giver, L.J., Wickham, G.S., and Pace, N.R. 1992. Differential amplification of rRNA genes by polymerase chain reaction. Appl. Environ. Microbiol. 58, 3417\u20133418.","journal-title":"Appl. Environ. Microbiol."},{"key":"1271_CR45","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1093\/jjco\/hyu179","volume":"44","author":"K Saika","year":"2014","unstructured":"Saika, K., Matsuda, T., and Sobue, T. 2014. Incidence rate of thyroid cancer by histological type in Japan. Jpn. J. Clin. Oncol. 44, 1131\u20131132.","journal-title":"Jpn. J. Clin. Oncol."},{"key":"1271_CR46","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1128\/CMR.00044-14","volume":"27","author":"BS Scales","year":"2014","unstructured":"Scales, B.S., Dickson, R.P., LiPuma, J.J., and Huffnagle, G.B. 2014. Microbiology, genomics, and clinical significance of the Pseudomonas fluorescens species complex, an unappreciated colonizer of humans. Clin. Microbiol. Rev. 27, 927\u2013948.","journal-title":"Clin. Microbiol. Rev."},{"key":"1271_CR47","doi-asserted-by":"publisher","first-page":"7537","DOI":"10.1128\/AEM.01541-09","volume":"75","author":"PD Schloss","year":"2009","unstructured":"Schloss, P.D., Westcott, S.L., Ryabin, T., Hall, J.R., Hartmann, M., Hollister, E.B., Lesniewski, R.A., Oakley, B.B., Parks, D.H., Robinson, C.J., et al. 2009. Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl. Environ. Microbiol. 75, 7537\u20137541.","journal-title":"Appl. Environ. Microbiol."},{"key":"1271_CR48","doi-asserted-by":"publisher","first-page":"4371","DOI":"10.1128\/jb.173.14.4371-4378.1991","volume":"173","author":"TM Schmidt","year":"1991","unstructured":"Schmidt, T.M., DeLong, E.F., and Pace, N.R. 1991. Analysis of a marine picoplankton community by 16S rRNA gene cloning and sequencing. J. Bacteriol. 173, 4371\u20134378.","journal-title":"J. Bacteriol."},{"key":"1271_CR49","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.tibtech.2015.06.011","volume":"33","author":"NR Shin","year":"2015","unstructured":"Shin, N.R., Whon, T.W., and Bae, J.W. 2015. Proteobacteria: microbial signature of dysbiosis in gut microbiota. Trends Biotechnol. 33, 496\u2013503.","journal-title":"Trends Biotechnol."},{"key":"1271_CR50","unstructured":"Son, P. and Lewis, L. 2021. Hyperhomocysteinemia. StatPearls Publishing. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554408\/."},{"key":"1271_CR51","doi-asserted-by":"publisher","first-page":"2069","DOI":"10.1038\/ismej.2013.93","volume":"7","author":"JC Stegen","year":"2013","unstructured":"Stegen, J.C., Lin, X., Fredrickson, J.K., Chen, X., Kennedy, D.W., Murray, C.J., Rockhold, M.L., and Konopka, A. 2013. Quantifying community assembly processes and identifying features that impose them. ISME J. 7, 2069\u20132079.","journal-title":"ISME J."},{"key":"1271_CR52","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1038\/ismej.2012.22","volume":"6","author":"JC Stegen","year":"2012","unstructured":"Stegen, J.C., Lin, X., Konopka, A.E., and Fredrickson, J.K. 2012. Stochastic and deterministic assembly processes in subsurface microbial communities. ISME J. 6, 1653\u20131664.","journal-title":"ISME J."},{"key":"1271_CR53","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1016\/j.ijbiomac.2020.01.268","volume":"149","author":"A Tahmourespour","year":"2020","unstructured":"Tahmourespour, A., Ahmadi, A., and Fesharaki, M. 2020. The antitumor activity of exopolysaccharides from Pseudomonas strains against HT-29 colorectal cancer cell line. Int. J. Biol. Macromol. 149, 1072\u20131076.","journal-title":"Int. J. Biol. Macromol."},{"key":"1271_CR54","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/cmi.2010.67","volume":"8","author":"H Tlaskalov\u00e1-Hogenov\u00e1","year":"2011","unstructured":"Tlaskalov\u00e1-Hogenov\u00e1, H., \u0160t\u011bp\u00e1nkov\u00e1, R., Koz\u00e1kov\u00e1, H., Hudcovic, T., Vannucci, L., Tu\u010dkov\u00e1, L., Rossmann, P., Hrn\u010d\u00ed\u0159, T., Kverka, M., Z\u00e1kostelsk\u00e1, Z., et al. 2011. The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases. Cell. Mol. Immunol. 8, 110\u2013120.","journal-title":"Cell. Mol. Immunol."},{"key":"1271_CR55","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1128\/aem.63.2.767-770.1997","volume":"63","author":"K Ueno","year":"1997","unstructured":"Ueno, K. and Shetty, K. 1997. Effect of selected polysaccharideproducing soil bacteria on hyperhydricity control in oregano tissue cultures. Appl. Environ. Microbiol. 63, 767\u2013770.","journal-title":"Appl. Environ. Microbiol."},{"key":"1271_CR56","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1007\/s12020-014-0509-2","volume":"49","author":"C Virili","year":"2015","unstructured":"Virili, C., and Centanni, M. 2015. Does microbiota composition affect thyroid homeostasis? Endocrine 49, 583\u2013587.","journal-title":"Endocrine"},{"key":"1271_CR57","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.biopsych.2016.08.024","volume":"81","author":"HE Vuong","year":"2017","unstructured":"Vuong, H.E. and Hsiao, E.Y. 2017. Emerging roles for the gut microbiome in autism spectrum disorder. Biol. Psychiatry 81, 411\u2013423.","journal-title":"Biol. Psychiatry"},{"key":"1271_CR58","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1038\/ismej.2013.30","volume":"7","author":"J Wang","year":"2013","unstructured":"Wang, J., Shen, J., Wu, Y., Tu, C., Soininen, J., Stegen, J.C., He, J., Liu, X., Zhang, L., and Zhang, E. 2013. Phylogenetic beta diversity in bacterial assemblages across ecosystems: deterministic versus stochastic processes. ISME J. 7, 1310\u20131321.","journal-title":"ISME J."},{"key":"1271_CR59","doi-asserted-by":"publisher","first-page":"NP223","DOI":"10.1177\/1010539512436874","volume":"27","author":"Y Wang","year":"2015","unstructured":"Wang, Y. and Wang, W. 2015. Increasing incidence of thyroid cancer in Shanghai, China, 1983\u20132007. Asia Pac. J. Public Health 27, NP223\u2013NP229.","journal-title":"Asia Pac. J. Public Health"},{"key":"1271_CR60","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s40793-020-00358-7","volume":"15","author":"F Wemheuer","year":"2020","unstructured":"Wemheuer, F., Taylor, J.A., Daniel, R., Johnston, E., Meinicke, P., Thomas, T., and Wemheuer, B. 2020. Tax4Fun2: a R-based tool for the rapid prediction of habitat-specific functional profiles and functional redundancy based on 16S rRNA gene marker gene sequences. Environ. Microbiome 15, 11.","journal-title":"Environ. Microbiome"},{"key":"1271_CR61","doi-asserted-by":"publisher","first-page":"157","DOI":"10.2165\/11539770-000000000-00000","volume":"12","author":"DC Wu","year":"2011","unstructured":"Wu, D.C., Chan, W.W., Metelitsa, A.I., Fiorillo, L., and Lin, A.N. 2011. Pseudomonas skin infection: clinical features, epidemiology, and management. Am. J. Clin. Dermatol. 12, 157\u2013169.","journal-title":"Am. J. Clin. Dermatol."},{"key":"1271_CR62","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S0009-8981(02)00174-2","volume":"322","author":"LL Wu","year":"2002","unstructured":"Wu, L.L. and Wu, J.T. 2002. Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker. Clin. Chim. Acta 322, 21\u201328.","journal-title":"Clin. Chim. Acta"},{"key":"1271_CR63","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1038\/s41590-019-0451-9","volume":"20","author":"TP Wypych","year":"2019","unstructured":"Wypych, T.P., Wickramasinghe, L.C., and Marsland, B.J. 2019. The influence of the microbiome on respiratory health. Nat. Immunol. 20, 1279\u20131290.","journal-title":"Nat. Immunol."},{"key":"1271_CR64","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1186\/1471-2407-14-975","volume":"14","author":"SH Xie","year":"2014","unstructured":"Xie, S.H., Chen, J., Zhang, B., Wang, F., Li, S.S., Xie, C.H., Tse, L.A., and Cheng, J.Q. 2014. Time trends and age-period-cohort analyses on incidence rates of thyroid cancer in Shanghai and Hong Kong. BMC Cancer 14, 975.","journal-title":"BMC Cancer"},{"key":"1271_CR65","doi-asserted-by":"publisher","first-page":"16035","DOI":"10.1038\/sigtrans.2016.35","volume":"2","author":"S Xu","year":"2017","unstructured":"Xu, S., Liu, C.X., Xu, W., Huang, L., Zhao, J.Y., and Zhao, S.M. 2017. Butyrate induces apoptosis by activating PDC and inhibiting complex I through SIRT3 inactivation. Sig. Transduct. Target. Ther. 2, 16035.","journal-title":"Sig. Transduct. Target. Ther."},{"key":"1271_CR66","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/j.cell.2017.07.008","volume":"170","author":"T Yu","year":"2017","unstructured":"Yu, T., Guo, F., Yu, Y., Sun, T., Ma, D., Han, J., Qian, Y., Kryczek, I., Sun, D., Nagarsheth, N., et al. 2017. Fusobacterium nucleatum promotes chemoresistance to colorectal cancer by modulating autophagy. Cell 170, 548\u2013563.e16.","journal-title":"Cell"},{"key":"1271_CR67","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1007\/s12020-018-1831-x","volume":"64","author":"J Zhang","year":"2019","unstructured":"Zhang, J., Zhang, F., Zhao, C., Xu, Q., Liang, C., Yang, Y., Wang, H., Shang, Y., Wang, Y., Mu, X., et al. 2019. Dysbiosis of the gut microbiome is associated with thyroid cancer and thyroid nodules and correlated with clinical index of thyroid function. Endocrine 64, 564\u2013574.","journal-title":"Endocrine"},{"key":"1271_CR68","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1002\/(SICI)1097-0215(19960807)67:4<504::AID-IJC7>3.0.CO;2-W","volume":"67","author":"T Zheng","year":"1996","unstructured":"Zheng, T., Holford, T.R., Chen, Y., Ma, J.Z., Flannery, J., Liu, W., Russi, M., and Boyle, P. 1996. Time trend and age-period-cohort effect on incidence of thyroid cancer in Connecticut, 1935\u20131992. Int. J. Cancer 67, 504\u2013509.","journal-title":"Int. J. Cancer"},{"key":"1271_CR69","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1007\/s00284-014-0640-6","volume":"69","author":"L Zhou","year":"2014","unstructured":"Zhou, L., Li, X., Ahmed, A., Wu, D., Liu, L., Qiu, J., Yan, Y., Jin, M., and Xin, Y. 2014. Gut microbe analysis between hyperthyroid and healthy individuals. Curr. Microbiol. 69, 675\u2013680.","journal-title":"Curr. Microbiol."}],"container-title":["Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12275-021-1271-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12275-021-1271-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12275-021-1271-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T17:51:26Z","timestamp":1735062686000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12275-021-1271-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,6]]},"references-count":69,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["1271"],"URL":"https:\/\/doi.org\/10.1007\/s12275-021-1271-9","relation":{},"ISSN":["1225-8873","1976-3794"],"issn-type":[{"value":"1225-8873","type":"print"},{"value":"1976-3794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,6]]},"assertion":[{"value":"20 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 October 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}