{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:14:54Z","timestamp":1788830094632,"version":"build-2803163510"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T00:00:00Z","timestamp":1683936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T00:00:00Z","timestamp":1683936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"JSPS KAKENHI","award":["19K09065"],"award-info":[{"award-number":["19K09065"]}]},{"name":"JSPS KAKENHI","award":["19K07410"],"award-info":[{"award-number":["19K07410"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1007\/s12282-023-01467-0","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T07:48:29Z","timestamp":1684136909000},"page":"748-757","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Interleukin (IL)-17A in triple-negative breast cancer: a potent prognostic factor associated with intratumoral neutrophil infiltration"],"prefix":"10.1007","volume":"30","author":[{"given":"Freeha","family":"Khalid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5200-6514","authenticated-orcid":false,"given":"Kiyoshi","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mio","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fouzia","family":"Guestini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Miki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Miyashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Hirakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyo","family":"Ohi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuaki","family":"Sagara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironobu","family":"Sasano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,13]]},"reference":[{"key":"1467_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2021.188593","volume":"1876","author":"Y Zhu","year":"2021","unstructured":"Zhu Y, Zhu X, Tang C, Guan X, Zhang W. Progress and challenges of immunotherapy in triple-negative breast cancer. Biochim Biophys Acta Rev Cancer. 2021;1876: 188593. https:\/\/doi.org\/10.1016\/j.bbcan.2021.188593.","journal-title":"Biochim Biophys Acta Rev Cancer"},{"key":"1467_CR2","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1111\/j.1365-2567.2009.03240.x","volume":"129","author":"RM Onishi","year":"2010","unstructured":"Onishi RM, Gaffen SL. Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology. 2010;129:311\u201321. https:\/\/doi.org\/10.1111\/j.1365-2567.2009.03240.x.","journal-title":"Immunology"},{"key":"1467_CR3","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.lungcan.2009.11.013","volume":"69","author":"X Chen","year":"2010","unstructured":"Chen X, Wan J, Liu J, Xie W, Diao X, Xu J, et al. Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients. Lung Cancer. 2010;69:348\u201354. https:\/\/doi.org\/10.1016\/j.lungcan.2009.11.013.","journal-title":"Lung Cancer"},{"key":"1467_CR4","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.bbrc.2011.03.021","volume":"407","author":"J Liu","year":"2011","unstructured":"Liu J, Duan Y, Cheng X, Chen X, Xie W, Long H, et al. IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. Biochem Biophys Res Commun. 2011;407:348\u201354. https:\/\/doi.org\/10.1016\/j.bbrc.2011.03.021.","journal-title":"Biochem Biophys Res Commun"},{"key":"1467_CR5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0106834","volume":"9","author":"X Liu","year":"2014","unstructured":"Liu X, Jin H, Zhang G, Lin X, Chen C, Sun J, et al. Intratumor IL-17-positive mast cells are the major source of the IL-17 that is predictive of survival in gastric cancer patients. PLoS ONE. 2014;9: e106834. https:\/\/doi.org\/10.1371\/journal.pone.0106834.","journal-title":"PLoS ONE"},{"key":"1467_CR6","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1038\/onc.2013.537","volume":"34","author":"T Xiang","year":"2015","unstructured":"Xiang T, Long H, He L, Han X, Lin K, Liang Z, et al. Interleukin-17 produced by tumor microenvironment promotes self-renewal of CD133+ cancer stem-like cells in ovarian cancer. Oncogene. 2015;34:165\u201376. https:\/\/doi.org\/10.1038\/onc.2013.537.","journal-title":"Oncogene"},{"key":"1467_CR7","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/his.12156","volume":"63","author":"WC Chen","year":"2013","unstructured":"Chen WC, Lai YH, Chen HY, Guo HR, Su IJ, Chen HH. Interleukin-17-producing cell infiltration in the breast cancer tumour microenvironment is a poor prognostic factor. Histopathology. 2013;63:225\u201333. https:\/\/doi.org\/10.1111\/his.12156.","journal-title":"Histopathology"},{"key":"1467_CR8","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.cyto.2015.09.011","volume":"89","author":"X Qian","year":"2017","unstructured":"Qian X, Chen H, Wu X, Hu L, Huang Q, Jin Y. Interleukin-17 acts as double-edged sword in anti-tumor immunity and tumorigenesis. Cytokine. 2017;89:34\u201344. https:\/\/doi.org\/10.1016\/j.cyto.2015.09.011.","journal-title":"Cytokine"},{"key":"1467_CR9","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1038\/nrd3794","volume":"11","author":"P Miossec","year":"2012","unstructured":"Miossec P, Kolls JK. Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov. 2012;11:763\u201376. https:\/\/doi.org\/10.1038\/nrd3794.","journal-title":"Nat Rev Drug Discov"},{"key":"1467_CR10","doi-asserted-by":"publisher","first-page":"2689","DOI":"10.22034\/APJCP.2017.18.10.2689","volume":"18","author":"E Soto-Perez-de-Celis","year":"2017","unstructured":"Soto-Perez-de-Celis E, Chavarri-Guerra Y, Leon-Rodriguez E, Gamboa-Dominguez A. Tumor-associated neutrophils in breast cancer subtypes. Asian Pac J Cancer Prev. 2017;18:2689\u201393. https:\/\/doi.org\/10.22034\/APJCP.2017.18.10.2689.","journal-title":"Asian Pac J Cancer Prev"},{"key":"1467_CR11","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.3390\/ijms22041918","volume":"22","author":"M Yamaguchi","year":"2021","unstructured":"Yamaguchi M, Takagi K, Narita K, Miki Y, Onodera Y, Miyashita M, et al. Stromal CCL5 promotes breast cancer progression by interacting with CCR3 in tumor cells. Int J Mol Sci. 2021;22:1918. https:\/\/doi.org\/10.3390\/ijms22041918.","journal-title":"Int J Mol Sci"},{"key":"1467_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.582863","volume":"10","author":"C Shuai","year":"2020","unstructured":"Shuai C, Yang X, Pan H, Han W. Estrogen receptor downregulates expression of PD-1\/PD-L1 and infiltration of CD8+ T cells by inhibiting IL-17 signaling transduction in breast cancer. Front Oncol. 2020;10: 582863. https:\/\/doi.org\/10.3389\/fonc.2020.582863.","journal-title":"Front Oncol"},{"key":"1467_CR13","doi-asserted-by":"publisher","first-page":"2506","DOI":"10.1245\/s10434-012-2268-8","volume":"19","author":"FM Gu","year":"2012","unstructured":"Gu FM, Gao Q, Shi GM, Zhang X, Wang J, Jiang JH, et al. Intratumoral IL-17+ cells and neutrophils show strong prognostic significance in intrahepatic cholangiocarcinoma. Ann Surg Oncol. 2012;19:2506\u201314. https:\/\/doi.org\/10.1245\/s10434-012-2268-8.","journal-title":"Ann Surg Oncol"},{"key":"1467_CR14","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s13046-018-1003-0","volume":"38","author":"S Li","year":"2019","unstructured":"Li S, Cong X, Gao H, Lan X, Li Z, Wang W, et al. Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells. J Exp Clin Cancer Res. 2019;38:6. https:\/\/doi.org\/10.1186\/s13046-018-1003-0.","journal-title":"J Exp Clin Cancer Res"},{"key":"1467_CR15","doi-asserted-by":"publisher","first-page":"2400","DOI":"10.2741\/2853","volume":"13","author":"Y Kobayashi","year":"2008","unstructured":"Kobayashi Y. The role of chemokines in neutrophil biology. Front Biosci. 2008;13:2400\u20137. https:\/\/doi.org\/10.2741\/2853.","journal-title":"Front Biosci"},{"key":"1467_CR16","doi-asserted-by":"publisher","first-page":"2887","DOI":"10.1158\/1078-0432.CCR-18-3684","volume":"25","author":"R Ogawa","year":"2019","unstructured":"Ogawa R, Yamamoto T, Hirai H, Hanada K, Kiyasu Y, Nishikawa G, et al. Loss of SMAD4 promotes colorectal cancer progression by recruiting tumor-associated neutrophils via the CXCL1\/8-CXCR2 axis. Clin Cancer Res. 2019;25:2887\u201399. https:\/\/doi.org\/10.1158\/1078-0432.CCR-18-3684.","journal-title":"Clin Cancer Res"},{"key":"1467_CR17","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.cell.2012.04.042","volume":"150","author":"S Acharyya","year":"2012","unstructured":"Acharyya S, Oskarsson T, Vanharanta S, Malladi S, Kim J, Morris PG, et al. A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell. 2012;150:165\u201378. https:\/\/doi.org\/10.1016\/j.cell.2012.04.042.","journal-title":"Cell"},{"key":"1467_CR18","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.intimp.2018.01.026","volume":"56","author":"K Ma","year":"2018","unstructured":"Ma K, Yang L, Shen R, Kong B, Chen W, Liang J, et al. Th17 cells regulate the production of CXCL1 in breast cancer. Int Immunopharmacol. 2018;56:320\u20139. https:\/\/doi.org\/10.1016\/j.intimp.2018.01.026.","journal-title":"Int Immunopharmacol"},{"key":"1467_CR19","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.4049\/jimmunol.0902423","volume":"184","author":"S Datta","year":"2010","unstructured":"Datta S, Novotny M, Pavicic PG Jr, Zhao C, Herjan T, Hartupee J, et al. IL-17 regulates CXCL1 mRNA stability via an AUUUA\/tristetraprolin-independent sequence. J Immunol. 2010;184:1484\u201391. https:\/\/doi.org\/10.4049\/jimmunol.0902423.","journal-title":"J Immunol"},{"key":"1467_CR20","doi-asserted-by":"publisher","first-page":"6177","DOI":"10.4049\/jimmunol.175.9.6177","volume":"175","author":"M Numasaki","year":"2005","unstructured":"Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol. 2005;175:6177\u201389. https:\/\/doi.org\/10.4049\/jimmunol.175.9.6177.","journal-title":"J Immunol"},{"key":"1467_CR21","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.3892\/mmr.2019.10310","volume":"20","author":"L Liu","year":"2019","unstructured":"Liu L, Sun H, Wu S, Tan H, Sun Y, Liu X, et al. IL-17A promotes CXCR2-dependent angiogenesis in a mouse model of liver cancer. Mol Med Rep. 2019;20:1065\u201374. https:\/\/doi.org\/10.3892\/mmr.2019.10310.","journal-title":"Mol Med Rep"},{"key":"1467_CR22","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.659996","volume":"12","author":"S SenGupta","year":"2021","unstructured":"SenGupta S, Hein LE, Xu Y, Zhang J, Konwerski JR, Li Y, et al. Triple-negative breast cancer cells recruit neutrophils by secreting TGF-\u03b2 and CXCR2 ligands. Front Immunol. 2021;12: 659996. https:\/\/doi.org\/10.3389\/fimmu.2021.659996.","journal-title":"Front Immunol"},{"key":"1467_CR23","doi-asserted-by":"publisher","first-page":"8060","DOI":"10.1038\/s41598-020-64950-0","volume":"10","author":"JH Chiu","year":"2020","unstructured":"Chiu JH, Tseng LM, Huang TT, Liu CY, Wang JY, Huang CP, et al. MEGF11 is related to tumour recurrence in triple negative breast cancer via chemokine upregulation. Sci Rep. 2020;10:8060. https:\/\/doi.org\/10.1038\/s41598-020-64950-0.","journal-title":"Sci Rep"},{"key":"1467_CR24","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1186\/1476-4598-10-150","volume":"10","author":"FM Gu","year":"2011","unstructured":"Gu FM, Li QL, Gao Q, Jiang JH, Zhu K, Huang XY, et al. IL-17 induces AKT-dependent IL-6\/JAK2\/STAT3 activation and tumor progression in hepatocellular carcinoma. Mol Cancer. 2011;10:150. https:\/\/doi.org\/10.1186\/1476-4598-10-150.","journal-title":"Mol Cancer"},{"key":"1467_CR25","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.3892\/etm.2021.10726","volume":"22","author":"Y Bai","year":"2021","unstructured":"Bai Y, Li H, Lv R. Interleukin-17 activates JAK2\/STAT3, PI3K\/Akt and nuclear factor-\u03baB signaling pathway to promote the tumorigenesis of cervical cancer. Exp Ther Med. 2021;22:1291. https:\/\/doi.org\/10.3892\/etm.2021.10726.","journal-title":"Exp Ther Med"},{"key":"1467_CR26","doi-asserted-by":"publisher","first-page":"3788","DOI":"10.1158\/0008-5472.CAN-15-0054","volume":"75","author":"L Benevides","year":"2015","unstructured":"Benevides L, da Fonseca DM, Donate PB, Tiezzi DG, De Carvalho DD, de Andrade JM, et al. IL17 promotes mammary tumor progression by changing the behavior of tumor cells and eliciting tumorigenic neutrophils recruitment. Cancer Res. 2015;75:3788\u201399. https:\/\/doi.org\/10.1158\/0008-5472.CAN-15-0054.","journal-title":"Cancer Res"},{"key":"1467_CR27","doi-asserted-by":"publisher","first-page":"2339","DOI":"10.1007\/s00262-021-02867-x","volume":"70","author":"YF Tsai","year":"2021","unstructured":"Tsai YF, Huang CC, Lin YS, Hsu CY, Huang CP, Liu CY, et al. Interleukin 17A promotes cell migration, enhances anoikis resistance, and creates a microenvironment suitable for triple negative breast cancer tumor metastasis. Cancer Immunol Immunother. 2021;70:2339\u201351. https:\/\/doi.org\/10.1007\/s00262-021-02867-x.","journal-title":"Cancer Immunol Immunother"},{"key":"1467_CR28","doi-asserted-by":"publisher","DOI":"10.4161\/2162402X.2014.984539","volume":"4","author":"S Punt","year":"2015","unstructured":"Punt S, Fleuren GJ, Kritikou E, Lubberts E, Trimbos JB, Jordanova ES, et al. Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer. Oncoimmunology. 2015;4: e984539. https:\/\/doi.org\/10.4161\/2162402X.2014.984539.","journal-title":"Oncoimmunology"},{"key":"1467_CR29","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1007\/s10549-020-05540-6","volume":"180","author":"XL Qian","year":"2020","unstructured":"Qian XL, Xu P, Zhang YQ, Song YM, Li YQ, Li WD, et al. Increased number of intratumoral IL-17+ cells, a harbinger of the adverse prognosis of triple-negative breast cancer. Breast Cancer Res Treat. 2020;180:311\u20139. https:\/\/doi.org\/10.1007\/s10549-020-05540-6.","journal-title":"Breast Cancer Res Treat"},{"key":"1467_CR30","doi-asserted-by":"publisher","first-page":"2400","DOI":"10.4049\/jimmunol.1600138","volume":"197","author":"R Liu","year":"2016","unstructured":"Liu R, Lauridsen HM, Amezquita RA, Pierce RW, Jane-Wit D, Fang C, et al. IL-17 promotes neutrophil-mediated immunity by activating microvascular pericytes and not endothelium. J Immunol. 2016;197:2400\u20138. https:\/\/doi.org\/10.4049\/jimmunol.1600138.","journal-title":"J Immunol"},{"key":"1467_CR31","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1038\/s41571-019-0222-4","volume":"16","author":"ME Shaul","year":"2019","unstructured":"Shaul ME, Fridlender ZG. Tumour-associated neutrophils in patients with cancer. Nat Rev Clin Oncol. 2019;16:601\u201320. https:\/\/doi.org\/10.1038\/s41571-019-0222-4.","journal-title":"Nat Rev Clin Oncol"},{"key":"1467_CR32","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/s0091-6749(00)90189-1","volume":"105","author":"H Hoshino","year":"2000","unstructured":"Hoshino H, Laan M, Sj\u00f6strand M, L\u00f6tvall J, Skoogh BE, Linden A. Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo. J Allergy Clin Immunol. 2000;105:143\u20139. https:\/\/doi.org\/10.1016\/s0091-6749(00)90189-1.","journal-title":"J Allergy Clin Immunol"},{"key":"1467_CR33","doi-asserted-by":"publisher","first-page":"2328","DOI":"10.3390\/cancers13102328","volume":"13","author":"F Boissi\u00e8re-Michot","year":"2021","unstructured":"Boissi\u00e8re-Michot F, Jacot W, Massol O, Mollevi C, Lazennec G. CXCR2 levels correlate with immune infiltration and a better prognosis of triple-negative breast cancers. Cancers (Basel). 2021;13:2328. https:\/\/doi.org\/10.3390\/cancers13102328.","journal-title":"Cancers (Basel)"},{"key":"1467_CR34","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1158\/1078-0432.CCR-18-2544","volume":"25","author":"Y Wang","year":"2019","unstructured":"Wang Y, Chen J, Yang L, Li J, Wu W, Huang M, et al. Tumor-contacted neutrophils promote metastasis by a CD90-TIMP-1 juxtacrine-paracrine loop. Clin Cancer Res. 2019;25:1957\u201369. https:\/\/doi.org\/10.1158\/1078-0432.CCR-18-2544.","journal-title":"Clin Cancer Res"},{"key":"1467_CR35","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s12885-021-07789-6","volume":"21","author":"SK Geng","year":"2021","unstructured":"Geng SK, Fu SM, Ma SH, Fu YP, Zhang HW. Tumor infiltrating neutrophil might play a major role in predicting the clinical outcome of breast cancer patients treated with neoadjuvant chemotherapy. BMC Cancer. 2021;21:68. https:\/\/doi.org\/10.1186\/s12885-021-07789-6.","journal-title":"BMC Cancer"},{"key":"1467_CR36","doi-asserted-by":"publisher","first-page":"6996","DOI":"10.1080\/21655979.2021.1977102","volume":"12","author":"LB Kwantwi","year":"2021","unstructured":"Kwantwi LB, Wang S, Zhang W, Peng W, Cai Z, Sheng Y, et al. Tumor-associated neutrophils activated by tumor-derived CCL20 (C-C motif chemokine ligand 20) promote T cell immunosuppression via programmed death-ligand 1 (PD-L1) in breast cancer. Bioengineered. 2021;12:6996\u20137006. https:\/\/doi.org\/10.1080\/21655979.2021.1977102.","journal-title":"Bioengineered"},{"key":"1467_CR37","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1186\/s13058-019-1237-6","volume":"21","author":"HT Snoderly","year":"2019","unstructured":"Snoderly HT, Boone BA, Bennewitz MF. Neutrophil extracellular traps in breast cancer and beyond: current perspectives on NET stimuli, thrombosis and metastasis, and clinical utility for diagnosis and treatment. Breast Cancer Res. 2019;21:145. https:\/\/doi.org\/10.1186\/s13058-019-1237-6.","journal-title":"Breast Cancer Res"},{"key":"1467_CR38","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2021-004210","volume":"10","author":"Y Zhang","year":"2022","unstructured":"Zhang Y, Guo L, Dai Q, Shang B, Xiao T, Di X, Zhang K, Feng L, Shou J, Wang Y. A signature for pan-cancer prognosis based on neutrophil extracellular traps. J Immunother Cancer. 2022;10: e004210. https:\/\/doi.org\/10.1136\/jitc-2021-004210.","journal-title":"J Immunother Cancer"},{"key":"1467_CR39","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20190354","volume":"217","author":"Y Zhang","year":"2020","unstructured":"Zhang Y, Chandra V, Riquelme Sanchez E, Dutta P, Quesada PR, Rakoski A, et al. Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer. J Exp Med. 2020;217: e20190354. https:\/\/doi.org\/10.1084\/jem.20190354.","journal-title":"J Exp Med"}],"container-title":["Breast Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12282-023-01467-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12282-023-01467-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12282-023-01467-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T10:06:14Z","timestamp":1691229974000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12282-023-01467-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,13]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["1467"],"URL":"https:\/\/doi.org\/10.1007\/s12282-023-01467-0","relation":{},"ISSN":["1340-6868","1880-4233"],"issn-type":[{"value":"1340-6868","type":"print"},{"value":"1880-4233","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,13]]},"assertion":[{"value":"23 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflict of interest in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Statement of human rights: all procedures performed in studies involving human participants were in accordance with the ethical standards of the Ethics Committee at an individual institution (Tohoku University Graduate School of Medicine, Tohoku Kosai Hospital, and Sagara Hospital) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The design of the present study is a retrospective study and informed consent is not required. This article does not contain any animal studies.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human participants and\/or animals"}},{"value":"Informed consent is not obtained because the design of the present study is a retrospective study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}