{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T21:14:16Z","timestamp":1773695656851,"version":"3.50.1"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004077","name":"Kocaeli \u00dcniversitesi","doi-asserted-by":"publisher","award":["2559"],"award-info":[{"award-number":["2559"]}],"id":[{"id":"10.13039\/501100004077","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Hematol Blood Transfus"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s12288-022-01574-6","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T20:35:25Z","timestamp":1666038925000},"page":"220-227","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of AGEs, sRAGE and HMGB1 on Clinical Outcomes in Multiple Myeloma"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9556-8915","authenticated-orcid":false,"given":"Ayfer","family":"Geduk\u00b9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2907-5108","authenticated-orcid":false,"given":"Berrin","family":"Oztas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6349-9839","authenticated-orcid":false,"given":"Baldan Huri","family":"Ery\u0131lmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7083-9379","authenticated-orcid":false,"given":"Esra Terzi","family":"Demirsoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4303-9488","authenticated-orcid":false,"given":"Meral U.","family":"Menguc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8513-8476","authenticated-orcid":false,"given":"Serkan","family":"Unal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7588-6000","authenticated-orcid":false,"given":"Sinan","family":"Mersin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9797-3922","authenticated-orcid":false,"given":"Merve Gokcen","family":"Polat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6033-5150","authenticated-orcid":false,"given":"Kemal","family":"Aygun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2422-8646","authenticated-orcid":false,"given":"Emel Merve","family":"Yenihayat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4160-1139","authenticated-orcid":false,"given":"Hayrunnisa","family":"Albayrak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6372-6306","authenticated-orcid":false,"given":"Hasim Atakan","family":"Erol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5875-7546","authenticated-orcid":false,"given":"Sibel","family":"Balc\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5603-1178","authenticated-orcid":false,"given":"Ozgur","family":"Mehtap\u00b9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0851-3583","authenticated-orcid":false,"given":"Pinar","family":"Tarkun\u00b9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5164-6301","authenticated-orcid":false,"given":"Abdullah","family":"Hacihanefioglu\u00b9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"1574_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-019-00499-w","author":"LI Plotkin","year":"2019","unstructured":"Plotkin LI, Essex AL, Davis HM (2019) RAGE Signaling in Skeletal Biology. Curr Osteoporos Rep. https:\/\/doi.org\/10.1007\/s11914-019-00499-w","journal-title":"Curr Osteoporos Rep"},{"key":"1574_CR2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/6809703","author":"AM Kay","year":"2016","unstructured":"Kay AM, Simpson CL (2016) The Role of AGE\/RAGE Signaling in Diabetes-Mediated Vascular Calcification. J Diabetes Res. https:\/\/doi.org\/10.1155\/2016\/6809703. Stewart JA Jr.","journal-title":"J Diabetes Res"},{"key":"1574_CR3","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-020-03928-y","author":"BN Waghela","year":"2021","unstructured":"Waghela BN, Vaidya FU, Ranjan K, Chhipa AS, Tiwari BS, Pathak C (2021) AGE-RAGE synergy influences programmed cell death signaling to promote cancer. Mol Cell Biochem. https:\/\/doi.org\/10.1007\/s11010-020-03928-y","journal-title":"Mol Cell Biochem"},{"key":"1574_CR4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b00058","author":"S Bongarzone","year":"2017","unstructured":"Bongarzone S, Savickas V, Luzi F, Gee AD (2017) Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective. J Med Chem. https:\/\/doi.org\/10.1021\/acs.jmedchem.7b00058","journal-title":"J Med Chem"},{"key":"1574_CR5","first-page":"1203","volume":"30","author":"E Galliera","year":"2016","unstructured":"Galliera E, Marazzi MG, Vianello E, Drago L, Luzzati A, Bendinelli P, Maroni P, Tacchini L, Desiderio MA, Corsi Romanelli MM (2016) Circulating sRAGE in the diagnosis of osteolytic bone metastasis. J Biol Regul Homeost Agents 30:1203\u20131208","journal-title":"J Biol Regul Homeost Agents"},{"key":"1574_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/s0167-4889(00)00087-2","author":"AM Schmidt","year":"2000","unstructured":"Schmidt AM, Yan SD, Yan SF, Stern DM (2000) The biology of the receptor for advanced glycation end products and its ligands. Biochim Biophys Acta. https:\/\/doi.org\/10.1016\/s0167-4889(00)00087-2","journal-title":"Biochim Biophys Acta"},{"key":"1574_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2020.07.003","author":"B Dariya","year":"2020","unstructured":"Dariya B, Nagaraju GP (2020) Advanced glycation end products in diabetes, cancer and phytochemical therapy. Drug Discov Today. https:\/\/doi.org\/10.1016\/j.drudis.2020.07.003","journal-title":"Drug Discov Today"},{"key":"1574_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acr.2016.08.001","author":"DP Turner","year":"2017","unstructured":"Turner DP (2017) The Role of Advanced Glycation End-Products in Cancer Disparity. Adv Cancer Res. https:\/\/doi.org\/10.1016\/bs.acr.2016.08.001","journal-title":"Adv Cancer Res"},{"key":"1574_CR9","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-020-00920-3","author":"S Yuan","year":"2020","unstructured":"Yuan S, Liu Z, Xu Z, Liu J, Zhang J (2020) High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignancies. J Hematol Oncol. https:\/\/doi.org\/10.1186\/s13045-020-00920-3","journal-title":"J Hematol Oncol"},{"key":"1574_CR10","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1900860","author":"H Zhong","year":"2020","unstructured":"Zhong H, Li X, Zhou S, Jiang P, Liu X, Ouyang M, Nie Y, Chen X, Zhang L, Liu Y, Tao T, Tang J (2020) Interplay between RAGE and TLR4 Regulates HMGB1-Induced Inflammation by Promoting Cell Surface Expression of RAGE and TLR4. J Immunol. https:\/\/doi.org\/10.4049\/jimmunol.1900860","journal-title":"J Immunol"},{"key":"1574_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2009.11.001","author":"ZG Luan","year":"2010","unstructured":"Luan ZG, Zhang H, Yang PT, Ma XC, Zhang C, Guo RX (2010) HMGB1 activates nuclear factor-\u03baB signaling by RAGE and increases the production of TNF-\u03b1 in human umbilical vein endothelial cells. Immunobiology. https:\/\/doi.org\/10.1016\/j.imbio.2009.11.001","journal-title":"Immunobiology"},{"key":"1574_CR12","doi-asserted-by":"publisher","DOI":"10.1007\/s13277-015-3940-y","author":"A Rojas","year":"2016","unstructured":"Rojas A, Delgado-L\u00f3pez F, Perez-Castro R, Gonzalez I, Romero J, Rojas I, Araya P, A\u00f1azco C, Morales E, Llanos J (2016) HMGB1 enhances the protumoral activities of M2 macrophages by a RAGE-dependent mechanism. Tumour Biol. https:\/\/doi.org\/10.1007\/s13277-015-3940-y","journal-title":"Tumour Biol"},{"key":"1574_CR13","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxs051","author":"CA Wild","year":"2012","unstructured":"Wild CA, Bergmann C, Fritz G, Schuler P, Hoffmann TK, Lotfi R, Westendorf A, Brandau S, Lang S (2012) HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cells. Int Immunol. https:\/\/doi.org\/10.1093\/intimm\/dxs051","journal-title":"Int Immunol"},{"key":"1574_CR14","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-2347","author":"KH Parker","year":"2014","unstructured":"Parker KH, Sinha P, Horn LA, Clements VK, Yang H, Li J, Tracey KJ, Ostrand-Rosenberg S (2014) HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res. https:\/\/doi.org\/10.1158\/0008-5472.CAN-13-2347","journal-title":"Cancer Res"},{"key":"1574_CR15","first-page":"445","volume":"10","author":"H Kuniyasu","year":"2003","unstructured":"Kuniyasu H, Chihara Y, Takahashi T (2003) Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer. Oncol Rep 10:445\u2013448","journal-title":"Oncol Rep"},{"key":"1574_CR16","first-page":"4805","volume":"62","author":"HJ Huttunen","year":"2002","unstructured":"Huttunen HJ, Fages C, Kuja-Panula J, Ridley AJ, Rauvala H (2002) Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis. Cancer Res 62:4805\u20134811","journal-title":"Cancer Res"},{"key":"1574_CR17","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgh333","author":"B Bartling","year":"2005","unstructured":"Bartling B, Hofmann HS, Weigle B, Silber RE, Simm A (2005) Down-regulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma. Carcinogenesis. https:\/\/doi.org\/10.1093\/carcin\/bgh333","journal-title":"Carcinogenesis"},{"key":"1574_CR18","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M509436200","author":"F Riuzzi","year":"2006","unstructured":"Riuzzi F, Sorci G, Donato R (2006) The amphoterin (HMGB1)\/receptor for advanced glycation end products (RAGE) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. Functional inactivation of RAGE in L6 myoblasts results in tumor formation in vivo. J Biol Chem. https:\/\/doi.org\/10.1074\/jbc.M509436200","journal-title":"J Biol Chem"},{"key":"1574_CR19","doi-asserted-by":"publisher","unstructured":"Greenlee RT, Murray T, Bolden S, Wingo PA, Cancer statistics (2000) CA Cancer J Clin. 2000; https:\/\/doi.org\/10.3322\/canjclin.50.1.7","DOI":"10.3322\/canjclin.50.1.7"},{"key":"1574_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2015.04.004","author":"S Yang","year":"2015","unstructured":"Yang S, Pinney SM, Mallick P, Ho SM, Bracken B, Wu T (2015) Impact of Oxidative Stress Biomarkers and Carboxymethyllysine (an Advanced Glycation End Product) on Prostate Cancer: A Prospective Study. Clin Genitourin Cancer. https:\/\/doi.org\/10.1016\/j.clgc.2015.04.004","journal-title":"Clin Genitourin Cancer"},{"key":"1574_CR21","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-19-0457","author":"OO Omofuma","year":"2020","unstructured":"Omofuma OO, Turner DP, Peterson LL, Merchant AT, Zhang J, Steck SE (2020) Dietary Advanced Glycation End-products (AGE) and Risk of Breast Cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO). Cancer Prev Res (Phila). https:\/\/doi.org\/10.1158\/1940-6207.CAPR-19-0457","journal-title":"Cancer Prev Res (Phila)"},{"key":"1574_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2012.02.039","author":"AM Korwar","year":"2012","unstructured":"Korwar AM, Bhonsle HS, Chougale AD, Kote SS, Gawai KR, Ghole VS, Koppikar CB, Kulkarni MJ (2012) Analysis of AGE modified proteins and RAGE expression in HER2\/neu negative invasive ductal carcinoma. Biochem Biophys Res Commun. https:\/\/doi.org\/10.1016\/j.bbrc.2012.02.039","journal-title":"Biochem Biophys Res Commun"},{"key":"1574_CR23","doi-asserted-by":"publisher","DOI":"10.1002\/path.5072","author":"S Menini","year":"2018","unstructured":"Menini S, Iacobini C (2018) The advanced glycation end-product N\u03f5-carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention. J Pathol. https:\/\/doi.org\/10.1002\/path.5072. de Latouliere LManni I, Ionta V, Blasetti Fantauzzi C, Pesce C, Cappello P, Novelli F, Piaggio G, Pugliese G","journal-title":"J Pathol"},{"key":"1574_CR24","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-012-0498-7","author":"S Gangemi","year":"2012","unstructured":"Gangemi S, Allegra A, Alonci A, Cristani M, Russo S, Speciale A, Penna G, Spatari G, Cannav\u00f2 A, Bellomo G, Musolino C (2012) Increase of novel biomarkers for oxidative stress in patients with plasma cell disorders and in multiple myeloma patients with bone lesions. Inflamm Res. https:\/\/doi.org\/10.1007\/s00011-012-0498-7","journal-title":"Inflamm Res"},{"key":"1574_CR25","doi-asserted-by":"publisher","DOI":"10.3390\/antiox8030055","author":"A Allegra","year":"2019","unstructured":"Allegra A, Musolino C, Pace E, Innao V (2019) Evaluation of the AGE\/sRAGE Axis in Patients with Multiple Myeloma. Antioxid (Basel). https:\/\/doi.org\/10.3390\/antiox8030055. Di Salvo EFerraro M, Casciaro M, Spatari G, Tartarisco G, Allegra AG, Gangemi S","journal-title":"Antioxid (Basel)"},{"key":"1574_CR26","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2017.1344845","author":"J Katz","year":"2017","unstructured":"Katz J, Moreb J, Baitinger C, Singer C, Caudle RM (2017) Advanced glycation endproducts (AGEs) in saliva of patients with multiple myeloma - a pilot study. Leuk Lymphoma. https:\/\/doi.org\/10.1080\/10428194.2017.1344845","journal-title":"Leuk Lymphoma"},{"key":"1574_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2011.04.009","author":"XN Dong","year":"2011","unstructured":"Dong XN, Qin A, Xu J, Wang X (2011) In situ accumulation of advanced glycation endproducts (AGEs) in bone matrix and its correlation with osteoclastic bone resorption. Bone. https:\/\/doi.org\/10.1016\/j.bone.2011.04.009","journal-title":"Bone"},{"key":"1574_CR28","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M610536200","author":"U Valcourt","year":"2007","unstructured":"Valcourt U, Merle B, Gineyts E, Viguet-Carrin S, Delmas PD, Garnero P (2007) Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation. J Biol Chem. https:\/\/doi.org\/10.1074\/jbc.M610536200","journal-title":"J Biol Chem"},{"key":"1574_CR29","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00309.2015","author":"Z Li","year":"2016","unstructured":"Li Z, Li C, Zhou Y, Chen W, Luo G, Zhang Z, Wang H, Zhang Y, Xu D, Sheng P (2016) Advanced glycation end products biphasically modulate bone resorption in osteoclast-like cells. Am J Physiol Endocrinol Metab. https:\/\/doi.org\/10.1152\/ajpendo.00309.2015","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"1574_CR30","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.669499","author":"HZ Meng","year":"2015","unstructured":"Meng HZ, Zhang WL, Liu F, Yang MW (2015) J Biol Chem. https:\/\/doi.org\/10.1074\/jbc.M115.669499. Advanced Glycation End Products Affect Osteoblast Proliferation and Function by Modulating Autophagy Via the Receptor of Advanced Glycation End Products\/RafProtein\/Mitogen-activated Protein Kinase\/Extracellular Signal-regulated Kinase Kinase\/Extracellular Signal-regulated Kinase (RAGE\/Raf\/MEK\/ERK) Pathway"},{"key":"1574_CR31","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.14086","author":"A Allegra","year":"2020","unstructured":"Allegra A, Pace E, Tartarisco G, Innao V (2020) Changes in Serum Interleukin-8 and sRAGE Levels in Multiple Myeloma Patients. Anticancer Res. https:\/\/doi.org\/10.21873\/anticanres.14086. DI Salvo EAllegra AG, Ferraro M, Musolino C, Gangemi S","journal-title":"Anticancer Res"},{"key":"1574_CR32","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-20-0855","author":"EK Aglago","year":"2021","unstructured":"Aglago EK, Rinaldi S, Freisling H, Jiao L, Hughes DJ, Fedirko V, Schalkwijk CG, Weiderpass E, Dahm CC, Overvad K, Eriksen AK, Kyr\u00f8 C, Boutron-Ruault MC, Rothwell JA, Severi G, Katzke V, K\u00fchn T, Schulze MB, Aleksandrova K, Masala G, Krogh V, Panico S, Tumino R, Naccarati A, Bueno-de-Mesquita B (2021) Soluble Receptor for Advanced Glycation End-products (sRAGE) and Colorectal Cancer Risk: A Case-Control Study Nested within a European Prospective Cohort. Cancer Epidemiol Biomarkers Prev. https:\/\/doi.org\/10.1158\/1055-9965.EPI-20-0855. van Gils CHSandanger TM, Gram IT, Skeie G, Quir\u00f3s JR, Jakszyn P, S\u00e1nchez MJ, Amiano P, Huerta JM, Ardanaz E, Johansson I, Harlid S, Perez-Cornago A, May\u00e9n AL, Cordova R, Gunter MJ, Vineis P, Cross AJ, Riboli E, Jenab M","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"1574_CR33","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2573","author":"L Jiao","year":"2011","unstructured":"Jiao L, Weinstein SJ, Albanes D, Taylor PR, Graubard BI, Virtamo J, Stolzenberg-Solomon RZ (2011) Evidence that serum levels of the soluble receptor for advanced glycation end products are inversely associated with pancreatic cancer risk: a prospective study. Cancer Res. https:\/\/doi.org\/10.1158\/0008-5472.CAN-10-2573","journal-title":"Cancer Res"},{"key":"1574_CR34","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26264","author":"KA Moy","year":"2013","unstructured":"Moy KA, Jiao L, Freedman ND, Weinstein SJ, Sinha R, Virtamo J, Albanes D, Stolzenberg-Solomon RZ (2013) Soluble receptor for advanced glycation end products and risk of liver cancer. Hepatology. https:\/\/doi.org\/10.1002\/hep.26264","journal-title":"Hepatology"},{"key":"1574_CR35","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.1AB0120-212RR","author":"MM Corsi Romanelli","year":"2020","unstructured":"Corsi Romanelli MM, Banfi G (2020) Longitudinal evaluation of Wnt inhibitors and comparison with others serum osteoimmunological biomarkers in osteolytic bone metastasis. J Leukoc Biol. https:\/\/doi.org\/10.1002\/JLB.1AB0120-212RR. de Toma DLonghi E","journal-title":"J Leukoc Biol"},{"key":"1574_CR36","doi-asserted-by":"publisher","DOI":"10.2147\/JBM.S147743","author":"S Nomura","year":"2018","unstructured":"Nomura S, Ito T, Yoshimura H, Hotta M, Nakanishi T, Fujita S, Nakaya A, Satake A, Ishii K (2018) Evaluation of thrombosis-related biomarkers before and after therapy in patients with multiple myeloma. J Blood Med. https:\/\/doi.org\/10.2147\/JBM.S147743","journal-title":"J Blood Med"},{"key":"1574_CR37","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-021-02387-9","author":"W Lai","year":"2021","unstructured":"Lai W, Li X, Kong Q, Chen H, Li Y, Xu LH, Fang J (2021) Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells. Cancer Cell Int. https:\/\/doi.org\/10.1186\/s12935-021-02387-9","journal-title":"Cancer Cell Int"},{"key":"1574_CR38","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.10137","author":"J Ning","year":"2021","unstructured":"Ning J, Yang R, Wang H, Cui L (2021) HMGB1 enhances chemotherapy resistance in multiple myeloma cells by activating the nuclear factor-\u03baB pathway. Exp Ther Med. https:\/\/doi.org\/10.3892\/etm.2021.10137","journal-title":"Exp Ther Med"},{"key":"1574_CR39","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201900288R","author":"JJ Lee","year":"2019","unstructured":"Lee JJ, Park IH, Rhee WJ, Kim HS, Shin JS (2019) HMGB1 modulates the balance between senescence and apoptosis in response to genotoxic stress. FASEB J. https:\/\/doi.org\/10.1096\/fj.201900288R","journal-title":"FASEB J"},{"key":"1574_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2012.10.021","author":"G Sorci","year":"2013","unstructured":"Sorci G, Riuzzi F, Giambanco I, Donato R (2013) RAGE in tissue homeostasis, repair and regeneration. Biochim Biophys Acta. https:\/\/doi.org\/10.1016\/j.bbamcr.2012.10.021","journal-title":"Biochim Biophys Acta"},{"key":"1574_CR41","doi-asserted-by":"publisher","DOI":"10.1038\/nm1622","author":"L Apetoh","year":"2007","unstructured":"Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A, Mignot G, Maiuri MC, Ullrich E, Saulnier P, Yang H, Amigorena S, Ryffel B, Barrat FJ, Saftig P, Levi F, Lidereau R, Nogues C, Mira JP, Chompret A, Joulin V, Clavel-Chapelon F, Bourhis J, Andr\u00e9 F, Delaloge S, Tursz T, Kroemer G, Zitvogel L (2007) Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med. https:\/\/doi.org\/10.1038\/nm1622","journal-title":"Nat Med"}],"updated-by":[{"DOI":"10.1007\/s12288-023-01626-5","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T00:00:00Z","timestamp":1674000000000}}],"container-title":["Indian Journal of Hematology and Blood Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12288-022-01574-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12288-022-01574-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12288-022-01574-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T06:36:03Z","timestamp":1680244563000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12288-022-01574-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,17]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["1574"],"URL":"https:\/\/doi.org\/10.1007\/s12288-022-01574-6","relation":{"references":[{"id-type":"uri","id":"","asserted-by":"subject"}],"correction":[{"id-type":"doi","id":"10.1007\/s12288-023-01626-5","asserted-by":"object"}]},"ISSN":["0971-4502","0974-0449"],"issn-type":[{"value":"0971-4502","type":"print"},{"value":"0974-0449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,17]]},"assertion":[{"value":"26 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2023","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s12288-023-01626-5","URL":"https:\/\/doi.org\/10.1007\/s12288-023-01626-5","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declared no potential conflicts of interest with respect to the research, authorship, and\/or publication of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This study was supported by Kocaeli University Scientific Research Projects Coordination Unit. Project Number: 2559.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Financial Disclosure"}},{"value":"The study protocol was approved by the Kocaeli Faculty of Medicine Research Ethical Committee. (Project number: 2021\/81, project approval no: GOKAEK-2021\/5.12, approval date: 04\/03\/2021).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Written consent was obtained from all participants.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Written consent was obtained from all participants.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}