{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:42:28Z","timestamp":1791996148561,"version":"4.4.0"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ind J Clin Biochem"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s12291-023-01127-2","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T07:09:58Z","timestamp":1680505798000},"page":"179-187","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Long Term Treatment of Corticostreroids May Cause Hepatotoxicity and Oxidative Damage: A Case Controlled Study"],"prefix":"10.1007","volume":"39","author":[{"given":"Priyanka","family":"Tiwari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitika","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7835-9406","authenticated-orcid":false,"given":"Bechan","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,1]]},"reference":[{"issue":"5","key":"1127_CR1","first-page":"643","volume":"28","author":"A Iagnocco","year":"2010","unstructured":"Iagnocco A, Meenagh G, Riente L, Filippucci E, et al. Ultrasound imaging for the rheumatologist XXIX. Sonographic assessment of the knee in patients with osteoarthritis. Clin Exp Rheumatol. 2010;28(5):643\u20136.","journal-title":"Clin Exp Rheumatol"},{"issue":"2","key":"1127_CR2","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/S0033-8389(22)00370-0","volume":"32","author":"RK Chhem","year":"1994","unstructured":"Chhem RK, Kaplan PA, Dussault RG. Ultrasonography of musculoskeletal system. Radiol Clin North Am. 1994;32(2):275\u2013893.","journal-title":"Radiol Clin North Am"},{"issue":"1","key":"1127_CR3","doi-asserted-by":"publisher","first-page":"e000536","DOI":"10.1136\/rmdopen-2017-000536","volume":"6","author":"C Hua","year":"2020","unstructured":"Hua C, Buttgereit F, Combe B. Glucocorticoids in rheumatoid arthritis: current status and future studies. RMD Open. 2020;6(1):e000536. https:\/\/doi.org\/10.1136\/rmdopen-2017-000536.","journal-title":"RMD Open"},{"key":"1127_CR4","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1155\/2016\/5356307","volume":"10","author":"G Sun","year":"2016","unstructured":"Sun G, Hazlewood G, Bernatsky S, Kaplan GG, Eksteen B, Barnabe C. Association between air pollution and the development of rheumatic disease: a systematic review. Int J Rheumatol. 2016;10:53\u20136. https:\/\/doi.org\/10.1155\/2016\/5356307.","journal-title":"Int J Rheumatol"},{"issue":"1","key":"1127_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.steroids.2006.10.007","volume":"72","author":"AM Sadowska","year":"2007","unstructured":"Sadowska AM, Klebe B, Germonpr\u00e9 P, De Backer WA. Glucocorticoids as antioxidants in treatment of asthma and COPD. New application for an old medication? Steroids. 2007;72(1):1\u20136. https:\/\/doi.org\/10.1016\/j.steroids.2006.10.007.","journal-title":"Steroids"},{"issue":"4","key":"1127_CR6","first-page":"426","volume":"55","author":"RA Jessar","year":"1955","unstructured":"Jessar RA, Hollander JL. Types of arthritis and their medical treatment. Am J Nurs. 1955;55(4):426\u20139.","journal-title":"Am J Nurs"},{"issue":"5","key":"1127_CR7","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1007\/s00296-020-04731-0","volume":"41","author":"K Almutairi","year":"2021","unstructured":"Almutairi K, Nossent J, Preen D, Keen H, Inderjeeth C. The global prevalence of rheumatoid arthritis: a meta-analysis based on a systematic review. Rheumatol Int. 2021;41(5):863\u201377. https:\/\/doi.org\/10.1007\/s00296-020-04731-0.","journal-title":"Rheumatol Int"},{"issue":"8","key":"1127_CR8","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1002\/art.39161","volume":"67","author":"R Tsuda","year":"2015","unstructured":"Tsuda R, Ozawa T, Kobayashi E. Monoclonal antibody against citrullinated peptides obtained from rheumatoid arthritis patients reacts with numerous citrullinated microbial and food proteins. Arthritis Rheumatol. 2015;67(8):2020\u201331. https:\/\/doi.org\/10.1002\/art.39161.","journal-title":"Arthritis Rheumatol"},{"issue":"5","key":"1127_CR9","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.4049\/jimmunol.1600145","volume":"98","author":"T Gong","year":"2017","unstructured":"Gong T, Wang X, Yang Y. Plant lectins activate the NLRP3 inflammasome to promote inflammatory disorders. J Immunol. 2017;98(5):2082\u201392. https:\/\/doi.org\/10.4049\/jimmunol.1600145.","journal-title":"J Immunol"},{"issue":"3","key":"1127_CR10","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/nutd.016.7","volume":"6","author":"LR De Christopher","year":"2016","unstructured":"De Christopher LR, Uribarri J, Tucker KL. Intake of high-fructose corn syrup sweetened soft drinks, fruit drinks and apple juice is associated with prevalent arthritis in US adults, aged 20\u201330years. Nutr Diabetes. 2016;6(3):199. https:\/\/doi.org\/10.1038\/nutd.016.7.","journal-title":"Nutr Diabetes"},{"key":"1127_CR11","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1007\/s10067-015-2881-6","volume":"34","author":"JF Solus","year":"2015","unstructured":"Solus JF, Chung CP, Oeser A, Li C, Rho YH, Bradley KM, Kawai VK, Smith JR, Stein CM. Genetics of serum concentration of IL-6 and TNF\u03b1 in systemic lupus erythematosus rheumatoid arthritis: a candidate gene analysis. Clin Rheumatol. 2015;34:1375\u201382.","journal-title":"Clin Rheumatol"},{"key":"1127_CR12","unstructured":"The nobel prize in physiology and medicine 1950. Nobelprize.org. http:\/\/www.nobelprize.org\/nobel_prizes\/medicine\/laureates\/1950\/hench"},{"key":"1127_CR13","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1177\/014107689809101004","volume":"91","author":"J Glyn","year":"1998","unstructured":"Glyn J. The discovery and early use of cortisone. J R Soc Med. 1998;91:513\u20137.","journal-title":"J R Soc Med"},{"key":"1127_CR14","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1056\/NEJMra050541","volume":"353","author":"T Rhen","year":"2005","unstructured":"Rhen T, Cidlowski J. Anti-inflammatory action of glucocorticoids new mechanisms for old drugs. N Engl J Med. 2005;353:1711\u201323.","journal-title":"N Engl J Med"},{"key":"1127_CR15","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.jsbmb.2010.03.058","volume":"120","author":"U Baschant","year":"2010","unstructured":"Baschant U, Tuckermann J. The role of the glucocorticoid receptor in inflammation and immunity. J Steroid Biochem Mol Biol. 2010;120:69\u201375.","journal-title":"J Steroid Biochem Mol Biol"},{"key":"1127_CR16","first-page":"133","volume":"195","author":"RF Beers","year":"1952","unstructured":"Beers RF, SizerI W. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Chem. 1952;195:133\u201340.","journal-title":"J Chem"},{"issue":"8","key":"1127_CR17","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1111\/j.1756-185X.2011.01630.x","volume":"41","author":"L Monteser\u00edn","year":"2018","unstructured":"Monteser\u00edn L, Jim\u00e9nez M, Linares P, Rodr\u00edguez-Mart\u00edn L, \u00c1lvarez-Cuenllas B, \u00c1lvarez-Ca\u00f1as C, Jorquera CF. Acute hepatitis secondary to high-dose intravenous methylprednisolone. Gastroenterol Hepatol. 2018;41(8):508\u20139. https:\/\/doi.org\/10.1111\/j.1756-185X.2011.01630.x.","journal-title":"Gastroenterol Hepatol"},{"key":"1127_CR18","first-page":"1","volume":"25","author":"VK Gupta","year":"2019","unstructured":"Gupta VK, Siddiqi NJ, Ojha AK, Sharma B. Hepatoprotective effect of Aloevera against cartap and malathion induced toxicity in Wistar rats. J Cell Physiol. 2019;25:1\u201315.","journal-title":"J Cell Physiol"},{"key":"1127_CR19","first-page":"2","volume":"335","author":"EC Agnes","year":"2009","unstructured":"Agnes EC, Karen EC. The anti-inflammatory and immunosuppressive effects of Glucocorticoids, recent developments and mechanistic insights. Mol Cell Endocrinol. 2009;335:2\u201335.","journal-title":"Mol Cell Endocrinol"},{"key":"1127_CR20","doi-asserted-by":"crossref","unstructured":"Qui\u00f1onez-Flores CM, Gonz\u00e1lez-Ch\u00e1vez SA, Del R\u00edoN\u00e1jera D, Pacheco-Tena C. oxidative stress relevance in the pathogenesis of the rheumatoid arthritis: a systematic review. Biomed Res Int. 2016;1\u201314.","DOI":"10.1155\/2016\/6097417"},{"issue":"1\u20132","key":"1127_CR21","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s002960050097","volume":"19","author":"HS Ozt\u00fcrk","year":"1999","unstructured":"Ozt\u00fcrk HS, Cimen MY, Cimen OB, Ka\u00e7maz M, Durak I. Oxidant\/antioxidant status of plasma samples from patients with rheumatoid arthritis. Rheumatol Int. 1999;19(1\u20132):35\u20137. https:\/\/doi.org\/10.1007\/s002960050097.","journal-title":"Rheumatol Int"},{"issue":"4","key":"1127_CR22","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1136\/archdischild-2015-309522)","volume":"10","author":"F Aljebab","year":"2016","unstructured":"Aljebab F, Choonara I, Conroy S. Systematic review of the toxicity of short-course oral corticosteroids in children. Arch Dis Child. 2016;10(4):365\u201370. https:\/\/doi.org\/10.1136\/archdischild-2015-309522).","journal-title":"Arch Dis Child"},{"issue":"3","key":"1127_CR23","first-page":"356","volume":"2","author":"R Reu\u00df","year":"2007","unstructured":"Reu\u00df R, Retzlaff K, Vogel S, Franke FE, Oschmann P. Autoimmune hepatitis after high-dose intravenous methylprednisolone pulse in RR-MS. CEJ Med. 2007;2(3):356\u20139.","journal-title":"CEJ Med"},{"key":"1127_CR24","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","volume":"47","author":"S Marklund","year":"1974","unstructured":"Marklund S, Marklund G. Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974;47:67\u2013474.","journal-title":"Eur J Biochem"},{"key":"1127_CR25","unstructured":"NICE. Corticosteroids-oral. https:\/\/cks.nice.org.uk\/corticosteroidsoral. Accessed Apr 2017"},{"issue":"6","key":"1127_CR26","first-page":"415","volume":"24","author":"S Itoh","year":"1977","unstructured":"Itoh S, Igarashi M, Tsukada Y, Ichinoe A. Non alcoholic fatty liver with alcoholichyaline after long-term glucocorticoid therapy. Acta Hepato-Gastroenterol. 1977;24(6):415\u20138.","journal-title":"Acta Hepato-Gastroenterol"},{"issue":"3","key":"1127_CR27","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.cca.2016.10.007","volume":"46","author":"S Mateen","year":"2016","unstructured":"Mateen S, Moin S, Zafar A, Khan AQ. Redox signaling in rheumatoid arthritis and the preventive role of polyphenols. Clin Chim Acta. 2016;46(3):4\u201310.","journal-title":"Clin Chim Acta"},{"key":"1127_CR28","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1186\/ar1447","volume":"6","author":"CA Hitchon","year":"2004","unstructured":"Hitchon CA, El-Gabalawy HS. Oxidation in rheumatoid arthritis. Arthritis Res Ther. 2004;6:265\u201378.","journal-title":"Arthritis Res Ther"},{"issue":"7","key":"1127_CR29","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s00011-005-1355-8)","volume":"54","author":"S Herman","year":"2005","unstructured":"Herman S, Zurgil N. Deutsch M Low dose methotrexate induces apoptosis with Reactive oxygen species involve mentin T lymphocytic cell lines to a greater extent than in monocytic lines. Inflamm Res. 2005;54(7):273\u201380. https:\/\/doi.org\/10.1007\/s00011-005-1355-8).","journal-title":"Inflamm Res"},{"issue":"23","key":"1127_CR30","first-page":"4985","volume":"20","author":"M Suntiparpluacha","year":"2016","unstructured":"Suntiparpluacha M, Tammachote N, Tammachote R. Triamcinolone acetonide reducesviability, induces oxidative stress, and alters gene expressions of human chondrocytes. Eur Rev Med Pharmacol Sci. 2016;20(23):4985\u201392.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"1127_CR31","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/978-3-0348-7720-6_22","volume":"17","author":"MW Whitehouse","year":"1985","unstructured":"Whitehouse MW, Cleland LG. Reactive oxygen species and drug therapy for inflammatory diseases. Agents Act Suppl. 1985;17:177\u2013218. https:\/\/doi.org\/10.1007\/978-3-0348-7720-6_22.","journal-title":"Agents Act Suppl"},{"issue":"5","key":"1127_CR32","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1136\/ard.42.5.558","volume":"42","author":"AA Youssef","year":"1983","unstructured":"Youssef AA, Baron DN. Leucocyte superoxide dismutase in rheumatoid arthritis. Rheum Dis. 1983;42(5):558\u201362.","journal-title":"Rheum Dis"},{"key":"1127_CR33","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"192","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosebrough NJ, Farr AL, Reandel RJ. Protein measurement with folin phenol reagent. J Biol Chem. 1951;192:265\u201375.","journal-title":"J Biol Chem"},{"key":"1127_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/bmjoq-2017-000209","volume":"6","author":"L Mundell","year":"2017","unstructured":"Mundell L, Lindemann R, Douglas J. Monitoring long-termoral corticosteroids. BMJ Open Quality. 2017;6:1\u20139.","journal-title":"BMJ Open Quality"},{"key":"1127_CR35","unstructured":"Bethesda (MD): National institute of diabetes and digestive and kidney diseases. 2012. Clinical and Research Information on Drug Induced Liver Injury [Internet]."},{"issue":"32","key":"1127_CR36","doi-asserted-by":"publisher","first-page":"30208","DOI":"10.1074\/jbc.M103604200","volume":"276","author":"K Ito","year":"2001","unstructured":"Ito K, Jazrawi E, Cosio B, Barnes PJ, Adcock IM. p 65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex. J Biol Chem. 2001;276(32):30208\u201315. https:\/\/doi.org\/10.1074\/jbc.M103604200.","journal-title":"J Biol Chem"},{"issue":"10","key":"1127_CR37","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.1345\/aph.1H171","volume":"40","author":"F Topal","year":"2006","unstructured":"Topal F, Ozaslan E, Akbulut S, Kucukazman M, Yuksel O, Altiparmak E. Methylprednisolone-induced toxic hepatitis. Ann Pharmacother. 2006;40(10):1868\u201371.","journal-title":"Ann Pharmacother"},{"issue":"6","key":"1127_CR38","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1089\/thy.2000.10.521","volume":"10","author":"M Weissel","year":"2000","unstructured":"Weissel M, Hauff W. Fatal liver failure after high-dose glucocorticoid pulse therapy in a patient with severe thyroid eye disease. Thyroid. 2000;10(6):521.","journal-title":"Thyroid"},{"issue":"8","key":"1127_CR39","doi-asserted-by":"publisher","first-page":"656","DOI":"10.5812\/kowsar.1735143X.713","volume":"11","author":"K Gutkowski","year":"2011","unstructured":"Gutkowski K, Chwist A, Hartleb M. Liver injury induced by high-dose methylprednisolone therapy: a case report and brief review of the literature. Hepat Mon. 2011;11(8):656\u201361. https:\/\/doi.org\/10.5812\/kowsar.1735143X.713.","journal-title":"Hepat Mon"},{"issue":"6","key":"1127_CR40","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1080\/030097498442271","volume":"27","author":"A Kiziltunc","year":"1998","unstructured":"Kiziltunc A, Co\u011falgil S, Cerraho\u011flu L. Carnitine and antioxidants levels in patients with rheumatoid arthritis. Scand J Rheumatol. 1998;27(6):441\u20135. https:\/\/doi.org\/10.1080\/030097498442271.","journal-title":"Scand J Rheumatol"},{"issue":"4","key":"1127_CR41","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1007\/pl00011172)","volume":"19","author":"MY Cimen","year":"2000","unstructured":"Cimen MY, Cimen OB, Ka\u00e7maz M, Ozt\u00fcrk HS, Yorgancio\u011flu R, Durak I. Oxidant\/antioxidant status of theery throcytes from patients with rheumatoid arthritis. Clin Rheumatol. 2000;19(4):275\u20137. https:\/\/doi.org\/10.1007\/pl00011172).","journal-title":"Clin Rheumatol"},{"key":"1127_CR42","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1007\/s00296-005-0079-y","volume":"26","author":"S Ozgocmen","year":"2006","unstructured":"Ozgocmen S, Ozyurt H, Sogut S, et al. Antioxidant status, lipid peroxidation and nitric oxide in fibromyalgia: etiologic and therapeutic concerns. Rheumatol Int. 2006;26:598\u2013603. https:\/\/doi.org\/10.1007\/s00296-005-0079-y.","journal-title":"Rheumatol Int"},{"issue":"5","key":"1127_CR43","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1007\/s00296-001-0163-x","volume":"21","author":"S Taysi","year":"2002","unstructured":"Taysi S, Polat F, Gul M, Sari RA, Bakan E. Lipid peroxidation, some extracellular antioxidants, and antioxidant enzymes in serum of patients with rheumatoid arthritis. Rheumatol Int. 2002;21(5):200\u20134. https:\/\/doi.org\/10.1007\/s00296-001-0163-x.","journal-title":"Rheumatol Int"},{"key":"1127_CR44","first-page":"178","volume":"118","author":"F Karatas","year":"2003","unstructured":"Karatas F, Ozates I, Canatan H, Halifeoglu I. Antioxidant status & lipid peroxidation in patients with rheumatoid arthritis. Indian J Med Res. 2003;118:178\u201381.","journal-title":"Indian J Med Res"},{"issue":"1","key":"1127_CR45","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1002\/cbf.1055","volume":"22","author":"A Kamanli","year":"2004","unstructured":"Kamanli A, Naziro\u011flu M, Aydilek N, Hacievliyagil C. Plasma lipid peroxidation and Antioxidant levels in patients with rheumatoid arthritis. Cell Biochem Funct. 2004;22(1):53\u20137. https:\/\/doi.org\/10.1002\/cbf.1055.","journal-title":"Cell Biochem Funct"},{"issue":"11","key":"1127_CR46","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1016\/j.clinbiochem.2005.08.003","volume":"38","author":"S Sarban","year":"2005","unstructured":"Sarban S, Kocyigit A, Yazar M, Isikan UE. Plasma total antioxidant capacity, lipid peroxidation, anderythrocyte antioxidant enzyme activities in patients with rheumatoid arthritis and osteoarthritis. Clin Biochem. 2005;38(11):981\u20136.","journal-title":"Clin Biochem"},{"issue":"3\u20134","key":"1127_CR47","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.clinbiochem.2006.10.006","volume":"40","author":"O Altindag","year":"2007","unstructured":"Altindag O, Karakoc M, Kocyigit A, Celik H, Soran N. Increased DNA damageand Oxidative stress in patients with rheumatoid arthritis. Clin Biochem. 2007;40(3\u20134):167\u201371. https:\/\/doi.org\/10.1016\/j.clinbiochem.2006.10.006.","journal-title":"Clin Biochem"},{"issue":"1","key":"1127_CR48","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1007\/s10067-006-0244-z","volume":"26","author":"Y Ozkan","year":"2007","unstructured":"Ozkan Y, Yard\u00fdm-Akayd\u00fdn S, Sepici A, Keskin E, Sepici V, Simsek B. Oxidative status in rheumatoid arthritis. Clin Rheumatol. 2007;26(1):64\u20138. https:\/\/doi.org\/10.1007\/s10067-006-0244-z.","journal-title":"Clin Rheumatol"},{"issue":"1","key":"1127_CR49","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/j.1756-185X.2009.01375.x","volume":"12","author":"P Vasanthi","year":"2009","unstructured":"Vasanthi P, Nalini G, Rajasekhar G. Status of oxidative stress in rheumatoid arthritis. Int J Rheum Dis. 2009;12(1):29\u201333. https:\/\/doi.org\/10.1111\/j.1756-185X.2009.01375.x.","journal-title":"Int J Rheum Dis"},{"issue":"6","key":"1127_CR50","first-page":"353","volume":"47","author":"S Tetik","year":"2010","unstructured":"Tetik S, Ahmad S, Alturfan AA, Fresko I, Disbudak M, Sahin Y, et al. Determination of oxidant stress in plasma of rheumatoid arthritis and primary osteoarthritis patients. Indian J Biochem Biophys. 2010;47(6):353\u20138.","journal-title":"Indian J Biochem Biophys"},{"issue":"1","key":"1127_CR51","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1038\/nrrheum.2010.96","volume":"7","author":"M Kapoor","year":"2011","unstructured":"Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol. 2011;7(1):33\u201342. https:\/\/doi.org\/10.1038\/nrrheum.2010.96.","journal-title":"Nat Rev Rheumatol"},{"issue":"9783","key":"1127_CR52","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.1016\/S0140-6736(11)60243-2","volume":"377","author":"JW Bijlsma","year":"2011","unstructured":"Bijlsma JW, Berenbaum F, Lafeber FP. Osteoarthritis: an update with relevance for clinical practice. Lancet. 2011;377(9783):2115\u201326. https:\/\/doi.org\/10.1016\/S0140-6736(11)60243-2.","journal-title":"Lancet"},{"key":"1127_CR53","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-1-4939-2895-8_1","volume":"872","author":"DK Granner","year":"2015","unstructured":"Granner DK, Wang JC, Yamamoto KR. Regulatory actions of glucocorticoid hormones: from organisms to mechanisms. Adv Exp Med Biol. 2015;872:3\u201331. https:\/\/doi.org\/10.1007\/978-1-4939-2895-8_1.","journal-title":"Adv Exp Med Biol"},{"key":"1127_CR54","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.ijpharm.2020.119912","volume":"59","author":"F Laffleur","year":"2020","unstructured":"Laffleur F, Keckeis V. Advances in drug delivery systems: work in progresss till needed? Int J Pharm. 2020;59:199\u2013221. https:\/\/doi.org\/10.1016\/j.ijpharm.2020.119912.","journal-title":"Int J Pharm"},{"key":"1127_CR55","doi-asserted-by":"publisher","first-page":"104516","DOI":"10.1016\/j.archoralbio.2019.104516","volume":"107","author":"MG Piancino","year":"2019","unstructured":"Piancino MG, Tortarolo A, Polimeni A, Cannavale R, Tonni I, Deregibus A. Adverse effects of the bite-raised condition in animal studies: a systematic review. Arch Oral Biol. 2019;107:104516. https:\/\/doi.org\/10.1016\/j.archoralbio.2019.104516.","journal-title":"Arch Oral Biol"},{"issue":"2","key":"1127_CR56","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/0002-9343(94)90131-7","volume":"96","author":"K Saag","year":"1994","unstructured":"Saag K, Koehnke R, Caldwell J, Brasington R, Burmeister L, Zimmerman B, Kohler J, Furst D. Lowdoselong-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious advers events. Am J Med. 1994;96(2):115\u201323.","journal-title":"Am J Med"},{"issue":"10","key":"1127_CR57","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.1345\/aph.1H171","volume":"40","author":"F Topal","year":"2006","unstructured":"Topal F, \u00d6zaslan E, Akbulut S, K\u00fc\u00e7\u00fckazman M, Y\u00fcksel O, Alt\u0131parmak E. Methylprednisolone-induced toxic hepatitis. Ann Pharmacother. 2006;40(10):1868\u201371.","journal-title":"Ann Pharmacother"},{"issue":"4","key":"1127_CR58","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.bbadis.2016.01.003)","volume":"1862","author":"P Lepetsos","year":"2016","unstructured":"Lepetsos P, Papavassiliou AG. ROS\/oxidative stress signaling in osteoarthritis. Biochim Biophys Acta. 2016;1862(4):576\u201391. https:\/\/doi.org\/10.1016\/j.bbadis.2016.01.003).","journal-title":"Biochim Biophys Acta"},{"issue":"4","key":"1127_CR59","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1111\/j.1756-185X.2011.01630.x","volume":"14","author":"SZ Hassan","year":"2011","unstructured":"Hassan SZ, Gheita TA, Kenawy SA, Fahim AT, El-Sorougy IM, Manal S. Oxidative Stress in systemic lupus erythematosus and rheumatoid arthritis patients: relationship to disease manifestations andactivity. Int J Rheum Dis. 2011;14(4):325\u201331. https:\/\/doi.org\/10.1111\/j.1756-185X.2011.01630.x.","journal-title":"Int J Rheum Dis"},{"key":"1127_CR60","unstructured":"Shen L, Zhang H, Zhou, Liu R. Association between polymorphisms of interleukin 12"},{"issue":"1","key":"1127_CR61","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1186\/s12931-021-01833-6","volume":"22","author":"M Ghanei","year":"2021","unstructured":"Ghanei M, Solaymani-Dodaran M, Qazvini A, et al. The efficacy of corticosteroids therapy in patients with moderate to severe SARS-CoV-2 infection: a multicenter, randomized, open-label trial. Respir Res. 2021;22(1):245. https:\/\/doi.org\/10.1186\/s12931-021-01833-6.","journal-title":"Respir Res"}],"container-title":["Indian Journal of Clinical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12291-023-01127-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12291-023-01127-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12291-023-01127-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T15:52:29Z","timestamp":1744213949000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12291-023-01127-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,1]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["1127"],"URL":"https:\/\/doi.org\/10.1007\/s12291-023-01127-2","relation":{},"ISSN":["0970-1915","0974-0422"],"issn-type":[{"value":"0970-1915","type":"print"},{"value":"0974-0422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,1]]},"assertion":[{"value":"23 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 February 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Corresponding author on behalf of all authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Vide office no. IERB\/2016\/03 by institute of ethics committee of population resource and research centre Allahabad.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Consent was taken from the patients.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Consent was obtained from the patients for publication of this case.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}