{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:33:28Z","timestamp":1792690408070,"version":"4.5.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T00:00:00Z","timestamp":1552003200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Musculoskelet Surg"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s12306-019-00595-1","type":"journal-article","created":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T03:16:45Z","timestamp":1552015005000},"page":"59-65","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Failure rates and functional results for intercalary femur reconstructions after tumour resection"],"prefix":"10.1007","volume":"104","author":[{"given":"J. I.","family":"Albergo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. C.","family":"Gaston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. L.","family":"Farfalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Laitinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Parry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Ayerza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Risk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. M.","family":"Jeys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. A.","family":"Aponte-Tinao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,3,8]]},"reference":[{"issue":"2","key":"595_CR1","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s11999-015-4588-z","volume":"474","author":"J Benevenia","year":"2016","unstructured":"Benevenia J, Kirchner R, Patterson F, Beebe K, Wirtz DC, Rivero S, Palma M, Friedrich MJ (2016) Outcomes of a modular intercalary endoprosthesis as treatment for segmental defects of the femur, tibia, and humerus. Clin Orthop Relat Res 474(2):539\u2013548","journal-title":"Clin Orthop Relat Res"},{"issue":"6","key":"595_CR2","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.2106\/JBJS.F.01324","volume":"90","author":"LM Jeys","year":"2008","unstructured":"Jeys LM, Kulkarni A, Grimer RJ, Carter SR, Tillman RM, Abudu A (2008) Endoprosthetic reconstruction for the treatment of musculoskeletal tumors of the appendicular skeleton and pelvis. J Bone Jt Surg Am 90(6):1265\u20131271","journal-title":"J Bone Jt Surg Am"},{"issue":"50","key":"595_CR3","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1002\/1097-0142(19820815)50:4<613::AID-CNCR2820500402>3.0.CO;2-L","volume":"15","author":"HJ Mankin","year":"1982","unstructured":"Mankin HJ, Doppelt SH, Sullivan TR, Tomford WW (1982) Osteoarticular and intercalary allograft transplantation in the management of malignant tumors of bone. Cancer 15(50):613\u2013630","journal-title":"Cancer"},{"key":"595_CR4","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1302\/0301-620X.78B4.0780652","volume":"78","author":"A Abudu","year":"1996","unstructured":"Abudu A, Carter SR, Grimer RJ (1996) The outcome and functional results of diaphyseal endoprostheses after tumour excision. J Bone Jt Surg Br 78:652\u2013657","journal-title":"J Bone Jt Surg Br"},{"issue":"3","key":"595_CR5","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1007\/s11999-011-1952-5","volume":"470","author":"L Aponte-Tinao","year":"2012","unstructured":"Aponte-Tinao L, Farfalli GL, Ritacco LE, Ayerza MA, Muscolo DL (2012) Intercalary femur allografts are an acceptable alternative after tumor resection. Clin Orthop Relat Res 470(3):728\u2013734","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"595_CR6","first-page":"81","volume":"78","author":"D Donati","year":"1993","unstructured":"Donati D, Capanna R, Campanacci D, Del Ben M, Ercolani C, Masetti C, Taminiau A, Exner GU, Dubousset JF, Paitout D et al (1993) The use of massive bone allografts for intercalary reconstruction and arthrodeses after tumor resection. A multicentric European study. Chir Organi Mov 78(2):81\u201394","journal-title":"Chir Organi Mov"},{"key":"595_CR7","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1097\/01.blo.0000141652.93178.10","volume":"426","author":"DL Muscolo","year":"2004","unstructured":"Muscolo DL, Ayerza MA, Aponte-Tinao L, Ranalletta M, Abalo E (2004) Intercalary femur and tibia segmental allografts provide an acceptable alternative in reconstructing tumor resections. Clin Orthop Relat Res 426:97\u2013102","journal-title":"Clin Orthop Relat Res"},{"key":"595_CR8","doi-asserted-by":"publisher","first-page":"97","DOI":"10.2106\/00004623-199701000-00010","volume":"79","author":"EJ Ortiz-Cruz","year":"1997","unstructured":"Ortiz-Cruz EJ, Gebhardt MC, Jennings LC, Springfield DS, Mankin HJ (1997) The results of transplantation of intercalary allografts after resection of tumors: a long-term follow-up study. J Bone Jt Surg Am 79:97\u2013106","journal-title":"J Bone Jt Surg Am"},{"key":"595_CR9","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1055\/s-2001-16597","volume":"33","author":"M Ceruso","year":"2001","unstructured":"Ceruso M, Falcone C, Innocenti M, Delcroix L, Capanna R, Manfrini M (2001) Skeletal reconstruction with a free vascularized fibula graft associated to bone allograft after resection of malignant bone tumor of limbs. Handchir Mikrochir Plast Chir 33:277\u2013282","journal-title":"Handchir Mikrochir Plast Chir"},{"key":"595_CR10","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.1097\/01.prs.0000189203.38204.d5","volume":"116","author":"DW Chang","year":"2005","unstructured":"Chang DW, Weber KL (2005) Use of a vascularized fibula bone flap and intercalary allograft for diaphyseal reconstruction after resection of primary extremity bone sarcomas. Plast Reconstr Surg 116:1918\u20131925","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"595_CR11","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1302\/0301-620X.89B3.18508","volume":"89","author":"AH Krieg","year":"2007","unstructured":"Krieg AH, Davidson AW, Stalley PD (2007) Intercalary femoral reconstruction with extracorporeal irradiated autogenous bone graft in limb-salvage surgery. J Bone Jt Surg Br 89(3):366\u2013371","journal-title":"J Bone Jt Surg Br"},{"issue":"4","key":"595_CR12","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s00264-012-1715-2","volume":"37","author":"T Nakamura","year":"2013","unstructured":"Nakamura T, Abudu A, Grimer RJ, Carter SR, Jeys L, Tillman RM (2013) The clinical outcomes of extracorporeal irradiated and re-implanted cemented autologous bone graft of femoral diaphysis after tumour resection. Int Orthop 37(4):647\u2013651","journal-title":"Int Orthop"},{"key":"595_CR13","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1302\/0301-620X.76B1.8300655","volume":"76","author":"J Ca\u00f1adell","year":"1994","unstructured":"Ca\u00f1adell J, Forriol F, Cara JA (1994) Removal of metaphyseal bone tumours with preservation of the epiphysis: physeal distraction before excision. J Bone Jt Surg Br 76:127\u2013132","journal-title":"J Bone Jt Surg Br"},{"key":"595_CR14","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1302\/0301-620X.79B3.0790403","volume":"79","author":"H Tsuchiya","year":"1997","unstructured":"Tsuchiya H, Tomita K, Minematsu K, Mori Y, Asada N, Kitano S (1997) Limb salvage using distraction osteogenesis: a classification of the technique. J Bone Jt Surg Br 79:403\u2013411","journal-title":"J Bone Jt Surg Br"},{"issue":"4","key":"595_CR15","doi-asserted-by":"publisher","first-page":"e26","DOI":"10.2106\/JBJS.M.00655","volume":"96","author":"MP Bus","year":"2014","unstructured":"Bus MP, Dijkstra PD, van de Sande MA, Taminiau AH, Schreuder HW, Jutte PC, van der Geest IC, Schaap GR, Bramer JA (2014) Intercalary allograft reconstructions following resection of primary bone tumors: a nationwide multicenter study. J Bone Jt Surg Am 96(4):e26. https:\/\/doi.org\/10.2106\/JBJS.M.00655","journal-title":"J Bone Jt Surg Am"},{"issue":"1","key":"595_CR16","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s00264-004-0614-6","volume":"29","author":"E Aldlyami","year":"2005","unstructured":"Aldlyami E, Abudu A, Grimer RJ, Carter SR, Tillman RM (2005) Endoprosthetic replacement of diaphyseal bone defects. Long-term results. Int Orthop 29(1):25\u201329","journal-title":"Int Orthop"},{"issue":"3","key":"595_CR17","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1007\/s11999-014-3659-x","volume":"473","author":"LA Aponte-Tinao","year":"2015","unstructured":"Aponte-Tinao LA, Ayerza MA, Muscolo DL, Farfalli GL (2015) Should fractures in massive intercalary bone allografts of the lower limb be treated with ORIF or with a new allograft? Clin Orthop Relat Res 473(3):805\u2013811","journal-title":"Clin Orthop Relat Res"},{"issue":"6","key":"595_CR18","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1302\/0301-620X.94B6.28680","volume":"94","author":"T Frisoni","year":"2012","unstructured":"Frisoni T, Cevolani L, Giorgini A, Dozza B, Donati DM (2012) Factors affecting outcome of massive intercalary bone allografts in the treatment of tumours of the femur. J Bone Jt Surg Br 94(6):836\u2013841","journal-title":"J Bone Jt Surg Br"},{"key":"595_CR19","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.2106\/00004623-199311000-00011","volume":"75","author":"RC Thompson","year":"1993","unstructured":"Thompson RC, Pickvance EA, Garry D (1993) Fractures in large segment allografts. J Bone Jt Surg Am 75:1663\u20131673","journal-title":"J Bone Jt Surg Am"},{"key":"595_CR20","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1097\/01.prs.0000227682.71527.2b","volume":"118","author":"SL Moran","year":"2006","unstructured":"Moran SL, Shin AY, Bishop AT (2006) The use of massive bone allograft with intramedullary free fibular flap for limb salvage in a pediatric and adolescent population. Plast Reconstr Surg 118:413\u2013419","journal-title":"Plast Reconstr Surg"},{"key":"595_CR21","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1302\/0301-620X.79B1.0790036","volume":"79","author":"RW Hsu","year":"1997","unstructured":"Hsu RW, Wood M, Sim FH, Chao EY (1997) Free vascularized fibular grafting for reconstruction after tumour resection. J Bone Jt Surg Br 79:36\u201342","journal-title":"J Bone Jt Surg Br"},{"key":"595_CR22","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1097\/01.PRS.0000122213.82011.C5","volume":"113","author":"A Zaretski","year":"2004","unstructured":"Zaretski A, Amir A, Meller I, Leshem D, Kollender Y, Barnea Y, Bickels J, Shpitzer T, Ad-El D, Gur E (2004) Free fibula long bone reconstruction in orthopedic oncology: a surgical algorithm for reconstructive options. Plast Reconstr Surg 113:1989\u20132000","journal-title":"Plast Reconstr Surg"},{"key":"595_CR23","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1007\/s11999-008-0303-7","volume":"466","author":"DL Muscolo","year":"2008","unstructured":"Muscolo DL, Ayerza MA, Aponte-Tinao L, Farfalli G (2008) Allograft reconstruction after sarcoma resection in children younger than 10\u00a0years old. Clin Orthop Relat Res 466:1856\u20131862","journal-title":"Clin Orthop Relat Res"},{"key":"595_CR24","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.ocl.2005.08.003","volume":"37","author":"DL Muscolo","year":"2006","unstructured":"Muscolo DL, Ayerza MA, Aponte-Tinao LA (2006) Massive allograft use in orthopedic oncology. Orthop Clin North Am 37:65\u201374","journal-title":"Orthop Clin North Am"},{"issue":"6","key":"595_CR25","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1302\/0301-620X.92B6.23449","volume":"92","author":"SA Hanna","year":"2010","unstructured":"Hanna SA, Sewell MD, Aston WJ, Pollock RC, Skinner JA, Cannon SR, Briggs TW (2010) Femoral diaphyseal endoprosthetic reconstruction after segmental resection of primary bonetumours. J Bone Jt Surg Br 92(6):867\u2013874","journal-title":"J Bone Jt Surg Br"},{"key":"595_CR26","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1302\/0301-620X.96B11.34747","volume":"96","author":"ER Henderson","year":"2014","unstructured":"Henderson ER, O\u2019Connor MI, Ruggieri P, Windhager R, Funovics PT, Gibbons CL, Guo W, Hornicek FJ, Temple HT, Letson GD (2014) Classification of failure of limb salvage after reconstructive surgery for bone tumors: a modified system including biological and expandable reconstructions. Bone Jt J 96:1436\u20131440","journal-title":"Bone Jt J"},{"key":"595_CR27","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00003086-199301000-00035","volume":"286","author":"WF Enneking","year":"1993","unstructured":"Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ (1993) A system for the functional evaluation of reconstructive procedures after surgical treatment of the musculoskeletal system. Clin Orthop Relat Res 286:241\u2013246","journal-title":"Clin Orthop Relat Res"},{"issue":"3","key":"595_CR28","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1007\/s11999-016-4843-y","volume":"475","author":"JI Albergo","year":"2017","unstructured":"Albergo JI, Gaston CL, Aponte-Tinao LA, Ayerza MA, Muscolo DL, Farfalli GL, Jeys LM, Carter SR, Tillman RM, Abudu AT, Grimer RJ (2017) Proximal tibia reconstruction after bone tumor resection: are survivorship and outcomes of endoprosthetic replacement and osteoarticular allograft similar? Clin Orthop Relat Res 475(3):676\u2013682","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"595_CR29","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/s10561-012-9307-3","volume":"14","author":"LE Ritacco","year":"2013","unstructured":"Ritacco LE, Farfalli GL, Milano FE, Ayerza MA, Muscolo DL, Aponte-Tinao L (2013) Validity of an automatic measure protocol in distal femur for allograft selection from a three-dimensional virtual bone bank system. Cell Tissue Bank 14(2):213\u2013220","journal-title":"Cell Tissue Bank"},{"key":"595_CR30","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1302\/0301-620X.89B12.19481","volume":"89","author":"GJ Myers","year":"2007","unstructured":"Myers GJ, Abudu AT, Carter SR, Tillman RM, Grimer RJ (2007) The long-term results of endoprosthetic replacement of the proximal tibia for bone tumors. J Bone Jt Surg Br. 89:1632\u20131637","journal-title":"J Bone Jt Surg Br."},{"key":"595_CR31","unstructured":"R Core Team (2014) R: a language and environment for statistical computing. Vienna, Austria. http:\/\/www.Rproject.org . Accessed Aug 2016"},{"issue":"7","key":"595_CR32","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1302\/0301-620X.99B7.BJJ-2016-0996","volume":"299-B","author":"S Gupta","year":"2017","unstructured":"Gupta S, Kafchinski LA, Gundle KR, Saidi K, Griffin AM, Wunder JS, Ferguson PC (2017) Intercalary allograft augmented with intramedullary cement and plate fixation is a reliable solution after resection of a diaphyseal tumour. Bone Jt J 299-B(7):973\u2013978","journal-title":"Bone Jt J"},{"issue":"3","key":"595_CR33","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1302\/0301-620X.100B3.BJJ-2017-0283.R2","volume":"100-B","author":"DA Campanacci","year":"2018","unstructured":"Campanacci DA, Totti F, Puccini S, Beltrami G, Scoccianti G, Del Croix L, Innocenti M, Capanna R (2018) Intercalary reconstruction of femur after tumour resection: is a vascularized fibular autograft plus allograft a long-lasting solution? Bone Jt J 100-B(3):378\u2013386","journal-title":"Bone Jt J"},{"issue":"2","key":"595_CR34","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/j.injury.2013.10.012","volume":"45","author":"DA Campanacci","year":"2014","unstructured":"Campanacci DA, Puccini S, Caff G, Beltrami G, Piccioli A, Innocenti M, Capanna R (2014) Vascularized fibular grafts as a salvage procedure in failed intercalary reconstructions after bone tumor resection of the femur. Injury 45(2):399\u2013404","journal-title":"Injury"},{"key":"595_CR35","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1097\/01241398-200311000-00013","volume":"23","author":"M San-Julian","year":"2003","unstructured":"San-Julian M, Dolz R, Garcia-Barrecheguren E, Noain E, Sierrasesumaga L, Ca\u00f1adell J (2003) Limb salvage in bone sarcomas in patients younger than age 10: a 20-year experience. J Pediatr Orthop 23:753\u2013762","journal-title":"J Pediatr Orthop"}],"container-title":["MUSCULOSKELETAL SURGERY"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12306-019-00595-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12306-019-00595-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12306-019-00595-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T05:01:49Z","timestamp":1663045309000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12306-019-00595-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,8]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["595"],"URL":"https:\/\/doi.org\/10.1007\/s12306-019-00595-1","relation":{},"ISSN":["2035-5106","2035-5114"],"issn-type":[{"value":"2035-5106","type":"print"},{"value":"2035-5114","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,8]]},"assertion":[{"value":"22 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"On behalf of all authors, the corresponding author states that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}