{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T18:07:05Z","timestamp":1765303625671,"version":"3.46.0"},"reference-count":3,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Hematopathol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A 22-month-old previously healthy girl presented with profound microcytic anemia and severe thrombocytopenia due to iron deficiency. Following transfusions and iron supplementation, her platelet count rose dramatically, peaking at 3.5 million\/\u00b5L before gradually normalizing over several months. This case highlights the rare presentation of iron deficiency with severe thrombocytopenia, which can mimic bone marrow disorders. It also illustrates the phenomenon of rebound thrombocytosis after iron repletion, emphasizing the need for close platelet monitoring to mitigate potential thrombotic risk.<\/jats:p>","DOI":"10.1007\/s12308-025-00676-0","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T05:59:35Z","timestamp":1765259975000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["From famine to feast: a seesawing platelet count in severe iron deficiency anemia"],"prefix":"10.1007","volume":"18","author":[{"given":"Allison","family":"Weisnicht","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduard","family":"Matkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,9]]},"reference":[{"issue":"5","key":"676_CR1","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3109\/08880011003739455","volume":"27","author":"VK Morris","year":"2010","unstructured":"Morris VK, Spraker HL, Howard SC, Ware RE, Reiss UM (2010) Severe thrombocytopenia with iron deficiency anemia. Pediatr Hematol Oncol 27(5):413\u20139","journal-title":"Pediatr Hematol Oncol"},{"issue":"10","key":"676_CR2","doi-asserted-by":"publisher","first-page":"2299","DOI":"10.1007\/s00277-019-03757-0","volume":"98","author":"T Huscenot","year":"2019","unstructured":"Huscenot T, Darnige L, Wagner-Ballon O, Ronchetti AM, Lousteau V, Limal N, Morbieu C, Gobert D, Rohmer J, Mathian A, Le Cann M, Fadlallah J, Languille L, Michel M (2019) Iron deficiency, an unusual cause of thrombocytopenia: results from a multicenter retrospective case-controlled study. Ann Hematol 98(10):2299\u20132302","journal-title":"Ann Hematol"},{"issue":"8","key":"676_CR3","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1002\/ajh.26189","volume":"96","author":"E Brissot","year":"2021","unstructured":"Brissot E, Troadec MB, Lor\u00e9al O, Brissot P (2021Aug 1) Iron and platelets: A subtle, under-recognized relationship. Am J Hematol 96(8):1008\u20131016","journal-title":"Am J Hematol"}],"container-title":["Journal of Hematopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12308-025-00676-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12308-025-00676-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12308-025-00676-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T18:02:08Z","timestamp":1765303328000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12308-025-00676-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":3,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["676"],"URL":"https:\/\/doi.org\/10.1007\/s12308-025-00676-0","relation":{},"ISSN":["1868-9256","1865-5785"],"issn-type":[{"type":"print","value":"1868-9256"},{"type":"electronic","value":"1865-5785"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"18 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Consent waived by UW Human Research Protection Program.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Consent waived by UW Human Research Protection Program.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"57"}}