{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:58:10Z","timestamp":1790456290771,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:00:00Z","timestamp":1790380800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:00:00Z","timestamp":1790380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Hematopathol"],"DOI":"10.1007\/s12308-026-00738-x","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:28:16Z","timestamp":1790393296000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinicopathological spectrum and outcomes of biopsy-proven post-transplant lymphoproliferative disorder after kidney transplantation"],"prefix":"10.1007","volume":"19","author":[{"given":"Yagmur","family":"Tahillioglu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safak","family":"Mirioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunus","family":"Catma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabia Hacer","family":"Hocaoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Yilmaz","family":"Altay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metban","family":"Mastanzade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Burak","family":"Dirim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Serra","family":"Ucar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulcin","family":"Yegen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozgur Akin","family":"Oto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savas","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aydin","family":"Turkmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevgi Kalayoglu","family":"Besisik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halil","family":"Yazici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,26]]},"reference":[{"issue":"1","key":"738_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2024.151503","volume":"44","author":"VR Dharnidharka","year":"2024","unstructured":"Dharnidharka VR, Ruzinova MB, Marks LJ (2024) Post-transplant lymphoproliferative disorders. Semin Nephrol 44(1):151503","journal-title":"Semin Nephrol"},{"issue":"6","key":"738_CR2","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1056\/NEJMra1702693","volume":"378","author":"D Dierickx","year":"2018","unstructured":"Dierickx D, Habermann TM (2018) Post-transplantation lymphoproliferative disorders in adults. N Engl J Med 378(6):549\u2013562","journal-title":"N Engl J Med"},{"issue":"17","key":"738_CR3","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1001\/jama.2011.1592","volume":"306","author":"EA Engels","year":"2011","unstructured":"Engels EA, Pfeiffer RM, Fraumeni JF Jr., Kasiske BL, Israni AK, Snyder JJ et al (2011) Spectrum of cancer risk among US solid organ transplant recipients. JAMA 306(17):1891\u20131901","journal-title":"JAMA"},{"issue":"6","key":"738_CR4","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1093\/cid\/cit391","volume":"57","author":"J Styczynski","year":"2013","unstructured":"Styczynski J, Gil L, Tridello G, Ljungman P, Donnelly JP, van der Velden W et al (2013) Response to rituximab-based therapy and risk factor analysis in Epstein Barr Virus-related lymphoproliferative disorder after hematopoietic stem cell transplant in children and adults: a study from the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Clin Infect Dis 57(6):794\u2013802","journal-title":"Clin Infect Dis"},{"key":"738_CR5","volume-title":"WHO classification of tumours of haematopoietic and lymphoid tissues","year":"2017","unstructured":"Sscehnjepssht J (ed) (2017) WHO classification of tumours of haematopoietic and lymphoid tissues. International Agency for Research on Cancer (IARC), Lyon, France"},{"issue":"2","key":"738_CR6","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1046\/j.1600-6143.2003.00325.x","volume":"4","author":"G Opelz","year":"2004","unstructured":"Opelz G, D\u00f6hler B (2004) Lymphomas after solid organ transplantation: a collaborative transplant study report. Am J Transplant 4(2):222\u2013230","journal-title":"Am J Transplant"},{"issue":"11","key":"738_CR7","doi-asserted-by":"publisher","first-page":"2433","DOI":"10.3109\/10428194.2013.780655","volume":"54","author":"D Dierickx","year":"2013","unstructured":"Dierickx D, Tousseyn T, Sagaert X, Fieuws S, Wlodarska I, Morscio J et al (2013) Single-center analysis of biopsy-confirmed posttransplant lymphoproliferative disorder: incidence, clinicopathological characteristics and prognostic factors. Leuk Lymphoma 54(11):2433\u20132440","journal-title":"Leuk Lymphoma"},{"issue":"9","key":"738_CR8","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","volume":"150","author":"AS Levey","year":"2009","unstructured":"Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI et al (2009) A new equation to estimate glomerular filtration rate. Ann Intern Med 150(9):604\u2013612","journal-title":"Ann Intern Med"},{"issue":"5","key":"738_CR9","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1093\/ndt\/gfac335","volume":"38","author":"S Mirioglu","year":"2023","unstructured":"Mirioglu S, Dirim AB, Bektas M, Demir E, Tor YB, Ozluk Y et al (2023) Efficacy and safety of interleukin-1 blockers in kidney transplant recipients with familial Mediterranean fever: a propensity score-matched cohort study. Nephrol Dial Transplant 38(5):1327\u20131336","journal-title":"Nephrol Dial Transplant"},{"issue":"3","key":"738_CR10","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1093\/ndt\/gfn667","volume":"24","author":"SG Yarlagadda","year":"2009","unstructured":"Yarlagadda SG, Coca SG, Formica RN Jr., Poggio ED, Parikh CR (2009) Association between delayed graft function and allograft and patient survival: a systematic review and meta-analysis. Nephrol Dial Transplant 24(3):1039\u20131047","journal-title":"Nephrol Dial Transplant"},{"issue":"9","key":"738_CR11","doi-asserted-by":"publisher","first-page":"1834","DOI":"10.1097\/TP.0000000000004976","volume":"108","author":"CN Kotton","year":"2024","unstructured":"Kotton CN, Kamar N, Wojciechowski D, Eder M, Hopfer H, Randhawa P et al (2024) The second international consensus guidelines on the management of BK polyomavirus in kidney transplantation. Transplantation 108(9):1834\u20131866","journal-title":"Transplantation"},{"issue":"7","key":"738_CR12","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1097\/TP.0000000000005374","volume":"109","author":"CN Kotton","year":"2025","unstructured":"Kotton CN, Kumar D, Manuel O, Chou S, Hayden RT, Danziger-Isakov L et al (2025) The fourth international consensus guidelines on the management of cytomegalovirus in solid organ transplantation. Transplantation 109(7):1066\u20131110","journal-title":"Transplantation"},{"issue":"6","key":"738_CR13","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1097\/TP.0000000000002191","volume":"102","author":"CN Kotton","year":"2018","unstructured":"Kotton CN, Kumar D, Caliendo AM, Huprikar S, Chou S, Danziger-Isakov L et al (2018) The third international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation. Transplantation 102(6):900\u2013931","journal-title":"Transplantation"},{"key":"738_CR14","doi-asserted-by":"crossref","unstructured":"Green M, Michaels MG (2023) Epstein-Barr virus infection and posttransplant lymphoproliferative disorder. Am J Transplant 13(Suppl 3):41\u201354; quiz","DOI":"10.1111\/ajt.12004"},{"key":"738_CR15","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/978-1-62703-357-2_16","volume":"999","author":"LM Weiss","year":"2013","unstructured":"Weiss LM, Chen YY (2013) EBER in situ hybridization for Epstein-Barr virus. Methods Mol Biol 999:223\u2013230","journal-title":"Methods Mol Biol"},{"issue":"11","key":"738_CR16","first-page":"1860","volume":"31","author":"PP Carbone","year":"1971","unstructured":"Carbone PP, Kaplan HS, Musshoff K, Smithers DW, Tubiana M (1971) Report of the Committee on Hodgkin\u2019s Disease Staging Classification. Cancer Res 31(11):1860\u20131861","journal-title":"Cancer Res"},{"issue":"27","key":"738_CR17","doi-asserted-by":"publisher","first-page":"3059","DOI":"10.1200\/JCO.2013.54.8800","volume":"32","author":"BD Cheson","year":"2014","unstructured":"Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E et al (2014) Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol 32(27):3059\u20133068","journal-title":"J Clin Oncol"},{"issue":"38","key":"738_CR18","doi-asserted-by":"publisher","first-page":"41370","DOI":"10.18632\/oncotarget.5629","volume":"6","author":"XL Chen","year":"2015","unstructured":"Chen XL, Xue L, Wang W, Chen HN, Zhang WH, Liu K et al (2015) Prognostic significance of the combination of preoperative hemoglobin, albumin, lymphocyte and platelet in patients with gastric carcinoma: a retrospective cohort study. Oncotarget 6(38):41370\u201341382","journal-title":"Oncotarget"},{"issue":"6","key":"738_CR19","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1111\/j.1365-2141.2008.07149.x","volume":"141","author":"MJ Hourigan","year":"2008","unstructured":"Hourigan MJ, Doecke J, Mollee PN, Gill DS, Norris D, Johnson DW et al (2008) A new prognosticator for post-transplant lymphoproliferative disorders after renal transplantation. Br J Haematol 141(6):904\u2013907","journal-title":"Br J Haematol"},{"issue":"2","key":"738_CR20","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1002\/ajh.21911","volume":"86","author":"SC Quinlan","year":"2011","unstructured":"Quinlan SC, Pfeiffer RM, Morton LM, Engels EA (2011) Risk factors for early-onset and late-onset post-transplant lymphoproliferative disorder in kidney recipients in the United States. Am J Hematol 86(2):206\u2013209","journal-title":"Am J Hematol"},{"issue":"6","key":"738_CR21","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1200\/JCO.2009.25.4961","volume":"28","author":"AM Evens","year":"2010","unstructured":"Evens AM, David KA, Helenowski I, Nelson B, Kaufman D, Kircher SM et al (2010) Multicenter analysis of 80 solid organ transplantation recipients with post-transplantation lymphoproliferative disease: outcomes and prognostic factors in the modern era. J Clin Oncol 28(6):1038\u20131046","journal-title":"J Clin Oncol"},{"issue":"11","key":"738_CR22","doi-asserted-by":"publisher","first-page":"1676","DOI":"10.1097\/01.TP.0000144333.19106.58","volume":"78","author":"MJ Aull","year":"2004","unstructured":"Aull MJ, Buell JF, Trofe J, First MR, Alloway RR, Hanaway MJ et al (2004) Experience with 274 cardiac transplant recipients with posttransplant lymphoproliferative disorder: a report from the Israel Penn International Transplant Tumor Registry. Transplantation 78(11):1676\u20131682","journal-title":"Transplantation"},{"issue":"10","key":"738_CR23","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1200\/JCO.2012.43.2344","volume":"31","author":"S Caillard","year":"2013","unstructured":"Caillard S, Porcher R, Provot F, Dantal J, Choquet S, Durrbach A et al (2013) Post-transplantation lymphoproliferative disorder after kidney transplantation: report of a nationwide French registry and the development of a new prognostic score. J Clin Oncol 31(10):1302\u20131309","journal-title":"J Clin Oncol"},{"issue":"5","key":"738_CR24","doi-asserted-by":"publisher","first-page":"669","DOI":"10.3109\/0284186X.2013.844853","volume":"53","author":"A Kinch","year":"2014","unstructured":"Kinch A, Baecklund E, Backlin C, Ekman T, Molin D, Tufveson G et al (2014) A population-based study of 135 lymphomas after solid organ transplantation: the role of Epstein-Barr virus, hepatitis C and diffuse large B-cell lymphoma subtype in clinical presentation and survival. Acta Oncol 53(5):669\u2013679","journal-title":"Acta Oncol"},{"issue":"8","key":"738_CR25","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1111\/j.1600-6143.2006.01459.x","volume":"6","author":"NA Bakker","year":"2006","unstructured":"Bakker NA, Pruim J, de Graaf W, van Son WJ, van der Jagt EJ, van Imhoff GW (2006) PTLD visualization by FDG-PET: improved detection of extranodal localizations. Am J Transplant 6(8):1984\u20131985","journal-title":"Am J Transplant"},{"key":"738_CR26","doi-asserted-by":"crossref","unstructured":"(1993) A predictive model for aggressive non-Hodgkin's lymphoma. N Engl J Med 329(14):987\u201394","DOI":"10.1056\/NEJM199309303291402"},{"issue":"8","key":"738_CR27","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s00277-007-0298-2","volume":"86","author":"S Choquet","year":"2007","unstructured":"Choquet S, Oertel S, LeBlond V, Riess H, Varoqueaux N, D\u00f6rken B et al (2007) Rituximab in the management of post-transplantation lymphoproliferative disorder after solid organ transplantation: proceed with caution. Ann Hematol 86(8):599\u2013607","journal-title":"Ann Hematol"},{"issue":"3","key":"738_CR28","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1200\/JCO.2001.19.3.772","volume":"19","author":"V Leblond","year":"2001","unstructured":"Leblond V, Dhedin N, Mamzer Bruneel MF, Choquet S, Hermine O, Porcher R et al (2001) Identification of prognostic factors in 61 patients with posttransplantation lymphoproliferative disorders. J Clin Oncol 19(3):772\u2013778","journal-title":"J Clin Oncol"},{"issue":"30","key":"738_CR29","doi-asserted-by":"publisher","first-page":"7574","DOI":"10.1200\/JCO.2005.01.0934","volume":"23","author":"IM Ghobrial","year":"2005","unstructured":"Ghobrial IM, Habermann TM, Maurer MJ, Geyer SM, Ristow KM, Larson TS et al (2005) Prognostic analysis for survival in adult solid organ transplant recipients with post-transplantation lymphoproliferative disorders. J Clin Oncol 23(30):7574\u20137582","journal-title":"J Clin Oncol"},{"issue":"27","key":"738_CR30","doi-asserted-by":"publisher","first-page":"3443","DOI":"10.1200\/JCO.2013.50.3326","volume":"31","author":"D Dierickx","year":"2013","unstructured":"Dierickx D, Tousseyn T, Morscio J, Fieuws S, Verhoef G (2013) Validation of prognostic scores in post-transplantation lymphoproliferative disorders. J Clin Oncol 31(27):3443\u20133444","journal-title":"J Clin Oncol"},{"issue":"4","key":"738_CR31","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1111\/ajt.13086","volume":"15","author":"RU Trappe","year":"2015","unstructured":"Trappe RU, Choquet S, Dierickx D, Mollee P, Zaucha JM, Dreyling MH et al (2015) International prognostic index, type of transplant and response to rituximab are key parameters to tailor treatment in adults with CD20-positive B cell PTLD: clues from the PTLD-1 trial. Am J Transplant 15(4):1091\u20131100","journal-title":"Am J Transplant"},{"issue":"7","key":"738_CR32","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1038\/s41375-022-01620-2","volume":"36","author":"R Alaggio","year":"2022","unstructured":"Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBO, Berti E et al (2022) The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia 36(7):1720\u20131748","journal-title":"Leukemia"},{"issue":"11","key":"738_CR33","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1182\/blood.2022015850","volume":"140","author":"DA Arber","year":"2022","unstructured":"Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka H-M et al (2022) International consensus classification of myeloid neoplasms and acute leukemias: integrating morphologic, clinical, and genomic data. Blood 140(11):1200\u20131228","journal-title":"Blood"}],"container-title":["Journal of Hematopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12308-026-00738-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12308-026-00738-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12308-026-00738-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:03:13Z","timestamp":1790452993000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12308-026-00738-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,26]]},"references-count":33,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["738"],"URL":"https:\/\/doi.org\/10.1007\/s12308-026-00738-x","relation":{},"ISSN":["1865-5785"],"issn-type":[{"value":"1865-5785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,26]]},"assertion":[{"value":"13 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by the Institutional Ethics Committee of Istanbul University (approval number: 2025\/859). The study was conducted in accordance with the Declaration of Helsinki. Due to the retrospective design of the study, the requirement for informed consent was waived.","order":1,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"For this type of study formal consent is not required.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"For this type of study, consent for publication is not required.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No generative AI or AI-assisted technologies were used at any stage of the preparation of this manuscript, including writing, data analysis, interpretation of results, or figure generation.","order":4,"name":"Ethics","label":"Generative AI and AI-assisted technologies","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"58"}}