{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T18:40:49Z","timestamp":1772476849286,"version":"3.50.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,11,9]],"date-time":"2020-11-09T00:00:00Z","timestamp":1604880000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,11,9]],"date-time":"2020-11-09T00:00:00Z","timestamp":1604880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81901396"],"award-info":[{"award-number":["81901396"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Medical Science Research Grant of Guangdong Province","award":["B2018088"],"award-info":[{"award-number":["B2018088"]}]},{"name":"Medical Science Research Grant of Guangdong Province","award":["A2019439"],"award-info":[{"award-number":["A2019439"]}]},{"name":"The Sixth Affiliated Hospital of Sun Yat-Sen University Clinical Research \u2013 1010 Program","award":["1010PY(2020)-44"],"award-info":[{"award-number":["1010PY(2020)-44"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cerebellum"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s12311-020-01209-4","type":"journal-article","created":{"date-parts":[[2020,11,9]],"date-time":"2020-11-09T03:04:22Z","timestamp":1604891062000},"page":"246-253","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["3-Hz Postural Tremor in MSA-C and SCA: Revisiting an Old but Underestimated Cerebellar Sign by Posturography"],"prefix":"10.1007","volume":"20","author":[{"given":"Xiaodi","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Churong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinlong","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gengmao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9628-1382","authenticated-orcid":false,"given":"Yuzhou","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,11,9]]},"reference":[{"issue":"4","key":"1209_CR1","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/nrneurol.2017.26","volume":"13","author":"F Krismer","year":"2017","unstructured":"Krismer F, Wenning GK. Multiple system atrophy: insights into a rare and debilitating movement disorder. Nat Rev Neurol. 2017;13(4):232\u201343.","journal-title":"Nat Rev Neurol"},{"issue":"2","key":"1209_CR2","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.jns.2006.05.064","volume":"249","author":"I Yabe","year":"2006","unstructured":"Yabe I, Soma H, Takei A, Fujiki N, Yanagihara T, Sasaki H. MSA-C is the predominant clinical phenotype of MSA in Japan: analysis of 142 patients with probable MSA. J Neurol Sci. 2006;249(2):115\u201321.","journal-title":"J Neurol Sci"},{"issue":"19","key":"1209_CR3","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1212\/WNL.0000000000000965","volume":"83","author":"HJ Kim","year":"2014","unstructured":"Kim HJ, Jeon BS, Shin J, Lee WW, Park H, Jung YJ, et al. Should genetic testing for SCAs be included in the diagnostic workup for MSA? Neurology. 2014;83(19):1733\u20138.","journal-title":"Neurology."},{"issue":"12","key":"1209_CR4","doi-asserted-by":"publisher","first-page":"2764","DOI":"10.1007\/s00415-018-8876-x","volume":"265","author":"M Li","year":"2018","unstructured":"Li M, Ma Q, Zhao X, Wang C, Wu H, Li J, et al. Dilemma of multiple system atrophy and spinocerebellar ataxias. J Neurol. 2018;265(12):2764\u201372.","journal-title":"J Neurol"},{"issue":"1","key":"1209_CR5","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.clinph.2016.10.012","volume":"128","author":"Y Terao","year":"2016","unstructured":"Terao Y, Fukuda H, Tokushige S, et al. Distinguishing spinocerebellar ataxia with pure cerebellar manifestation from multiple system atrophy (MSA-C) through saccade profiles. Clin Neurophysiol. 2016;128(1):31.","journal-title":"Clin Neurophysiol"},{"issue":"3","key":"1209_CR6","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1111\/j.1600-0404.1969.tb01241.x","volume":"45","author":"BP Silfverskiold","year":"1969","unstructured":"Silfverskiold BP. Romberg\u2019s test in the cerebellar syndrome occurring in chronic alcoholism. Acta Neurol Scand. 1969;45(3):292\u2013302.","journal-title":"Acta Neurol Scand"},{"issue":"3","key":"1209_CR7","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1093\/brain\/102.3.461","volume":"102","author":"KH Mauritz","year":"1979","unstructured":"Mauritz KH, Dichgans J, Hufschmidt A. Quantitative analysis of stance in late cortical cerebellar atrophy of the anterior lobe and other forms of cerebellar ataxia. Brain. 1979;102(3):461\u201382.","journal-title":"Brain."},{"issue":"2","key":"1209_CR8","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/0013-4694(84)90172-X","volume":"57","author":"HC Diener","year":"1984","unstructured":"Diener HC, Dichgans J, Bacher M, Gompf B. Quantification of postural sway in normals and patients with cerebellar diseases. Electroencephalogr Clin Neurophysiol. 1984;57(2):134\u201342.","journal-title":"Electroencephalogr Clin Neurophysiol"},{"issue":"8","key":"1209_CR9","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1093\/cercor\/bhj048","volume":"16","author":"EV Sullivan","year":"2006","unstructured":"Sullivan EV, Rose J, Pfefferbaum A. Effect of vision, touch and stance on cerebellar vermian-related sway and tremor: a quantitative physiological and MRI study. Cereb Cortex. 2006;16(8):1077\u201386.","journal-title":"Cereb Cortex"},{"issue":"1","key":"1209_CR10","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s10072-017-3130-3","volume":"39","author":"X Li","year":"2018","unstructured":"Li X, Wang Y, Wang Z, Xu Y, Zheng W. 3-Hz postural tremor in multiple system atrophy cerebellar type (MSA-C): a static posturography study. Neurol Sci. 2018;39(1):71\u20137.","journal-title":"Neurol Sci"},{"issue":"2","key":"1209_CR11","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/j.1600-0404.1973.tb01294.x","volume":"49","author":"BY Nilsson","year":"1973","unstructured":"Nilsson BY, Silfverskiold BP. Electromyographic recordings of slow leg tremor in chronic alcoholics. Acta Neurol Scand. 1973;49(2):227\u201332.","journal-title":"Acta Neurol Scand"},{"issue":"11","key":"1209_CR12","first-page":"1105","volume":"34","author":"M Asahina","year":"1994","unstructured":"Asahina M, Nakajima M, Kojima S, Hirayama K. Postural sway in patients with hereditary ataxia. Rinsho Shinkeigaku. 1994;34(11):1105\u201310.","journal-title":"Rinsho Shinkeigaku"},{"issue":"1","key":"1209_CR13","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.biopsych.2009.08.008","volume":"67","author":"EV Sullivan","year":"2010","unstructured":"Sullivan EV, Rose J, Pfefferbaum A. Physiological and focal cerebellar substrates of abnormal postural sway and tremor in alcoholic women. Biol Psychiatry. 2010;67(1):44\u201351.","journal-title":"Biol Psychiatry"},{"key":"1209_CR14","doi-asserted-by":"publisher","first-page":"492","DOI":"10.5334\/tohm.346","volume":"7","author":"SR Gan","year":"2017","unstructured":"Gan SR, Wang J, Figueroa KP. Postural tremor and ataxia progression in spinocerebellar ataxias. Tremor Other Hyperkinet Mov (N Y). 2017;7:492.","journal-title":"Tremor Other Hyperkinet Mov (N Y)"},{"key":"1209_CR15","doi-asserted-by":"publisher","first-page":"2460","DOI":"10.1007\/s00415-012-6531-5","volume":"11","author":"C Bonnet","year":"2012","unstructured":"Bonnet C, Apartis E, Anheim M. Tremor-spectrum in spinocerebellar ataxia type 3. J Neurol. 2012;11:2460\u201370.","journal-title":"J Neurol"},{"key":"1209_CR16","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.jocn.2015.10.027","volume":"27","author":"H Sarva","year":"2016","unstructured":"Sarva H, Severt WL, Jacoby N. Secondary orthostatic tremor in the setting of cerebellar degeneration. J Clin Neurosci. 2016;27:173\u20135.","journal-title":"J Clin Neurosci"},{"issue":"9","key":"1209_CR17","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1212\/01.wnl.0000324625.00404.15","volume":"71","author":"S Gilman","year":"2008","unstructured":"Gilman S, Wenning GK, Low PA. Second consensus statement on the diagnosis of multiple system atrophy. Neurology. 2008;71(9):670\u20136.","journal-title":"Neurology."},{"issue":"6","key":"1209_CR18","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1097\/01.mao.0000194891.26097.e0","volume":"26","author":"M Karlberg","year":"2005","unstructured":"Karlberg M, Fransson PA, Magnusson M. Posturography can be used to screen for primary orthostatic tremor, a rare cause of dizziness. Otol Neurotol. 2005;26(6):1200\u20133.","journal-title":"Otol Neurotol"},{"issue":"6","key":"1209_CR19","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1002\/mds.23579","volume":"26","author":"R Elble","year":"2011","unstructured":"Elble R, Deuschl G. Milestones in tremor research. Mov Disord. 2011;26(6):1096\u2013105.","journal-title":"Mov Disord"},{"issue":"8","key":"1209_CR20","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1016\/j.parkreldis.2015.05.021","volume":"21","author":"K Feil","year":"2015","unstructured":"Feil K, Bottcher N, Guri F. Long-term course of orthostatic tremor in serial posturographic measurement. Parkinsonism Relat Disord. 2015;21(8):905\u201310.","journal-title":"Parkinsonism Relat Disord"},{"issue":"1","key":"1209_CR21","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/S0966-6362(00)00097-7","volume":"13","author":"K Yarrow","year":"2001","unstructured":"Yarrow K, Brown P, Gresty MA. Force platform recordings in the diagnosis of primary orthostatic tremor. Gait Posture. 2001;13(1):27\u201334.","journal-title":"Gait Posture"},{"issue":"8","key":"1209_CR22","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/j.parkreldis.2014.05.006","volume":"20","author":"JA van Gerpen","year":"2014","unstructured":"van Gerpen JA. A retrospective study of the clinical and electrophysiological characteristics of 32 patients with orthostatic myoclonus. Parkinsonism Relat Disord. 2014;20(8):889\u201393.","journal-title":"Parkinsonism Relat Disord"},{"issue":"2","key":"1209_CR23","first-page":"173","volume":"21","author":"J Spiegel","year":"2006","unstructured":"Spiegel J, Krick C, Fuss G. Orthostatic tremor during modification of standing. Clin Neurophysiol. 2006;21(2):173\u20138.","journal-title":"Clin Neurophysiol"},{"issue":"Pt 1","key":"1209_CR24","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1093\/brain\/104.1.97","volume":"104","author":"KH Mauritz","year":"1981","unstructured":"Mauritz KH, Schmitt C, Dichgans J. Delayed and enhanced long latency reflexes as the possible cause of postural tremor in late cerebellar atrophy. Brain. 1981;104(Pt 1):97\u2013116.","journal-title":"Brain."},{"key":"1209_CR25","doi-asserted-by":"publisher","first-page":"324","DOI":"10.5334\/tohm.238","volume":"5","author":"HB Rigby","year":"2015","unstructured":"Rigby HB, Rigby MH, Caviness JN. Orthostatic tremor: a spectrum of fast and slow frequencies or distinct entities? Tremor Other Hyperkinet Mov (N Y). 2015;5:324.","journal-title":"Tremor Other Hyperkinet Mov (N Y)"},{"issue":"8","key":"1209_CR26","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1002\/mds.21992","volume":"23","author":"M Kollensperger","year":"2008","unstructured":"Kollensperger M, Geser F, Seppi K. Red flags for multiple system atrophy. Mov Disord. 2008;23(8):1093\u20139.","journal-title":"Mov Disord"},{"issue":"10","key":"1209_CR27","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1212\/01.WNL.0000028690.15001.00","volume":"59","author":"Y Osaki","year":"2002","unstructured":"Osaki Y, Wenning GK, Daniel SE. Do published criteria improve clinical diagnostic accuracy in multiple system atrophy? Neurology. 2002;59(10):1486\u201391.","journal-title":"Neurology"},{"key":"1209_CR28","first-page":"781479","volume":"2015","author":"L Wermuth","year":"2015","unstructured":"Wermuth L, Cui X, Greene N. Medical record review to differentiate between idiopathic Parkinson\u2019s disease and Parkinsonism: a Danish record linkage study with 10 years of follow-up. Parkinsons Dis. 2015;2015:781479.","journal-title":"Parkinsons Dis"},{"issue":"8","key":"1209_CR29","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1002\/mds.20486","volume":"20","author":"BP Van de Warrenburg","year":"2005","unstructured":"Van de Warrenburg BP, Bakker M, Kremer BP. Trunk sway in patients with spinocerebellar ataxia. Mov Disord. 2005;20(8):1006\u201313.","journal-title":"Mov Disord"},{"key":"1209_CR30","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1212\/WNL.51.3.923-a","volume":"51","author":"F Setta","year":"1998","unstructured":"Setta F, Manto MU. Orthostatic tremor associated with a pontine lesion or cerebellar disease. Neurology. 1998;51:923.","journal-title":"Neurology."},{"issue":"5","key":"1209_CR31","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1212\/WNL.49.5.1439","volume":"49","author":"J Benito-Le\u00f3n","year":"1997","unstructured":"Benito-Le\u00f3n J, Rodr\u00edguez J, Ort\u00ed-Pareja M. Symptomatic orthostatic tremor in pontine lesions. Neurology. 1997;49(5):1439\u201341.","journal-title":"Neurology."},{"key":"1209_CR32","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1002\/mds.1045","volume":"16","author":"YR Wu","year":"2001","unstructured":"Wu YR, Ashby P, Lang AE. Orthostatic tremor arises from an oscillator in the posterior fossa. Mov Disord. 2001;16:272\u20139.","journal-title":"Mov Disord"},{"issue":"3","key":"1209_CR33","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1212\/WNL.46.3.747","volume":"46","author":"AJ Wills","year":"1996","unstructured":"Wills AJ, Thompson PD, Findley LJ. A positron emission tomography study of primary orthostatic tremor. Neurology. 1996;46(3):747\u201352.","journal-title":"Neurology."}],"updated-by":[{"DOI":"10.1007\/s12311-022-01372-w","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000}}],"container-title":["The Cerebellum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-020-01209-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12311-020-01209-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-020-01209-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T11:37:48Z","timestamp":1646307468000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12311-020-01209-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,9]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["1209"],"URL":"https:\/\/doi.org\/10.1007\/s12311-020-01209-4","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s12311-022-01372-w","asserted-by":"object"}]},"ISSN":["1473-4222","1473-4230"],"issn-type":[{"value":"1473-4222","type":"print"},{"value":"1473-4230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,9]]},"assertion":[{"value":"26 October 2020","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 November 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2022","order":3,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":4,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":5,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s12311-022-01372-w","URL":"https:\/\/doi.org\/10.1007\/s12311-022-01372-w","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interests"}},{"value":"This study was approved by the local institution\u2019s ethics committees.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}