{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:33:18Z","timestamp":1787236398999,"version":"build-2736575974"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI14C3477"],"award-info":[{"award-number":["HI14C3477"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["NRF-2016R1D1A1B04935568"],"award-info":[{"award-number":["NRF-2016R1D1A1B04935568"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cerebellum"],"DOI":"10.1007\/s12311-021-01356-2","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T19:04:10Z","timestamp":1641495850000},"page":"1-13","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Ocular Motor Findings Aid in Differentiation of Spinocerebellar Ataxia Type 17 from Huntington\u2019s Disease"],"prefix":"10.1007","volume":"22","author":[{"given":"Sun-Uk","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1508-2024","authenticated-orcid":false,"given":"Ji-Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dallah","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aryun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo-Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Yoon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Yun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Hae","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun-Woo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,7]]},"reference":[{"issue":"9","key":"1356_CR1","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1002\/mds.25464","volume":"28","author":"JS Kim","year":"2013","unstructured":"Kim JS, Kim JS, Youn J, Seo DW, Jeong Y, Kang JH, et al. Ocular motor characteristics of different subtypes of spinocerebellar ataxia: distinguishing features. Mov Disord. 2013;28(9):1271\u20137.","journal-title":"Mov Disord"},{"key":"1356_CR2","doi-asserted-by":"crossref","unstructured":"Schelhaas HJ, Ippel PF, Beemer FA, Hageman. Similarities and differences in the phenotype, genotype and pathogenesis of different spinocerebellar ataxias. Eur J Neurol. 2000;7(3):309\u201314.","DOI":"10.1046\/j.1468-1331.2000.00067.x"},{"issue":"6","key":"1356_CR3","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1002\/ana.410420615","volume":"42","author":"L Sch\u00f6ls","year":"1997","unstructured":"Sch\u00f6ls L, Amoiridis G, B\u00fcttner T, Przuntek H, Epplen JT, Riess O. Autosomal dominant cerebellar ataxia: phenotypic differences in genetically defined subtypes? Ann Neurol. 1997;42(6):924\u201332.","journal-title":"Ann Neurol"},{"issue":"2","key":"1356_CR4","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1212\/01.WNL.0000103293.63340.C1","volume":"62","author":"K B\u00fcrk","year":"2004","unstructured":"B\u00fcrk K, Z\u00fchlke C, K\u00f6nig IR, Ziegler A, Schwinger E, Globas C, et al. Spinocerebellar ataxia type 5 Clinical and molecular genetic features of a German kindred. Neurology. 2004;62(2):327\u20139.","journal-title":"Neurology"},{"issue":"4","key":"1356_CR5","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1136\/jnnp.65.4.565","volume":"65","author":"JC Jen","year":"1998","unstructured":"Jen JC, Yue Q, Karrim J, Nelson SF, Baloh RW. Spinocerebellar ataxia type 6 with positional vertigo and acetazolamide responsive episodic ataxia. J Neurol Neurosurg Psychiatry. 1998;65(4):565\u20138.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"4","key":"1356_CR6","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1007\/s00415-003-1020-5","volume":"250","author":"I Yabe","year":"2003","unstructured":"Yabe I, Sasaki H, Takeichi N, Takei A, Hamada T, Fukushima K, et al. Positional vertigo and macroscopic downbeat positioning nystagmus in spinocerebellar ataxia type 6 (SCA6). J Neurol. 2003;250(4):440\u20133.","journal-title":"J Neurol"},{"issue":"10","key":"1356_CR7","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1002\/mds.10511","volume":"18","author":"T Hashimoto","year":"2003","unstructured":"Hashimoto T, Sasaki O, Yoshida K, Takei Y, Ikeda S. Periodic alternating nystagmus and rebound nystagmus in spinocerebellar ataxia type 6. Mov Disord. 2003;18(10):1201\u20134.","journal-title":"Mov Disord"},{"issue":"9","key":"1356_CR8","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1007\/s004150050456","volume":"246","author":"K B\u00fcrk","year":"1999","unstructured":"B\u00fcrk K, Fetter M, Abele M, Laccone F, Brice A, Dichgans J, Klockether T. Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3. J Neurol. 1999;246(9):789\u201397.","journal-title":"J Neurol"},{"issue":"6","key":"1356_CR9","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1002\/ana.1059","volume":"49","author":"AK Oh","year":"2001","unstructured":"Oh AK, Jacobson KM, Jen JC, Baloh RW. Slowing of voluntary and involuntary saccades: an early sign in spinocerebellar ataxia type 7. Ann Neurol. 2001;49(6):801\u20134.","journal-title":"Ann Neurol"},{"issue":"11","key":"1356_CR10","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1093\/hmg\/8.11.2047","volume":"8","author":"R Koide","year":"1999","unstructured":"Koide R, Kobayashi S, Shimohata T, Ikeuchi T, Maruyama M, Saito M, et al. A neurological disease caused by an expanded CAG trinucleotide repeat in the TATA-binding protein gene: a new polyglutamine disease? Hum Mol Genet. 1999;8(11):2047\u201353.","journal-title":"Hum Mol Genet"},{"issue":"11","key":"1356_CR11","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1007\/s00415-007-0579-7","volume":"254","author":"C Mariotti","year":"2007","unstructured":"Mariotti C, Alpini D, Fancellu R, Soliveri P, Grisoli M, Ravaglia S. Spinocerebellar ataxia type 17 (SCA17): oculomotor phenotype and clinical characterization of 15 Italian patients. J Neurol. 2007;254(11):1538\u201346.","journal-title":"J Neurol"},{"issue":"3","key":"1356_CR12","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1002\/ana.10676","volume":"54","author":"A Rolfs","year":"2003","unstructured":"Rolfs A, Koeppen AH, Bauer I, Bauer P, Buhlmann S, Topka H, et al. Clinical features and neuropathology of autosomal dominant spinocerebellar ataxia (SCA17). Ann Neurol. 2003;54(3):367\u201375.","journal-title":"Ann Neurol"},{"issue":"9","key":"1356_CR13","doi-asserted-by":"publisher","first-page":"2341","DOI":"10.1093\/brain\/awl148","volume":"129","author":"K Lasek","year":"2006","unstructured":"Lasek K, Lencer R, Gaser C, Hagenah J, Walter U, Wolters A, Kock N, et al. Morphological basis for the spectrum of clinical deficits in spinocerebellar ataxia 17 (SCA17). Brain. 2006;129(9):2341\u201352.","journal-title":"Brain"},{"issue":"6","key":"1356_CR14","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","volume":"72","author":"MC O'Donovan","year":"1993","unstructured":"O\u2019Donovan MC. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes. Cell. 1993;72(6):971\u201383.","journal-title":"Cell"},{"issue":"1","key":"1356_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/nrdp.2015.5","volume":"1","author":"GP Bates","year":"2015","unstructured":"Bates GP, Dorsey R, Gusella JF, Hayden MR, Kay C, Leavitt BR, et al. Huntington disease. Nat Rev Dis Primers. 2015;1(1):1\u201321.","journal-title":"Nat Rev Dis Primers"},{"issue":"2","key":"1356_CR16","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1007\/s12311-008-0016-1","volume":"7","author":"G Stevanin","year":"2008","unstructured":"Stevanin G, Brice A. Spinocerebellar ataxia 17 (SCA17) and Huntington\u2019s disease-like 4 (HDL4). Cerebellum. 2008;7(2):170\u20138.","journal-title":"Cerebellum"},{"issue":"9","key":"1356_CR17","doi-asserted-by":"publisher","first-page":"1701","DOI":"10.1212\/01.wnl.0000242740.01273.00","volume":"67","author":"SA Schneider","year":"2006","unstructured":"Schneider SA, van de Warrenburg BPC, Hughes TD, Davis M, Sweeney M, Wood N, et al. Phenotypic homogeneity of the Huntington disease\u2013like presentation in a SCA17 family. Neurology. 2006;67(9):1701\u20133.","journal-title":"Neurology"},{"issue":"11","key":"1356_CR18","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1212\/01.wnl.0000276958.91986.89","volume":"69","author":"J H\u00fcbner","year":"2007","unstructured":"H\u00fcbner J, Sprenger A, Klein C, Hagenah J, Rambold H, Z\u00fchlke C, et al. Eye movement abnormalities in spinocerebellar ataxia type 17 (SCA17). Neurology. 2007;69(11):1160\u20138.","journal-title":"Neurology"},{"issue":"7","key":"1356_CR19","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1097\/MLG.0b013e31805c08ac","volume":"117","author":"KD Choi","year":"2007","unstructured":"Choi KD, Oh SY, Kim HJ, Koo JW, Cho BM, Kim JS. Recovery of vestibular imbalances after vestibular neuritis. Laryngoscope. 2007;117(7):1307\u201312.","journal-title":"Laryngoscope"},{"issue":"2","key":"1356_CR20","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3988\/jcn.2010.6.2.51","volume":"6","author":"SH Lee","year":"2010","unstructured":"Lee SH, Kim JS. Benign paroxysmal positional vertigo. J Clin Neurol. 2010;6(2):51\u201363.","journal-title":"J Clin Neurol"},{"issue":"7","key":"1356_CR21","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1001\/archneur.1988.00520310043015","volume":"45","author":"GM Halmagyi","year":"1988","unstructured":"Halmagyi GM, Curthoys IS. A clinical sign of canal paresis. Arch Neurol. 1988;45(7):737\u20139.","journal-title":"Arch Neurol"},{"issue":"4","key":"1356_CR22","doi-asserted-by":"publisher","first-page":"203","DOI":"10.3988\/jcn.2013.9.4.203","volume":"9","author":"YE Huh","year":"2013","unstructured":"Huh YE, Kim JS. Bedside evaluation of dizzy patients. J Clin Neurol. 2013;9(4):203\u201313.","journal-title":"J Clin Neurol"},{"issue":"22","key":"1356_CR23","doi-asserted-by":"publisher","first-page":"2238","DOI":"10.1212\/WNL.0000000000001640","volume":"84","author":"JY Choi","year":"2015","unstructured":"Choi JY, Kim JH, Kim HJ, Glasauer S, Kim JS. Central paroxysmal positional nystagmus characteristics and possible mechanisms. Neurology. 2015;84(22):2238\u201346.","journal-title":"Neurology"},{"issue":"24","key":"1356_CR24","doi-asserted-by":"publisher","first-page":"e2135","DOI":"10.1212\/WNL.0000000000005689","volume":"90","author":"SU Lee","year":"2018","unstructured":"Lee SU, Choi JY, Kim HJ, Kim JS. Recurrent spontaneous vertigo with interictal headshaking nystagmus. Neurology. 2018;90(24):e2135\u201345.","journal-title":"Neurology"},{"issue":"2","key":"1356_CR25","doi-asserted-by":"publisher","first-page":"74","DOI":"10.3988\/jcn.2009.5.2.74","volume":"5","author":"Y Yang","year":"2009","unstructured":"Yang Y, Kim JS, Kim S, Kim YK, Kwak YT, Han IW. Cerebellar hypoperfusion during transient global amnesia: an MRI and oculographic study. J Clin Neurol. 2009;5(2):74\u201380.","journal-title":"J Clin Neurol"},{"issue":"5","key":"1356_CR26","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1007\/s00415-018-8868-x","volume":"265","author":"SU Lee","year":"2018","unstructured":"Lee SU, Kim HJ, Choi JY, Kim JS. Lower brainstem melanocytoma masquerading as vestibular paroxysmia. J Neurol. 2018;265(5):1222\u20135.","journal-title":"J Neurol"},{"issue":"6","key":"1356_CR27","doi-asserted-by":"publisher","first-page":"e744","DOI":"10.1097\/MAO.0000000000002645","volume":"41","author":"SU Lee","year":"2020","unstructured":"Lee SU, Kim HJ, Choi JY, Koo JW, Yang X, Kim JS. Evolution in the findings of head-impulse tests during the attacks of Meni\u00e8re\u2019s disease. Otol Neurotol. 2020;41(6):e744\u201350.","journal-title":"Otol Neurotol"},{"issue":"8","key":"1356_CR28","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.1007\/s00415-011-6375-4","volume":"259","author":"JS Kim","year":"2012","unstructured":"Kim JS, Kim HJ. Inferior vestibular neuritis. J Neurol. 2012;259(8):1553\u201360.","journal-title":"J Neurol"},{"issue":"1","key":"1356_CR29","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s12311-016-0772-2","volume":"16","author":"SU Lee","year":"2017","unstructured":"Lee SU, Choi JY, Kiim HJ, Park JJ, Zee DS, Kim JS. Impaired tilt suppression of post-rotatory nystagmus and cross-coupled head-shaking nystagmus in cerebellar lesions: image mapping study. Cerebellum. 2017;16(1):95\u2013102.","journal-title":"Cerebellum"},{"issue":"6","key":"1356_CR30","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1001\/archneur.58.6.899","volume":"58","author":"LB Jardim","year":"2001","unstructured":"Jardim LB, Pereira ML, Selveira I, Ferro A, Sequeiros J, Giugliani R. Neurologic findings in Machado-Joseph disease: relation with disease duration, subtypes, and (CAG) n. Arch Neurol. 2001;58(6):899\u2013904.","journal-title":"Arch Neurol"},{"issue":"4","key":"1356_CR31","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1097\/WNO.0b013e318183bf5a","volume":"28","author":"CB Colen","year":"2008","unstructured":"Colen CB, Ketko A, George E, Van Stavern GP. Periodic alternating nystagmus and periodic alternating skew deviation in spinocerebellar ataxia type 6. J Neuroophthalmol. 2008;28(4):287\u20138.","journal-title":"J Neuroophthalmol"},{"issue":"6","key":"1356_CR32","first-page":"512","volume":"38","author":"I Yabe","year":"1998","unstructured":"Yabe I, Sasaki H, Yamashita I, Suzuki Y, Tahiro K. Periodic alternating nystagmus in spinocerebellar ataxia type 6 (SCA 6). Rinsho Shinkeigaku. 1998;38(6):512\u20135.","journal-title":"Rinsho Shinkeigaku"},{"issue":"4","key":"1356_CR33","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1001\/archneur.65.4.530","volume":"65","author":"P Christova","year":"2008","unstructured":"Christova P, Anderson JH, Gomez CM. Impaired eye movements in presymptomatic spinocerebellar ataxia type 6. Arch Neurol. 2008;65(4):530\u20136.","journal-title":"Arch Neurol"},{"issue":"7","key":"1356_CR34","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/S1474-4422(13)70104-2","volume":"12","author":"H Jacobi","year":"2013","unstructured":"Jacobi H, Reetz K, du Mentcel ST, Bauer P, Mariotti C, Nanetti L, et al. Biological and clinical characteristics of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 in the longitudinal RISCA study: analysis of baseline data. Lancet Neurol. 2013;12(7):650\u20138.","journal-title":"Lancet Neurol"},{"issue":"3","key":"1356_CR35","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1007\/s12311-015-0650-3","volume":"14","author":"YE Huh","year":"2015","unstructured":"Huh YE, Kim JS, Kim HJ, Park SH, Jeon BS, Kim JM, et al. Vestibular pPerformance during high-acceleration stimuli correlates with clinical decline in SCA6. Cerebellum. 2015;14(3):284\u201391.","journal-title":"Cerebellum"},{"issue":"6","key":"1356_CR36","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.1007\/s00415-020-09756-w","volume":"267","author":"SU Lee","year":"2020","unstructured":"Lee SU, Kim JS, Kim HJ, Choi JY, Park JY, Kim JM, et al. Evolution of the vestibular function during head impulses in spinocerebellar ataxia type 6. J Neurol. 2020;267(6):1672\u20138.","journal-title":"J Neurol"},{"issue":"11","key":"1356_CR37","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.1002\/mds.20529","volume":"20","author":"CT Loy","year":"2005","unstructured":"Loy CT, Sweeney MG, Davis MB, Willis AJ, Sawle GV, Lees AJ, et al. Spinocerebellar ataxia type 17: extension of phenotype with putaminal rim hyperintensity on magnetic resonance imaging. Mov Disord. 2005;20(11):1521\u20133.","journal-title":"Mov Disord"},{"issue":"24","key":"1356_CR38","doi-asserted-by":"publisher","first-page":"3639","DOI":"10.1016\/S0042-6989(96)00169-1","volume":"37","author":"AG Lasker","year":"1997","unstructured":"Lasker AG, Zee DS. Ocular motor abnormalities in Huntington\u2019s disease. Vision Res. 1997;37(24):3639\u201345.","journal-title":"Vision Res"},{"issue":"3","key":"1356_CR39","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s00221-007-1248-x","volume":"186","author":"A Peltsch","year":"2008","unstructured":"Peltsch A, Hoffman A, Armstrong I, Pari G, Munoz DP. Saccadic impairments in Huntington\u2019s disease. Exp Brain Res. 2008;186(3):457\u201369.","journal-title":"Exp Brain Res"},{"key":"1356_CR40","doi-asserted-by":"publisher","first-page":"A48","DOI":"10.1136\/jnnp-2014-309032.136","volume":"85","author":"L Luis","year":"2014","unstructured":"Luis L, Costa J, Munoz E, Schneider E, Vallas-Sole J. F01 Vestibular ccular reflex dynamics during passive head-impulses: slow phase and quick-eye movements in Huntington\u2019s disease. J Neurol Neurosurg Psychiatry. 2014;85:A48.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"5","key":"1356_CR41","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1002\/ana.410130508","volume":"13","author":"N Aronin","year":"1983","unstructured":"Aronin N, Cooper PE, Lorenz LJ, Bird ED, Sagar SM, Leeman SE, Martin JB. Somatostatin is increased in the basal ganglia in Huntington disease. Ann Neurol. 1983;13(5):519\u201326.","journal-title":"Ann Neurol"},{"issue":"1","key":"1356_CR42","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/j.1365-2990.2008.00994.x","volume":"35","author":"U R\u00fcb","year":"2009","unstructured":"R\u00fcb U, Heinsen H, Brunt ER, Landwehrmeyer B, Den Dunnen WFA, Gierga K, et al. The human premotor oculomotor brainstem system\u2013can it help to understand oculomotor symptoms in Huntington\u2019s disease? Neuropathol Appl Neurobiol. 2009;35(1):4\u201315.","journal-title":"Neuropathol Appl Neurobiol"},{"issue":"2","key":"1356_CR43","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1007\/s00415-018-9076-4","volume":"266","author":"R Sullivan","year":"2019","unstructured":"Sullivan R, Yau WY, O\u2019Connor E, Houlden H. Spinocerebellar ataxia: an update. J Neurol. 2019;266(2):533\u201344.","journal-title":"J Neurol"},{"issue":"11","key":"1356_CR44","doi-asserted-by":"publisher","first-page":"3504","DOI":"10.1161\/STROKEAHA.109.551234","volume":"40","author":"JC Kattah","year":"2009","unstructured":"Kattah JC, Talkad AV, Wang DZ, Hsieh YH, Newman-Toker DE. HINTS to diagnose stroke in the acute vestibular syndrome three-step bedside oculomotor examination more sensitive than early MRI diffusion-weighted imaging. Stroke. 2009;40(11):3504\u201310.","journal-title":"Stroke"},{"issue":"11","key":"1356_CR45","doi-asserted-by":"publisher","first-page":"3081","DOI":"10.1161\/STROKEAHA.115.010972","volume":"46","author":"SU Lee","year":"2015","unstructured":"Lee SU, Park SH, Park JJ, Kim HJ, Han MK, Bae HJ, et al. Dorsal medullary infarction distinct syndrome of isolated central vestibulopathy. Stroke. 2015;46(11):3081\u20137.","journal-title":"Stroke"},{"issue":"6","key":"1356_CR46","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1007\/s00415-013-6837-y","volume":"260","author":"HK Park","year":"2013","unstructured":"Park HK, Kim JS, Strupp M, Zee DS. Isolated floccular infarction: impaired vestibular responses to horizontal head impulse. J Neurol. 2013;260(6):1576\u201382.","journal-title":"J Neurol"},{"issue":"3","key":"1356_CR47","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1113\/jphysiol.1977.sp011747","volume":"265","author":"M Ito","year":"1977","unstructured":"Ito M, Nisimaru N, Yamamoto M. Specific patterns of neuronal connexions involved in the control of the rabbit\u2019s vestibulo-ocular reflexes by the cerebellar flocculus. J Physiol. 1977;265(3):833\u201354.","journal-title":"J Physiol"},{"key":"1356_CR48","doi-asserted-by":"crossref","unstructured":"Kim JG, Kim SH, Lee SU, Lee CN, Kim BJ, Kim JS, et al. Head-impulse tests aid in differentiation of multiple system atrophy from Parkinson\u2019s disease. J Neurol. 2021;Nov 12.[Epub ahead of print].","DOI":"10.1007\/s00415-021-10885-z"},{"key":"1356_CR49","doi-asserted-by":"publisher","first-page":"46","DOI":"10.3389\/fneur.2018.00046","volume":"9","author":"JC Kattah","year":"2018","unstructured":"Kattah JC. Clinical characteristics and etiology of bilateral vestibular loss in a cohort from central Illinois. Front Neurol. 2018;9:46.","journal-title":"Front Neurol"},{"issue":"5\u20136","key":"1356_CR50","doi-asserted-by":"publisher","first-page":"351","DOI":"10.3233\/VES-140527","volume":"24","author":"CR Gordon","year":"2014","unstructured":"Gordon CR, Zivotofsky AZ, Caspi A. Impaired vestibulo-ocular reflex (VOR) in spinocerebellar ataxia type 3 (SCA3): bedside and search coil evaluation. J Vestib Res. 2014;24(5\u20136):351\u20135.","journal-title":"J Vestib Res"},{"issue":"3","key":"1356_CR51","doi-asserted-by":"publisher","first-page":"327","DOI":"10.3233\/VES-160579","volume":"26","author":"L Luis","year":"2016","unstructured":"Luis L, Costa J, Munoz E, de Carvalho M, Carmona S, Schneider E, et al. Vestibulo-ocular reflex dynamics with head-impulses discriminates spinocerebellar ataxias types 1, 2 and 3 and Friedreich ataxia. J Vestib Res. 2016;26(3):327\u201334.","journal-title":"J Vestib Res"},{"issue":"3","key":"1356_CR52","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1093\/brain\/awp323","volume":"133","author":"AG Shaikh","year":"2010","unstructured":"Shaikh AG, Hong S, Liao K, Tian J, Solomon D, Zee DS, et al. Oculopalatal tremor explained by a model of inferior olivary hypertrophy and cerebellar plasticity. Brain. 2010;133(3):923\u201340.","journal-title":"Brain"},{"issue":"14","key":"1356_CR53","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1212\/01.wnl.0000258665.37827.f6","volume":"68","author":"JS Kim","year":"2007","unstructured":"Kim JS, Moon SY, Choi KD, Kim JH, Sharpe JA. Patterns of ocular oscillation in oculopalatal tremor imaging correlations. Neurology. 2007;68(14):1128\u201335.","journal-title":"Neurology"},{"issue":"3","key":"1356_CR54","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1093\/brain\/awx381","volume":"141","author":"JY Choi","year":"2018","unstructured":"Choi JY, Glasauer S, Kim JH, Zee DS, Kim JS. Characteristics and mechanism of apogeotropic central positional nystagmus. Brain. 2018;141(3):762\u201375.","journal-title":"Brain"},{"issue":"1","key":"1356_CR55","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s12311-011-0292-z","volume":"11","author":"H Jacobi","year":"2012","unstructured":"Jacobi H, Hauser TK, Giunti P, Globas C, Bauer P, Schmitz-H\u00fcbsch T, et al. Spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings. Cerebellum. 2012;11(1):155\u201366.","journal-title":"Cerebellum"},{"issue":"2","key":"1356_CR56","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S0022-510X(98)00250-0","volume":"160","author":"H Harada","year":"1998","unstructured":"Harada H, Tamaoka A, Watanabe M, Ishikawa K, Shoji S. Downbeat nystagmus in two siblings with spinocerebellar ataxia type 6 (SCA 6). J Neurol Sci. 1998;160(2):161\u20133.","journal-title":"J Neurol Sci"},{"issue":"1\u20132","key":"1356_CR57","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.jns.2010.01.021","volume":"292","author":"T Tsunemi","year":"2010","unstructured":"Tsunemi T, Ishikawa K, Tsukui K, Sumi T, Kitamura K, Mizusawa H, et al. The effect of 3, 4-diaminopyridine on the patients with hereditary pure cerebellar ataxia. J Neurol Sci. 2010;292(1\u20132):81\u20134.","journal-title":"J Neurol Sci"},{"issue":"1","key":"1356_CR58","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s00415-009-0068-2","volume":"256","author":"P Yu-Wai-Man","year":"2009","unstructured":"Yu-Wai-Man P, Gorman G, Bateman DE, Leigh RJ, Chinnery PF. Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6. J Neurol. 2009;256(1):78\u201382.","journal-title":"J Neurol"},{"issue":"13","key":"1356_CR59","doi-asserted-by":"publisher","first-page":"e1255","DOI":"10.1212\/WNL.0000000000006250","volume":"91","author":"DV Seshagiri","year":"2018","unstructured":"Seshagiri DV, Pal PK, Jain S, Yadav R. Optokinetic nystagmus in patients with SCA: a bedside test for oculomotor dysfunction grading. Neurology. 2018;91(13):e1255\u201361.","journal-title":"Neurology"},{"key":"1356_CR60","doi-asserted-by":"crossref","unstructured":"Rivaud\u2010Pechoux S, D\u00fcrr A, Gaymard B, Cancel G, Ploner CJ, Agid Y,e t al. Eye movement abnormalities correlate with genotype in autosomal dominant cerebellar ataxia type I. Ann Neurol. 1998;43(3):297\u2013302.","DOI":"10.1002\/ana.410430306"},{"issue":"6","key":"1356_CR61","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1212\/WNL.53.6.1355","volume":"53","author":"G Stevanin","year":"1999","unstructured":"Stevanin G, Herman A, Brice A, D\u00fcrr A. Clinical and MRI findings in spinocerebellar ataxia type 5. Neurology. 1999;53(6):1355.","journal-title":"Neurology"},{"issue":"1","key":"1356_CR62","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1136\/jnnp.67.1.86","volume":"67","author":"K Ishikawa","year":"1999","unstructured":"Ishikawa K, Watanabe M, Yoshizawa K, Fujita T, Iwamoto H, Yoshizawa T, et al. linical, neuropathological, and molecular study in two families with spinocerebellar ataxia type 6 (SCA6). J Neurol Neurosurg PSychiatry. 1999;67(1):86\u20139.","journal-title":"J Neurol Neurosurg PSychiatry"},{"issue":"6","key":"1356_CR63","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1007\/s00401-005-1014-8","volume":"109","author":"K Gierga","year":"2005","unstructured":"Gierga K, B\u00fcrk K, Bauer M, Orozco Diaz G, Auburger G, Schultz C, et al. Involvement of the cranial nerves and their nuclei in spinocerebellar ataxia type 2 (SCA2). Acta Neuropathol. 2005;109(6):617\u201331.","journal-title":"Acta Neuropathol"},{"issue":"1","key":"1356_CR64","first-page":"36","volume":"29","author":"KM Doherty","year":"2014","unstructured":"Doherty KM, Warner TT, Lees AJ. Late onset ataxia: MSA-C or SCA 17? A gene penetrance dilemma Mov Disord. 2014;29(1):36\u20138.","journal-title":"A gene penetrance dilemma Mov Disord"},{"issue":"6","key":"1356_CR65","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1001\/archneur.60.6.858","volume":"60","author":"WY Lee","year":"2003","unstructured":"Lee WY, Jin DK, Oh MR, Lee JE, Song SM, Lee EA, et al. Frequency analysis and clinical characterization of spinocerebellar ataxia types 1, 2, 3, 6, and 7 in Korean patients. Arch Neurol. 2003;60(6):858\u201363.","journal-title":"Arch Neurol"}],"container-title":["The Cerebellum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-021-01356-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12311-021-01356-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-021-01356-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T19:55:53Z","timestamp":1674935753000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12311-021-01356-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,7]]},"references-count":65,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["1356"],"URL":"https:\/\/doi.org\/10.1007\/s12311-021-01356-2","relation":{},"ISSN":["1473-4230"],"issn-type":[{"value":"1473-4230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,7]]},"assertion":[{"value":"2 December 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2022","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study followed the tenets of the Declaration of Helsinki, and was performed according to the guidelines of Institutional Review Board of Seoul National University Bundang Hospital (B-1811\u2013505-119), Korea University Medical Center (2021AN0177), Ulsan University Hospital (2021\u201304-031), Chungnam National University Hospital (2021\u201303-053\u2013003), and Kyung Hee University Hospital (2021\u201304-091).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Standard"}},{"value":"S. U. Lee, D. Yoo, A. Kim, H. J. Kim, J. Y. Choi, J. Y. Park, S. H. Jeong, J. M. Kim, and K. W. Park report no disclosures.J. S. Kim serves as an Associate Editor of Frontiers in Neuro-otology and on the editorial boards of the Journal of Clinical Neurology, Frontiers in Neuro-ophthalmology, Journal of Neuro-ophthalmology, Journal of Vestibular Research, Medicine, and Clinical and Translational Neuroscience.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}