{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T17:31:04Z","timestamp":1775842264126,"version":"3.50.1"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"IDEALAB"},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["406.XS.04.073"],"award-info":[{"award-number":["406.XS.04.073"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["VI.Vidi.201.003"],"award-info":[{"award-number":["VI.Vidi.201.003"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cerebellum"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Pediatric cerebellar tumor survivors may present with spontaneous language impairments following treatment, but the nature of these impairments is still largely unclear. A recent study by Svaldi et al. (Cerebellum. 23:523-44, 2023) found a broad spectrum of spontaneous language impairments irrespective of postoperative cerebellar mutism syndrome (pCMS) diagnosis in long-term pediatric cerebellar tumor survivors. Several patients presented with reduced grammatical or lexical accuracy, but a detailed error analysis was lacking. The present study builds on this study by 1) investigating the error types in spontaneous language across three language processing levels in the same participant group and 2) by evaluating the possible association between pCMS and the processing nature of the language impairments. Spontaneous language was evaluated in 12 long-term survivors of pediatric cerebellar tumors (<jats:italic>M<\/jats:italic>(<jats:italic>SD<\/jats:italic>)\u2009=\u20094;8(3;8) years), of whom five were diagnosed with pCMS. The proportion of occurrence of each error type was compared between each patient and five matched controls using individual case statistics, reflecting (lexico-)phonological (i.e., phonemic paraphasias), lexical-semantic (e.g., empty speech) and morphosyntactic processing (e.g., verb inflection errors). Each patient showed a significantly higher proportion of at least one of the included error types across all language processing levels. A higher proportion of general-all-purpose verbs and inaccurate verb inflection were the most common errors and respectively reflected lexical-semantic and morphosyntactic processing. Additional language impairments were identified using the error analysis that were not identified with standard language measures and psycholinguistic analysis, suggesting the added diagnostic value of error analyses.<\/jats:p>","DOI":"10.1007\/s12311-024-01754-2","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T03:58:18Z","timestamp":1736222298000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Errors in the Spontaneous Language of Survivors of Pediatric Cerebellar Tumors"],"prefix":"10.1007","volume":"24","author":[{"given":"Cheyenne","family":"Svaldi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan-Ignacio","family":"Galli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Paquier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Keulen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrieke","family":"Van Elp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coriene","family":"Catsman-Berrevoets","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annet","family":"Kingma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roel","family":"Jonkers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia","family":"Kohnen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00e2nia","family":"de Aguiar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"1754_CR1","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1093\/neuonc\/nou357","volume":"18","author":"V Ramaswamy","year":"2016","unstructured":"Ramaswamy V, Remke M, Adamski J, Bartels U, Tabori U, Wang X, et al. Medulloblastoma subgroup-specific outcomes in irradiated children: Who are the true high-risk patients? Neuro Oncol. 2016;18:291\u20137.","journal-title":"Neuro Oncol"},{"key":"1754_CR2","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1007\/s00381-019-04229-6","volume":"36","author":"PF Paquier","year":"2020","unstructured":"Paquier PF, Walsh KS, Docking KM, Hartley H, Kumar R, Catsman-Berrevoets CE. Post-operative cerebellar mutism syndrome: Rehabilitation issues. Child\u2019s Nervous System. 2020;36:1215\u201322.","journal-title":"Child\u2019s Nervous System"},{"key":"1754_CR3","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s12311-019-01088-4","volume":"19","author":"S C\u00e1mara","year":"2020","unstructured":"C\u00e1mara S, Fournier C, Cordero P, Melero J, Robles F, Esteso B, et al. Neuropsychological profile in children with posterior fossa tumors with or without postoperative cerebellar mutism syndrome (CMS). Cerebellum. 2020;19:78\u201388.","journal-title":"Cerebellum"},{"key":"1754_CR4","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1007\/s00381-016-3093-3","volume":"32","author":"T Gudrunardottir","year":"2016","unstructured":"Gudrunardottir T, Morgan AT, Lux AL, Walker DA, Walsh KS, Wells EM, et al. Consensus paper on post-operative pediatric cerebellar mutism syndrome: The Iceland Delphi results. Child\u2019s Nervous Syst. 2016;32:1195\u2013203.","journal-title":"Child\u2019s Nervous Syst"},{"key":"1754_CR5","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1093\/brain\/123.5.1051","volume":"123","author":"D Riva","year":"2000","unstructured":"Riva D, Giorgi C. The cerebellum contributes to higher functions during development: Evidence from a series of children surgically treated for posterior fossa tumours. Brain. 2000;123:1051\u201361.","journal-title":"Brain"},{"key":"1754_CR6","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.ejpn.2023.12.005","volume":"48","author":"C Svaldi","year":"2024","unstructured":"Svaldi C, Ntemou E, Jonkers R, Kohnen S, de Aguiar V. Language outcomes in children who underwent surgery for the removal of a posterior fossa tumor: A systematic review. Eur J Paediatr Neurol. 2024;48:129\u201341.","journal-title":"Eur J Paediatr Neurol"},{"key":"1754_CR7","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s12311-023-01563-z","volume":"23","author":"C Svaldi","year":"2023","unstructured":"Svaldi C, Paquier P, Keulen S, van Elp H, Catsman-Berrevoets C, Kingma A, et al. Characterising the long-term language impairments of children following cerebellar tumour surgery by extracting psycholinguistic properties from spontaneous language. Cerebellum. 2023;23:523\u201344.","journal-title":"Cerebellum"},{"key":"1754_CR8","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1080\/02699052.2021.1970806","volume":"35","author":"K Docking","year":"2021","unstructured":"Docking K, Knijnik SR. Prospective longitudinal decline in cognitive-communication skills following treatment for childhood brain tumor. Brain Inj. 2021;35:1472\u20139.","journal-title":"Brain Inj"},{"key":"1754_CR9","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/j.ejpn.2011.12.013","volume":"16","author":"HJ De Smet","year":"2012","unstructured":"De Smet HJ, Catsman-Berrevoets C, Aarsen F, Verhoeven J, Mari\u00ebn P, Paquier PF. Auditory-perceptual speech analysis in children with cerebellar tumours: a long-term follow-up study. Eur J Paediatr Neurol. 2012;16:434\u201342.","journal-title":"Eur J Paediatr Neurol"},{"key":"1754_CR10","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1016\/S0028-3932(01)00224-X","volume":"40","author":"JR Crawford","year":"2002","unstructured":"Crawford JR, Garthwaite PH. Investigation of the single case in neuropsychology: Confidence limits on the abnormality of test scores and test score differences. Neuropsychologia. 2002;40:1196\u2013208.","journal-title":"Neuropsychologia"},{"key":"1754_CR11","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1007\/s12311-011-0273-2","volume":"10","author":"C Di Rocco","year":"2011","unstructured":"Di Rocco C, Chieffo D, Frassanito P, Caldarelli M, Massimi L, Tamburrini G. Heralding cerebellar mutism: Evidence for pre-surgical language impairment as primary risk factor in posterior fossa surgery. Cerebellum. 2011;10:551\u201362.","journal-title":"Cerebellum"},{"issue":"1","key":"1754_CR12","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s00381-023-06119-4","volume":"40","author":"K Persson","year":"2023","unstructured":"Persson K, Boeg Thomsen D, Fyrberg \u00c5, Castor C, AasvedHjort M, Andreozzi B, et al. Preoperative word-finding difficulties in children with posterior fossa tumours: A European cross-sectional study. Childs Nerv Syst. 2023;40(1):87\u201397.","journal-title":"Childs Nerv Syst."},{"key":"1754_CR13","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1044\/jshr.3903.643","volume":"39","author":"M Dunn","year":"1996","unstructured":"Dunn M, Flax J, Sliwinski M, Aram D. The use of spontaneous language measures as criteria for identifying children with Specific Language Impairment: An attempt to reconcile clinical and research incongruence. J Speech Lang Hear Res. 1996;39:643\u201354.","journal-title":"J Speech Lang Hear Res"}],"container-title":["The Cerebellum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-024-01754-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12311-024-01754-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-024-01754-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T18:06:20Z","timestamp":1737569180000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12311-024-01754-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,7]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["1754"],"URL":"https:\/\/doi.org\/10.1007\/s12311-024-01754-2","relation":{},"ISSN":["1473-4230"],"issn-type":[{"value":"1473-4230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,7]]},"assertion":[{"value":"25 November 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. According to Dutch law, no approval of a Medical Ethical Committee is needed when patient data are studied that are obtained as part of routine patient care. Ethical approval for the collection of data from participants without neurological or language impairments was obtained from the Research Ethics Committee (CETO) from the faculty of arts of the University of Groningen (review number 76303408).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"As is required by Dutch law, parents and patients over 12\u00a0years old signed a consent form before neuropsychological assessment in which they allowed the data to be used for research.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}],"article-number":"26"}}