{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:49:50Z","timestamp":1793321390675,"version":"4.5.0"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R21MH131941"],"award-info":[{"award-number":["R21MH131941"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Boston Children\u2019s Anesthesia Foundation"},{"DOI":"10.13039\/100006367","name":"Tommy Fuss Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006367","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Timothy O'Neill Foundation"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cerebellum"],"DOI":"10.1007\/s12311-025-01822-1","type":"journal-article","created":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T18:05:35Z","timestamp":1742666735000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Reduced Cerebellar Volumes Associate with P300 Amplitude Attenuation in Children with Clinical High Risk for Psychosis and Early Onset Psychosis"],"prefix":"10.1007","volume":"24","author":[{"given":"Hanne","family":"van der Heijden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hesham M.","family":"Hamoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliza","family":"Ray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Goldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Golden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey","family":"Graber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank H.","family":"Duffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"D\u2019Angelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borjan","family":"Gagoski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merve Ko\u00e7","family":"Yeked\u00fcz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carter R.","family":"Petty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaymin","family":"Upadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Gonzalez-Heydrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,21]]},"reference":[{"issue":"2","key":"1822_CR1","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.biopsych.2008.01.003","volume":"64","author":"NC Andreasen","year":"2008","unstructured":"Andreasen NC, Pierson R. The role of the cerebellum in schizophrenia. Biol Psychiatry. 2008;64(2):81\u20138.","journal-title":"Biol Psychiatry"},{"issue":"1","key":"1822_CR2","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1038\/s41398-023-02586-0","volume":"13","author":"C Andreou","year":"2023","unstructured":"Andreou C, Eickhoff S, Heide M, de Bock R, Obleser J, Borgwardt S. Predictors of transition in patients with clinical high risk for psychosis: an umbrella review. Transl Psychiatry. 2023;13(1):286.","journal-title":"Transl Psychiatry"},{"issue":"7","key":"1822_CR3","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1176\/appi.ajp.2018.18040429","volume":"176","author":"RO Brady Jr","year":"2019","unstructured":"Brady RO Jr., Gonsalvez I, Lee I, Ongur D, Seidman LJ, Schmahmann JD, Eack SM, Keshavan MS, Pascual-Leone A, Halko MA. Cerebellar-Prefrontal network connectivity and negative symptoms in schizophrenia. Am J Psychiatry. 2019;176(7):512\u201320.","journal-title":"Am J Psychiatry"},{"key":"1822_CR4","doi-asserted-by":"crossref","unstructured":"Cannon TD, Chung Y, He G, Sun D, Jacobson A, van Erp TG, McEwen S, Addington J, Bearden CE, Cadenhead K, Cornblatt B, Mathalon DH, McGlashan T, Perkins D, Jeffries C, Seidman LJ, Tsuang M, Walker E, Woods SW, Heinssen R. North American Prodrome Longitudinal Study, C., 2015. Progressive reduction in cortical thickness as psychosis develops: a multisite longitudinal neuroimaging study of youth at elevated clinical risk. Biol Psychiatry 77 (2), 147\u2013157.","DOI":"10.1016\/j.biopsych.2014.05.023"},{"issue":"1","key":"1822_CR5","doi-asserted-by":"publisher","first-page":"3836","DOI":"10.1038\/s41467-018-06350-7","volume":"9","author":"H Cao","year":"2018","unstructured":"Cao H, Chen OY, Chung Y, Forsyth JK, McEwen SC, Gee DG, Bearden CE, Addington J, Goodyear B, Cadenhead KS, Mirzakhanian H, Cornblatt BA, Carrion RE, Mathalon DH, McGlashan TH, Perkins DO, Belger A, Seidman LJ, Thermenos H, Tsuang MT, van Erp TGM, Walker EF, Hamann S, Anticevic A, Woods SW, Cannon TD. Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization. Nat Commun. 2018;9(1):3836.","journal-title":"Nat Commun"},{"issue":"8","key":"1822_CR6","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1001\/jamapsychiatry.2021.1290","volume":"78","author":"A Catalan","year":"2021","unstructured":"Catalan A, Salazar de Pablo G, Aymerich C, Damiani S, Sordi V, Radua J, Oliver D, McGuire P, Giuliano AJ, Stone WS, Fusar-Poli P. Neurocognitive functioning in individuals at clinical high risk for psychosis: A systematic review and Meta-analysis. JAMA Psychiatry. 2021;78(8):859\u201367.","journal-title":"JAMA Psychiatry"},{"key":"1822_CR7","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1186\/1471-244X-12-150","volume":"12","author":"L Clemmensen","year":"2012","unstructured":"Clemmensen L, Vernal DL, Steinhausen HC. A systematic review of the long-term outcome of early onset schizophrenia. BMC Psychiatry. 2012;12:150.","journal-title":"BMC Psychiatry"},{"key":"1822_CR8","doi-asserted-by":"publisher","first-page":"14005","DOI":"10.1038\/npjschz.2014.5","volume":"1","author":"CM Diaz-Caneja","year":"2015","unstructured":"Diaz-Caneja CM, Pina-Camacho L, Rodriguez-Quiroga A, Fraguas D, Parellada M, Arango C. Predictors of outcome in early-onset psychosis: a systematic review. NPJ Schizophr. 2015;1:14005.","journal-title":"NPJ Schizophr"},{"issue":"1","key":"1822_CR9","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.neuroimage.2006.05.056","volume":"33","author":"J Diedrichsen","year":"2006","unstructured":"Diedrichsen J. A spatially unbiased atlas template of the human cerebellum. NeuroImage. 2006;33(1):127\u201338.","journal-title":"NeuroImage"},{"issue":"1","key":"1822_CR10","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.neuroimage.2009.01.045","volume":"46","author":"J Diedrichsen","year":"2009","unstructured":"Diedrichsen J, Balsters JH, Flavell J, Cussans E, Ramnani N. A probabilistic MR atlas of the human cerebellum. NeuroImage. 2009;46(1):39\u201346.","journal-title":"NeuroImage"},{"key":"1822_CR11","first-page":"79","volume":"3","author":"S Frangou","year":"2010","unstructured":"Frangou S. Cognitive function in early onset schizophrenia: a selective review. Front Hum Neurosci. 2010;3:79.","journal-title":"Front Hum Neurosci"},{"issue":"1","key":"1822_CR12","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.neuroimage.2010.11.075","volume":"55","author":"P Fusar-Poli","year":"2011","unstructured":"Fusar-Poli P, Crossley N, Woolley J, Carletti F, Perez-Iglesias R, Broome M, Johns L, Tabraham P, Bramon E, McGuire P. Gray matter alterations related to P300 abnormalities in subjects at high risk for psychosis: longitudinal MRI-EEG study. NeuroImage. 2011a;55(1):320\u20138.","journal-title":"NeuroImage"},{"issue":"4","key":"1822_CR13","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1503\/jpn.100083","volume":"36","author":"P Fusar-Poli","year":"2011","unstructured":"Fusar-Poli P, Crossley N, Woolley J, Carletti F, Perez-Iglesias R, Broome M, Johns L, Tabraham P, Bramon E, McGuire P. White matter alterations related to P300 abnormalities in individuals at high risk for psychosis: an MRI-EEG study. J Psychiatry Neurosci. 2011b;36(4):239\u201348.","journal-title":"J Psychiatry Neurosci"},{"issue":"4","key":"1822_CR14","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/j.neubiorev.2006.11.006","volume":"31","author":"P Fusar-Poli","year":"2007","unstructured":"Fusar-Poli P, Perez J, Broome M, Borgwardt S, Placentino A, Caverzasi E, Cortesi M, Veggiotti P, Politi P, Barale F, McGuire P. Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis. Neurosci Biobehav Rev. 2007;31(4):465\u201384.","journal-title":"Neurosci Biobehav Rev"},{"key":"1822_CR15","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1523\/JNEUROSCI.1312-23.2024","volume":"44","author":"F Ge","year":"2024","unstructured":"Ge F, Wang Z, Yu W, Yuan X, Cai Q, Wang G, Li X, Xu X, Yang P, Fan Y, Chang J, Guan X. Activating lobule VI PC(TH+)-Med pathway in cerebellum blocks the acquisition of methamphetamine conditioned place preference in mice. J Neurosci. 2024;44:11.","journal-title":"J Neurosci"},{"key":"1822_CR16","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.schres.2018.12.029","volume":"210","author":"K Graber","year":"2019","unstructured":"Graber K, Bosquet Enlow M, Duffy FH, D\u2019Angelo E, Sideridis G, Hyde DE, Morelli N, Tembulkar S, Gonzalez-Heydrich J. P300 amplitude Attenuation in high risk and early onset psychosis youth. Schizophr Res. 2019;210:228\u201338.","journal-title":"Schizophr Res"},{"issue":"3","key":"1822_CR17","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.pscychresns.2011.02.010","volume":"193","author":"D Greenstein","year":"2011","unstructured":"Greenstein D, Lenroot R, Clausen L, Chavez A, Vaituzis AC, Tran L, Gogtay N, Rapoport J. Cerebellar development in childhood onset schizophrenia and non-psychotic siblings. Psychiatry Res. 2011;193(3):131\u20137.","journal-title":"Psychiatry Res"},{"issue":"8","key":"1822_CR18","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.biopsych.2007.09.018","volume":"63","author":"MJ Groom","year":"2008","unstructured":"Groom MJ, Bates AT, Jackson GM, Calton TG, Liddle PF, Hollis C. Event-related potentials in adolescents with schizophrenia and their siblings: a comparison with attention-deficit\/hyperactivity disorder. Biol Psychiatry. 2008;63(8):784\u201392.","journal-title":"Biol Psychiatry"},{"issue":"1","key":"1822_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12311-019-01083-9","volume":"19","author":"X Guell","year":"2020","unstructured":"Guell X, Schmahmann J. Cerebellar functional anatomy: a didactic summary based on human fMRI evidence. Cerebellum. 2020;19(1):1\u20135.","journal-title":"Cerebellum"},{"key":"1822_CR20","doi-asserted-by":"crossref","unstructured":"Guell X, Schmahmann JD, Gabrieli J, Ghosh SS. 2018. Functional gradients of the cerebellum. Elife 7.","DOI":"10.7554\/eLife.36652"},{"key":"1822_CR21","doi-asserted-by":"publisher","first-page":"108757","DOI":"10.1016\/j.biopsycho.2024.108757","volume":"187","author":"HK Hamilton","year":"2024","unstructured":"Hamilton HK, Mathalon DH, Ford JM. P300 in schizophrenia: then and now. Biol Psychol. 2024;187:108757.","journal-title":"Biol Psychol"},{"issue":"12","key":"1822_CR22","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1176\/ajp.154.12.1663","volume":"154","author":"LK Jacobsen","year":"1997","unstructured":"Jacobsen LK, Giedd JN, Berquin PC, Krain AL, Hamburger SD, Kumra S, Rapoport JL. Quantitative morphology of the cerebellum and fourth ventricle in childhood-onset schizophrenia. Am J Psychiatry. 1997;154(12):1663\u20139.","journal-title":"Am J Psychiatry"},{"issue":"11","key":"1822_CR23","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1016\/j.biopsych.2009.07.021","volume":"66","author":"J Janssen","year":"2009","unstructured":"Janssen J, Reig S, Aleman Y, Schnack H, Udias JM, Parellada M, Graell M, Moreno D, Zabala A, Balaban E, Desco M, Arango C. Gyral and sulcal cortical thinning in adolescents with first episode early-onset psychosis. Biol Psychiatry. 2009;66(11):1047\u201354.","journal-title":"Biol Psychiatry"},{"issue":"5","key":"1822_CR24","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1111\/1469-8986.00070","volume":"40","author":"YW Jeon","year":"2003","unstructured":"Jeon YW, Polich J. Meta-analysis of P300 and schizophrenia: patients, paradigms, and practical implications. Psychophysiology. 2003;40(5):684\u2013701.","journal-title":"Psychophysiology"},{"issue":"1","key":"1822_CR25","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/s41537-024-00434-8","volume":"10","author":"N Kang","year":"2024","unstructured":"Kang N, Chung S, Lee SH, Bang M. Cerebro-cerebellar Gray matter abnormalities associated with cognitive impairment in patients with recent-onset and chronic schizophrenia. Schizophrenia (Heidelb). 2024;10(1):11.","journal-title":"Schizophrenia (Heidelb)"},{"key":"1822_CR26","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/7854_2022_387","volume":"63","author":"NR Karcher","year":"2023","unstructured":"Karcher NR, Merchant J, Pine J, Kilciksiz CM. Cognitive dysfunction as a risk factor for psychosis. Curr Top Behav Neurosci. 2023;63:173\u2013203.","journal-title":"Curr Top Behav Neurosci"},{"issue":"1","key":"1822_CR27","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1176\/appi.ajp.160.1.128","volume":"160","author":"A Keller","year":"2003","unstructured":"Keller A, Castellanos FX, Vaituzis AC, Jeffries NO, Giedd JN, Rapoport JL. Progressive loss of cerebellar volume in childhood-onset schizophrenia. Am J Psychiatry. 2003;160(1):128\u201333.","journal-title":"Am J Psychiatry"},{"issue":"3","key":"1822_CR28","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1017\/S0048577299981337","volume":"36","author":"R Kilpelainen","year":"1999","unstructured":"Kilpelainen R, Koistinen A, Kononen M, Herrgard E, Partanen J, Karhu J. P300 sequence effects differ between children and adults for auditory stimuli. Psychophysiology. 1999;36(3):343\u201350.","journal-title":"Psychophysiology"},{"key":"1822_CR29","doi-asserted-by":"publisher","first-page":"286","DOI":"10.3389\/fpsyt.2018.00286","volume":"9","author":"T Kim","year":"2018","unstructured":"Kim T, Lee KH, Oh H, Lee TY, Cho KIK, Lee J, Kwon JS. Cerebellar structural abnormalities associated with cognitive function in patients with First-Episode psychosis. Front Psychiatry. 2018;9:286.","journal-title":"Front Psychiatry"},{"issue":"12","key":"1822_CR30","doi-asserted-by":"publisher","first-page":"5074","DOI":"10.1002\/hbm.24346","volume":"39","author":"JA Kipping","year":"2018","unstructured":"Kipping JA, Xie Y, Qiu A. Cerebellar development and its mediation role in cognitive planning in childhood. Hum Brain Mapp. 2018;39(12):5074\u201384.","journal-title":"Hum Brain Mapp"},{"issue":"1","key":"1822_CR31","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1038\/s41386-021-01137-9","volume":"47","author":"SM Kolk","year":"2022","unstructured":"Kolk SM, Rakic P. Development of prefrontal cortex. Neuropsychopharmacology. 2022;47(1):41\u201357.","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"1822_CR32","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1007\/s12311-013-0511-x","volume":"13","author":"LF Koziol","year":"2014","unstructured":"Koziol LF, Budding D, Andreasen N, D\u2019Arrigo S, Bulgheroni S, Imamizu H, Ito M, Manto M, Marvel C, Parker K, Pezzulo G, Ramnani N, Riva D, Schmahmann J, Vandervert L, Yamazaki T. Consensus paper: the cerebellum\u2019s role in movement and cognition. Cerebellum. 2014;13(1):151\u201377.","journal-title":"Cerebellum"},{"key":"1822_CR33","doi-asserted-by":"publisher","first-page":"105171","DOI":"10.1016\/j.neubiorev.2023.105171","volume":"149","author":"ES Kruithof","year":"2023","unstructured":"Kruithof ES, Klaus J, Schutter D. The human cerebellum in reward anticipation and outcome processing: an activation likelihood Estimation meta-analysis. Neurosci Biobehav Rev. 2023;149:105171.","journal-title":"Neurosci Biobehav Rev"},{"issue":"2","key":"1822_CR34","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s00429-011-0365-2","volume":"217","author":"S Kuhn","year":"2012","unstructured":"Kuhn S, Romanowski A, Schubert F, Gallinat J. Reduction of cerebellar grey matter in Crus I and II in schizophrenia. Brain Struct Funct. 2012;217(2):523\u20139.","journal-title":"Brain Struct Funct"},{"key":"1822_CR35","doi-asserted-by":"crossref","unstructured":"Levman J, Kabaria P, Nangaku M, Takahashi E. 2023. Morphological abnormalities in Early-Onset schizophrenia revealed by structural magnetic resonance imaging. Biology (Basel) 12 (3).","DOI":"10.3390\/biology12030353"},{"issue":"5","key":"1822_CR36","doi-asserted-by":"publisher","first-page":"2169","DOI":"10.1007\/s12311-024-01702-0","volume":"23","author":"M Manto","year":"2024","unstructured":"Manto M, Adamaszek M, Apps R, Carlson E, Guarque-Chabrera J, Heleven E, Kakei S, Khodakhah K, Kuo SH, Lin CR, Joshua M, Miquel M, Mitoma H, Larry N, Peron JA, Pickford J, Schutter D, Singh MK, Tan T, Tanaka H, Tsai P, Van Overwalle F, Yamashiro K. Consensus paper: cerebellum and reward. Cerebellum. 2024;23(5):2169\u201392.","journal-title":"Cerebellum"},{"issue":"1\u20132","key":"1822_CR37","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S0920-9964(00)00125-0","volume":"49","author":"M Martin-Loeches","year":"2001","unstructured":"Martin-Loeches M, Molina V, Munoz F, Hinojosa JA, Reig S, Desco M, Benito C, Sanz J, Gabiri A, Sarramea F, Santos A, Palomo T. P300 amplitude as a possible correlate of frontal degeneration in schizophrenia. Schizophr Res. 2001;49(1\u20132):121\u20138.","journal-title":"Schizophr Res"},{"key":"1822_CR38","doi-asserted-by":"crossref","unstructured":"McCutcheon RA, Keefe RSE, McGuire PM, Marquand A. Deconstructing cognitive impairment in psychosis with a machine learning approach. JAMA Psychiatry; 2024.","DOI":"10.1001\/jamapsychiatry.2024.3062"},{"issue":"10","key":"1822_CR39","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1007\/s00234-023-03200-2","volume":"65","author":"L Melazzini","year":"2023","unstructured":"Melazzini L, Mazzocchi L, Vecchio A, Paredes A, Mensi MM, Ballante E, Paoletti M, Bastianello S, Balottin U, Borgatti R, Pichiecchio A. Magnetic resonance advanced imaging analysis in adolescents: cortical thickness study to identify attenuated psychosis syndrome. Neuroradiology. 2023;65(10):1447\u201358.","journal-title":"Neuroradiology"},{"issue":"9","key":"1822_CR40","first-page":"820","volume":"4","author":"T Moberget","year":"2019","unstructured":"Moberget T, Ivry RB. Prediction, psychosis, and the cerebellum. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019;4(9):820\u201331.","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"issue":"1","key":"1822_CR41","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.pscychresns.2004.04.006","volume":"140","author":"V Molina","year":"2005","unstructured":"Molina V, Sanz J, Munoz F, Casado P, Hinojosa JA, Sarramea F, Martin-Loeches M. Dorsolateral prefrontal cortex contribution to abnormalities of the P300 component of the event-related potential in schizophrenia. Psychiatry Res. 2005;140(1):17\u201326.","journal-title":"Psychiatry Res"},{"key":"1822_CR42","doi-asserted-by":"crossref","unstructured":"Morales-Munoz I, Upthegrove R, Mallikarjun PK, Broome MR, Marwaha S. 2021. Longitudinal associations between cognitive deficits in childhood and psychopathological symptoms in adolescence and young adulthood. JAMA Netw Open 4 (4), e214724.","DOI":"10.1001\/jamanetworkopen.2021.4724"},{"issue":"1\u20132","key":"1822_CR43","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S0920-9964(01)00248-1","volume":"55","author":"G Okugawa","year":"2002","unstructured":"Okugawa G, Sedvall G, Nordstrom M, Andreasen N, Pierson R, Magnotta V, Agartz I. Selective reduction of the posterior superior vermis in men with chronic schizophrenia. Schizophr Res. 2002;55(1\u20132):61\u20137.","journal-title":"Schizophr Res"},{"issue":"4","key":"1822_CR44","doi-asserted-by":"publisher","first-page":"147","DOI":"10.7150\/ijms.2.147","volume":"2","author":"SH Patel","year":"2005","unstructured":"Patel SH, Azzam PN. Characterization of N200 and P300: selected studies of the Event-Related potential. Int J Med Sci. 2005;2(4):147\u201354.","journal-title":"Int J Med Sci"},{"key":"1822_CR45","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/jcm10173929","volume":"10","author":"M Rapado-Castro","year":"2021","unstructured":"Rapado-Castro M, Villar-Arenzana M, Janssen J, Fraguas D, Bombin I, Castro-Fornieles J, Mayoral M, Gonzalez-Pinto A, de la Serna E, Parellada M, Moreno D, Paya B, Graell M, Baeza I, Pantelis C, Arango C. Fronto-Parietal Gray matter volume loss is associated with decreased working memory performance in adolescents with a first episode of psychosis. J Clin Med. 2021;10:17.","journal-title":"J Clin Med"},{"issue":"7","key":"1822_CR46","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1001\/archpsyc.56.7.649","volume":"56","author":"JL Rapoport","year":"1999","unstructured":"Rapoport JL, Giedd JN, Blumenthal J, Hamburger S, Jeffries N, Fernandez T, Nicolson R, Bedwell J, Lenane M, Zijdenbos A, Paus T, Evans A. Progressive cortical change during adolescence in childhood-onset schizophrenia. A longitudinal magnetic resonance imaging study. Arch Gen Psychiatry. 1999;56(7):649\u201354.","journal-title":"Arch Gen Psychiatry"},{"issue":"4","key":"1822_CR47","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1016\/j.neuroimage.2010.07.018","volume":"53","author":"PE Rasser","year":"2010","unstructured":"Rasser PE, Schall U, Peck G, Cohen M, Johnston P, Khoo K, Carr VJ, Ward PB, Thompson PM. Cerebellar grey matter deficits in first-episode schizophrenia mapped using cortical pattern matching. NeuroImage. 2010;53(4):1175\u201380.","journal-title":"NeuroImage"},{"key":"1822_CR48","doi-asserted-by":"publisher","first-page":"104322","DOI":"10.1016\/j.nbd.2018.11.007","volume":"131","author":"T Sakurai","year":"2019","unstructured":"Sakurai T, Gamo NJ. Cognitive functions associated with developing prefrontal cortex during adolescence and developmental neuropsychiatric disorders. Neurobiol Dis. 2019;131:104322.","journal-title":"Neurobiol Dis"},{"issue":"7","key":"1822_CR49","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1016\/j.jaac.2023.10.016","volume":"63","author":"G de Salazar","year":"2024","unstructured":"de Salazar G, Rodriguez V, Besana F, Civardi SC, Arienti V, Garceo M, Andres-Camazon L, Catalan P, Rogdaki A, Abbott M, Kyriakopoulos C, Fusar-Poli M, Correll P, Arango CU, C. Umbrella review: atlas of the Meta-Analytical evidence of Early-Onset psychosis. J Am Acad Child Adolesc Psychiatry. 2024;63(7):684\u201397.","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"3","key":"1822_CR50","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1080\/14734220701490995","volume":"6","author":"JD Schmahmann","year":"2007","unstructured":"Schmahmann JD, Weilburg JB, Sherman JC. The neuropsychiatry of the cerebellum - insights from the clinic. Cerebellum. 2007;6(3):254\u201367.","journal-title":"Cerebellum"},{"issue":"4","key":"1822_CR51","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1007\/s11065-018-9388-2","volume":"28","author":"JM Sheffield","year":"2018","unstructured":"Sheffield JM, Karcher NR, Barch DM. Cognitive deficits in psychotic disorders: A lifespan perspective. Neuropsychol Rev. 2018;28(4):509\u201333.","journal-title":"Neuropsychol Rev"},{"issue":"5","key":"1822_CR52","first-page":"438","volume":"2","author":"AK Shinn","year":"2017","unstructured":"Shinn AK, Roh YS, Ravichandran CT, Baker JT, Ongur D, Cohen BM. Aberrant cerebellar connectivity in bipolar disorder with psychosis. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017;2(5):438\u201348.","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"issue":"2","key":"1822_CR53","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1038\/s41380-023-02343-1","volume":"29","author":"S Si","year":"2024","unstructured":"Si S, Bi A, Yu Z, See C, Kelly S, Ambrogi S, Arango C, Baeza I, Banaj N, Berk M, Castro-Fornieles J, Crespo-Facorro B, Crouse JJ, Diaz-Caneja CM, Fett AK, Fortea A, Frangou S, Goldstein BI, Hickie IB, Janssen J, Kennedy KG, Krabbendam L, Kyriakopoulos M, MacIntosh BJ, Morgado P, Nerland S, Pascual-Diaz S, Pico-Perez M, Piras F, Rund BR, de la Serna E, Spalletta G, Sugranyes G, Suo C, Tordesillas-Gutierrez D, Vecchio D, Radua J, McGuire P, Thomopoulos SI, Jahanshad N, Thompson PM, Barth C, Agartz I, James A, Kempton MJ. Mapping Gray and white matter volume abnormalities in early-onset psychosis: an ENIGMA multicenter voxel-based morphometry study. Mol Psychiatry. 2024;29(2):496\u2013504.","journal-title":"Mol Psychiatry"},{"issue":"8","key":"1822_CR54","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1016\/j.neubiorev.2010.01.016","volume":"34","author":"R Smieskova","year":"2010","unstructured":"Smieskova R, Fusar-Poli P, Allen P, Bendfeldt K, Stieglitz RD, Drewe J, Radue EW, McGuire PK, Riecher-Rossler A, Borgwardt SJ. Neuroimaging predictors of transition to psychosis\u2013a systematic review and meta-analysis. Neurosci Biobehav Rev. 2010;34(8):1207\u201322.","journal-title":"Neurosci Biobehav Rev"},{"issue":"9","key":"1822_CR55","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1176\/appi.ajp.157.9.1475","volume":"157","author":"ER Sowell","year":"2000","unstructured":"Sowell ER, Levitt J, Thompson PM, Holmes CJ, Blanton RE, Kornsand DS, Caplan R, McCracken J, Asarnow R, Toga AW. Brain abnormalities in early-onset schizophrenia spectrum disorder observed with statistical parametric mapping of structural magnetic resonance images. Am J Psychiatry. 2000;157(9):1475\u201384.","journal-title":"Am J Psychiatry"},{"key":"1822_CR56","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.schres.2019.02.014","volume":"226","author":"Y Tang","year":"2020","unstructured":"Tang Y, Wang J, Zhang T, Xu L, Qian Z, Cui H, Tang X, Li H, Whitfield-Gabrieli S, Shenton ME, Seidman LJ, McCarley RW, Keshavan MS, Stone WS, Wang J, Niznikiewicz MA. P300 as an index of transition to psychosis and of remission: data from a clinical high risk for psychosis study and review of literature. Schizophr Res. 2020;226:74\u201383.","journal-title":"Schizophr Res"},{"issue":"20","key":"1822_CR57","doi-asserted-by":"publisher","first-page":"11650","DOI":"10.1073\/pnas.201243998","volume":"98","author":"PM Thompson","year":"2001","unstructured":"Thompson PM, Vidal C, Giedd JN, Gochman P, Blumenthal J, Nicolson R, Toga AW, Rapoport JL. Mapping adolescent brain change reveals dynamic wave of accelerated Gray matter loss in very early-onset schizophrenia. Proc Natl Acad Sci U S A. 2001;98(20):11650\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1822_CR58","doi-asserted-by":"publisher","first-page":"111100","DOI":"10.1016\/j.pscychresns.2020.111100","volume":"302","author":"G Tronchin","year":"2020","unstructured":"Tronchin G, Akudjedu TN, Kenney JP, McInerney S, Scanlon C, McFarland J, McCarthy P, Cannon DM, Hallahan B, McDonald C. Cognitive and clinical predictors of prefrontal cortical thickness change following First-Episode of psychosis. Psychiatry Res Neuroimaging. 2020;302:111100.","journal-title":"Psychiatry Res Neuroimaging"},{"key":"1822_CR59","doi-asserted-by":"crossref","unstructured":"Tschentscher N, Woll CFJ, Tafelmaier JC, Kriesche D, Bucher JC, Engel RR, Karch S. 2023. Neurocognitive deficits in First-Episode and chronic psychotic disorders: A systematic review from 2009 to 2022. Brain Sci 13 (2).","DOI":"10.3390\/brainsci13020299"},{"issue":"4","key":"1822_CR60","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1177\/1073858408316002","volume":"14","author":"S Tsujimoto","year":"2008","unstructured":"Tsujimoto S. The prefrontal cortex: functional neural development during early childhood. Neuroscientist. 2008;14(4):345\u201358.","journal-title":"Neuroscientist"},{"issue":"2\u20133","key":"1822_CR61","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.schres.2005.04.024","volume":"77","author":"O van der Stelt","year":"2005","unstructured":"van der Stelt O, Lieberman JA, Belger A. Auditory P300 in high-risk, recent-onset and chronic schizophrenia. Schizophr Res. 2005;77(2\u20133):309\u201320.","journal-title":"Schizophr Res"},{"key":"1822_CR62","doi-asserted-by":"crossref","unstructured":"van Dinteren R, Arns M, Jongsma ML, Kessels RP. 2014. P300 development across the lifespan: a systematic review and meta-analysis. PLoS ONE 9 (2), e87347.","DOI":"10.1371\/journal.pone.0087347"},{"issue":"1","key":"1822_CR63","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/s41386-022-01451-w","volume":"48","author":"S Vinogradov","year":"2023","unstructured":"Vinogradov S, Chafee MV, Lee E, Morishita H. Psychosis spectrum illnesses as disorders of prefrontal critical period plasticity. Neuropsychopharmacology. 2023;48(1):168\u201385.","journal-title":"Neuropsychopharmacology"},{"key":"1822_CR64","doi-asserted-by":"publisher","first-page":"1451832","DOI":"10.3389\/fpsyt.2024.1451832","volume":"15","author":"A Vita","year":"2024","unstructured":"Vita A, Barlati S, Cavallaro R, Mucci A, Riva MA, Rocca P, Rossi A, Galderisi S. Definition, assessment and treatment of cognitive impairment associated with schizophrenia: expert opinion and practical recommendations. Front Psychiatry. 2024;15:1451832.","journal-title":"Front Psychiatry"},{"key":"1822_CR65","doi-asserted-by":"crossref","unstructured":"Ward HB, Beermann A, Xie J, Yildiz G, Felix KM, Addington J, Bearden CE, Cadenhead K, Cannon TD, Cornblatt B, Keshavan M, Mathalon D, Perkins DO, Seidman L, Stone WS, Tsuang MT, Walker EF, Woods S, Coleman MJ, Bouix S, Holt DJ, Ongur D, Breier A, Shenton ME, Heckers S, Halko MA, Lewandowski KE, Brady RO Jr. 2024. Robust Brain Correlates of Cognitive Performance in Psychosis and Its Prodrome. Biol Psychiatry.","DOI":"10.1016\/j.biopsych.2023.02.555"}],"container-title":["The Cerebellum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-025-01822-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12311-025-01822-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-025-01822-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T03:14:37Z","timestamp":1745810077000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12311-025-01822-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,21]]},"references-count":65,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,6]]}},"alternative-id":["1822"],"URL":"https:\/\/doi.org\/10.1007\/s12311-025-01822-1","relation":{},"ISSN":["1473-4230"],"issn-type":[{"value":"1473-4230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,21]]},"assertion":[{"value":"11 March 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dr. Gonzalez-Heydrich holds equity in and is founding head of the scientific advisory board for Mightier\/Neuromotion Labs, a company making emotional regulation training video games and has received consulting income from Alkermes, Sunovion, and Neurocrine pharmaceutical companies. Dr. Upadhyay receives funding support from SanofiGenzyme and the Boston Children\u2019s Hospital CHMC Anesthesia Foundation. All other authors have indicated they have no conflicts of interest relevant to this article to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"69"}}