{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T06:16:52Z","timestamp":1788675412526,"version":"build-2803163510"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cerebellum"],"DOI":"10.1007\/s12311-026-01959-7","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T08:19:59Z","timestamp":1769501999000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Co-occurrence of Neuroleptic Malignant Syndrome and Silent Syndrome in a Patient With Bipolar Disorder: Clinical Challenges and Long-term Neurological Sequelae"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0397-5037","authenticated-orcid":false,"given":"Buse","family":"Ceyran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efruz Pirdogan","family":"Aydin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burce","family":"Yucel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derya Selcuk","family":"Demirelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,27]]},"reference":[{"issue":"3","key":"1959_CR1","doi-asserted-by":"publisher","first-page":"395","DOI":"10.2174\/1570159X13999150424113345","volume":"13","author":"L Tse","year":"2015","unstructured":"Tse L, Barr AM, Scarapicchia V, Vila-Rodriguez F. Neuroleptic malignant syndrome: a review from a clinically oriented perspective. Curr Neuropharmacol. 2015;13(3):395\u2013406. https:\/\/doi.org\/10.2174\/1570159X13999150424113345.","journal-title":"Curr Neuropharmacol"},{"issue":"3","key":"1959_CR2","doi-asserted-by":"publisher","first-page":"175","DOI":"10.34172\/jept.2021.36","volume":"12","author":"A Aggarwal","year":"2022","unstructured":"Aggarwal A. Lithium induced irreversible neurotoxicity at therapeutic levels. J Exp Pharmacol Ther. 2022;12(3):175\u20139. https:\/\/doi.org\/10.34172\/jept.2021.36.","journal-title":"J Exp Pharmacol Ther"},{"key":"1959_CR3","doi-asserted-by":"crossref","unstructured":"3. Adityanjee, Munshi KR, Thampy A. The syndrome of irreversible lithium-effectuated neurotox- icity. Clin Neuropharmacol. 2005;28(1):38\u201349. doi:10.1097\/01.wnf.0000150941.44882.f1","DOI":"10.1097\/01.wnf.0000150871.52253.b7"},{"issue":"11","key":"1959_CR4","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1002\/mds.21544.","volume":"22","author":"A Weyer","year":"2007","unstructured":"Weyer A, Abele M, Schmitz-H\u00fcbsch T, Schoch B, Frings M, Timmann D, et al. Reliability and validity of the scale for the assessment and rating of ataxia: a study in 64 ataxia patients. Mov Disord. 2007;22(11):1633\u20137. https:\/\/doi.org\/10.1002\/mds.21544.","journal-title":"Mov Disord"},{"key":"1959_CR5","doi-asserted-by":"publisher","unstructured":"Berman BD. Neuroleptic Malignant Syndrome: a Review for Neurohospitalists: A Review for Neuro hospitalists. The Neuro hospitalist. 2011;1(1):41\u20137. https:\/\/doi.org\/10.1177\/1941875210386491.","DOI":"10.1177\/1941875210386491"},{"key":"1959_CR6","doi-asserted-by":"publisher","unstructured":"Lam RW, Kennedy SH, Adams C, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 update on clinical guidelines for management of major depressive disorder in adults. Can J Psychiatry. 2024;69(9):1\u201314. https:\/\/doi.org\/10.1177\/07067437231154312","DOI":"10.1177\/07067437231154312"},{"issue":"1","key":"1959_CR7","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-017-1353-0","volume":"17","author":"B Shine","year":"2017","unstructured":"Shine B, McKnight RF, Leaver L, Geddes JR. Permanent cerebellar degeneration after acute hy- perthermia with non-toxic lithium levels: a case report and review of literature. BMC Psychiatry. 2017;17(1):197. https:\/\/doi.org\/10.1186\/s12888-017-1353-0.","journal-title":"BMC Psychiatry"},{"issue":"2","key":"1959_CR8","doi-asserted-by":"publisher","first-page":"190","DOI":"10.5455\/apd.147264","volume":"25","author":"K Konieczny","year":"2024","unstructured":"Konieczny K, Detraux J, Bouckaert F. The syndrome of irreversible lithium-effectuated neuro- toxicity: a scoping review. Alpha Psychiatry. 2024;25(2):190\u20138. https:\/\/doi.org\/10.5455\/apd.147264.","journal-title":"Alpha Psychiatry"},{"issue":"4","key":"1959_CR9","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1177\/0885066616651582.","volume":"32","author":"J Baird-Gunning","year":"2017","unstructured":"Baird-Gunning J, Lea-Henry T, Hoegberg LCG, Gosselin S, Roberts DM. Lithium poisoning. J Intensive Care Med. 2017;32(4):249\u201363. https:\/\/doi.org\/10.1177\/0885066616651582.","journal-title":"J Intensive Care Med"},{"issue":"2","key":"1959_CR10","doi-asserted-by":"publisher","first-page":"72","DOI":"10.4414\/sanp.2011.02249","volume":"162","author":"H Boeker","year":"2011","unstructured":"Boeker H, Seidl A, Schopper C. Neurotoxicity related to combined treatment with lithium, antidepressants and atypical antipsychotics: A series of cases. Swiss Arch Neurol Psychiatr. 2011;162(2):72\u20136.","journal-title":"Swiss Arch Neurol Psychiatr"},{"issue":"2","key":"1959_CR11","doi-asserted-by":"publisher","first-page":"104","DOI":"10.14744\/DAJPNS.2025.00280","volume":"38","author":"A Alp","year":"2025","unstructured":"Alp A, \u00d6z\u00e7elik-Ero\u011flu E. Neuroleptic malignant syndrome occurring with amisulpride after lithium toxicity in a patient. Dusunen Adam J Psychiatry Neurol Sci. 2025;38(2):104\u20136.","journal-title":"Dusunen Adam J Psychiatry Neurol Sci"},{"issue":"1","key":"1959_CR12","first-page":"18","volume":"10","author":"H Tharoor","year":"2007","unstructured":"Tharoor H, Deora S, Chauhan A, Sharma PSVN. Lithium\u2013neuroleptic combination leading to permanent neurological sequelae. Ger J Psychiatry. 2007;10(1):18\u201320.","journal-title":"Ger J Psychiatry"},{"issue":"2","key":"1959_CR13","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1097\/WNF.0000000000000417","volume":"44","author":"SY Rhee","year":"2021","unstructured":"Rhee SY, Kim HS. Subcortical structure disruption in diffusion tensor tractography of the pa- tient with the syndrome of irreversible lithium-effectuated neurotoxicity combined with neuroleptic malignant syndrome: A case report. Clin Neuropharmacol. 2021;44(2):62\u20137. https:\/\/doi.org\/10.1097\/WNF.0000000000000417.","journal-title":"Clin Neuropharmacol"},{"issue":"12","key":"1959_CR14","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1007\/s40263-014-0207-y","volume":"28","author":"J Van Gaalen","year":"2014","unstructured":"Van Gaalen J, Kerstens FG, Maas RPPWM, H\u00e4rmark L, van de Warrenburg BPC. Drug-in- duced cerebellar ataxia: A systematic review. CNS Drugs. 2014;28(12):1139\u201353. https:\/\/doi.org\/10.1007\/s40263-014-0207-y.","journal-title":"CNS Drugs"},{"issue":"10","key":"1959_CR15","doi-asserted-by":"publisher","first-page":"669","DOI":"10.2165\/00023210-200216100-00003","volume":"16","author":"W L\u00f6scher","year":"2002","unstructured":"L\u00f6scher W. Basic pharmacology of valproate: A review after 35 years of clinical use for the treatment of epilepsy. CNS Drugs. 2002;16(10):669\u201394. https:\/\/doi.org\/10.2165\/00023210-200216100-00003.","journal-title":"CNS Drugs"}],"container-title":["The Cerebellum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-026-01959-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12311-026-01959-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-026-01959-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T10:35:50Z","timestamp":1772015750000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12311-026-01959-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,27]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2]]}},"alternative-id":["1959"],"URL":"https:\/\/doi.org\/10.1007\/s12311-026-01959-7","relation":{},"ISSN":["1473-4230"],"issn-type":[{"value":"1473-4230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,27]]},"assertion":[{"value":"25 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"13"}}