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This research was conducted in accordance with the Declaration of Helsinki. The identified DNA samples and associated clinical data were obtained through the Neurogenetics DNA Bank, and therefore, no direct contact with study participants occurred. All sample donors had previously provided written informed consent authorizing the use of their genetic and clinical data for anonymized ongoing and future research studies. This study was not designed or conducted as a clinical trial. The open-label use of medication in a patient with SCA27B was undertaken as part of individual clinical care and did not constitute a prospective interventional study. We confirm that we have read the Journal\u2019s position on issues involved in ethical publication and affirm that this work is consistent with those guidelines.","order":1,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"157"}}