{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T07:07:26Z","timestamp":1776755246735,"version":"3.51.2"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T00:00:00Z","timestamp":1461801600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Science and Technology Foundation of Guangdong Province of China","award":["2014A020212714"],"award-info":[{"award-number":["2014A020212714"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s12325-016-0330-9","type":"journal-article","created":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T16:50:16Z","timestamp":1461862216000},"page":"760-773","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Boston Keratoprosthesis Outcomes in Severe Ocular Chemical Burns in Southern China: A Retrospective Study"],"prefix":"10.1007","volume":"33","author":[{"given":"Jianjun","family":"Gu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajie","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,4,28]]},"reference":[{"key":"330_CR1","first-page":"97","volume":"81","author":"SG Kramer","year":"1983","unstructured":"Kramer SG. Late numerical grading of alkali burns to determine keratoplasty prognosis. Trans Am Ophthalmol Soc. 1983;81:97\u2013106.","journal-title":"Trans Am Ophthalmol Soc"},{"issue":"4","key":"330_CR2","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0039-6257(96)00007-0","volume":"41","author":"MD Wagoner","year":"1997","unstructured":"Wagoner MD. Chemical injuries of the eye: current concepts in pathophysiology and therapy. Surv Ophthalmol. 1997;41(4):275\u2013313.","journal-title":"Surv Ophthalmol."},{"issue":"6","key":"330_CR3","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.ajo.2011.05.019","volume":"152","author":"S Basu","year":"2011","unstructured":"Basu S, Mohamed A, Chaurasia S, et al. Clinical outcomes of penetrating keratoplastyafterautologouscultivatedlimbalepithelialtransplantation for ocular surface burns. Am J Ophthalmol. 2011;152(6):917\u201324.","journal-title":"Am J Ophthalmol"},{"key":"330_CR4","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1038\/eye.2008.414","volume":"23","author":"SJ Tuft","year":"2009","unstructured":"Tuft SJ, Shortt AJ. Surgical rehabilitation following severe ocular burns. Eye (Lond). 2009;23:1966\u201371.","journal-title":"Eye (Lond)"},{"key":"330_CR5","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1001\/archophthalmol.2009.263","volume":"127","author":"L Liang","year":"2009","unstructured":"Liang L, Sheha H, Tseng SC. Long-term outcomes of keratolimbal allograft for total limbal stem cell deficiency using combined immunosuppressive agents and correction of ocular surface deficits. Arch Ophthalmol. 2009;127:1428\u201334.","journal-title":"Arch Ophthalmol"},{"key":"330_CR6","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.ophtha.2008.12.058","volume":"116","author":"AJ Aldave","year":"2009","unstructured":"Aldave AJ, Kamal KM, Vo RC, et al. The Boston type I keratoprosthesis: improving outcomes and expanding indications. Ophthalmology. 2009;116:640\u201351.","journal-title":"Ophthalmology"},{"key":"330_CR7","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3129\/i08-009","volume":"43","author":"M Harissi-Dagher","year":"2008","unstructured":"Harissi-Dagher M, Dohlman CH. The Boston keratoprosthesis in severe ocular trauma. Can J Ophthalmol. 2008;43:165\u20139.","journal-title":"Can J Ophthalmol"},{"key":"330_CR8","first-page":"537","volume":"48","author":"JQ Chen","year":"2012","unstructured":"Chen JQ, Zhai JJ, Gu JJ, et al. Preliminary study of Boston keratoprosthesis in treatment of severe late stage ocular chemical burns. Zhonghua Yan KezaZhi. 2012;48:537\u201341.","journal-title":"Zhonghua Yan KezaZhi."},{"key":"330_CR9","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1097\/ICO.0b013e31823f8e95","volume":"31","author":"CC Chan","year":"2012","unstructured":"Chan CC, Biber JM, Holland EJ. The modified Cincinnati procedure: combined conjunctival limbal autografts and keratolimbal allografts for severe unilateral ocular surface failure. Cornea. 2012;31:1264\u201372.","journal-title":"Cornea"},{"key":"330_CR10","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jcrs.2004.01.014","volume":"30","author":"JT Holladay","year":"2004","unstructured":"Holladay JT. Visual acuity measurements. J Cataract Refract Surg. 2004;30:287\u201390.","journal-title":"J Cataract Refract Surg"},{"key":"330_CR11","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1136\/bjo.2007.130567","volume":"92","author":"C Liu","year":"2008","unstructured":"Liu C, Okera S, Tandon R, et al. Visual rehabilitation in end-stage inflammatory ocular surface disease with the osteo-odonto-keratoprosthesis: results from the UK. Br J Ophthalmol. 2008;92:1211\u20137.","journal-title":"Br J Ophthalmol"},{"key":"330_CR12","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1586\/17469899.1.1.41","volume":"1","author":"CH Dohlman","year":"2006","unstructured":"Dohlman CH, Harissi-Dagher M. Introduction to the use of the Boston keratoprosthesis. Expet Rev Ophthalmol. 2006;1:41\u20138.","journal-title":"Expet Rev Ophthalmol."},{"key":"330_CR13","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/j.ophtha.2010.12.032","volume":"118","author":"MA Greiner","year":"2011","unstructured":"Greiner MA, Li JY, Mannis MJ. Longer-term vision outcomes and complications with the Boston type 1 keratoprosthesis at the University of California, Davis. Ophthalmology. 2011;118:1543\u201350.","journal-title":"Ophthalmology."},{"key":"330_CR14","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1097\/ICO.0b013e31821eead6","volume":"30","author":"F Cade","year":"2011","unstructured":"Cade F, Grosskreutz CL, Tauber A, et al. Glaucoma in eyes with severe chemical burn, before and after keratoprosthesis. Cornea. 2011;30:1322\u20137.","journal-title":"Cornea"},{"key":"330_CR15","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/eye.2011.325","volume":"26","author":"AP Patel","year":"2012","unstructured":"Patel AP, Wu EI, Ritterband DC, et al. Boston type 1 keratoprosthesis: the New York eye and ear experience. Eye (Lond). 2012;26:418\u201325.","journal-title":"Eye (Lond)."},{"key":"330_CR16","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/ICO.0b013e31820f7a32","volume":"31","author":"R Kamyar","year":"2012","unstructured":"Kamyar R, Weizer JS, de Paula FH, et al. Glaucoma associated with Boston type I keratoprosthesis. Cornea. 2012;31:134\u20139.","journal-title":"Cornea"},{"key":"330_CR17","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1097\/ICO.0b013e3182012a4f","volume":"30","author":"CH Dohlman","year":"2011","unstructured":"Dohlman CH, Cade F, Pfister R. Chemical burns to the eye: paradigm shifts in treatment. Cornea. 2011;30:613\u20134.","journal-title":"Cornea"},{"key":"330_CR18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/IJG.0b013e3181a2fbeb","volume":"19","author":"CH Dohlman","year":"2010","unstructured":"Dohlman CH, Grosskreutz CL, Chen TC, et al. Shunts to divert aqueous humor to distant epithelialized cavities after keratoprosthesis surgery. J Glaucoma. 2010;19:111\u20135.","journal-title":"J Glaucoma"},{"key":"330_CR19","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ajo.2011.01.034","volume":"152","author":"JY Li","year":"2011","unstructured":"Li JY, Greiner MA, Brandt JD, et al. Long-term complications associated with glaucoma drainage devices and Boston keratoprosthesis. Am J Ophthalmol. 2011;152:209\u201318.","journal-title":"Am J Ophthalmol"},{"key":"330_CR20","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/IJG.0b013e3181815485","volume":"18","author":"D Rivier","year":"2009","unstructured":"Rivier D, Paula JS, Kim E, et al. Glaucoma and keratoprosthesis surgery: role of adjunctive cyclophotocoagulation. J Glaucoma. 2009;18:321\u20134.","journal-title":"J Glaucoma"},{"issue":"11","key":"330_CR21","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.ophtha.2004.05.027","volume":"111","author":"P Lin","year":"2004","unstructured":"Lin P, Wollstein G, Glavas IP, et al. Contact transscleral neodymium: yttrium-aluminum-garnet laser cyclophotocoagulation Long-term outcome. Ophthalmology. 2004;111(11):2137\u201343.","journal-title":"Ophthalmology."},{"issue":"4","key":"330_CR22","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1136\/bjophthalmol-2014-306396","volume":"100","author":"LL Kammerdiener","year":"2016","unstructured":"Kammerdiener LL, Speiser JL, Aquavella JV, et al. Protective effect of soft contact lenses after Boston keratoprosthesis. Br J Ophthalmol. 2016;100(4):549\u201352.","journal-title":"Br J Ophthalmol"},{"key":"330_CR23","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s00417-012-1960-5","volume":"250","author":"L Kiang","year":"2012","unstructured":"Kiang L, Rosenblatt MI, Sartaj R, et al. Surface epithelialization of the type I Boston keratoprosthesis front plate: immunohistochemical and high-definition optical coherence tomography characterization. Graefes Arch Clin Exp Ophthalmol. 2012;250:1195\u20139.","journal-title":"Graefes Arch Clin Exp Ophthalmol."},{"key":"330_CR24","first-page":"1069","volume":"4","author":"YM Khalifa","year":"2010","unstructured":"Khalifa YM, Davis D, Mamalis N, et al. Epithelial growth over the optic surface of the type 1 Boston Keratoprosthesis: histopathology and implications for biointegration. Clin Ophthalmol. 2010;4:1069\u201371.","journal-title":"Clin Ophthalmol."},{"key":"330_CR25","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.ajo.2009.11.001","volume":"149","author":"JD Ament","year":"2010","unstructured":"Ament JD, Todani A, Pineda R 2nd, et al. Global corneal blindness and the Boston keratoprosthesis type I. Am J Ophthalmol. 2010;149:537\u20139.","journal-title":"Am J Ophthalmol"},{"key":"330_CR26","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/ICO.0b013e31823e6110","volume":"31","author":"M Robert","year":"2012","unstructured":"Robert M, Biernacki K, Harissi-Dagher M. Boston keratoprosthesis type 1 surgery: use of frozen versus fresh corneal donor carriers. Cornea. 2012;31:339\u201345.","journal-title":"Cornea"},{"key":"330_CR27","doi-asserted-by":"crossref","first-page":"e491","DOI":"10.1016\/j.ajo.2012.03.022","volume":"154","author":"EK Akpek","year":"2012","unstructured":"Akpek EK, Aldave AJ, Aquavella JV. The use of precut, gamma-irradiated corneal lenticules in Boston type 1 keratoprosthesis implantation. Am J Ophthalmol. 2012;154:e491.","journal-title":"Am J Ophthalmol"},{"key":"330_CR28","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1001\/archophthalmol.2010.79","volume":"128","author":"JD Ament","year":"2010","unstructured":"Ament JD, Tilahun Y, Mudawi E, et al. Role for ipsilateral autologous corneas as a carrier for the Boston keratoprosthesis: the Africa experience. Arch Ophthalmol. 2010;128:795\u20137.","journal-title":"Arch Ophthalmol"},{"key":"330_CR29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/686587","volume":"2013","author":"A Cruzat","year":"2013","unstructured":"Cruzat A, Tauber A, Shukla A, et al. Low-cost and readily available tissue carriers for the Boston keratoprosthesis: a review of possibilities. J Ophthalmol. 2013;2013:1\u20135.","journal-title":"J Ophthalmol."},{"key":"330_CR30","first-page":"104","volume":"45","author":"J Yuan","year":"2009","unstructured":"Yuan J, Chen JQ, Zhou SY, et al. The effects of transplantation of compound keratoprosthesis in clinical practice and managements of complications after operation. Zhonghua Yan Ke Za Zhi. 2009;45:104\u20139.","journal-title":"Zhonghua Yan Ke Za Zhi."},{"key":"330_CR31","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/978-3-642-55179-6_19","volume-title":"Keratoprostheses and artificial corneas","author":"Sotiria Palioura","year":"2015","unstructured":"Palioura Sotiria, Chodosh James. Boston keratoprosthesis type II: indications, techniques, outcomes, and management. In: Cortina M, Cruz J, editors. Keratoprostheses and artificial corneas. Heidelberg: Springer; 2015. p. 169\u201380."},{"key":"330_CR32","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1001\/archopht.119.3.345","volume":"113","author":"PR Egbert","year":"2001","unstructured":"Egbert PR, Fiadoyor S, Budenz DL, et al. Diode laser transscleral cyclophotocoagulation as a primary surgical treatment for primary open-angle glaucoma. Arch Ophthalmol. 2001;113:345\u201350.","journal-title":"Arch Ophthalmol"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-016-0330-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12325-016-0330-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-016-0330-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T20:29:27Z","timestamp":1692304167000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12325-016-0330-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,28]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["330"],"URL":"https:\/\/doi.org\/10.1007\/s12325-016-0330-9","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,28]]}}}