{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T18:07:19Z","timestamp":1776276439738,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"10","funder":[{"name":"Papageorgiou General Hospital, Thessaloniki"},{"name":"North Greece Association of Diabetes"},{"name":"Foundation AGIR pour les Maladies Chroniques"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1007\/s12325-016-0399-1","type":"journal-article","created":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T11:03:51Z","timestamp":1471950231000},"page":"1840-1847","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Diabetic Peripheral Neuropathy as a Predictor of Asymptomatic Myocardial Ischemia in Type 2 Diabetes Mellitus: A Cross-Sectional Study"],"prefix":"10.1007","volume":"33","author":[{"given":"Dimitrios","family":"Baltzis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthieu","family":"Roustit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria G.","family":"Grammatikopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Katsaboukas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vassileios","family":"Athanasiou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Iakovou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aristidis","family":"Veves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos","family":"Manes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria-Christina","family":"Trakatelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,23]]},"reference":[{"issue":"Suppl 1","key":"399_CR1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/dmrr.2694","volume":"32","author":"K Bakker","year":"2016","unstructured":"Bakker K, Apelqvist J, Lipsky BA, Van Netten JJ, International Working Group on the Diabetic F. The 2015 IWGDF guidance documents on prevention and management of foot problems in diabetes: development of an evidence-based global consensus. Diabetes Metab Res Rev. 2016;32(Suppl 1):2\u20136.","journal-title":"Diabetes Metab Res Rev."},{"issue":"11","key":"399_CR2","doi-asserted-by":"crossref","first-page":"2906","DOI":"10.1007\/s00125-012-2673-3","volume":"55","author":"JR Brownrigg","year":"2012","unstructured":"Brownrigg JR, Davey J, Holt PJ, Davis WA, Thompson MM, Ray KK, et al. The association of ulceration of the foot with cardiovascular and all-cause mortality in patients with diabetes: a meta-analysis. Diabetologia. 2012;55(11):2906\u201312.","journal-title":"Diabetologia"},{"issue":"8","key":"399_CR3","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1056\/NEJMra061889","volume":"356","author":"PG Camici","year":"2007","unstructured":"Camici PG, Crea F. Coronary microvascular dysfunction. N Engl J Med. 2007;356(8):830\u201340.","journal-title":"N Engl J Med"},{"issue":"8","key":"399_CR4","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.2337\/diacare.27.8.1954","volume":"27","author":"FJ Wackers","year":"2004","unstructured":"Wackers FJ, Young LH, Inzucchi SE, Chyun DA, Davey JA, Barrett EJ, et al. Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study. Diabetes Care. 2004;27(8):1954\u201361.","journal-title":"Diabetes Care"},{"issue":"7","key":"399_CR5","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.2337\/dc10-0125","volume":"33","author":"R Pop-Busui","year":"2010","unstructured":"Pop-Busui R, Evans GW, Gerstein HC, Fonseca V, Fleg JL, Hoogwerf BJ, et al. Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes Care. 2010;33(7):1578\u201384.","journal-title":"Diabetes Care"},{"issue":"23","key":"399_CR6","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1136\/heartjnl-2014-305657","volume":"100","author":"JR Brownrigg","year":"2014","unstructured":"Brownrigg JR, de Lusignan S, McGovern A, Hughes C, Thompson MM, Ray KK, et al. Peripheral neuropathy and the risk of cardiovascular events in type 2 diabetes mellitus. Heart. 2014;100(23):1837\u201343.","journal-title":"Heart"},{"issue":"4","key":"399_CR7","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1056\/NEJMoa032782","volume":"352","author":"S Tesfaye","year":"2005","unstructured":"Tesfaye S, Chaturvedi N, Eaton SE, Ward JD, Manes C, Ionescu-Tirgoviste C, et al. Vascular risk factors and diabetic neuropathy. N Engl J Med. 2005;352(4):341\u201350.","journal-title":"N Engl J Med"},{"issue":"2","key":"399_CR8","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2337\/diaclin.33.2.97","volume":"33","author":"American Diabetes A","year":"2015","unstructured":"American Diabetes A. Standards of medical care in diabetes\u20142015 abridged for primary care providers. Clin Diabetes. 2015;33(2):97\u2013111.","journal-title":"Clin Diabetes."},{"issue":"2","key":"399_CR9","first-page":"204","volume":"46","author":"WD Leslie","year":"2005","unstructured":"Leslie WD, Tully SA, Yogendran MS, Ward LM, Nour KA, Metge CJ. Prognostic value of automated quantification of 99mTc-sestamibi myocardial perfusion imaging. J Nucl Med. 2005;46(2):204\u201311.","journal-title":"J Nucl Med"},{"issue":"12","key":"399_CR10","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1007\/s00259-015-3139-x","volume":"42","author":"HJ Verberne","year":"2015","unstructured":"Verberne HJ, Acampa W, Anagnostopoulos C, Ballinger J, Bengel F, De Bondt P, et al. EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT\/CT: 2015 revision. Eur J Nucl Med Mol Imaging. 2015;42(12):1929\u201340.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"5","key":"399_CR11","doi-asserted-by":"crossref","first-page":"606","DOI":"10.2337\/diacare.23.5.606","volume":"23","author":"H Pham","year":"2000","unstructured":"Pham H, Armstrong DG, Harvey C, Harkless LB, Giurini JM, Veves A. Screening techniques to identify people at high risk for diabetic foot ulceration: a prospective multicenter trial. Diabetes Care. 2000;23(5):606\u201311.","journal-title":"Diabetes Care"},{"key":"399_CR12","doi-asserted-by":"crossref","unstructured":"American Diabetes Association. Standards of medical care in diabetes\u20142015 abridged for primary care providers. Clin Diabetes 2015;33(2):97\u2013111.","DOI":"10.2337\/diaclin.33.2.97"},{"issue":"24","key":"399_CR13","doi-asserted-by":"crossref","first-page":"2890","DOI":"10.1161\/CIR.0b013e318276fbcb","volume":"126","author":"V Aboyans","year":"2012","unstructured":"Aboyans V, Criqui MH, Abraham P, Allison MA, Creager MA, Diehm C, et al. Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association. Circulation. 2012;126(24):2890\u2013909.","journal-title":"Circulation"},{"key":"399_CR14","doi-asserted-by":"crossref","unstructured":"Roustit M, Loader J, Deusenbery C, Baltzis D, Veves A. Endothelial dysfunction as a link between cardiovascular risk factors and peripheral neuropathy in diabetes. J Clin Endocrinol Metab. 2016:jc20162030 [Epub ahead of print].","DOI":"10.1210\/jc.2016-2030"},{"issue":"10","key":"399_CR15","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrneurol.2011.137","volume":"7","author":"AM Vincent","year":"2011","unstructured":"Vincent AM, Callaghan BC, Smith AL, Feldman EL. Diabetic neuropathy: cellular mechanisms as therapeutic targets. Nat Rev Neurol. 2011;7(10):573\u201383.","journal-title":"Nat Rev Neurol."},{"issue":"6","key":"399_CR16","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1177\/147323000203000602","volume":"30","author":"NK Chammas","year":"2002","unstructured":"Chammas NK, Hill RL, Foster AV, Edmonds ME. Is neuropathic ulceration the key to understanding increased mortality due to ischaemic heart disease in diabetic foot ulcer patients? A population approach using a proportionate model. J Int Med Res. 2002;30(6):553\u20139.","journal-title":"J Int Med Res"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-016-0399-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T21:49:22Z","timestamp":1568324962000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12325-016-0399-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,23]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["399"],"URL":"https:\/\/doi.org\/10.1007\/s12325-016-0399-1","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,23]]}}}