{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,20]],"date-time":"2024-04-20T07:45:34Z","timestamp":1713599134628},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2019,3,30]],"date-time":"2019-03-30T00:00:00Z","timestamp":1553904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s12325-019-00937-2","type":"journal-article","created":{"date-parts":[[2019,3,30]],"date-time":"2019-03-30T20:03:32Z","timestamp":1553976212000},"page":"1243-1245","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Response to \u201cA Rigorous Evaluation of Methoxyflurane is Needed: Comment on \u2018Methoxyflurane Versus Standard of Care for Acute Trauma-Related Pain in the Emergency Setting: Protocol for a Randomised, Controlled Study in Italy (MEDITA)\u2019\u201d"],"prefix":"10.1007","volume":"36","author":[{"given":"Andrea","family":"Fabbri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Carpinteri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germana","family":"Ruggiano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Bonafede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Sblendido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Farina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amedeo","family":"Soldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,30]]},"reference":[{"issue":"1","key":"937_CR1","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1007\/s12325-018-0830-x","volume":"36","author":"A Fabbri","year":"2019","unstructured":"Fabbri A, Carpinteri G, Ruggiano G, Bonafede E, Sblendido A, Farina A, Soldi A, MEDITA Study Group. Methoxyflurane versus standard of care for acute trauma-related pain in the emergency setting: protocol for a randomised, controlled study in Italy (MEDITA). Adv Ther. 2019;36(1):244\u201356.","journal-title":"Adv Ther."},{"issue":"8","key":"937_CR2","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1136\/emermed-2013-202909","volume":"31","author":"F Coffey","year":"2014","unstructured":"Coffey F, Wright J, Hartshorn S, Hunt P, Locker T, Mirza K, Dissmann P. STOP!: a randomised, double-blind, placebo-controlled study of the efficacy and safety of methoxyflurane for the treatment of acute pain. Emerg Med J. 2014;31(8):613\u20138.","journal-title":"Emerg Med J."},{"key":"937_CR3","first-page":"e0008","volume":"1","author":"AM Borobia Pe\u00b4rez","year":"2017","unstructured":"Borobia Pe\u00b4rez AM, Capilla Pueyo R, Casal Codesido JR, InMEDIATE Group, et al. Phase IIIb, open label randomised clinical trial to compare pain relief between methoxyflurane and standard of care for treating patients with trauma pain in Spanish Emergency Units (InMEDIATE): study protocol. IBJ Clin Pharmacol. 2017;1:e0008.","journal-title":"IBJ Clin Pharmacol."},{"issue":"Suppl. 4","key":"937_CR4","first-page":"16","volume":"123","author":"A Borobia P\u00e9rez","year":"2018","unstructured":"Borobia P\u00e9rez A, Garc\u00eda Collado S, Carballo Cardona C, Capilla Pueyo R, Fern\u00e1ndez Alonso C, P\u00e9rez Torres I, et al. InMEDIATE: results of a phase IIIB, open label randomised clinical trial to compare pain relief between methoxyflurane and standard of care analgesia for treating patients with trauma pain in Spanish emergency departments. Basic Clin Pharmacol Toxicol. 2018;123(Suppl. 4):16.","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"937_CR5","unstructured":"Efficacy and Safety of Penthrox\u00ae Combined With a Standard Analgesia (SoC) in Adult Patients Admitted to the Emergency Department With Moderate to Severe Pain Associated With Trauma (Pen ASAP). NCT03798899. \n                    https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03798899?term=methoxyflurane&rank=8\n                    \n                  . Accessed 26 Feb 2019."},{"key":"937_CR6","unstructured":"Raccomandazioni Intersocietarie Italiane (SIAARTI, SIMEU, SIS 118, AISD, SIARED, SICUT, IRC) sulla gestione del dolore in emergenza. 2014. \n                    http:\/\/www.aisd.it\/e107_files\/downloads\/raccintersocietarie_it_complete31052014.pdf\n                    \n                   Accessed 26 Feb 2019."},{"key":"937_CR7","unstructured":"Penthrox\u00ae summary of product characteristics. 2016. \n                    https:\/\/www.medicines.org.uk\/emc\/medicine\/31391\n                    \n                  . Accessed 26 Feb 2019."}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-019-00937-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12325-019-00937-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-019-00937-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,29]],"date-time":"2020-03-29T00:10:53Z","timestamp":1585440653000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12325-019-00937-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,30]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["937"],"URL":"https:\/\/doi.org\/10.1007\/s12325-019-00937-2","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,30]]},"assertion":[{"value":"26 February 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2019","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}