{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:42:10Z","timestamp":1783615330811,"version":"3.55.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,2,15]],"date-time":"2020-02-15T00:00:00Z","timestamp":1581724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2020,2,15]],"date-time":"2020-02-15T00:00:00Z","timestamp":1581724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"The National Key R&D Program of China","award":["2016YFC 1000807"],"award-info":[{"award-number":["2016YFC 1000807"]}]},{"name":"The National Key R&D Program of China","award":["2016YFC 1000801"],"award-info":[{"award-number":["2016YFC 1000801"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s12325-020-01254-9","type":"journal-article","created":{"date-parts":[[2020,2,15]],"date-time":"2020-02-15T17:02:51Z","timestamp":1581786171000},"page":"1425-1435","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Use of Acellular Dermal Matrix for Urethroplasty Coverage in Proximal Hypospadias Repair: a Pilot Study"],"prefix":"10.1007","volume":"37","author":[{"given":"Defu","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guannan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongcheng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanchao","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuofan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yannan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3443-6991","authenticated-orcid":false,"given":"Ning","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,15]]},"reference":[{"key":"1254_CR1","doi-asserted-by":"publisher","first-page":"2498","DOI":"10.1016\/j.jpedsurg.2018.08.010","volume":"53","author":"YS Wong","year":"2018","unstructured":"Wong YS, Tam YH, Pang KKY, Yau HC. Incidence and diagnoses of disorders of sex development in proximal hypospadias. J. Pediatr. Surg. 2018;53:2498\u2013501.","journal-title":"J Pediatr Surg"},{"key":"1254_CR2","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/S0094-0143(02)00026-5","volume":"29","author":"AB Retik","year":"2002","unstructured":"Retik AB, Atala A. Complications of hypospadias repair. Urol Clin North Am. 2002;29:329\u201339.","journal-title":"Urol Clin North Am"},{"key":"1254_CR3","doi-asserted-by":"publisher","first-page":"241","DOI":"10.4103\/0970-1591.40622","volume":"24","author":"A Bhat","year":"2008","unstructured":"Bhat A, Mandal AK. Acute postoperative complications of hypospadias repair. Indian J Urol. 2008;24:241\u20138.","journal-title":"Indian J Urol"},{"key":"1254_CR4","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1159\/000288226","volume":"84","author":"A Yildiz","year":"2010","unstructured":"Yildiz A, Bakan V. Comparison of perimeatal-based flap and tubularized incised plate urethroplasty combined with single- or double-layer dartos flap in distal hypospadias. Urol Int. 2010;84:265\u20138.","journal-title":"Urol Int"},{"key":"1254_CR5","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1007\/s00383-016-3860-y","volume":"32","author":"W Jia","year":"2016","unstructured":"Jia W, Liu G, Zhang L, et al. Comparison of tubularized incised plate urethroplasty combined with a meatus-based ventral dartos flap or dorsal dartos flap in hypospadias. Pediatr. Surg. Int. 2016;32:411\u20135.","journal-title":"Pediatr Surg Int"},{"key":"1254_CR6","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1016\/j.juro.2007.11.101","volume":"179","author":"AW el-Kassaby","year":"2008","unstructured":"el-Kassaby AW, AbouShwareb T, Atala A. Randomized comparative study between buccal mucosal and acellular bladder matrix grafts in complex anterior urethral strictures. J. Urol. 2008;179:1432\u20136.","journal-title":"J Urol"},{"key":"1254_CR7","doi-asserted-by":"publisher","first-page":"4251","DOI":"10.1016\/j.biomaterials.2007.05.020","volume":"28","author":"SY Chun","year":"2007","unstructured":"Chun SY, Lim GJ, Kwon TG, et al. Identification and characterization of bioactive factors in bladder submucosa matrix. Biomaterials. 2007;28:4251\u20136.","journal-title":"Biomaterials"},{"key":"1254_CR8","doi-asserted-by":"publisher","first-page":"4223","DOI":"10.1074\/jbc.M110709200","volume":"277","author":"GA Di Lullo","year":"2002","unstructured":"Di Lullo GA, Sweeney SM, Korkko J, et al. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. J Biol Chem. 2002;277:4223.","journal-title":"J Biol Chem"},{"key":"1254_CR9","doi-asserted-by":"crossref","unstructured":"Jiang P, Tang X, Wang H, et al. Collagen-binding basic fibroblast growth factor improves functional remodeling of scarred endometrium in uterine infertile women: a pilot study. Sci China Life Sci. 2019;62:1617\u201329.","DOI":"10.1007\/s11427-018-9520-2"},{"key":"1254_CR10","doi-asserted-by":"publisher","first-page":"031001","DOI":"10.1088\/1748-6041\/11\/3\/031001","volume":"11","author":"X Hou","year":"2016","unstructured":"Hou X, Shi C, Chen W, et al. Transplantation of human adipose-derived mesenchymal stem cells on a bladder acellular matrix for bladder regeneration in a canine model. Biomed Mater. 2016;11:031001.","journal-title":"Biomed Mater"},{"key":"1254_CR11","doi-asserted-by":"publisher","first-page":"3238","DOI":"10.1016\/j.biomaterials.2006.01.055","volume":"27","author":"Y Sumita","year":"2006","unstructured":"Sumita Y, Honda MJ, Ohara T, et al. Performance of collagen sponge as a 3-D scaffold for tooth tissue engineering. Biomaterials. 2006;27:3238.","journal-title":"Biomaterials"},{"issue":"21\u201322","key":"1254_CR12","first-page":"2739","volume":"17","author":"G Jian","year":"2011","unstructured":"Jian G, Jianzhou L, Yuan G, et al. A myocardial patch made of collagen membranes loaded with collagen-binding human vascular endothelial growth factor accelerates healing of the injured rabbit heart. Tissue Eng Part A. 2011;17(21\u201322):2739\u201347.","journal-title":"Tissue Eng Part A"},{"key":"1254_CR13","doi-asserted-by":"publisher","first-page":"2432","DOI":"10.1016\/j.juro.2010.02.042","volume":"183","author":"W Chen","year":"2010","unstructured":"Chen W, Shi C, Yi S, et al. Bladder regeneration by collagen scaffolds with collagen binding human basic fibroblast growth factor. J Urol. 2010;183:2432\u20139.","journal-title":"J Urol"},{"key":"1254_CR14","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1111\/iju.13912","volume":"26","author":"AY Mahmoud","year":"2019","unstructured":"Mahmoud AY, Gouda S, Gamaan I, Baky F, Mohamed A. Autologous platelet-rich plasma covering urethroplasty versus dartos flap in distal hypospadias repair: a prospective randomized study. Int J Urol. 2019;26:475\u201380.","journal-title":"Int J Urol"},{"key":"1254_CR15","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1016\/j.biomaterials.2006.10.005","volume":"28","author":"F Bolland","year":"2007","unstructured":"Bolland F, Korossis S, Wilshaw S-P, et al. Development and characterisation of a full-thickness acellular porcine bladder matrix for tissue engineering. Biomaterials. 2007;28:1061\u201370.","journal-title":"Biomaterials"},{"issue":"13","key":"1254_CR16","doi-asserted-by":"publisher","first-page":"2814","DOI":"10.1096\/fasebj.5.13.1916105","volume":"5","author":"M Van der Rest","year":"1991","unstructured":"Van der Rest M, Garrone R. Collagen family of proteins. FASEB J. 1991;5(13):2814\u201323.","journal-title":"FASEB J"},{"key":"1254_CR17","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1016\/j.jsxm.2019.09.010","volume":"16","author":"T Xu","year":"2019","unstructured":"Xu T, Zhang G, Bai W, et al. Complications and management of penile girth enhancement with acellular dermal matrix. J Sex Med. 2019;16:2011\u20137.","journal-title":"J Sex Med"},{"key":"1254_CR18","doi-asserted-by":"publisher","unstructured":"Asodiya FA, Kumar V, Vora SD, Singh VK, Fefar DT, Gajera HP. Preparation, characterization, and xenotransplantation of the caprine acellular dermal matrix. Xenotransplantation. 2019:e12572. https:\/\/doi.org\/10.1111\/xen.12572.","DOI":"10.1111\/xen.12572"},{"key":"1254_CR19","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.biomaterials.2015.08.009","volume":"69","author":"W Jia","year":"2015","unstructured":"Jia W, Tang H, Wu J, et al. Urethral tissue regeneration using collagen scaffold modified with collagen binding VEGF in a beagle model. Biomaterials. 2015;69:45\u201355.","journal-title":"Biomaterials"},{"key":"1254_CR20","doi-asserted-by":"publisher","first-page":"2427","DOI":"10.1039\/C7BM00806F","volume":"5","author":"C Shi","year":"2017","unstructured":"Shi C, Chen W, Chen B, et al. Bladder regeneration in a canine model using a bladder acellular matrix loaded with a collagen-binding bFGF. Biomater Sci. 2017;5:2427\u201336.","journal-title":"Biomater Sci"},{"key":"1254_CR21","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1016\/j.jpedsurg.2008.04.022","volume":"43","author":"SC Gopal","year":"2008","unstructured":"Gopal SC, Gangopadhyay AN, Mohan TV, et al. Use of fibrin glue in preventing urethrocutaneous fistula after hypospadias repair. J. Pediatr. Surg. 2008;43:1869\u201372.","journal-title":"J Pediatr Surg"},{"issue":"8","key":"1254_CR22","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1007\/s11255-014-0684-3","volume":"46","author":"K Abdol-Mohammad","year":"2014","unstructured":"Abdol-Mohammad K, Shabnam S, Ali T, et al. The application of tissue-engineered preputial matrix and fibrin sealant for urethral reconstruction in rabbit model. Int Urol Nephrol. 2014;46(8):1573\u201380.","journal-title":"Int Urol Nephrol"},{"key":"1254_CR23","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1097\/00006534-200103000-00016","volume":"107","author":"BL Eppley","year":"2001","unstructured":"Eppley BL. Experimental assessment of the revascularization of acellular dermis for soft-tissue augmentation. Plast Reconstr Surg. 2001;107:757\u201362.","journal-title":"Plast Reconstr Surg"},{"key":"1254_CR24","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.jpurol.2012.05.005","volume":"9","author":"S Vallasciani","year":"2013","unstructured":"Vallasciani S, Berrettini A, Nanni L, et al. Observational retrospective study on acquired megalourethra after primary proximal hypospadias repair and its recurrence after tapering. J Pediatr Urol. 2013;9:364\u20137.","journal-title":"J Pediatr Urol"},{"issue":"6","key":"1254_CR25","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1016\/j.urology.2014.07.044","volume":"84","author":"J-W Huang","year":"2014","unstructured":"Huang J-W, Xie M-K, Zhang Y, et al. Reconstruction of penile urethra with the 3-dimensional porous bladder acellular matrix in a rabbit model. Urology. 2014;84(6):1499\u2013505.","journal-title":"Urology"},{"issue":"4","key":"1254_CR26","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.jpurol.2018.06.004","volume":"14","author":"W Snodgrass","year":"2018","unstructured":"Snodgrass W, Bush N. Is distal hypospadias repair mostly a cosmetic operation? J Pediatr Urol. 2018;14(4):339\u201340.","journal-title":"J Pediatr Urol"},{"key":"1254_CR27","doi-asserted-by":"publisher","first-page":"2098","DOI":"10.1016\/S0022-5347(01)66117-2","volume":"155","author":"BP Kropp","year":"1996","unstructured":"Kropp BP, Rippy MK, Badylak SF, et al. Regenerative urinary bladder augmentation using small intestinal submucosa: urodynamic and histopathologic assessment in long-term canine bladder augmentations. J Urol. 1996;155:2098.","journal-title":"J Urol"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-020-01254-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12325-020-01254-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-020-01254-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T09:40:20Z","timestamp":1613295620000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12325-020-01254-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,15]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["1254"],"URL":"https:\/\/doi.org\/10.1007\/s12325-020-01254-9","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,15]]},"assertion":[{"value":"13 January 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 February 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}