{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:40:32Z","timestamp":1793644832662,"version":"4.5.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T00:00:00Z","timestamp":1621382400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T00:00:00Z","timestamp":1621382400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"GlaxoSmithKline Biologicals SA"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s12325-021-01717-7","type":"journal-article","created":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T15:02:53Z","timestamp":1621436573000},"page":"3325-3341","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Economic Burden and Impact on Quality of Life of Herpes Zoster in Spanish Adults Aged 50\u00a0Years or Older: A Prospective Cohort Study"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1008-3922","authenticated-orcid":false,"given":"Javier","family":"D\u00edez-Domingo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7423-0111","authenticated-orcid":false,"given":"Desmond","family":"Curran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0241-6566","authenticated-orcid":false,"given":"Maria del Rosario","family":"Cambronero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5330-6343","authenticated-orcid":false,"given":"Juan-Antonio","family":"Garcia-Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7427-7326","authenticated-orcid":false,"given":"Sean","family":"Matthews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,19]]},"reference":[{"key":"1717_CR1","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1056\/NEJMcp1302674","volume":"369","author":"JI Cohen","year":"2013","unstructured":"Cohen JI. Clinical practice: herpes zoster. N Engl J Med. 2013;369:255\u201363.","journal-title":"N Engl J Med"},{"key":"1717_CR2","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.ijid.2015.03.022","volume":"34","author":"K Kawai","year":"2015","unstructured":"Kawai K, Rampakakis E, Tsai TF, et al. Predictors of postherpetic neuralgia in patients with herpes zoster: a pooled analysis of prospective cohort studies from North and Latin America and Asia. Int J Infect Dis. 2015;34:126\u201331.","journal-title":"Int J Infect Dis"},{"key":"1717_CR3","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1086\/421942","volume":"39","author":"J Katz","year":"2004","unstructured":"Katz J, Cooper EM, Walther RR, Sweeney EW, Dworkin RH. Acute pain in herpes zoster and its impact on health-related quality of life. Clin Infect Dis. 2004;39:342\u20138.","journal-title":"Clin Infect Dis"},{"key":"1717_CR4","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jpain.2004.06.001","volume":"5","author":"PM Coplan","year":"2004","unstructured":"Coplan PM, Schmader K, Nikas A, et al. Development of a measure of the burden of pain due to herpes zoster and postherpetic neuralgia for prevention trials: adaptation of the brief pain inventory. J Pain. 2004;5:344\u201356.","journal-title":"J Pain"},{"key":"1717_CR5","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.jpain.2005.01.359","volume":"6","author":"G Oster","year":"2005","unstructured":"Oster G, Harding G, Dukes E, Edelsberg J, Cleary PD. Pain, medication use, and health-related quality of life in older persons with postherpetic neuralgia: results from a population-based survey. J Pain. 2005;6:356\u201363.","journal-title":"J Pain"},{"key":"1717_CR6","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1097\/AJP.0b013e318065b6c9","volume":"23","author":"KE Schmader","year":"2007","unstructured":"Schmader KE, Sloane R, Pieper C, et al. The impact of acute herpes zoster pain and discomfort on functional status and quality of life in older adults. Clin J Pain. 2007;23:490\u20136.","journal-title":"Clin J Pain"},{"key":"1717_CR7","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/1741-7015-8-37","volume":"8","author":"RW Johnson","year":"2010","unstructured":"Johnson RW, Bouhassira D, Kassianos G, Leplege A, Schmader KE, Weinke T. The impact of herpes zoster and post-herpetic neuralgia on quality-of-life. BMC Med. 2010;8:37.","journal-title":"BMC Med"},{"key":"1717_CR8","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1186\/1471-2334-14-402","volume":"14","author":"A Gater","year":"2014","unstructured":"Gater A, Abetz-Webb L, Carroll S, Mannan A, Serpell M, Johnson R. Burden of herpes zoster in the UK: findings from the zoster quality of life (ZQOL) study. BMC Infect Dis. 2014;14:402.","journal-title":"BMC Infect Dis"},{"key":"1717_CR9","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1503\/cmaj.091711","volume":"182","author":"M Drolet","year":"2010","unstructured":"Drolet M, Brisson M, Schmader KE, et al. The impact of herpes zoster and postherpetic neuralgia on health-related quality of life: a prospective study. CMAJ. 2010;182:1731\u20136.","journal-title":"CMAJ"},{"key":"1717_CR10","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1186\/s12889-015-1514-y","volume":"15","author":"A Gater","year":"2015","unstructured":"Gater A, Uhart M, McCool R, Preaud E. The humanistic, economic and societal burden of herpes zoster in Europe: a critical review. BMC Public Health. 2015;15:193.","journal-title":"BMC Public Health"},{"key":"1717_CR11","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s12877-017-0420-9","volume":"17","author":"L Varghese","year":"2017","unstructured":"Varghese L, Standaert B, Olivieri A, Curran D. The temporal impact of aging on the burden of herpes zoster. BMC Geriatr. 2017;17:30.","journal-title":"BMC Geriatr"},{"key":"1717_CR12","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1186\/1471-2334-13-170","volume":"13","author":"S Pinchinat","year":"2013","unstructured":"Pinchinat S, Cebri\u00e1n-Cuenca AM, Bricout H, Johnson RW. Similar herpes zoster incidence across Europe: results from a systematic literature review. BMC Infect Dis. 2013;13:170.","journal-title":"BMC Infect Dis"},{"key":"1717_CR13","doi-asserted-by":"publisher","first-page":"100882","DOI":"10.1016\/j.pmedr.2019.100882","volume":"14","author":"A Salvetti","year":"2019","unstructured":"Salvetti A, Ferrari V, Garofalo R, et al. Incidence of herpes zoster and postherpetic neuralgia in Italian adults aged >\/=50years: a prospective study. Prev Med Rep. 2019;14:100882.","journal-title":"Prev Med Rep"},{"key":"1717_CR14","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.jinf.2018.02.001","volume":"76","author":"R Schmidt-Ott","year":"2018","unstructured":"Schmidt-Ott R, Schutter U, Simon J, et al. Incidence and costs of herpes zoster and postherpetic neuralgia in German adults aged >\/=50 years: a prospective study. J Infect. 2018;76:475\u201382.","journal-title":"J Infect"},{"key":"1717_CR15","doi-asserted-by":"publisher","first-page":"e020528","DOI":"10.1136\/bmjopen-2017-020528","volume":"8","author":"EA Yanni","year":"2018","unstructured":"Yanni EA, Ferreira G, Guennec M, et al. Burden of herpes zoster in 16 selected immunocompromised populations in England: a cohort study in the Clinical Practice Research Datalink 2000\u20132012. BMJ Open. 2018;8:e020528.","journal-title":"BMJ Open"},{"key":"1717_CR16","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1186\/s12879-020-05648-6","volume":"20","author":"C Mu\u00f1oz-Quiles","year":"2020","unstructured":"Mu\u00f1oz-Quiles C, Lopez-Lacort M, Diez-Domingo J, Orrico-Sanchez A. Herpes zoster risk and burden of disease in immunocompromised populations: a population-based study using health system integrated databases, 2009\u20132014. BMC Infect Dis. 2020;20:905.","journal-title":"BMC Infect Dis"},{"key":"1717_CR17","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1186\/s12879-018-3121-x","volume":"18","author":"C Munoz-Quiles","year":"2018","unstructured":"Munoz-Quiles C, Lopez-Lacort M, Diez-Domingo J. Risk and impact of herpes zoster among COPD patients: a population-based study, 2009\u20132014. BMC Infect Dis. 2018;18:203.","journal-title":"BMC Infect Dis"},{"key":"1717_CR18","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1186\/1471-2334-13-463","volume":"13","author":"N Morant-Talamante","year":"2013","unstructured":"Morant-Talamante N, Diez-Domingo J, Martinez-Ubeda S, Puig-Barbera J, Aleman-Sanchez S, Perez-Breva L. Herpes zoster surveillance using electronic databases in the Valencian Community (Spain). BMC Infect Dis. 2013;13:463.","journal-title":"BMC Infect Dis"},{"key":"1717_CR19","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.jinf.2018.04.004","volume":"77","author":"C Munoz-Quiles","year":"2018","unstructured":"Munoz-Quiles C, Lopez-Lacort M, Orrico-Sanchez A, Diez-Domingo J. Impact of postherpetic neuralgia: a six year population-based analysis on people aged 50 years or older. J Infect. 2018;77:131\u20136.","journal-title":"J Infect"},{"key":"1717_CR20","doi-asserted-by":"publisher","first-page":"178","DOI":"10.4161\/hv.34421","volume":"11","author":"L Salleras","year":"2015","unstructured":"Salleras L, Salleras M, Salvador P, et al. Herpes zoster and postherpetic neuralgia in Catalonia (Spain). Hum Vaccin Immunother. 2015;11:178\u201384.","journal-title":"Hum Vaccin Immunother"},{"key":"1717_CR21","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1186\/1471-2334-11-302","volume":"11","author":"AM Cebri\u00e1n-Cuenca","year":"2011","unstructured":"Cebri\u00e1n-Cuenca AM, Diez-Domingo J, San-Martin-Rodriguez M, Puig-Barbera J, Navarro-Perez J, Herpes Zoster Research Group of the Valencian Community. Epidemiology and cost of herpes zoster and postherpetic neuralgia among patients treated in primary care centres in the Valencian community of Spain. BMC Infect Dis. 2011;11:302.","journal-title":"BMC Infect Dis"},{"key":"1717_CR22","first-page":"449","volume":"55","author":"A Sicras-Mainar","year":"2012","unstructured":"Sicras-Mainar A, Navarro-Artieda R, Ibanez-Nolla J, Perez-Ronco J. Incidence, resource use and costs associated with postherpetic neuralgia: a population-based retrospective study. Rev Neurol. 2012;55:449\u201361.","journal-title":"Rev Neurol"},{"key":"1717_CR23","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s10389-011-0481-8","volume":"20","author":"K Lukas","year":"2012","unstructured":"Lukas K, Edte A, Bertrand I. The impact of herpes zoster and post-herpetic neuralgia on quality of life: patient-reported outcomes in six European countries. Z Gesundh Wiss. 2012;20:441\u201351.","journal-title":"Z Gesundh Wiss"},{"key":"1717_CR24","doi-asserted-by":"crossref","unstructured":"Curran D, Oostvogels L, Heineman T, et al. Quality of life impact of a recombinant zoster vaccine in adults aged 50 years and older. J Gerontol A Biol Sci Med Sci. 2019;74(8): 1231\u20138.","DOI":"10.1093\/gerona\/gly150"},{"key":"1717_CR25","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1186\/s12879-018-3395-z","volume":"18","author":"D Curran","year":"2018","unstructured":"Curran D, Schmidt-Ott R, Schutter U, Simon J, Anastassopoulou A, Matthews S. Impact of herpes zoster and postherpetic neuralgia on the quality of life of Germans aged 50 or above. BMC Infect Dis. 2018;18:496.","journal-title":"BMC Infect Dis"},{"key":"1717_CR26","doi-asserted-by":"publisher","first-page":"ofz007","DOI":"10.1093\/ofid\/ofz007","volume":"6","author":"S Matthews","year":"2019","unstructured":"Matthews S, De Maria A, Passamonti M, et al. The economic burden and impact on quality of life of herpes zoster and postherpetic neuralgia in individuals aged 50 years or older in Italy. Open Forum Infect Dis. 2019;6:ofz007.","journal-title":"Open Forum Infect Dis"},{"key":"1717_CR27","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s40261-017-0581-5","volume":"38","author":"A Mizukami","year":"2018","unstructured":"Mizukami A, Sato K, Adachi K, et al. Impact of herpes zoster and post-herpetic neuralgia on health-related quality of life in Japanese adults aged 60 years or older: results from a prospective observational cohort study. Clin Drug Investig. 2018;38:29\u201337.","journal-title":"Clin Drug Investig"},{"key":"1717_CR28","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3109\/07853890109002087","volume":"33","author":"R Rabin","year":"2001","unstructured":"Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med. 2001;33:337\u201343.","journal-title":"Ann Med"},{"key":"1717_CR29","unstructured":"EuroQoL. https:\/\/euroqol.org\/. Accessed 26 Oct 2020."},{"key":"1717_CR30","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1056\/NEJMoa1603800","volume":"375","author":"AL Cunningham","year":"2016","unstructured":"Cunningham AL, Lal H, Kovac M, et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. N Engl J Med. 2016;375:1019\u201332.","journal-title":"N Engl J Med"},{"key":"1717_CR31","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/1477-7525-7-48","volume":"7","author":"S McPhail","year":"2009","unstructured":"McPhail S, Lane P, Russell T, et al. Telephone reliability of the Frenchay Activity Index and EQ-5D amongst older adults. Health Qual Life Outcomes. 2009;7:48.","journal-title":"Health Qual Life Outcomes"},{"key":"1717_CR32","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s12955-017-0596-x","volume":"15","author":"R Chatterji","year":"2017","unstructured":"Chatterji R, Naylor JM, Harris IA, et al. An equivalence study: are patient-completed and telephone interview equivalent modes of administration for the EuroQol survey? Health Qual Life Outcomes. 2017;15:18.","journal-title":"Health Qual Life Outcomes"},{"key":"1717_CR33","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1177\/0272989X0102100102","volume":"21","author":"X Badia","year":"2001","unstructured":"Badia X, Roset M, Herdman M, Kind P. A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Med Decis Making. 2001;21:7\u201316.","journal-title":"Med Decis Making"},{"key":"1717_CR34","unstructured":"Consejer\u00eda de Sanidad y Asuntos Sociales, 17\/11\/2014 Official Tariffs of Healthcare Services. http:\/\/noticias.juridicas.com\/base_datos\/CCAA\/539877-orden-sanidad-y-asuntos-sociales-17-nov-2014-ca-castilla-la-mancha-precios.html. Accessed 14 Mar 2019."},{"key":"1717_CR35","unstructured":"BotPLUS web database. Official General Council of the College of Pharmacists of Spain. Madrid. https:\/\/botplusweb.portalfarma.com\/. Accessed 14 Mar 2019."},{"key":"1717_CR36","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/1471-2334-9-55","volume":"9","author":"A Gil","year":"2009","unstructured":"Gil A, Gil R, Alvaro A, San Martin M, Gonzalez A. Burden of herpes zoster requiring hospitalization in Spain during a seven-year period (1998\u20132004). BMC Infect Dis. 2009;9:55.","journal-title":"BMC Infect Dis"},{"key":"1717_CR37","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1002\/acr.22125","volume":"66","author":"I Garcia","year":"2014","unstructured":"Garcia I, Portugal C, Chu LH, Kawatkar AA. Response rates of three modes of survey administration and survey preferences of rheumatoid arthritis patients. Arthritis Care Res (Hoboken). 2014;66:364\u201370.","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"1717_CR38","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.ijid.2013.11.018","volume":"20","author":"H Song","year":"2014","unstructured":"Song H, Lee J, Lee M, et al. Burden of illness, quality of life, and healthcare utilization among patients with herpes zoster in South Korea: a prospective clinical-epidemiological study. Int J Infect Dis. 2014;20:23\u201330.","journal-title":"Int J Infect Dis"},{"key":"1717_CR39","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/1477-7525-12-92","volume":"12","author":"M Serpell","year":"2014","unstructured":"Serpell M, Gater A, Carroll S, Abetz-Webb L, Mannan A, Johnson R. Burden of post-herpetic neuralgia in a sample of UK residents aged 50 years or older: findings from the Zoster Quality of Life (ZQOL) study. Health Qual Life Outcomes. 2014;12:92.","journal-title":"Health Qual Life Outcomes"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-021-01717-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-021-01717-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-021-01717-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T23:50:24Z","timestamp":1623282624000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-021-01717-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,19]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["1717"],"URL":"https:\/\/doi.org\/10.1007\/s12325-021-01717-7","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,19]]},"assertion":[{"value":"22 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}