{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:48:31Z","timestamp":1782776911922,"version":"3.54.5"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T00:00:00Z","timestamp":1634688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T00:00:00Z","timestamp":1634688000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81702242"],"award-info":[{"award-number":["81702242"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1007\/s12325-021-01954-w","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T14:33:35Z","timestamp":1635172415000},"page":"5671-5683","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Selective Mediastinal Lymphadenectomy or Complete Mediastinal Lymphadenectomy for Clinical Stage I Non-Small Cell Lung Cancer: A Meta-Analysis"],"prefix":"10.1007","volume":"38","author":[{"given":"Ji","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shize","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4354-0635","authenticated-orcid":false,"given":"Siyuan","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,20]]},"reference":[{"key":"1954_CR1","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3322\/caac.21565","volume":"69","author":"KD Miller","year":"2019","unstructured":"Miller KD, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019;69:363\u201385. https:\/\/doi.org\/10.3322\/caac.21565.","journal-title":"CA Cancer J Clin"},{"key":"1954_CR2","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1056\/NEJMra0802714","volume":"359","author":"RS Herbst","year":"2008","unstructured":"Herbst RS, Heymach JV, Lippman SM. Lung cancer. N Engl J Med. 2008;359:1367\u201380. https:\/\/doi.org\/10.1056\/NEJMra0802714.","journal-title":"N Engl J Med"},{"key":"1954_CR3","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1093\/ejcts\/ezw083","volume":"50","author":"D Meng","year":"2016","unstructured":"Meng D, et al. Lymphadenectomy for clinical early-stage non-small-cell lung cancer: a systematic review and meta-analysis. Eur J Cardio-Thorac Surg. 2016;50:597\u2013604. https:\/\/doi.org\/10.1093\/ejcts\/ezw083.","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"1954_CR4","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1016\/j.jtho.2020.06.009","volume":"15","author":"MA Ray","year":"2020","unstructured":"Ray MA, Smeltzer MP, Faris NR, Osarogiagbon RU. Survival after mediastinal node dissection, systematic sampling, or neither for early stage NSCLC. J Thorac Oncol. 2020;15:1670\u201381. https:\/\/doi.org\/10.1016\/j.jtho.2020.06.009.","journal-title":"J Thorac Oncol"},{"key":"1954_CR5","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1093\/ejcts\/ezaa369","volume":"59","author":"TZ Abughararah","year":"2021","unstructured":"Abughararah TZ, et al. Lobe-specific lymph node dissection in stage IA non-small-cell lung cancer: a retrospective cohort study. Eur J Cardio-Yhorac Surg. 2021;59:783\u201390. https:\/\/doi.org\/10.1093\/ejcts\/ezaa369.","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"1954_CR6","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1378\/chest.12-3069","volume":"144","author":"M Shapiro","year":"2013","unstructured":"Shapiro M, et al. Lobe-specific mediastinal nodal dissection is sufficient during lobectomy by video-assisted thoracic surgery or thoracotomy for early-stage lung cancer. Chest. 2013;144:1615\u201321. https:\/\/doi.org\/10.1378\/chest.12-3069.","journal-title":"Chest"},{"key":"1954_CR7","doi-asserted-by":"publisher","first-page":"e201","DOI":"10.1016\/j.cllc.2020.09.012","volume":"22","author":"Y Zhao","year":"2021","unstructured":"Zhao Y, et al. Lobe-specific lymph node dissection in clinical stage IA solid-dominant non-small-cell lung cancer: a propensity score matching study. Clin Lung Cancer. 2021;22:e201\u201310. https:\/\/doi.org\/10.1016\/j.cllc.2020.09.012.","journal-title":"Clin Lung Cancer"},{"key":"1954_CR8","doi-asserted-by":"publisher","first-page":"e59","DOI":"10.1093\/ejcts\/ezt195","volume":"44","author":"T Maniwa","year":"2013","unstructured":"Maniwa T, et al. Recurrence of mediastinal node cancer after lobe-specific systematic nodal dissection for non-small-cell lung cancer. Eur J Cardio-Thorac Surg. 2013;44:e59-64. https:\/\/doi.org\/10.1093\/ejcts\/ezt195.","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"1954_CR9","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1136\/jech.52.6.377","volume":"52","author":"SH Downs","year":"1998","unstructured":"Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health. 1998;52:377\u201384. https:\/\/doi.org\/10.1136\/jech.52.6.377.","journal-title":"J Epidemiol Community Health"},{"key":"1954_CR10","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1007\/s00268-014-2804-8","volume":"39","author":"S Dong","year":"2015","unstructured":"Dong S, et al. Systematic mediastinal lymphadenectomy or mediastinal lymph node sampling in patients with pathological stage I NSCLC: a meta-analysis. World J Surg. 2015;39:410\u20136. https:\/\/doi.org\/10.1007\/s00268-014-2804-8.","journal-title":"World J Surg"},{"key":"1954_CR11","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700","volume":"339","author":"A Liberati","year":"2009","unstructured":"Liberati A, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009;339: b2700. https:\/\/doi.org\/10.1136\/bmj.b2700.","journal-title":"BMJ"},{"key":"1954_CR12","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1016\/j.athoracsur.2005.09.078","volume":"81","author":"M Okada","year":"2006","unstructured":"Okada M, et al. Selective mediastinal lymphadenectomy for clinico-surgical stage I non-small cell lung cancer. Ann Thorac Surg. 2006;81:1028\u201332. https:\/\/doi.org\/10.1016\/j.athoracsur.2005.09.078.","journal-title":"Ann Thorac Surg"},{"key":"1954_CR13","doi-asserted-by":"publisher","first-page":"531","DOI":"10.3779\/j.issn.1009-3419.2012.09.05","volume":"15","author":"J Chen","year":"2012","unstructured":"Chen J, Mao F, Song Z, Shen-Tu Y. Retrospective study on lobe-specific lymph node dissection for patients with early-stage non-small cell lung cancer. Zhongguo Fei Ai Za Zhi. 2012;15:531\u20138. https:\/\/doi.org\/10.3779\/j.issn.1009-3419.2012.09.05.","journal-title":"Zhongguo Fei Ai Za Zhi"},{"key":"1954_CR14","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1007\/s00268-012-1849-9","volume":"37","author":"W Jiang","year":"2013","unstructured":"Jiang W, Chen X, Xi J, Wang Q. Selective mediastinal lymphadenectomy without intraoperative frozen section examinations for clinical stage I non-small-cell lung cancer: retrospective study of 403 cases. World J Surg. 2013;37:392\u20137. https:\/\/doi.org\/10.1007\/s00268-012-1849-9.","journal-title":"World J Surg"},{"issue":"Suppl 2","key":"1954_CR15","doi-asserted-by":"publisher","first-page":"S101","DOI":"10.4103\/0973-1482.119119","volume":"9","author":"W Ma","year":"2013","unstructured":"Ma W, Zhang ZJ, Li Y, Ma GY, Zhang L. Comparison of lobe-specific mediastinal lymphadenectomy versus systematic mediastinal lymphadenectomy for clinical stage T1a N0 M0 non-small cell lung cancer. J Cancer Res Ther. 2013;9(Suppl 2):S101-105. https:\/\/doi.org\/10.4103\/0973-1482.119119.","journal-title":"J Cancer Res Ther"},{"key":"1954_CR16","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1016\/j.jtho.2016.05.014","volume":"11","author":"T Hishida","year":"2016","unstructured":"Hishida T, et al. Lobe-specific nodal dissection for clinical stage I and II NSCLC: Japanese multi-institutional retrospective study using a propensity score analysis. J Thorac Oncol. 2016;11:1529\u201337. https:\/\/doi.org\/10.1016\/j.jtho.2016.05.014.","journal-title":"J Thorac Oncol"},{"key":"1954_CR17","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1016\/s1470-2045(15)00621-x","volume":"17","author":"EF Patz Jr","year":"2016","unstructured":"Patz EF Jr, et al. Lung cancer incidence and mortality in National Lung Screening Trial participants who underwent low-dose CT prevalence screening: a retrospective cohort analysis of a randomised, multicentre, diagnostic screening trial. Lancet Oncol. 2016;17:590\u20139. https:\/\/doi.org\/10.1016\/s1470-2045(15)00621-x.","journal-title":"Lancet Oncol"},{"key":"1954_CR18","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1016\/s0022-5223(99)70246-1","volume":"117","author":"H Asamura","year":"1999","unstructured":"Asamura H, Nakayama H, Kondo H, Tsuchiya R, Naruke T. Lobe-specific extent of systematic lymph node dissection for non-small cell lung carcinomas according to a retrospective study of metastasis and prognosis. J Thorac Cardiovasc Surg. 1999;117:1102\u201311. https:\/\/doi.org\/10.1016\/s0022-5223(99)70246-1.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1954_CR19","doi-asserted-by":"publisher","first-page":"2102","DOI":"10.21037\/jtd.2017.06.04","volume":"9","author":"H Han","year":"2017","unstructured":"Han H, Chen H. Selective lymph node dissection in early-stage non-small cell lung cancer. J Thorac Dis. 2017;9:2102\u20137. https:\/\/doi.org\/10.21037\/jtd.2017.06.04.","journal-title":"J Thorac Dis"},{"key":"1954_CR20","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1016\/j.jtcvs.2009.07.024","volume":"139","author":"F Ishiguro","year":"2010","unstructured":"Ishiguro F, et al. Effect of selective lymph node dissection based on patterns of lobe-specific lymph node metastases on patient outcome in patients with resectable non-small cell lung cancer: a large-scale retrospective cohort study applying a propensity score. J Thorac Cardiovasc Surg. 2010;139:1001\u20136. https:\/\/doi.org\/10.1016\/j.jtcvs.2009.07.024.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1954_CR21","doi-asserted-by":"publisher","first-page":"e278S","DOI":"10.1378\/chest.12-2359","volume":"143","author":"JA Howington","year":"2013","unstructured":"Howington JA, Blum MG, Chang AC, Balekian AA, Murthy SC. Treatment of stage I and II non-small cell lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013;143:e278S-e313S. https:\/\/doi.org\/10.1378\/chest.12-2359.","journal-title":"Chest"},{"key":"1954_CR22","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1016\/j.athoracsur.2019.10.056","volume":"109","author":"HY Deng","year":"2020","unstructured":"Deng HY, et al. Surgical choice for clinical stage IA non-small cell lung cancer: view from regional lymph node metastasis. Ann Thorac Surg. 2020;109:1079\u201385. https:\/\/doi.org\/10.1016\/j.athoracsur.2019.10.056.","journal-title":"Ann Thorac Surg"},{"key":"1954_CR23","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1093\/jjco\/hyx170","volume":"48","author":"T Hishida","year":"2018","unstructured":"Hishida T, et al. A randomized Phase III trial of lobe-specific vs systematic nodal dissection for clinical Stage I-II non-small cell lung cancer (JCOG1413). Jpn J Clin Oncol. 2018;48:190\u20134. https:\/\/doi.org\/10.1093\/jjco\/hyx170.","journal-title":"Jpn J Clin Oncol"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-021-01954-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-021-01954-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-021-01954-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,6]],"date-time":"2021-11-06T19:12:02Z","timestamp":1636225922000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-021-01954-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,20]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1954"],"URL":"https:\/\/doi.org\/10.1007\/s12325-021-01954-w","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,20]]},"assertion":[{"value":"21 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}