{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T04:05:16Z","timestamp":1788753916622,"version":"build-2803163510"},"reference-count":91,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T00:00:00Z","timestamp":1654905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T00:00:00Z","timestamp":1654905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1007\/s12325-022-02191-5","type":"journal-article","created":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T09:02:44Z","timestamp":1654938164000},"page":"3449-3471","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Benign Peripheral Non-cranial Nerve Sheath Tumors of the Neck"],"prefix":"10.1007","volume":"39","author":[{"given":"Carlos","family":"Su\u00e1rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7019-9746","authenticated-orcid":false,"given":"Fernando","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan P.","family":"Rodrigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William M.","family":"Mendenhall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remco","family":"de Bree","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antti A.","family":"M\u00e4kitie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Vander Poorten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P.","family":"Takes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Bondi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz P.","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok R.","family":"Shaha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Fern\u00e1ndez-Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio C.","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Zidar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Chiesa-Estomba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Primoz","family":"Strojan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"Sanabria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Rinaldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfio","family":"Ferlito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,6,11]]},"reference":[{"key":"2191_CR1","volume":"7","author":"WL Ramey","year":"2015","unstructured":"Ramey WL, Arnold SJ, Chiu A, Lemole M. A rare case of optic nerve schwannoma: case report and review of the literature. Cureus. 2015;7: e265.","journal-title":"Cureus"},{"key":"2191_CR2","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/S0090-3019(03)00537-8","volume":"61","author":"P Conti","year":"2004","unstructured":"Conti P, Pansini G, Mouchaty H, Capuano C, Conti R. Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature. Surg Neurol. 2004;61:34\u201343.","journal-title":"Surg Neurol"},{"key":"2191_CR3","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1227\/NEU.0b013e31822d276a","volume":"70","author":"KI Desai","year":"2012","unstructured":"Desai KI. Primary benign brachial plexus tumors: an experience of 115 operated cases. Neurosurgery. 2012;70:220\u201333.","journal-title":"Neurosurgery"},{"key":"2191_CR4","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1227\/01.NEU.0000367636.91555.70","volume":"66","author":"AD Levi","year":"2010","unstructured":"Levi AD, Ross AL, Cuartas E, Qadir R, Temple HT. The surgical management of symptomatic peripheral nerve sheath tumors. Neurosurgery. 2010;66:833\u201340.","journal-title":"Neurosurgery"},{"key":"2191_CR5","doi-asserted-by":"publisher","first-page":"372","DOI":"10.3171\/2009.5.JNS09244","volume":"112","author":"MN Herbert-Blouin","year":"2010","unstructured":"Herbert-Blouin MN, Amrami KK, Scheithauer BW, Spinner RJ. Multinodular\/plexiform (multifascicular) schwannomas of major peripheral nerves: an under recognized part of the spectrum of schwannomas. J Neurosurg. 2010;112:372\u201382.","journal-title":"J Neurosurg"},{"key":"2191_CR6","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3171\/2015.3.SPINE141145","volume":"24","author":"P Li","year":"2016","unstructured":"Li P, Zhao F, Zhang J, et al. Clinical features of spinal schwannomas in 65 patients with schwannomatosis compared with 831 with solitary schwannomas and 102 with neurofibromatosis type\u00a02: a retrospective study at a single institution. J Neurosurg Spine. 2016;24:145\u201354.","journal-title":"J Neurosurg Spine"},{"issue":"11","key":"2191_CR7","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1136\/jnnp-2018-318538","volume":"89","author":"DG Evans","year":"2018","unstructured":"Evans DG, Bowers NL, Tobi S, et al. Schwannomatosis: a genetic and epidemiological study. J Neurol Neurosurg Psychiatry. 2018;89(11):1215\u20139. https:\/\/doi.org\/10.1136\/jnnp-2018-318538.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2191_CR8","doi-asserted-by":"publisher","first-page":"246","DOI":"10.3171\/jns.2005.102.2.0246","volume":"102","author":"DH Kim","year":"2005","unstructured":"Kim DH, Murovic JA, Tiel RL, Moes G, Kline DG. A series of 397 peripheral neural sheath tumors: 30-year experience at Louisiana State University Health Sciences Center. J Neurosurg. 2005;102:246\u201355.","journal-title":"J Neurosurg"},{"key":"2191_CR9","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1136\/jmg.39.5.311","volume":"39","author":"D Evans","year":"2002","unstructured":"Evans D, Baser M, McGaughran J, Sharif S, Howard E, Moran A. Malignant peripheral nerve sheath tumours in neurofibromatosis 1. J Med Genet. 2002;39:311\u20134.","journal-title":"J Med Genet"},{"key":"2191_CR10","doi-asserted-by":"publisher","first-page":"717","DOI":"10.4143\/crt.2016.271","volume":"49","author":"IK Hwang","year":"2017","unstructured":"Hwang IK, Hahn SM, Kim HS, et al. Outcomes of treatment for malignant peripheral nerve sheath tumors: different clinical features associated with neurofibromatosis type 1. Cancer Res Treat. 2017;49:717\u201326.","journal-title":"Cancer Res Treat"},{"key":"2191_CR11","doi-asserted-by":"publisher","first-page":"2365","DOI":"10.1007\/s00405-013-2520-2","volume":"270","author":"S Bondi","year":"2013","unstructured":"Bondi S, Limardo P, Toma S, Bussi M. Non-vestibular head and neck schwannomas: a 10-year experience. Eur Arch Otorhinolaryngol. 2013;270:2365\u20139.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"2191_CR12","doi-asserted-by":"publisher","first-page":"494","DOI":"10.3171\/2016.9.SPINE16778","volume":"26","author":"M Sowash","year":"2017","unstructured":"Sowash M, Barzilai O, Kahn S, et al. Clinical outcomes following resection of giant spinal schwannomas: a case series of 32 patients. J Neurosurg Spine. 2017;26:494\u2013500.","journal-title":"J Neurosurg Spine"},{"key":"2191_CR13","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1046\/j.1365-2559.1999.00786.x","volume":"35","author":"AV Vallat-Decouvelaere","year":"1999","unstructured":"Vallat-Decouvelaere AV, Wassef M, Lot G, et al. Spinal melanotic schwannoma: a tumour with poor prognosis. Histopathology. 1999;35:558\u201366.","journal-title":"Histopathology"},{"key":"2191_CR14","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/s11060-016-2286-7","volume":"131","author":"M D\u2019Astous","year":"2017","unstructured":"D\u2019Astous M, Ho AL, Pendharkar A, et al. Stereotactic radiosurgery for non-vestibular cranial nerve schwanommas. J Neurooncol. 2017;131:177\u201383.","journal-title":"J Neurooncol"},{"key":"2191_CR15","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1258\/0022215001905058","volume":"114","author":"MP Colreavy","year":"2000","unstructured":"Colreavy MP, Lacy PD, Hughes J, et al. Head and neck schwannomas\u2014a 10 year review. J Laryngol Otol. 2000;114:119\u201324.","journal-title":"J Laryngol Otol"},{"key":"2191_CR16","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1097\/SCS.0b013e3181a14cbc","volume":"20","author":"JO Guerrissi","year":"2009","unstructured":"Guerrissi JO. Solitary benign schwannomas in major nerve systems of the head and neck. J Craniofac Surg. 2009;20:957\u201361.","journal-title":"J Craniofac Surg"},{"key":"2191_CR17","doi-asserted-by":"crossref","first-page":"233","DOI":"10.47102\/annals-acadmedsg.V36N4p233","volume":"36","author":"GC Kang","year":"2007","unstructured":"Kang GC, Soo KC, Lim DT. Extracranial non-vestibular head and neck schwannomas: a ten-year experience. Ann Acad Med Singapore. 2007;36:233\u20138.","journal-title":"Ann Acad Med Singapore"},{"key":"2191_CR18","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.15537\/smj.2015.11.12314","volume":"36","author":"B Wang","year":"2015","unstructured":"Wang B, Yuan J, Chen X, Xu H, Zhou Y, Dong P. Extracranial non-vestibular head and neck schwannomas. Saudi Med J. 2015;36:1363\u20136.","journal-title":"Saudi Med J"},{"key":"2191_CR19","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1097\/MLG.0b013e31817b0702","volume":"118","author":"CE de Araujo","year":"2008","unstructured":"de Araujo CE, Ramos DM, Moyses RA, Durazzo MD, Cernea CR, Ferraz AR. Neck nerve trunks schwannomas: clinical features and postoperative neurologic outcome. Laryngoscope. 2008;118:1579\u201382.","journal-title":"Laryngoscope"},{"key":"2191_CR20","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/973045","volume":"2013","author":"R Yasumatsu","year":"2013","unstructured":"Yasumatsu R, Nakashima T, Miyazaki R, Segawa Y, Komune S. Diagnosis and management of extracranial head and neck schwannomas: a review of 27 cases. Int J Otolaryngol. 2013;2013: 973045.","journal-title":"Int J Otolaryngol"},{"key":"2191_CR21","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1001\/jamaoto.2016.0113","volume":"142","author":"K Ijichi","year":"2016","unstructured":"Ijichi K, Kawakita D, Maseki S, Beppu S, Takano G, Murakami S. Functional nerve preservation in extracranial head and neck schwannoma surgery. JAMA Otolaryngol Head Neck Surg. 2016;142:479\u201383.","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"21","key":"2191_CR22","first-page":"00109","volume":"S1808\u20138694","author":"D Dosemane","year":"2021","unstructured":"Dosemane D, Kabekkodu S, Jaipuria B, Sreedharan S, Shenoy V. Extracranial non-vestibular head and neck schwannomas: a case series with the review of literature. Braz J Otorhinolaryngol. 2021;S1808\u20138694(21):00109\u201319.","journal-title":"Braz J Otorhinolaryngol"},{"key":"2191_CR23","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1097\/MOO.0000000000000147","volume":"23","author":"JL Netterville","year":"2015","unstructured":"Netterville JL, Groom K. Function-sparing intracapsular enucleation of cervical schwannomas. Curr Opin Otolaryngol Head Neck Surg. 2015;23:176\u20139.","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"2191_CR24","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1002\/hed.25021","volume":"40","author":"Y Sato","year":"2018","unstructured":"Sato Y, Imanishi Y, Tomita T, et al. Clinical diagnosis and treatment outcomes for parapharyngeal space schwannomas: a single-institution review of 21 cases. Head Neck. 2018;40:569\u201376.","journal-title":"Head Neck"},{"key":"2191_CR25","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1080\/00016480260000157","volume":"122","author":"YS Leu","year":"2002","unstructured":"Leu YS, Chang KC. Extracranial head and neck schwannomas: a review of 8 years experience. Acta Otolaryngol. 2002;122:435\u20137.","journal-title":"Acta Otolaryngol"},{"key":"2191_CR26","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1177\/0194599814549550","volume":"151","author":"M Navaie","year":"2014","unstructured":"Navaie M, Sharghi LH, Cho-Reyes S, Keefe MA, Howie BA, Setzen G. Diagnostic approach, treatment, and outcomes of cervical sympathetic chain schwannomas: a global narrative review. Otolaryngol Head Neck Surg. 2014;151:899\u2013908.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"2191_CR27","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1002\/hed.24523","volume":"39","author":"X Zheng","year":"2017","unstructured":"Zheng X, Guo K, Wang H, et al. Extracranial schwannoma in the carotid space: a retrospective review of 91 cases. Head Neck. 2017;39:42\u20137.","journal-title":"Head Neck"},{"key":"2191_CR28","volume":"9","author":"SA Itawi","year":"2017","unstructured":"Itawi SA, Buehler M, Mrak RE, Mansour TR, Medhkour Y, Medhkour A. A unique case of carotid splaying by a cervical vagal neurofibroma and the role of neuroradiology in surgical management. Cureus. 2017;9: e1658.","journal-title":"Cureus"},{"key":"2191_CR29","unstructured":"IARC. WHO classification of head and neck tumours, volume 6. Central nervous system tumours. 5th\u00a0ed. Lyon: International Agency for Research on Cancer; 2021."},{"key":"2191_CR30","doi-asserted-by":"publisher","first-page":"73","DOI":"10.14639\/0392-100X-1170","volume":"38","author":"M Simone","year":"2018","unstructured":"Simone M, Vesperini E, Viti C, Camaioni A, Lepanto L, Raso F. Intraparotid facial nerve schwannoma: two case reports and a review of the literature. Acta Otorhinolaryngol Ital. 2018;38:73\u20137.","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"2191_CR31","doi-asserted-by":"publisher","first-page":"71","DOI":"10.7181\/acfs.2018.02250","volume":"20","author":"BF Seo","year":"2019","unstructured":"Seo BF, Choi HJ, Seo KJ, Jung SN. Intraparotid facial nerve schwannomas. Arch Craniofac Surg. 2019;20:71\u20134.","journal-title":"Arch Craniofac Surg"},{"key":"2191_CR32","first-page":"569","volume":"52","author":"I Nazari","year":"2014","unstructured":"Nazari I, Esfehani MH, Nouri M, Naeemi AR, Salimi J, Zafarghandi MR. Cervical sympathetic schwannoma: report of two cases and review of the literature. Acta Med Iran. 2014;52:569\u201374.","journal-title":"Acta Med Iran"},{"key":"2191_CR33","doi-asserted-by":"publisher","first-page":"2695","DOI":"10.1002\/hed.25520","volume":"40","author":"D Ahn","year":"2018","unstructured":"Ahn D, Lee GJ, Sohn JH, Jeong JY. Fine-needle aspiration cytology versus core-needle biopsy for the diagnosis of extracranial head and neck schwannoma. Head Neck. 2018;40:2695\u2013700.","journal-title":"Head Neck"},{"key":"2191_CR34","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1002\/hed.23050","volume":"35","author":"A Langerman","year":"2013","unstructured":"Langerman A, Rangarajan SV, Athavale SM, Pham MQ, Sinard RJ, Netterville JL. Tumors of the cervical sympathetic chain\u2013diagnosis and management. Head Neck. 2013;35:930\u20133.","journal-title":"Head Neck"},{"key":"2191_CR35","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1093\/neuros\/nyx076","volume":"81","author":"KI Desai","year":"2017","unstructured":"Desai KI. The surgical management of symptomatic benign peripheral nerve sheath tumors of the neck and extremities: an experience of 442 cases. Neurosurgery. 2017;81:568\u201380.","journal-title":"Neurosurgery"},{"key":"2191_CR36","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1097\/COC.0000000000000219","volume":"41","author":"SM Kharod","year":"2018","unstructured":"Kharod SM, Herman MP, Amdur RJ, Mendenhall WM. Fractionated radiation therapy for benign nonacoustic schwannomas. Am J Clin Oncol. 2018;41:13\u20137.","journal-title":"Am J Clin Oncol"},{"issue":"5","key":"2191_CR37","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.3390\/cancers13051140","volume":"13","author":"Y Shinya","year":"2021","unstructured":"Shinya Y, Hasegawa H, Shin M, et al. Long-term outcomes of stereotactic radiosurgery for trigeminal, facial, and jugular foramen schwannoma in comparison with vestibular schwannoma. Cancers (Basel). 2021;13(5):1140.","journal-title":"Cancers (Basel)"},{"key":"2191_CR38","doi-asserted-by":"crossref","unstructured":"Laurent D, Smith AE, Bessler WK, et al. Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival. Neurooncol Adv 2021;3:vdab063.","DOI":"10.1093\/noajnl\/vdab063"},{"key":"2191_CR39","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1002\/humu.23552","volume":"39","author":"M Carri\u00f3","year":"2018","unstructured":"Carri\u00f3 M, Gel B, Terribas E, et al. Analysis of intratumor heterogeneity in neurofibromatosis type 1 plexiform neurofibromas and neurofibromas with atypical features: correlating histological and genomic findings. Hum Mutat. 2018;39:1112\u201325.","journal-title":"Hum Mutat"},{"key":"2191_CR40","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1080\/0284186X.2019.1601255","volume":"58","author":"K Lindberg","year":"2019","unstructured":"Lindberg K, Grozman V, Lindberg S, Onjukka E, Lax I, Lewensohn R, Wers\u00e4ll P. Radiation-induced brachial plexus toxicity after SBRT of apically located lung lesions. Acta Oncol. 2019;58:1178\u201386.","journal-title":"Acta Oncol"},{"key":"2191_CR41","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1308\/003588414X14055925058355","volume":"97","author":"S Behuria","year":"2015","unstructured":"Behuria S, Rout TK, Pattanayak S. Diagnosis and management of schwannomas originating from the cervical vagus nerve. Ann R Coll Surg Eng. 2015;97:92\u20137.","journal-title":"Ann R Coll Surg Eng"},{"key":"2191_CR42","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1093\/ons\/opz034","volume":"18","author":"JJ Stone","year":"2020","unstructured":"Stone JJ, Spinner RJ. Go for the gold: a \u201cplane\u201d and simple technique for resecting benign peripheral nerve sheath tumors. Oper Neurosurg (Hagerstown). 2020;18:60\u20138.","journal-title":"Oper Neurosurg (Hagerstown)"},{"key":"2191_CR43","doi-asserted-by":"publisher","first-page":"655392","DOI":"10.3389\/fonc.2021.655392","volume":"11","author":"MT Pedro","year":"2021","unstructured":"Pedro MT, Gr\u00fcbel N, Durner G, Pala A, Wirtz CR, Koenig RW. Intraoperative sodium-fluorescence imaging in peripheral nerve sheath tumors (PNST)\u2014a new additional promising diagnostic tool. Front Oncol. 2021;11:655392.","journal-title":"Front Oncol"},{"key":"2191_CR44","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/hed.25439","volume":"41","author":"F L\u00f3pez","year":"2019","unstructured":"L\u00f3pez F, Suarez C, Vander Poorten V, et al. Contemporary management of primary parapharyngeal space tumors. Head Neck. 2019;41:522\u201335.","journal-title":"Head Neck"},{"key":"2191_CR45","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1016\/j.bjoms.2014.08.002","volume":"52","author":"WL Chen","year":"2014","unstructured":"Chen WL, Wang YY, Zhang DM, Huang ZQ. Endoscopy-assisted transoral resection of large benign parapharyngeal space tumors. Br J Oral Maxillofac Surg. 2014;52:970\u20133.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"2191_CR46","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1177\/0300060518816190","volume":"47","author":"Z Chen","year":"2019","unstructured":"Chen Z, Chen YL, Yu Q, et al. Excision of tumors in the parapharyngeal space using an endoscopically assisted transoral approach: a case series and literature review. J Int Med Res. 2019;47:1103\u201313.","journal-title":"J Int Med Res"},{"key":"2191_CR47","doi-asserted-by":"publisher","DOI":"10.1002\/rcs.2083","volume":"16","author":"N Sethi","year":"2020","unstructured":"Sethi N, Dale O, Vidhyadharan S, Krishnan S, Foreman A, Hodge JC. Transoral robotic narrow field oropharyngectomy for tumours of the parapharyngeal space. Int J Med Robot. 2020;16: e2083.","journal-title":"Int J Med Robot"},{"key":"2191_CR48","doi-asserted-by":"publisher","first-page":"4535","DOI":"10.1245\/s10434-020-08536-0","volume":"27","author":"JY Lim","year":"2020","unstructured":"Lim JY, Park YM, Kang MS, et al. Comparison of surgical outcomes of robotic and conventional approaches in patients with pre- and poststyloid parapharyngeal space tumors. Ann Surg Oncol. 2020;27:4535\u201343.","journal-title":"Ann Surg Oncol"},{"key":"2191_CR49","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s11701-019-00932-3","volume":"14","author":"S Panda","year":"2020","unstructured":"Panda S, Sikka K, Thakar A, Sharma SC, Krishnamurthy P. Transoral robotic surgery for the parapharyngeal space: expanding the transoral corridor. J Robot Surg. 2020;14:61\u20137.","journal-title":"J Robot Surg"},{"key":"2191_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.104581","volume":"103","author":"A De Virgilio","year":"2020","unstructured":"De Virgilio A, Costantino A, Mercante G, Di Maio P, Iocca O, Spriano G. Trans-oral robotic surgery in the management of parapharyngeal space tumors: a systematic review. Oral Oncol. 2020;103: 104581.","journal-title":"Oral Oncol"},{"key":"2191_CR51","doi-asserted-by":"publisher","first-page":"3305","DOI":"10.1007\/s00405-014-2953-2","volume":"271","author":"P Nicolai","year":"2014","unstructured":"Nicolai P, Paderno A, Farina D, Piazza C. Microdebrider cavitation and transcervical removal of parapharyngeal schwannomas approaching the skull base. Eur Arch Otorhinolaryngol. 2014;271:3305\u201311.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"2191_CR52","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1007\/s00701-009-0380-8","volume":"151","author":"MG Siqueira","year":"2009","unstructured":"Siqueira MG, Martins RS, Teixeira MJ. Management of brachial plexus region tumours and tumour-like conditions: relevant diagnostic and surgical features in a consecutive series of eighteen patients. Acta Neurochir (Wien). 2009;151:1089\u201398.","journal-title":"Acta Neurochir (Wien)"},{"key":"2191_CR53","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3171\/jns.2001.95.1.0051","volume":"95","author":"A Ganju","year":"2001","unstructured":"Ganju A, Roosen N, Kline DG, Tiel RL. Outcomes in a consecutive series of 111 surgically treated plexal tumors: a review of the experience at the Louisiana State University Health Sciences Center. J Neurosurg. 2001;95:51\u201360.","journal-title":"J Neurosurg"},{"key":"2191_CR54","doi-asserted-by":"publisher","first-page":"625","DOI":"10.3340\/jkns.2018.0045","volume":"61","author":"IH Jung","year":"2018","unstructured":"Jung IH, Yoon KW, Kim YJ, Lee SK. Analysis according to characteristics of 18 cases of brachial plexus tumors: a review of surgical treatment experience. J Korean Neurosurg Soc. 2018;61:625\u201332.","journal-title":"J Korean Neurosurg Soc"},{"key":"2191_CR55","doi-asserted-by":"publisher","first-page":"E11","DOI":"10.3171\/foc.2004.16.5.12","volume":"16","author":"DK Binder","year":"2004","unstructured":"Binder DK, Smith JS, Barbaro NM. Primary brachial plexus tumors: imaging, surgical, and pathological findings in 25 patients. Neurosurg Focus. 2004;16:E11.","journal-title":"Neurosurg Focus"},{"key":"2191_CR56","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.surneu.2003.08.006","volume":"61","author":"JH Huang","year":"2004","unstructured":"Huang JH, Zaghloul K, Zager EL. Surgical management of brachial plexus region tumors. Surg Neurol. 2004;61:372\u20138.","journal-title":"Surg Neurol"},{"key":"2191_CR57","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1007\/BF01410969","volume":"139","author":"M Artico","year":"1997","unstructured":"Artico M, Cervoni L, Wierzbicki V, D\u2019Andrea V, Nucci F. Benign neural sheath tumours of major nerves: characteristics in 119 surgical cases. Acta Neurochir (Wien). 1997;139:1108\u201316.","journal-title":"Acta Neurochir (Wien)"},{"key":"2191_CR58","doi-asserted-by":"crossref","unstructured":"Dubuisson AS, Kline DG, Weinshel SS. Posterior subscapular approach to the brachial plexus. Report of 102 patients. J Neurosurg. 1993;79:319\u2013330.","DOI":"10.3171\/jns.1993.79.3.0319"},{"key":"2191_CR59","doi-asserted-by":"crossref","unstructured":"Dubuisson A, Reuter G, Kaschten B, et al. Management of benign nerve sheath tumors of the brachial plexus: relevant diagnostic and surgical features. About a series of 17 patients (19 tumors) and review of the literature. Acta Neurol Belg. 2021;121:125\u2013131.","DOI":"10.1007\/s13760-020-01560-7"},{"key":"2191_CR60","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1186\/s12883-019-1532-y","volume":"19","author":"C Xu","year":"2019","unstructured":"Xu C, Sun Q. Great auricular nerve schwannoma in neck region: a case report with the risk of medical disputes. BMC Neurol. 2019;19:308.","journal-title":"BMC Neurol"},{"key":"2191_CR61","first-page":"380","volume":"43","author":"H Tanaka","year":"1995","unstructured":"Tanaka H, Iuchi K, Mori T, Tanaka Y, Ikeda M, Nanjou S. A case of schwannoma of intrathoracic right phrenic nerve. Nippon Kyobu Geka Gakai Zasshi. 1995;43:380\u20133.","journal-title":"Nippon Kyobu Geka Gakai Zasshi"},{"key":"2191_CR62","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.amjoto.2006.10.007","volume":"28","author":"G De Bie","year":"2007","unstructured":"De Bie G, Legrand A, Mahillon V, Lemort M, Gilles A, Saussez S. Schwannoma of the accessory phrenic nerve. Am J Otolaryngol. 2007;28:357\u20139.","journal-title":"Am J Otolaryngol"},{"key":"2191_CR63","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.anorl.2012.01.001","volume":"129","author":"SM Gilani","year":"2012","unstructured":"Gilani SM, Danforth RD. Intractable hiccups: a rare presentation of phrenic nerve schwannoma. Eur Ann Otorhinolaryngol Head Neck Dis. 2012;129:331\u20133.","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"},{"key":"2191_CR64","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s00701-009-0338-x","volume":"152","author":"H Arishima","year":"2010","unstructured":"Arishima H, Streichenberger N, Sindou M. Successful excision of a rare cervical neurofibroma arising from the phrenic nerve: a case report. Acta Neurochir (Wien). 2010;152:327\u20138.","journal-title":"Acta Neurochir (Wien)"},{"key":"2191_CR65","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/S0385-8146(03)00005-1","volume":"30","author":"E Mevio","year":"2003","unstructured":"Mevio E, Gorini E, Sbrocca M, et al. Unusual cases of cervical nerves schwannomas: phrenic and vagus nerve involvement. Auris Nasus Larynx. 2003;30:209\u201313.","journal-title":"Auris Nasus Larynx"},{"key":"2191_CR66","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.bjoms.2007.03.002","volume":"46","author":"RM Graham","year":"2008","unstructured":"Graham RM, Thomson EF, Woodwards RT. Benign schwannoma of the left cervical phrenic nerve. Br J Oral Maxillofac Surg. 2008;46:161\u20132.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"2191_CR67","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.anl.2004.09.005","volume":"32","author":"N Watanabe","year":"2005","unstructured":"Watanabe N, Moriwaki K. Preoperative anticipation of origin from MRI scans in cervical phrenic schwannoma. Auris Nasus Larynx. 2005;32:85\u20138.","journal-title":"Auris Nasus Larynx"},{"key":"2191_CR68","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000008381","author":"TK Nicoli","year":"2021","unstructured":"Nicoli TK, Saat R, Tarkkanen J, Kinnunen I, M\u00e4kitie AA, Jero J. Challenging management of plexiform schwannoma and plexiform neurofibroma. J Craniofac Surg. 2021. https:\/\/doi.org\/10.1097\/SCS.0000000000008381.","journal-title":"J Craniofac Surg"},{"key":"2191_CR69","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1056\/NEJMoa1912735","volume":"382","author":"AM Gross","year":"2020","unstructured":"Gross AM, Wolters PL, Dombi E, et al. Selumetinib in children with inoperable plexiform neurofibromas. N Engl J Med. 2020;382:1430\u201342.","journal-title":"N Engl J Med"},{"key":"2191_CR70","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1038\/s41591-020-01193-6","volume":"27","author":"MJ Fisher","year":"2021","unstructured":"Fisher MJ, Shih CS, Rhodes SD, et al. Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial. Nat Med. 2021;27:165\u201373.","journal-title":"Nat Med"},{"key":"2191_CR71","doi-asserted-by":"publisher","first-page":"3556","DOI":"10.1002\/cam4.3910","volume":"10","author":"R Ronsley","year":"2021","unstructured":"Ronsley R, Hounjet CD, Cheng S, et al. Trametinib therapy for children with neurofibromatosis type 1 and life-threatening plexiform neurofibroma or treatment-refractory low-grade glioma. Cancer Med. 2021;10:3556\u201364.","journal-title":"Cancer Med"},{"key":"2191_CR72","doi-asserted-by":"publisher","first-page":"6032","DOI":"10.3390\/cancers13236032","volume":"13","author":"LD Sanchez","year":"2021","unstructured":"Sanchez LD, Bui A, Klesse LJ. Targeted therapies for the neurofibromatoses. Cancers (Basel). 2021;13:6032.","journal-title":"Cancers (Basel)"},{"key":"2191_CR73","doi-asserted-by":"publisher","first-page":"2285","DOI":"10.1007\/s00381-020-04771-8","volume":"36","author":"E Legius","year":"2020","unstructured":"Legius E, Brems H. Genetic basis of neurofibromatosis type 1 and related conditions, including mosaicism. Childs Nerv Syst. 2020;36:2285\u201395.","journal-title":"Childs Nerv Syst"},{"key":"2191_CR74","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1227\/01.NEU.0000153752.59565.BB","volume":"56","author":"T Jinnai","year":"2005","unstructured":"Jinnai T, Koyama T. Clinical characteristics of spinal nerve sheath tumors: analysis of 149 cases. Neurosurgery. 2005;56:510\u20135.","journal-title":"Neurosurgery"},{"key":"2191_CR75","first-page":"217","volume":"27","author":"E Emel","year":"2017","unstructured":"Emel E, Abdallah A, Sofuoglu OE, et al. Long-term surgical outcomes of spinal schwannomas: retrospective analysis of 49 consecutive cases. Turk Neurosurg. 2017;27:217\u201325.","journal-title":"Turk Neurosurg"},{"key":"2191_CR76","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1097\/00006123-199710000-00010","volume":"41","author":"G Lot","year":"1997","unstructured":"Lot G, George B. Cervical neuromas with extradural components: surgical management in a series of 57 patients. Neurosurgery. 1997;41:813\u201320.","journal-title":"Neurosurgery"},{"key":"2191_CR77","doi-asserted-by":"publisher","first-page":"587","DOI":"10.3171\/SPI-07\/12\/587","volume":"7","author":"H Ozawa","year":"2007","unstructured":"Ozawa H, Kokubun S, Aizawa T, Hoshikawa T, Kawahara C. Spinal dumbbell tumors: an analysis of a series of 118 cases. J Neurosurg Spine. 2007;7:587\u201393.","journal-title":"J Neurosurg Spine"},{"key":"2191_CR78","doi-asserted-by":"publisher","first-page":"917","DOI":"10.3171\/jns.1995.82.6.0917","volume":"82","author":"B George","year":"1995","unstructured":"George B, Lot G. Neurinomas of the first two cervical nerve roots: a series of 42 cases. J Neurosurg. 1995;82:917\u201323.","journal-title":"J Neurosurg"},{"key":"2191_CR79","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3171\/2016.5.SPINE15974","volume":"26","author":"MM Safaee","year":"2017","unstructured":"Safaee MM, Lyon R, Barbaro NM, et al. Neurological outcomes and surgical complications in 221 spinal nerve sheath tumors. J Neurosurg Spine. 2017;26:103\u201311.","journal-title":"J Neurosurg Spine"},{"key":"2191_CR80","doi-asserted-by":"publisher","first-page":"318","DOI":"10.3389\/fneur.2017.00318","volume":"8","author":"I Sun","year":"2017","unstructured":"Sun I, Pamir MN. Non-syndromic spinal schwannomas: a novel classification. Front Neurol. 2017;8:318.","journal-title":"Front Neurol"},{"key":"2191_CR81","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1080\/02688699943042","volume":"13","author":"W El-Mahdy","year":"1999","unstructured":"El-Mahdy W, Kane PJ, Powell MP, Crockard HA. Spinal intradural tumours: part i-extramedullary. Br J Neurosurg. 1999;13:550\u20137.","journal-title":"Br J Neurosurg"},{"key":"2191_CR82","doi-asserted-by":"crossref","unstructured":"Fehlings MG, Nater A, Zamorano JJ, et al. Risk factors for recurrence of surgically treated conventional spinal schwannomas: analysis of 169 patients from a multicenter international database. Spine (Phila Pa 1976). 2016;41:390\u2013398.","DOI":"10.1097\/BRS.0000000000001232"},{"key":"2191_CR83","doi-asserted-by":"publisher","first-page":"447","DOI":"10.3171\/spi.2005.2.4.0447","volume":"2","author":"P Celli","year":"2005","unstructured":"Celli P, Trill\u00f2 G, Ferrante L. Spinal extradural schwannoma. J Neurosurg Spine. 2005;2:447\u201356.","journal-title":"J Neurosurg Spine"},{"key":"2191_CR84","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1002\/bjs.18002811205","volume":"28","author":"K Eden","year":"1941","unstructured":"Eden K. The dumb-bell tumors of the spine. Br J Surg. 1941;28:549\u201370.","journal-title":"Br J Surg"},{"key":"2191_CR85","doi-asserted-by":"publisher","first-page":"E10","DOI":"10.1097\/01.BRS.0000103662.13689.76","volume":"29","author":"T Asazuma","year":"2004","unstructured":"Asazuma T, Toyama Y, Maruiwa H, Fujimura Y, Hirabayashi K. Surgical strategy for cervical dumbbell tumors based on a three-dimensional classification. Spine. 2004;29:E10\u20134.","journal-title":"Spine"},{"key":"2191_CR86","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.3171\/2010.5.JNS0966","volume":"114","author":"DD Cavalcanti","year":"2011","unstructured":"Cavalcanti DD, Martirosyan NL, Verma K, et al. Surgical management and outcome of schwannomas in the craniocervical region. J Neurosurg. 2011;114:1257\u201367.","journal-title":"J Neurosurg"},{"key":"2191_CR87","first-page":"59","volume":"22","author":"FH Chowdhury","year":"2013","unstructured":"Chowdhury FH, Haque MR, Sarker MH. High cervical spinal schwannoma; microneurosurgical management: an experience of 15 cases. Acta Neurol Taiwan. 2013;22:59\u201366.","journal-title":"Acta Neurol Taiwan"},{"key":"2191_CR88","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1097\/00006123-199602000-00012","volume":"38","author":"PC McCormick","year":"1996","unstructured":"McCormick PC. Surgical management of dumbbell tumors of the cervical spine. Neurosurgery. 1996;38:294\u2013300.","journal-title":"Neurosurgery"},{"issue":"6","key":"2191_CR89","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.3171\/jns.1984.61.6.1100","volume":"61","author":"A Hakuba","year":"1984","unstructured":"Hakuba A, Komiyama M, Tsujimoto T, et al. Transuncodiscal approach to dumbbell tumors of the cervical spinal canal. J Neurosurg. 1984;61(6):1100\u20136.","journal-title":"J Neurosurg"},{"key":"2191_CR90","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1038\/modpathol.2014.109","volume":"28","author":"M Pekmezci","year":"2015","unstructured":"Pekmezci M, Reuss DE, Hirbe AC, et al. Morphologic and immunohistochemical features of malignant peripheral nerve sheath tumors and cellular schwannomas. Mod Pathol. 2015;28:187\u2013200.","journal-title":"Mod Pathol"},{"key":"2191_CR91","first-page":"343","volume":"67","author":"K Yamane","year":"2013","unstructured":"Yamane K, Takigawa T, Tanaka M, Osaki S, Sugimoto Y, Ozaki T. Factors predicting clinical impairment after surgery for cervical spinal schwannoma. Acta Med Okayama. 2013;67:343\u20139.","journal-title":"Acta Med Okayama"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-022-02191-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-022-02191-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-022-02191-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T23:39:46Z","timestamp":1700696386000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-022-02191-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,11]]},"references-count":91,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["2191"],"URL":"https:\/\/doi.org\/10.1007\/s12325-022-02191-5","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,11]]},"assertion":[{"value":"1 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 June 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}