{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T05:31:09Z","timestamp":1792992669678,"version":"4.5.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100002973","name":"Daiichi-Sankyo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002973","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100008976","name":"Sanofi-Aventis Korea Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008976","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hanmi Pharmaceutical Co. Ltd"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1007\/s12325-023-02632-9","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T07:03:01Z","timestamp":1693465381000},"page":"4817-4835","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan\/Amlodipine\/Hydrochlorothiazide in Korean Patients with Hypertension and Cardiovascular Risk Factors"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4585-1488","authenticated-orcid":false,"given":"Jaewon","family":"Oh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7036-449X","authenticated-orcid":false,"given":"Wonho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0279-7370","authenticated-orcid":false,"given":"Gee-Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6703-1472","authenticated-orcid":false,"given":"Hack-Lyoung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0128-9988","authenticated-orcid":false,"given":"Sang-Don","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Wan","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9318-5985","authenticated-orcid":false,"given":"Dongkeun","family":"Hyun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8693-1038","authenticated-orcid":false,"given":"Jun Hwa","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4137-1671","authenticated-orcid":false,"given":"Soo","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2872-6105","authenticated-orcid":false,"given":"Jinho","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"RESOLVE-INT Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Su","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Hwan","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangwon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Guk","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hoon","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang Su","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaemin","family":"Shim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young\u2011dae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-il","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hyung","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bong Gu","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Gu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Seung","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Hun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Yeop","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Yul","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Wan","family":"Chun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang Je","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Eun","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pum-Joon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Won","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun Seok","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Beom","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Hoon","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Goo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Won","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Gu","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo Joo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Guk","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Jin","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Jae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oh-Hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eui","family":"Im","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Wook","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Hwan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyu Hwan","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Min","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Jin","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seo Hye","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Kyung","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu-Jeung","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho Yeon","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won-Chul","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Won","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Sam","family":"Baik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Pil","family":"Joo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ung","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Hwan","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Hong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Jeong","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hancheol","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.-Hyun","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan Seok","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Woong","family":"Roh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaechun","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Myung","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye Soo","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinje","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Rak","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Hee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Hyo","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun Seong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Bae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moo Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moo Young","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"2632_CR1","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1161\/CIRCULATIONAHA.115.018912","volume":"134","author":"KT Mills","year":"2016","unstructured":"Mills KT, Bundy JD, Kelly TN, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016;134:441\u201350. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.115.018912.","journal-title":"Circulation"},{"key":"2632_CR2","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s40885-019-0121-0","volume":"25","author":"HC Kim","year":"2019","unstructured":"Kim HC, Ihm S-H, Kim G-H, et al. 2018 Korean Society of Hypertension guidelines for the management of hypertension: part I-epidemiology of hypertension. Clin Hypertens. 2019;25:16. https:\/\/doi.org\/10.1186\/s40885-019-0121-0.","journal-title":"Clin Hypertens"},{"key":"2632_CR3","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s40885-018-0098-0","volume":"24","author":"HC Kim","year":"2018","unstructured":"Korean Society Hypertension, Hypertension Epidemiology Research Working Group, Kim HC, Cho M-C. Korea hypertension fact sheet 2018. Clin Hypertens. 2018;24:13. https:\/\/doi.org\/10.1186\/s40885-018-0098-0.","journal-title":"Clin Hypertens"},{"key":"2632_CR4","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1111\/jch.14444","volume":"24","author":"EW Edwards","year":"2022","unstructured":"Edwards EW, Saari HD, DiPette DJ. Inadequate hypertension control rates: a global concern for countries of all income levels. J Clin Hypertens (Greenwich). 2022;24:362\u20134. https:\/\/doi.org\/10.1111\/jch.14444.","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"2632_CR5","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s40885-019-0124-x","volume":"25","author":"H-Y Lee","year":"2019","unstructured":"Lee H-Y, Shin J, Kim G-H, et al. 2018 Korean Society of Hypertension Guidelines for the management of hypertension: part II-diagnosis and treatment of hypertension. Clin Hypertens. 2019;25:20. https:\/\/doi.org\/10.1186\/s40885-019-0124-x.","journal-title":"Clin Hypertens"},{"key":"2632_CR6","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.amjmed.2008.09.038","volume":"122","author":"DS Wald","year":"2009","unstructured":"Wald DS, Law M, Morris JK, Bestwick JP, Wald NJ. Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials. Am J Med. 2009;122:290\u2013300. https:\/\/doi.org\/10.1016\/j.amjmed.2008.09.038.","journal-title":"Am J Med"},{"key":"2632_CR7","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.amjmed.2006.08.033","volume":"120","author":"S Bangalore","year":"2007","unstructured":"Bangalore S, Kamalakkannan G, Parkar S, Messerli FH. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med. 2007;120:713\u20139. https:\/\/doi.org\/10.1016\/j.amjmed.2006.08.033.","journal-title":"Am J Med"},{"key":"2632_CR8","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1093\/ndt\/gfk064","volume":"21","author":"JM Neutel","year":"2006","unstructured":"Neutel JM. The role of combination therapy in the management of hypertension. Nephrol Dial Transplant. 2006;21:1469\u201373. https:\/\/doi.org\/10.1093\/ndt\/gfk064.","journal-title":"Nephrol Dial Transplant"},{"key":"2632_CR9","doi-asserted-by":"publisher","first-page":"255","DOI":"10.18553\/jmcp.2016.22.3.255","volume":"22","author":"M Levi","year":"2016","unstructured":"Levi M, Pasqua A, Cricelli I, et al. Patient adherence to olmesartan\/amlodipine combinations: fixed versus extemporaneous combinations. J Manag Care Spec Pharm. 2016;22:255\u201362. https:\/\/doi.org\/10.18553\/jmcp.2016.22.3.255.","journal-title":"J Manag Care Spec Pharm"},{"key":"2632_CR10","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.1097\/HJH.0000000000001940","volume":"36","author":"B Williams","year":"2018","unstructured":"Williams B, Mancia G, Spiering W, et al. 2018 ESC\/ESH Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension: the task force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. J Hypertens. 2018;36:1953\u20132041. https:\/\/doi.org\/10.1097\/HJH.0000000000001940.","journal-title":"J Hypertens"},{"key":"2632_CR11","doi-asserted-by":"publisher","first-page":"e127","DOI":"10.1016\/j.jacc.2017.11.006","volume":"71","author":"PK Whelton","year":"2018","unstructured":"Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APhA\/ASH\/ASPC\/NMA\/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2018;71:e127-248. https:\/\/doi.org\/10.1016\/j.jacc.2017.11.006.","journal-title":"J Am Coll Cardiol"},{"key":"2632_CR12","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1016\/j.clinthera.2010.07.008","volume":"32","author":"S Oparil","year":"2010","unstructured":"Oparil S, Melino M, Lee J, Fernandez V, Heyrman R. Triple therapy with olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide in adult patients with hypertension: the TRINITY multicenter, randomized, double-blind, 12-week, parallel-group study. Clin Ther. 2010;32:1252\u201369. https:\/\/doi.org\/10.1016\/j.clinthera.2010.07.008.","journal-title":"Clin Ther"},{"key":"2632_CR13","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1007\/BF03261919","volume":"32","author":"M Volpe","year":"2012","unstructured":"Volpe M, Christian Rump L, Ammentorp B, Laeis P. Efficacy and safety of triple antihypertensive therapy with the olmesartan\/amlodipine\/hydrochlorothiazide combination. Clin Drug Investig. 2012;32:649\u201364. https:\/\/doi.org\/10.1007\/BF03261919.","journal-title":"Clin Drug Investig"},{"key":"2632_CR14","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s12325-014-0117-9","volume":"31","author":"M Volpe","year":"2014","unstructured":"Volpe M, de la Sierra A, Ammentorp B, Laeis P. Open-label study assessing the long-term efficacy and safety of triple olmesartan\/amlodipine\/hydrochlorothiazide combination therapy for hypertension. Adv Ther. 2014;31:561\u201374. https:\/\/doi.org\/10.1007\/s12325-014-0117-9.","journal-title":"Adv Ther"},{"key":"2632_CR15","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/1475-2840-11-134","volume":"11","author":"DJ Kereiakes","year":"2012","unstructured":"Kereiakes DJ, Chrysant SG, Izzo JLJ, et al. Olmesartan\/amlodipine\/hydrochlorothiazide in participants with hypertension and diabetes, chronic kidney disease, or chronic cardiovascular disease: a subanalysis of the multicenter, randomized, double-blind, parallel-group TRINITY study. Cardiovasc Diabetol. 2012;11:134. https:\/\/doi.org\/10.1186\/1475-2840-11-134.","journal-title":"Cardiovasc Diabetol"},{"key":"2632_CR16","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s40885-021-00177-z","volume":"27","author":"IS Sohn","year":"2021","unstructured":"Sohn IS, Ihm S-H, Kim GH, et al. Real-world evidence on the strategy of olmesartan-based triple single-pill combination in Korean hypertensive patients: a prospective, multicenter, observational study (RESOLVE-PRO). Clin Hypertens. 2021;27:21. https:\/\/doi.org\/10.1186\/s40885-021-00177-z.","journal-title":"Clin Hypertens"},{"key":"2632_CR17","doi-asserted-by":"publisher","first-page":"3500","DOI":"10.1007\/s12325-020-01404-z","volume":"37","author":"S-J Park","year":"2020","unstructured":"Park S-J, Rhee SJ. Real-world effectiveness and safety of a single-pill combination of olmesartan\/amlodipine\/hydrochlorothiazide in Korean Patients with Essential Hypertension (RESOLVE): a large, observational, retrospective, cohort study. Adv Ther. 2020;37:3500\u201314. https:\/\/doi.org\/10.1007\/s12325-020-01404-z.","journal-title":"Adv Ther"},{"key":"2632_CR18","doi-asserted-by":"publisher","first-page":"3S","DOI":"10.1016\/s0895-7061(99)00252-6","volume":"13","author":"WB Kannel","year":"2000","unstructured":"Kannel WB. Risk stratification in hypertension: new insights from the Framingham Study. Am J Hypertens. 2000;13:3S\u201310S. https:\/\/doi.org\/10.1016\/s0895-7061(99)00252-6.","journal-title":"Am J Hypertens"},{"key":"2632_CR19","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.ijcard.2017.12.026","volume":"254","author":"M Volpe","year":"2018","unstructured":"Volpe M, Gallo G, Tocci G. Is early and fast blood pressure control important in hypertension management? Int J Cardiol. 2018;254:328\u201332. https:\/\/doi.org\/10.1016\/j.ijcard.2017.12.026.","journal-title":"Int J Cardiol"},{"key":"2632_CR20","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s40885-014-0013-2","volume":"21","author":"J Shin","year":"2015","unstructured":"Shin J, Park JB, Kim K-I, et al. 2013 Korean Society of Hypertension guidelines for the management of hypertension. Part II-treatments of hypertension. Clin Hypertens. 2015;21:2. https:\/\/doi.org\/10.1186\/s40885-014-0013-2.","journal-title":"Clin Hypertens"},{"key":"2632_CR21","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1016\/j.amjcard.2010.12.045","volume":"107","author":"CV Ram","year":"2011","unstructured":"Ram CV, Sachson R, Littlejohn T, et al. Management of hypertension in patients with diabetes using an amlodipine-, olmesartan medoxomil-, and hydrochlorothiazide-based titration regimen. Am J Cardiol. 2011;107:1346\u201352. https:\/\/doi.org\/10.1016\/j.amjcard.2010.12.045.","journal-title":"Am J Cardiol"},{"key":"2632_CR22","unstructured":"Korean Society of Hypertension. 2022 Korean Society of Hypertension Guidelines 2022. https:\/\/www.koreanhypertension.org\/news\/notice?mode=read&idno=10008. Accessed 24 May 2023."},{"key":"2632_CR23","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1161\/01.hyp.0000035855.44620.da","volume":"40","author":"DM Lloyd-Jones","year":"2002","unstructured":"Lloyd-Jones DM, Evans JC, Larson MG, Levy D. Treatment and control of hypertension in the community: a prospective analysis. Hypertension. 2002;40:640\u20136. https:\/\/doi.org\/10.1161\/01.hyp.0000035855.44620.da.","journal-title":"Hypertension"},{"key":"2632_CR24","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1345\/aph.1K506","volume":"42","author":"D Weycker","year":"2008","unstructured":"Weycker D, Edelsberg J, Vincze G, Levy DG, Kartashov A, Oster G. Blood pressure control in patients initiating antihypertensive therapy. Ann Pharmacother. 2008;42:169\u201376. https:\/\/doi.org\/10.1345\/aph.1K506.","journal-title":"Ann Pharmacother"},{"key":"2632_CR25","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2023.38.e124","volume":"24","author":"HJ Joo","year":"2023","unstructured":"Joo HJ, Yum Y, Kim YH, et al. Gender difference of blood pressure control rate and clinical prognosis in patients with resistant hypertension: real-world observation study. J Korean Med Sci. 2023;24: e124. https:\/\/doi.org\/10.3346\/jkms.2023.38.e124.","journal-title":"J Korean Med Sci"},{"key":"2632_CR26","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1001\/jama.2010.884","volume":"304","author":"RM Cooper-DeHoff","year":"2010","unstructured":"Cooper-DeHoff RM, Gong Y, Handberg EM, et al. Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease. JAMA. 2010;304:61\u20138. https:\/\/doi.org\/10.1001\/jama.2010.884.","journal-title":"JAMA"},{"key":"2632_CR27","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1056\/NEJMoa1001286","volume":"362","author":"WC Cushman","year":"2010","unstructured":"Cushman WC, Evans GW, Byington RP, et al. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010;362:1575\u201385. https:\/\/doi.org\/10.1056\/NEJMoa1001286.","journal-title":"N Engl J Med"},{"key":"2632_CR28","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/S0140-6736(07)61303-8","volume":"370","author":"A Patel","year":"2007","unstructured":"Patel A, MacMahon S, Chalmers J, et al. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet. 2007;370:829\u201340. https:\/\/doi.org\/10.1016\/S0140-6736(07)61303-8.","journal-title":"Lancet"},{"key":"2632_CR29","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1038\/ajh.2008.191","volume":"21","author":"KI Kim","year":"2008","unstructured":"Kim KI, Kim Y, Kim HJ, et al. Current status and characteristics of hypertension treatment by primary physicians in Korea: data from Korean epidemiology study on hypertension (KEY study). Am J Hypertens. 2008;21:884\u20139. https:\/\/doi.org\/10.1038\/ajh.2008.191.","journal-title":"Am J Hypertens"},{"key":"2632_CR30","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3810\/pgm.2011.11.2495","volume":"123","author":"RM Guthrie","year":"2011","unstructured":"Guthrie RM. Review: a single-pill combination of telmisartan plus amlodipine for the treatment of hypertension. Postgrad Med. 2011;123:58\u201365. https:\/\/doi.org\/10.3810\/pgm.2011.11.2495.","journal-title":"Postgrad Med"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-023-02632-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-023-02632-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-023-02632-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T10:37:19Z","timestamp":1697020639000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-023-02632-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["2632"],"URL":"https:\/\/doi.org\/10.1007\/s12325-023-02632-9","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,31]]},"assertion":[{"value":"22 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Jaewon Oh, Wonho Kim, Gee-Hee Kim, Hack-Lyoung\u00a0Kim, Sang-Don Park, Kyung Wan Min, Dongkeun Hyun, Jun Hwa Hong, and Soo Lim declare that they have no competing interests. Jinho Shin received honoraria from Daiichi Sankyo, Organon, Bristol Myers Squibb, Menarini, Sanofi, Hanmi, Boryung, Chong Kun Dang, and Daewoong and grants from Sanofi and Hanmi.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study protocol and informed consent forms were approved by the institutional review board (IRB) of each participating institution. The study was registered with the Clinical Research Information Service (KCT0003401; ). The study was conducted in accordance with the principles of the Declaration of Helsinki 1964 and its later amendments as well as the rules of each IRB. All patients voluntarily provided written informed consent before enrollment in the study. Data were de-identified to protect the privacy of the participating patients and to be fully compliant with locally applicable regulations.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}