{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T08:40:09Z","timestamp":1750495209253,"version":"3.41.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T00:00:00Z","timestamp":1747872000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T00:00:00Z","timestamp":1747872000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100014468","name":"Mallinckrodt Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014468","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1007\/s12325-025-03232-5","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T07:35:45Z","timestamp":1747899345000},"page":"3386-3399","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Real-World Insights on Satisfaction and Experience with Acthar Gel via SelfJect (RISE\u2122): A Cross-Sectional Patient Survey"],"prefix":"10.1007","volume":"42","author":[{"given":"Jas","family":"Bindra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ishveen","family":"Chopra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyle","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Niewoehner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Panaccio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobby","family":"Trawick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1140-740X","authenticated-orcid":false,"given":"George J.","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"issue":"1","key":"3232_CR1","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1093\/rheumatology\/kei114","volume":"45","author":"MJ Cross","year":"2006","unstructured":"Cross MJ, March LM, Lapsley HM, Byrne E, Brooks PM. Patient self-efficacy and health locus of control: relationships with health status and arthritis-related expenditure. Rheumatology (Oxford). 2006;45(1):92\u20136. https:\/\/doi.org\/10.1093\/rheumatology\/kei114.","journal-title":"Rheumatology (Oxford)"},{"key":"3232_CR2","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1477-7525-9-2","volume":"9","author":"D Keininger","year":"2011","unstructured":"Keininger D, Coteur G. Assessment of self-injection experience in patients with rheumatoid arthritis: psychometric validation of the Self-Injection Assessment Questionnaire (SIAQ). Health Qual Life Outcomes. 2011;9:2. https:\/\/doi.org\/10.1186\/1477-7525-9-2.","journal-title":"Health Qual Life Outcomes"},{"issue":"10","key":"3232_CR3","doi-asserted-by":"publisher","first-page":"1969","DOI":"10.1016\/s0277-9536(03)00063-7","volume":"57","author":"P Salmon","year":"2003","unstructured":"Salmon P, Hall GM. Patient empowerment and control: a psychological discourse in the service of medicine. Soc Sci Med. 2003;57(10):1969\u201380. https:\/\/doi.org\/10.1016\/s0277-9536(03)00063-7.","journal-title":"Soc Sci Med"},{"key":"3232_CR4","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.2147\/PPA.S310086","volume":"15","author":"J Aw","year":"2021","unstructured":"Aw J, Griffiths H, Zochling J, Lanzafame A, Jordan A. Usability of the certolizumab pegol auto-injection device in Australian patients with chronic rheumatic diseases: results from a market research study. Patient Prefer Adherence. 2021;15:1469\u201376. https:\/\/doi.org\/10.2147\/PPA.S310086.","journal-title":"Patient Prefer Adherence"},{"issue":"2","key":"3232_CR5","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s40744-017-0080-4","volume":"4","author":"M Schiff","year":"2017","unstructured":"Schiff M, Saunderson S, Mountian I, Hartley P. Chronic disease and self-injection: ethnographic investigations into the patient experience during treatment. Rheumatol Ther. 2017;4(2):445\u201363. https:\/\/doi.org\/10.1007\/s40744-017-0080-4.","journal-title":"Rheumatol Ther"},{"issue":"Suppl 2","key":"3232_CR6","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1186\/ar996","volume":"6","author":"S Schwartzman","year":"2004","unstructured":"Schwartzman S, Morgan GJ. Does route of administration affect the outcome of TNF antagonist therapy? Arthritis Res Ther. 2004;6(Suppl 2):S19-23. https:\/\/doi.org\/10.1186\/ar996.","journal-title":"Arthritis Res Ther"},{"issue":"8","key":"3232_CR7","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1080\/17425247.2024.2390553","volume":"21","author":"A Linnane","year":"2024","unstructured":"Linnane A, Lau M, Miranda P, Elliott S. Formative and validation human factors studies of a new disposable prefilled injection device for subcutaneous delivery of Acthar gel (repository corticotropin injection). Expert Opin Drug Deliv. 2024;21(8):1263\u201378. https:\/\/doi.org\/10.1080\/17425247.2024.2390553.","journal-title":"Expert Opin Drug Deliv"},{"issue":"9","key":"3232_CR8","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1007\/s12325-018-0759-0","volume":"35","author":"N Maniadakis","year":"2018","unstructured":"Maniadakis N, Toth E, Schiff M, et al. A targeted literature review examining biologic therapy compliance and persistence in chronic inflammatory diseases to identify the associated unmet needs, driving factors, and consequences. Adv Ther. 2018;35(9):1333\u201355. https:\/\/doi.org\/10.1007\/s12325-018-0759-0.","journal-title":"Adv Ther"},{"issue":"1","key":"3232_CR9","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1080\/10717544.2019.1587043","volume":"26","author":"BJF van den Bemt","year":"2019","unstructured":"van den Bemt BJF, Gettings L, Domanska B, Bruggraber R, Mountian I, Kristensen LE. A portfolio of biologic self-injection devices in rheumatology: how patient involvement in device design can improve treatment experience. Drug Deliv. 2019;26(1):384\u201392. https:\/\/doi.org\/10.1080\/10717544.2019.1587043.","journal-title":"Drug Deliv"},{"issue":"3","key":"3232_CR10","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1517\/14712590903530633","volume":"10","author":"J Borras-Blasco","year":"2010","unstructured":"Borras-Blasco J, Gracia-Perez A, Rosique-Robles JD, Castera MD, Abad FJ. Acceptability of switching adalimumab from a prefilled syringe to an autoinjection pen. Expert Opin Biol Ther. 2010;10(3):301\u20137. https:\/\/doi.org\/10.1517\/14712590903530633.","journal-title":"Expert Opin Biol Ther"},{"key":"3232_CR11","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.2147\/PPA.S64111","volume":"8","author":"W Demary","year":"2014","unstructured":"Demary W, Schwenke H, Rockwitz K, et al. Subcutaneously administered methotrexate for rheumatoid arthritis, by prefilled syringes versus prefilled pens: patient preference and comparison of the self-injection experience. Patient Prefer Adherence. 2014;8:1061\u201371. https:\/\/doi.org\/10.2147\/PPA.S64111.","journal-title":"Patient Prefer Adherence"},{"issue":"10","key":"3232_CR12","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1016\/j.clinthera.2006.10.006","volume":"28","author":"A Kivitz","year":"2006","unstructured":"Kivitz A, Cohen S, Dowd JE, et al. Clinical assessment of pain, tolerability, and preference of an autoinjection pen versus a prefilled syringe for patient self-administration of the fully human, monoclonal antibody adalimumab: the TOUCH trial. Clin Ther. 2006;28(10):1619\u201329. https:\/\/doi.org\/10.1016\/j.clinthera.2006.10.006.","journal-title":"Clin Ther"},{"key":"3232_CR13","unstructured":"Mallinckrodt Pharmaceuticals. Acthar\u00ae Gel (repository corticotropin injection). https:\/\/www.acthar.com\/Static\/pdf\/Acthar-PI.pdf. Published 2024. Accessed May\u00a031, 2024."},{"key":"3232_CR14","unstructured":"Mallinckrodt Pharmaceuticals. Mallinckrodt announces availability of Acthar\u00ae Gel (repository corticotropin injection) Single-Dose Pre-filled SelfJect\u2122 Injector in the U.S. Mallinckrodt Pharmaceuticals. https:\/\/mnk.com\/about\/news-and-media\/news-detail\/?id=31081. Published 2024. Accessed August 6, 2024."},{"issue":"12","key":"3232_CR15","doi-asserted-by":"publisher","DOI":"10.57264\/cer-2024-0131","volume":"13","author":"S Elliott","year":"2024","unstructured":"Elliott S, Miranda P, Hayes K. A novel injection device to administer repository corticotropin injection for inflammatory disease treatment: findings from a market research study. J Comp Eff Res. 2024;13(12):e240131. https:\/\/doi.org\/10.57264\/cer-2024-0131.","journal-title":"J Comp Eff Res"},{"issue":"1","key":"3232_CR16","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1186\/s12955-020-01606-7","volume":"18","author":"F Pompilus","year":"2020","unstructured":"Pompilus F, Ciesluk A, Strzok S, et al. Development and psychometric evaluation of the assessment of self-injection questionnaire: an adaptation of the self-injection assessment questionnaire. Health Qual Life Outcomes. 2020;18(1):355. https:\/\/doi.org\/10.1186\/s12955-020-01606-7.","journal-title":"Health Qual Life Outcomes"},{"issue":"5","key":"3232_CR17","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1080\/17425247.2020.1736552","volume":"17","author":"BPH Pouls","year":"2020","unstructured":"Pouls BPH, Kristensen LE, Petersson M, et al. A pilot study examining patient preference and satisfaction for ava\u00ae, a reusable electronic injection device to administer certolizumab pegol. Expert Opin Drug Deliv. 2020;17(5):705\u201311. https:\/\/doi.org\/10.1080\/17425247.2020.1736552.","journal-title":"Expert Opin Drug Deliv"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-025-03232-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-025-03232-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-025-03232-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T08:14:38Z","timestamp":1750493678000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-025-03232-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,22]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["3232"],"URL":"https:\/\/doi.org\/10.1007\/s12325-025-03232-5","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"type":"print","value":"0741-238X"},{"type":"electronic","value":"1865-8652"}],"subject":[],"published":{"date-parts":[[2025,5,22]]},"assertion":[{"value":"1 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Kyle Hayes, John Niewoehner, Sheila Elliott, Bobby Trawick, and George J. Wan are employees of Mallinckrodt Pharmaceuticals and declare that they have no other conflicts of interest. Ishveen Chopra, Jas Bindra, and Mary Panaccio are paid research consultants for the study and declare that they have no other conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"An independent ethics committee (WCG IRB, Princeton, New Jersey, USA) reviewed and approved the study protocol, consent form, and survey tool. The ethics committee also granted an exemption from the requirements of federal regulation 45 CFR 46.101(b)(2) and certified this exemption status (#1-1781602-1) on July 9, 2024. This study was performed in accordance with the Helsinki Declaration of 1964 and its later amendments. Prior to participating in this online survey, all participants were presented with an information page outlining the study\u2019s purpose, procedures, and their right to withdraw at any time. By proceeding with the survey, participants indicated their informed consent to participate and for the use of their anonymized and aggregated responses for presentations and publication. This process was documented electronically.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}